Crosslinking-guided geometry of a complete CXC receptor-chemokine complex and the basis of chemokine subfamily selectivity von Ngo, Tony, Stephens, Bryan S., Gustavsson, Martin, Holden, Lauren G., Abagyan, Ruben, Handel, Tracy M., Kufareva, Irina

Volltext

Stoichiometry and geometry of the CXC chemokine receptor 4 complex with CXC ligand 12: Molecular modeling and experimental validation von Kufareva, Irina, Stephens, Bryan S, Holden, Lauren G, Qin, Ling, Zhao, Chunxia, Kawamura, Tetsuya, Abagyan, Ruben, Handel, Tracy M

Volltext

Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications von Chen, Xiaojiang S, Holden, Lauren G, Prochnow, Courtney, Chang, Y. Paul, Bransteitter, Ronda, Chelico, Linda, Sen, Udayaditya, Stevens, Raymond C, Goodman, Myron F

Volltext

Elicitation of potent serum neutralizing antibody responses in rabbits by immunization with an HIV-1 clade C trimeric Env derived from an Indian elite neutralizer von Kumar, Rajesh, Deshpande, Suprit, Sewall, Leigh M., Ozorowski, Gabriel, Cottrell, Christopher A., Lee, Wen-Hsin, Holden, Lauren G., Richey, Sara T., Chandrawacar, Antra Singh, Dhiman, Kanika, Ashish, Fnu, Kumar, Vivek, Ahmed, Shubbir, Hingankar, Nitin, Kumar, Naresh, Murugavel, Kailapuri G., Srikrishnan, Aylur K., Sok, Devin, Ward, Andrew B., Bhattacharya, Jayanta

Volltext

Crystal structure of the chemokine receptor CXCR4 in complex with a viral chemokine von Qin, Ling, Kufareva, Irina, Holden, Lauren G., Wang, Chong, Zheng, Yi, Zhao, Chunxia, Fenalti, Gustavo, Wu, Huixian, Han, Gye Won, Cherezov, Vadim, Abagyan, Ruben, Stevens, Raymond C., Handel, Tracy M.

Volltext

Characterization of a stable HIV-1 B/C recombinant, soluble, and trimeric envelope glycoprotein (Env) highly resistant to CD4-induced conformational changes von Kumar, Rajesh, Ozorowski, Gabriel, Kumar, Vivek, Holden, Lauren G., Shrivastava, Tripti, Patil, Shilpa, Deshpande, Suprit, Ward, Andrew B., Bhattacharya, Jayanta

Volltext

Disulfide Trapping for Modeling and Structure Determination of Receptor: Chemokine Complexes von Kufareva, Irina, Gustavsson, Martin, Holden, Lauren G, Qin, Ling, Zheng, Yi, Handel, Tracy M

Volltext

Improving the Expression and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers by Targeted Sequence Changes von Ringe, Rajesh P, Ozorowski, Gabriel, Yasmeen, Anila, Cupo, Albert, Cruz Portillo, Victor M, Pugach, Pavel, Golabek, Michael, Rantalainen, Kimmo, Holden, Lauren G, Cottrell, Christopher A, Wilson, Ian A, Sanders, Rogier W, Ward, Andrew B, Klasse, P J, Moore, John P

Volltext

The structure of a DnaB-family replicative helicase and its interactions with primase von Holden, Lauren G, Zhang, Yi, Wang, Ganggang, Tokonzaba, Etienne, Klein, Michael G, Chen, Xiaojiang S

Volltext

WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing von Yannone, Steven M, Tainer, John A, Perry, J Jefferson P, Holden, Lauren G, Hitomi, Chiharu, Asaithamby, Aroumougame, Han, Seungil, Cooper, Priscilla K, Chen, David J

Volltext

Identification of Amino Acids Important for the Biochemical Activity of Methanothermobacter thermautotrophicus MCM von Fletcher, Ryan J, Shen, Jingping, Holden, Lauren G, Chen, Xiaojiang S

Volltext

Associating protein activities with their genes: rapid identification of a gene encoding a methylglyoxal reductase in the yeast Saccharomyces cerevisiae von Chen, Ching‐Nen, Porubleva, Larysa, Shearer, Georgia, Svrakic, Maja, Holden, Lauren G., Dover, James L., Johnston, Mark, Chitnis, Parag R., Kohl, Daniel H.

Volltext

Stoichiometry and geometry of the CXC chemokine receptor 4 complex with CXC ligand 12: Molecular modeling and experimental validation von Kufareva, Irina, Stephens, Bryan S., Holden, Lauren G., Qin, Ling, Zhao, Chunxia, Kawamura, Tetsuya, Abagyan, Ruben, Handel, Tracy M.

Volltext

Abstract A168: Towards an understanding of the structural basis of CXCR7 ligand binding and signaling von Gustavsson, Martin, Zheng, Yi, Qin, Ling, Holden, Lauren G., Kufareva, Irina, Handel, Tracy M.

Volltext

Structural biology. Crystal structure of the chemokine receptor CXCR4 in complex with a viral chemokine von Qin, Ling, Kufareva, Irina, Holden, Lauren G, Wang, Chong, Zheng, Yi, Zhao, Chunxia, Fenalti, Gustavo, Wu, Huixian, Han, Gye Won, Cherezov, Vadim, Abagyan, Ruben, Stevens, Raymond C, Handel, Tracy M

Volltext

Vitamin d deficiency in a multiethnic healthy control cohort and altered immune response in vitamin D deficient European-American healthy controls von Ritterhouse, Lauren L, Lu, Rufei, Shah, Hemangi B, Robertson, Julie M, Fife, Dustin A, Maecker, Holden T, Du, Hongwu, Fathman, Charles G, Chakravarty, Eliza F, Scofield, R Hal, Kamen, Diane L, Guthridge, Joel M, James, Judith A

Volltext

Autoantibody‐Positive Healthy Individuals Display Unique Immune Profiles That May Regulate Autoimmunity von Slight‐Webb, Samantha, Lu, Rufei, Ritterhouse, Lauren L., Munroe, Melissa E., Maecker, Holden T., Fathman, Charles G., Utz, Paul J., Merrill, Joan T., Guthridge, Joel M., James, Judith A.

Volltext

What Can Cognitive Science Do for People? von Prather, Richard W., Benitez, Viridiana L., Brooks, Lauren Kendall, Dancy, Christopher L., Dilworth‐Bart, Janean, Dutra, Natalia B., Faison, M. Omar, Figueroa, Megan, Holden, LaTasha R., Johnson, Cameron, Medrano, Josh, Miller‐Cotto, Dana, Matthews, Percival G., Manly, Jennifer J., Thomas, Ayanna K.

Volltext

The influence of face mask color on perceptions of African American and white men von Morris, Lauren A., Bazzini, Doris G., Holden, Christopher J., Lee, Savannah J.

Volltext

Landiolol and Organ Failure in Patients With Septic Shock: The STRESS-L Randomized Clinical Trial von Whitehouse, Tony, Hossain, Anower, Perkins, Gavin D, Gordon, Anthony C, Bion, Julian, Young, Duncan, McAuley, Danny, Singer, Mervyn, Lord, Janet, Gates, Simon, Veenith, Tonny, MacCallum, Niall S, Yeung, Joyce, Innes, Richard, Welters, Ingeborg, Boota, Nafisa, Skilton, Emma, Ghuman, Belinder, Hill, Maddy, Regan, Scott E, Mistry, Dipesh, Lall, Ranjit

Volltext