Dysregulated Iron Homeostasis as Common Disease Etiology and Promising Therapeutic Target von Holbein, Bruce E, Lehmann, Christian

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Iron should be restricted in acute infection von Scott, Cassidy R, Holbein, Bruce E, Lehmann, Christian D

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Iron Chelator DIBI Suppresses Formation of Ciprofloxacin-Induced Antibiotic Resistance in Staphylococcus aureus von Allan, David S., Holbein, Bruce E.

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Potential Mechanisms of Mucin-Enhanced Acinetobacter baumannii Virulence in the Mouse Model of Intraperitoneal Infection von Harris, Greg, Holbein, Bruce E, Zhou, Hongyan, Xu, H Howard, Chen, Wangxue

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Iron Chelation as a Potential Therapeutic Approach in Acute Lung Injury von Zhang, Xiyang, Zhou, Juan, Holbein, Bruce E, Lehmann, Christian

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Iron Sequestrant DIBI, a Potential Alternative for Nares Decolonization of Methicillin-Resistant Staphylococcus aureus, Is Anti-infective and Inhibitory for Mupirocin-Resistant Iso... von Allan, David S, Parquet, Maria Del Carmen, Savage, Kimberley A, Holbein, Bruce E

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Comparison of Treatment Effects of Different Iron Chelators in Experimental Models of Sepsis von Lehmann, Christian, Aali, Maral, Zhou, Juan, Holbein, Bruce

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Novel Iron-Chelator DIBI Inhibits Staphylococcus aureus Growth, Suppresses Experimental MRSA Infection in Mice and Enhances the Activities of Diverse Antibiotics in vitro von Parquet, Maria Del Carmen, Savage, Kimberley A, Allan, David S, Davidson, Ross J, Holbein, Bruce E

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Iron Withdrawal with DIBI, a Novel 3-Hydroxypyridin-4-One Chelator Iron-Binding Polymer, Attenuates Macrophage Inflammatory Responses von Ghassemi-Rad, Javad, Fernando, Wasundara, Holbein, Bruce E., Hoskin, David W.

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Anti-Inflammatory Effects of the Iron Chelator, DIBI, in Experimental Acute Lung Injury von Lehmann, Christian, Alizadeh-Tabrizi, Nazli, Hall, Stefan, Faridi, Sufyan, Euodia, Irene, Holbein, Bruce, Zhou, Juan, Chappe, Valerie

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Anti-inflammatory and anti-bacterial effects of iron chelation in experimental sepsis von Islam, Sufia, PhD, Jarosch, Stefan, DEAA, Zhou, Juan, MD, PhD, Parquet, Maria del Carmen, PhD, Toguri, James Thomas, BSc, Colp, Patricia, Holbein, Bruce E., PhD, Lehmann, Christian, MD, PhD, FRCPC

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Iron Restriction to Clinical Isolates of Candida albicans by the Novel Chelator DIBI Inhibits Growth and Increases Sensitivity to Azoles In Vitro and In Vivo in a Murine Model of E... von Savage, Kimberley A, Parquet, Maria del Carmen, Allan, David S, Davidson, Ross J, Holbein, Bruce E, Lilly, Elizabeth A, Fidel, Jr, Paul L

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Antibiotic-Resistant Acinetobacter baumannii Is Susceptible to the Novel Iron-Sequestering Anti-infective DIBI In Vitro and in Experimental Pneumonia in Mice von Parquet, Maria Del Carmen, Savage, Kimberley A, Allan, David S, Ang, M Trisha C, Chen, Wangxue, Logan, Susan M, Holbein, Bruce E

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Selective sensitivity of the gut microbiome to iron chelators in polybacterial abdominal sepsis von Dickson, Kayle, Liu, Simo, Zhou, Juan, Langille, Morgan, Holbein, Bruce E., Lehmann, Christian

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Iron-withdrawing anti-infectives for new host-directed therapies based on iron dependence, the Achilles’ heel of antibiotic-resistant microbes von Holbein, Bruce E., Ang, M. Trisha C., Allan, David S., Chen, Wangxue, Lehmann, Christian

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Enhanced Fe3+ binding through cooperativity of 3-hydroxypyridin-4-one groups within a linear co-polymer: wrapping effect leading to superior antimicrobial activity von Gumbau-Brisa, Roger, Ang, M. Trisha C., Holbein, Bruce E., Bierenstiel, Matthias

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Antimicrobial Activity of the Iron-Chelator, DIBI, against Multidrug-Resistant Canine Methicillin-Susceptible Staphylococcus pseudintermedius: A Preliminary Study of Four Clinical... von Nocera, Francesca Paola, Iovane, Giuseppe, De Martino, Luisa, Holbein, Bruce E.

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Iron chelation for the treatment of uveitis von Chen, Junru, Zhou, Juan, Kelly, Mel, Holbein, Bruce E, Lehmann, Christian

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DIBI, a novel 3-hydroxypyridin-4-one chelator iron-binding polymer, inhibits breast cancer cell growth and functions as a chemosensitizer by promoting S-phase DNA damage von Greenshields, Anna L., Power Coombs, Melanie R., Fernando, Wasundara, Holbein, Bruce E., Hoskin, David W.

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DIBI, a 3-hydroxypyridin-4-one chelator iron-binding polymer with enhanced antimicrobial activity von Ang, M. Trisha C, Gumbau-Brisa, Roger, Allan, David S, McDonald, Robert, Ferguson, Michael J, Holbein, Bruce E, Bierenstiel, Matthias

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