Massively parallel single-cell B-cell receptor sequencing enables rapid discovery of diverse antigen-reactive antibodies von Goldstein, Leonard D., Chen, Ying-Jiun J., Wu, Jia, Chaudhuri, Subhra, Hsiao, Yi-Chun, Schneider, Kellen, Hoi, Kam Hon, Lin, Zhonghua, Guerrero, Steve, Jaiswal, Bijay S., Stinson, Jeremy, Antony, Aju, Pahuja, Kanika Bajaj, Seshasayee, Dhaya, Modrusan, Zora, Hötzel, Isidro, Seshagiri, Somasekar

Volltext

Identification and characterization of the constituent human serum antibodies elicited by vaccination von Lavinder, Jason J., Wine, Yariv, Giesecke, Claudia, Ippolito, Gregory C., Horton, Andrew P., Lungu, Oana I., Hoi, Kam Hon, DeKosky, Brandon J., Murrin, Ellen M., Wirth, Megan M., Ellington, Andrew D., Dörner, Thomas, Marcotte, Edward M., Boutz, Daniel R., Georgiou, George

Volltext

Rapid identification of anti-idiotypic mAbs with high affinity and diverse epitopes by rabbit single B-cell sorting-culture and cloning technology von Lin, WeiYu, Liang, Wei-Ching, Nguy, Trung, Maia, Mauricio, Tyagi, Tulika, Chiu, Cecilia, Hoi, Kam Hon, Chen, Yongmei, Wu, Yan

Volltext

Monoclonal antibodies isolated without screening by analyzing the variable-gene repertoire of plasma cells von Georgiou, George, Reddy, Sai T, Ge, Xin, Miklos, Aleksandr E, Hughes, Randall A, Kang, Seung Hyun, Hoi, Kam Hon, Chrysostomou, Constantine, Hunicke-Smith, Scott P, Iverson, Brent L, Tucker, Philip W, Ellington, Andrew D

Volltext

Prediction of methionine oxidation risk in monoclonal antibodies using a machine learning method von Sankar, Kannan, Hoi, Kam Hon, Yin, Yizhou, Ramachandran, Prasanna, Andersen, Nisana, Hilderbrand, Amy, McDonald, Paul, Spiess, Christoph, Zhang, Qing

Volltext

Molecular deconvolution of the monoclonal antibodies that comprise the polyclonal serum response von Wine, Yariv, Boutz, Daniel R., Lavinder, Jason J., Miklos, Aleksandr E., Hughes, Randall A., Hoi, Kam Hon, Jung, Sang Taek, Horton, Andrew P., Murrin, Ellen M., Ellington, Andrew D., Marcotte, Edward M., Georgiou, George

Volltext

Systematic characterization and comparative analysis of the rabbit immunoglobulin repertoire von Lavinder, Jason J, Hoi, Kam Hon, Reddy, Sai T, Wine, Yariv, Georgiou, George

Volltext

Dynamics of heavy chain junctional length biases in antibody repertoires von Sankar, Kannan, Hoi, Kam Hon, Hötzel, Isidro

Volltext

Antibody repertoires in humanized NOD-scid-IL2Rγ(null) mice and human B cells reveals human-like diversification and tolerance checkpoints in the mouse von Ippolito, Gregory C, Hoi, Kam Hon, Reddy, Sai T, Carroll, Sean M, Ge, Xin, Rogosch, Tobias, Zemlin, Michael, Shultz, Leonard D, Ellington, Andrew D, Vandenberg, Carla L, Georgiou, George

Volltext

Differences in the composition of the human antibody repertoire by B cell subsets in the blood von Mroczek, Eva Szymanska, Ippolito, Gregory C, Rogosch, Tobias, Hoi, Kam Hon, Hwangpo, Tracy A, Brand, Marsha G, Zhuang, Yingxin, Liu, Cun Ren, Schneider, David A, Zemlin, Michael, Brown, Elizabeth E, Georgiou, George, Schroeder, Jr, Harry W

Volltext

Antibody interfaces revealed through structural mining von Yin, Yizhou, Romei, Matthew G., Sankar, Kannan, Pal, Lipika R., Hoi, Kam Hon, Yang, Yanli, Leonard, Brandon, De Leon Boenig, Gladys, Kumar, Nikit, Matsumoto, Marissa, Payandeh, Jian, Harris, Seth F., Moult, John, Lazar, Greg A.

Volltext

Antibody Repertoires in Humanized NOD-scid-IL2Rγnull Mice and Human B Cells Reveals Human-Like Diversification and Tolerance Checkpoints in the Mouse von Ippolito, Gregory C., Hoi, Kam Hon, Reddy, Sai T., Carroll, Sean M., Ge, Xin, Rogosch, Tobias, Zemlin, Michael, Shultz, Leonard D., Ellington, Andrew D., VanDenBerg, Carla L., Georgiou, George

Volltext

Molecular-level analysis of the serum antibody repertoire in young adults before and after seasonal influenza vaccination von Lee, Jiwon, Boutz, Daniel R, Chromikova, Veronika, Joyce, M Gordon, Vollmers, Christopher, Leung, Kwanyee, Horton, Andrew P, DeKosky, Brandon J, Lee, Chang-Han, Lavinder, Jason J, Murrin, Ellen M, Chrysostomou, Constantine, Hoi, Kam Hon, Tsybovsky, Yaroslav, Thomas, Paul V, Druz, Aliaksandr, Zhang, Baoshan, Zhang, Yi, Wang, Lingshu, Kong, Wing-Pui, Park, Daechan, Popova, Lyubov I, Dekker, Cornelia L, Davis, Mark M, Carter, Chalise E, Ross, Ted M, Ellington, Andrew D, Wilson, Patrick C, Marcotte, Edward M, Mascola, John R, Ippolito, Gregory C, Krammer, Florian, Quake, Stephen R, Kwong, Peter D, Georgiou, George

Volltext

Antibody homotypic interactions are encoded by germline light chain complementarity determining region 2 von Leonard, Brandon, Sankar, Kannan, Romei, Matthew G, Tse, Margaret J, Do, Nina, Yang, Yanli, Matochko, Wadim L, Bevers, Jack, Bollineni, Sundeep, Mukhyala, Kiran, Hoi, Kam Hon, Lazar, Greg A

Volltext

Antibody homotypic interactions are encoded by germline light chain complementarity determining region 2 von Leonard, Brandon, Sankar, Kannan, Romei, Matthew G, Tse, Margaret J, Do, Nina, Yang, Yanli, Matochko, Wadim L, Bevers, Jack, Bollineni, Sundeep, Mukhyala, Kiran, Hoi, Kam Hon, Lazar, Greg A

Volltext

Profiling Protease Specificity: Combining Yeast ER Sequestration Screening (YESS) with Next Generation Sequencing von Li, Qing, Yi, Li, Hoi, Kam Hon, Marek, Peter, Georgiou, George, Iverson, Brent L

Volltext

Barcoded sequencing workflow for high throughput digitization of hybridoma antibody variable domain sequences von Chen, Yongmei, Kim, Si Hyun, Shang, Yonglei, Guillory, Joseph, Stinson, Jeremy, Zhang, Qing, Hötzel, Isidro, Hoi, Kam Hon

Volltext

Activation-Induced Cytidine Deaminase Impacts the Primary Antibody Repertoire in Naive Mice von Bao, Katherine, Zhang, Juan, Scherl, Alexis, Ziai, James, Hadadianpour, Azi, Xu, Daqi, Dela Cruz, Christopher, Liu, John, Liang, Yuxin, Tam, Lucinda, Corzo, Cesar A, Roose-Girma, Merone, Warming, Soren, Modrusan, Zora, Lee, Wyne P, Hoi, Kam Hon, Zarrin, Ali A

Volltext

Supplementation of Nucleosides During Selection can Reduce Sequence Variant Levels in CHO Cells Using GS/MSX Selection System von Tang, Danming, Lam, Cynthia, Louie, Salina, Hoi, Kam Hon, Shaw, David, Yim, Mandy, Snedecor, Brad, Misaghi, Shahram

Volltext

Immunoglobulin analysis tool: a novel tool for the analysis of human and mouse heavy and light chain transcripts von Rogosch, Tobias, Kerzel, Sebastian, Hoi, Kam Hon, Zhang, Zhixin, Maier, Rolf F, Ippolito, Gregory C, Zemlin, Michael

Volltext