B7-CD28 co-stimulation modulates central tolerance via thymic clonal deletion and Treg generation through distinct mechanisms von Watanabe, Masashi, Lu, Ying, Breen, Michael, Hodes, Richard J.

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Downmodulation of Tumor Suppressor p53 by T Cell Receptor Signaling Is Critical for Antigen-Specific CD4+ T Cell Responses von Watanabe, Masashi, Moon, Kyung Duk, Vacchio, Melanie S., Hathcock, Karen S., Hodes, Richard J.

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Disease drivers of aging von Hodes, Richard J., Sierra, Felipe, Austad, Steven N., Epel, Elissa, Neigh, Gretchen N., Erlandson, Kristine M., Schafer, Marissa J., LeBrasseur, Nathan K., Wiley, Christopher, Campisi, Judith, Sehl, Mary E., Scalia, Rosario, Eguchi, Satoru, Kasinath, Balakuntalam S., Halter, Jeffrey B., Cohen, Harvey Jay, Demark-Wahnefried, Wendy, Ahles, Tim A., Barzilai, Nir, Hurria, Arti, Hunt, Peter W.

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Co-stimulatory function in primary germinal center responses: CD40 and B7 are required on distinct antigen-presenting cells von Watanabe, Masashi, Fujihara, Chiharu, Radtke, Andrea J, Chiang, Y Jeffrey, Bhatia, Sumeena, Germain, Ronald N, Hodes, Richard J

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Telomere Shortening, Inflammatory Cytokines, and Anti-Cytomegalovirus Antibody Follow Distinct Age-Associated Trajectories in Humans von Lustig, Ana, Liu, Hans B, Metter, E Jeffrey, An, Yang, Swaby, Melissa A, Elango, Palchamy, Ferrucci, Luigi, Hodes, Richard J, Weng, Nan-Ping

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Thymic medullary epithelium and thymocyte self-tolerance require cooperation between CD28-CD80/86 and CD40-CD40L costimulatory pathways von Williams, Joy A, Zhang, Jingjing, Jeon, Hyein, Nitta, Takeshi, Ohigashi, Izumi, Klug, David, Kruhlak, Michael J, Choudhury, Baishakhi, Sharrow, Susan O, Granger, Larry, Adams, Anthony, Eckhaus, Michael A, Jenkinson, S Rhiannon, Richie, Ellen R, Gress, Ronald E, Takahama, Yousuke, Hodes, Richard J

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Rapid Scaling Up of Covid-19 Diagnostic Testing in the United States — The NIH RADx Initiative von Tromberg, Bruce J, Schwetz, Tara A, Pérez-Stable, Eliseo J, Hodes, Richard J, Woychik, Richard P, Bright, Rick A, Fleurence, Rachael L, Collins, Francis S

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Regulation of T cell development by c-Cbl: essential role of Lck von Chiang, Y Jeffrey, Hodes, Richard J

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Telomere length is inherited with resetting of the telomere set-point von Chiang, Y. Jeffrey, Calado, Rodrigo T, Hathcock, Karen S, Lansdorp, Peter M, Young, Neal S, Hodes, Richard J

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A Blueprint for Characterizing Senescence von Roy, Ananda L., Sierra, Felipe, Howcroft, Kevin, Singer, Dinah S., Sharpless, Norman, Hodes, Richard J., Wilder, Elizabeth L., Anderson, James M.

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Both telomeric and non-telomeric DNA damage are determinants of mammalian cellular senescence von Nakamura, Asako J, Chiang, Y Jeffrey, Hathcock, Karen S, Horikawa, Izumi, Sedelnikova, Olga A, Hodes, Richard J, Bonner, William M

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TRAF6 and TRAF2/3 Binding Motifs in CD40 Differentially Regulate B Cell Function in T-Dependent Antibody Responses and Dendritic Cell Function in Experimental Autoimmune Encephalom... von Lu, Ying, Chiang, Jeffrey, Zhang, Ray, Roche, Paul A, Hodes, Richard J

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Cbl enforces Vav1 dependence and a restricted pathway of T cell development von Chiang, Jeffrey, Hodes, Richard J

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ATM influences the efficiency of TCRβ rearrangement, subsequent TCRβ-dependent T cell development, and generation of the pre-selection TCRβ CDR3 repertoire von Hathcock, Karen S, Bowen, Steven, Livak, Ferenc, Hodes, Richard J

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TRAF3 enforces the requirement for T cell cross-talk in thymic medullary epithelial development von Jenkinson, S. Rhiannon, Williams, Joy A., Jeon, Hyein, Zhang, Jingjing, Nitta, Takeshi, Ohigashi, Izumi, Kruhlak, Michael, Zuklys, Saulius, Sharrow, Susan, Adams, Anthony, Granger, Larry, Choi, Yongwon, Siebenlist, Ulrich, Bishop, Gail A., Hollander, Georg A., Takahama, Yousuke, Hodes, Richard J.

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ATM Deficiency Impairs Thymocyte Maturation Because of Defective Resolution of T Cell Receptor α Locus Coding End Breaks von Vacchio, Melanie S., Olaru, Alexandru, Livak, Ferenc, Hodes, Richard J.

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Antigen-presenting T cells provide critical B7 co-stimulation for thymic iNKT cell development via CD28-dependent trogocytosis von Watanabe, Masashi, Celli, Sofia, Alkhaleel, Farrah A., Hodes, Richard J.

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National Institute on Aging at Middle Age-Its Past, Present, and Future von Nagy, Catherine L., Bernard, Marie A., Hodes, Richard J.

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Decreased glucocerebrosidase activity in Gaucher disease parallels quantitative enzyme loss due to abnormal interaction with TCP1 and c-Cbl von Lu, Jie, Chiang, Jeffrey, Iyer, Rajiv R., Thompson, Eli, Kaneski, Christine R., Xu, David S., Yang, Chunzhang, Chen, Masako, Hodes, Richard J., Lonser, Russell R., Brady, Roscoe O., Zhuang, Zhengping

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The NIH Blueprint for Neuroscience Research Seeks Community Input on Future Neuroscience Investments von Mott, Meghan C, Austin, Christopher P, Bianchi, Diana W, Cashion, Ann K, Gordon, Joshua A, Heemskerk, Jill E, Hodes, Richard J, Koob, George F, Riley, William T, Sieving, Paul A, Shurtleff, David, Somerman, Martha J, Volkow, Nora D, Anderson, Kathleen C, Owens, David F, Koroshetz, Walter J

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