NOTUM from Apc-mutant cells biases clonal competition to initiate cancer von Flanagan, Dustin J., Pentinmikko, Nalle, Luopajärvi, Kalle, Willis, Nicky J., Gilroy, Kathryn, Raven, Alexander P., Mcgarry, Lynn, Englund, Johanna I., Webb, Anna T., Scharaw, Sandra, Nasreddin, Nadia, Hodder, Michael C., Ridgway, Rachel A., Minnee, Emma, Sphyris, Nathalie, Gilchrist, Ella, Najumudeen, Arafath K., Romagnolo, Beatrice, Perret, Christine, Williams, Ann C., Clevers, Hans, Nummela, Pirjo, Lähde, Marianne, Alitalo, Kari, Hietakangas, Ville, Hedley, Ann, Clark, William, Nixon, Colin, Kirschner, Kristina, Jones, E. Yvonne, Ristimäki, Ari, Leedham, Simon J., Fish, Paul V., Vincent, Jean-Paul, Katajisto, Pekka, Sansom, Owen J.

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Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesis von Leach, JDG, Vlahov, N, Tsantoulis, P, Ridgway, RA, Flanagan, DJ, Gilroy, K, Sphyris, N, Vázquez, EG, Vincent, DF, Faller, WJ, Hodder, MC, Raven, A, Fey, S, Najumudeen, AK, Strathdee, D, Nixon, C, Hughes, M, Clark, W, Shaw, R, S:CORT consortium, van Hooff, SR, Huels, DJ, Medema, JP, Barry, ST, Frame, MC, Unciti-Broceta, A, Leedham, SJ, Inman, GJ, Jackstadt, R, Thompson, BJ, Campbell, AD, Tejpar, S, Sansom, OJ

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NOTUM from Apc-mutant cells biases clonal competition to initiate cancer von Flanagan, DJ, Pentinmikko, N, Luopajärvi, K, Willis, NJ, Gilroy, K, Raven, AP, Mcgarry, L, Englund, J, Webb, AT, Scharaw, S, Nasreddin, N, Hodder, MC, Ridgway, RA, Minnee, E, Sphyris, N, Gilchrist, E, Najumudeen, AK, Romagnolo, B, Perret, C, Williams, AC, Clevers, H, Nummela, P, Lähde, M, Alitalo, K, Hietakangas, V, Hedley, A, Clark, W, Nixon, C, Kirschner, K, Jones, EY, Ristimäki, A, Leedham, SJ, Fish, P, Vincent, J-P, Katajisto, P, Sansom, OJ

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Living systematic review: 1. Introduction—the why, what, when, and how von Synnot, Anneliese, Turner, Tari, Simmonds, Mark, Akl, Elie A., McDonald, Steve, Salanti, Georgia, Meerpohl, Joerg, MacLehose, Harriet, Hilton, John, Tovey, David, Shemilt, Ian, Hilton, John, Akl, Elie, Pestridge, Charlotte, Horsley, Tanya, Armstrong, Rebecca, Plovnick, Robert, Arno, Anneliese, Au, Agnes, Johnston, Renea, Rada, Gabriel, Bagg, Matthew, Jones, Arwel, Ravaud, Philippe, Boden, Catherine, Kahale, Lara, Richter, Bernt, Boisvert, Isabelle, Keshavarz, Homa, Ryan, Rebecca, Brandt, Linn, Kolakowsky-Hayner, Stephanie A., Salama, Dina, Brazinova, Alexandra, Nagraj, Sumanth Kumbargere, Salanti, Georgia, Buchbinder, Rachelle, Lasserson, Toby, Santaguida, Lina, Champion, Chris, Lawrence, Rebecca, Schünemann, Holger J., Charidimou, Andreas, Leucht, Stefan, Shemilt, Ian, Low, Nicola, Sherifali, Diana, Churchill, Rachel, MacLehose, Harriet, Simmonds, Mark, Cossi, Marie-Joelle, Counotte, Michel, Marshall, Iain, Soares-Weiser, Karla, Craigie, Samantha, Marshall, Rachel, Srikanth, Velandai, Martin, Nicole, Martínez García, Laura, Danko, Kristen, Taylor, Mark, Donoghue, Emma, Maxwell, Lara J., Thayer, Kris, Dressler, Corinna, McAuley, James, Thomas, James, Tritton, Roger, Elliott, Julian, McKenzie, Joanne, Tsafnat, Guy, Meerpohl, Joerg, Tugwell, Peter, Merner, Bronwen, Featherstone, Robin, Mondello, Stefania, Foxlee, Ruth, Morley, Richard, van Valkenhoef, Gert, Munafo, Marcus, Gerrity, Martha, Munn, Zachary, Wallace, Byron, Glasziou, Paul, Murano, Melissa, Wallace, Sheila A., Newman, Kristine, Watts, Chris, Nieuwlaat, Robby, Gurusamy, Kurinchi, Nikolakopoulou, Adriani, Weigl, Aaron, Hartling, Lisa, Wiercioch, Wojtek, Wolfenden, Luke, Pahwa, Manisha, Yepes Nuñez, Juan José, Yost, Jennifer, Hill, Sophie, Pearson, Leslea

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Living systematic reviews: 4. Living guideline recommendations von Akl, Elie A., Meerpohl, Joerg J., Elliott, Julian, Kahale, Lara A., Hilton, John, Perron, Caroline, Akl, Elie, Hodder, Rebecca, Pestridge, Charlotte, Albrecht, Lauren, Horsley, Tanya, Platt, Joanne, Nguyen, Phi Hung, Plovnick, Robert, Arno, Anneliese, Ivers, Noah, Au, Agnes, Jones, Arwel, Ravaud, Philippe, Boden, Catherine, Kahale, Lara, Richter, Bernt, Boisvert, Isabelle, Keshavarz, Homa, Brandt, Linn, Kolakowsky-Hayner, Stephanie A., Salama, Dina, Brazinova, Alexandra, Nagraj, Sumanth Kumbargere, Salanti, Georgia, Lasserson, Toby, Santaguida, Lina, Champion, Chris, Chandler, Jackie, Les, Zbigniew, Schünemann, Holger J., Charidimou, Andreas, Leucht, Stefan, Shemilt, Ian, Low, Nicola, Churchill, Rachel, Maas, Andrew, Siemieniuk, Reed, MacLehose, Harriet, Simmonds, Mark, Cossi, Marie-Joelle, Skoetz, Nicole, Marshall, Iain, Soares-Weiser, Karla, Craigie, Samantha, Marshall, Rachel, Srikanth, Velandai, Dahm, Philipp, Martin, Nicole, Synnot, Anneliese, Danko, Kristen, Mavergames, Chris, Taylor, Mark, Donoghue, Emma, Maxwell, Lara J., Thayer, Kris, Dressler, Corinna, McAuley, James, Thomas, James, Egan, Cathy, Elliott, Julian, Meerpohl, Joerg, Tugwell, Peter, Etxeandia, Itziar, Featherstone, Robin, Mondello, Stefania, Turner, Tari, Foxlee, Ruth, van Valkenhoef, Gert, Garner, Paul, Munafo, Marcus, Vandvik, Per, Gerrity, Martha, Wallace, Byron, Murano, Melissa, Wallace, Sheila A., Newman, Kristine, Watts, Chris, Grimshaw, Jeremy, Weeks, Laura, Gurusamy, Kurinchi, Nikolakopoulou, Adriani, Weigl, Aaron, Noel-Storr, Anna, Wells, George, Hartling, Lisa, O'Connor, Annette, Wiercioch, Wojtek, Hayden, Jill, Page, Matthew, Wolfenden, Luke, Helfand, Mark, Pardo, Jordi Pardo, Yost, Jennifer, Hill, Sophie

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Dolutegravir versus raltegravir in antiretroviral-experienced, integrase-inhibitor-naive adults with HIV: week 48 results from the randomised, double-blind, non-inferiority SAILING... von Cahn, Pedro, Dr, Pozniak, Anton L, MD, Mingrone, Horacio, MD, Shuldyakov, Andrey, MD, Brites, Carlos, MD, Andrade-Villanueva, Jaime F, MD, Richmond, Gary, MD, Buendia, Carlos Beltran, MD, Fourie, Jan, MD, Ramgopal, Moti, MD, Hagins, Debbie, MD, Felizarta, Franco, MD, Madruga, Jose, MD, Reuter, Tania, MD, Newman, Tamara, MD, Small, Catherine B, MD, Lombaard, John, MD, Grinsztejn, Beatriz, MD, Dorey, David, MMath, Underwood, Mark, PhD, Griffith, Sandy, PharmD, Min, Sherene, MD

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High-Frequency Oscillation in Early Acute Respiratory Distress Syndrome von Ferguson, Niall D, Cook, Deborah J, Guyatt, Gordon H, Mehta, Sangeeta, Hand, Lori, Austin, Peggy, Zhou, Qi, Matte, Andrea, Walter, Stephen D, Lamontagne, Francois, Granton, John T, Arabi, Yaseen M, Arroliga, Alejandro C, Stewart, Thomas E, Slutsky, Arthur S, Meade, Maureen O

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Effectiveness of embedding a specialist preventive care clinician in a community mental health service in increasing preventive care provision: A randomised controlled trial von Fehily, Caitlin MC, Bartlem, Kate M, Wiggers, John H, Wye, Paula M, Clancy, Richard V, Castle, David J, Wilson, Andrew, Rissel, Chris E, Wutzke, Sonia, Hodder, Rebecca K, Colyvas, Kim, Murphy, Fionna, Bowman, Jenny A

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The Septic Shock 3.0 Definition and Trials: A Vasopressin and Septic Shock Trial Experience von Russell, James A., Lee, Terry, Singer, Joel, Boyd, John H., Walley, Keith R.

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Seven-Year Surveillance of North American Pediatric Group A Streptococcal Pharyngitis Isolates von Shulman, Stanford T., Tanz, Robert R, Dale, James B., Beall, Bernard, Kabat, William, Kabat, Kathleen, Cederlund, Emily, Patel, Devendra, Rippe, Jason, Li, Zhongya, Sakota, Varja

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Admission of the very elderly to the intensive care unit: Family members’ perspectives on clinical decision-making from a multicenter cohort study von Heyland, Daren K, Dodek, Peter, Mehta, Sangeeta, Cook, Deborah, Garland, Allan, Stelfox, Henry T, Bagshaw, Sean M, Kutsogiannis, Demetrios J, Burns, Karen, Muscedere, John, Turgeon, Alexis F, Fowler, Rob, Jiang, Xuran, Day, Andrew G

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Randomized trial of combination versus monotherapy for the empiric treatment of suspected ventilator-associated pneumonia von Heyland, Daren K, Dodek, Peter, Muscedere, John, Day, Andrew, Cook, Deborah

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Development of a patient-administered selfassessment tool (SATp) for follow-up of colorectal cancer patients in general practice von Ngune, Irene, Jiwa, Moyez, Manus, Alexandra Mc, Hughes, Jeff, Parsons, Richard, Hodder, Rupert, Entriken, Fiona

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Mr Emerson’s Revolution von Brown, Steven, Cole, Phyllis, Gougeon, Len, Hodder, Alan, McClure Mudge, Jean, Mott, Wesley T, Robinson, David M, Soressi, Beniamino, Stauffer, John

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A multifactor model for international plant location and financing under uncertainty von Hodder, James E., Dincer, M.Cemal

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Theophylline for Irreversible Chronic Airflow Limitation von Mahon, Jeffrey L., Laupacis, Andreas, Hodder, Richard V., Mc Kim, Douglas A., Paterson, Nigel A.M., Wood, Thomas E., Donner, Allan

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