Dissecting mechanisms of resistance to targeted drug combination therapy in human colorectal cancer von Clarke, Paul A., Roe, Toby, Swabey, Kate, Hobbs, Steve M., McAndrew, Craig, Tomlin, Kathy, Westwood, Isaac, Burke, Rosemary, van Montfort, Robert, Workman, Paul

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JAK2V617F leads to intrinsic changes in platelet formation and reactivity in a knock-in mouse model of essential thrombocythemia von Hobbs, Catherine M., Manning, Harriet, Bennett, Cavan, Vasquez, Louella, Severin, Sonia, Brain, Lauren, Mazharian, Alexandra, Guerrero, Jose A., Li, Juan, Soranzo, Nicole, Green, Anthony R., Watson, Steve P., Ghevaert, Cedric

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Endocrine and haemodynamic changes in resistant hypertension, and blood pressure responses to spironolactone or amiloride: the PATHWAY-2 mechanisms substudies von Williams, Bryan, MacDonald, Thomas M, Morant, Steve V, Webb, David J, Sever, Peter, McInnes, Gordon T, Ford, Ian, Cruickshank, J Kennedy, Caulfield, Mark J, Padmanabhan, Sandosh, Mackenzie, Isla S, Salsbury, Jackie, Brown, Morris J, Balakrishnan, K, Burton, T, Cannon, J, Collier, D, Coughlan, C, D'Souza, R, Enobakhare, E, Findlay, E, Gardiner-Hill, C, Gupta, P, Helmy, J, Helmy, C, Hobbs, L, Hobbs, R, Hood, S, Iles, R, Kean, S, Kwok, S, Lacy, P, MacIntyre, I, Mackay, J, Markandu, N, Martin, U, McCallum, L, McCann, G, McGinnis, A, Melville, V, Muir, S, Myint, KS, Nazir, S, Palmer, J, Papworth, R, Rutkowski, K, Saxena, M, Schumann, A, Soran, H, Stanley, A, Thom, S, Webb, A, White, C, Wilson, R, Zak, A

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A genome sequencing system for universal newborn screening, diagnosis, and precision medicine for severe genetic diseases von Kingsmore, Stephen F., Smith, Laurie D., Kunard, Chris M., Bainbridge, Matthew, Batalov, Sergey, Benson, Wendy, Blincow, Eric, Caylor, Sara, Chambers, Christina, Del Angel, Guillermo, Dimmock, David P., Ding, Yan, Ellsworth, Katarzyna, Feigenbaum, Annette, Frise, Erwin, Green, Robert C., Guidugli, Lucia, Hall, Kevin P., Hansen, Christian, Hobbs, Charlotte A., Kahn, Scott D., Kiel, Mark, Van Der Kraan, Lucita, Krilow, Chad, Kwon, Yong H., Madhavrao, Lakshminarasimha, Le, Jennie, Lefebvre, Sebastien, Mardach, Rebecca, Mowrey, William R., Oh, Danny, Owen, Mallory J., Powley, George, Scharer, Gunter, Shelnutt, Seth, Tokita, Mari, Mehtalia, Shyamal S., Oriol, Albert, Papadopoulos, Stavros, Perry, James, Rosales, Edwin, Sanford, Erica, Schwartz, Steve, Tran, Duke, Reese, Martin G., Wright, Meredith, Veeraraghavan, Narayanan, Wigby, Kristen, Willis, Mary J., Wolen, Aaron R., Defay, Thomas

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Reconstructing epilimnetic total phosphorus using diatoms: statistical and ecological constraints von Juggins, Steve, Anderson, N. John, Hobbs, Joy M. Ramstack, Heathcote, Adam J

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Dual Targeting of ErbB2 and MUC1 in Breast Cancer Using Chimeric Antigen Receptors Engineered to Provide Complementary Signaling von Wilkie, Scott, van Schalkwyk, May C. I., Hobbs, Steve, Davies, David M., van der Stegen, Sjoukje J. C., Pereira, Ana C. Parente, Burbridge, Sophie E., Box, Carol, Eccles, Suzanne A., Maher, John

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Effect of amiloride, or amiloride plus hydrochlorothiazide, versus hydrochlorothiazide on glucose tolerance and blood pressure (PATHWAY-3): a parallel-group, double-blind randomise... von Brown, Morris J, Prof, Williams, Bryan, Prof, Morant, Steve V, PhD, Webb, David J, Prof, Caulfield, Mark J, Prof, Cruickshank, J Kennedy, Prof, Ford, Ian, Prof, McInnes, Gordon, Prof, Sever, Peter, Prof, Salsbury, Jackie, RGN, Mackenzie, Isla S, FRCP, Padmanabhan, Sandosh, FRCP, MacDonald, Thomas M, Prof

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Aboriginal to non-Aboriginal differentials in 2-year outcomes following non-fatal first-ever acute MI persist after adjustment for comorbidity von Katzenellenbogen, Judith M, Sanfilippo, Frank M, Hobbs, Michael ST, Briffa, Tom G, Ridout, Steve C, Knuiman, Matthew W, Dimer, Lyn, Taylor, Kate P, Thompson, Peter L, Thompson, Sandra C

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Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease von Friedlander, Robert M, Chen, Minghua, Ona, Victor O, Li, Mingwei, Ferrante, Robert J, Fink, Klaus B, Zhu, Shan, Bian, Jie, Guo, Lei, Farrell, Laurie A, Hersch, Steve M, Hobbs, Wendy, Vonsattel, Jean-Paul, Cha, Jang-Ho J

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Longitudinal head-to-head comparison of 11C-PiB and 18F-florbetapir PET in a Phase 2/3 clinical trial of anti-amyloid-β monoclonal antibodies in dominantly inherited Alzheimer’s di... von Chen, Charles D., McCullough, Austin, Gordon, Brian, Joseph-Mathurin, Nelly, Flores, Shaney, McKay, Nicole S., Hobbs, Diana A., Hornbeck, Russ, Fagan, Anne M., Cruchaga, Carlos, Goate, Alison M., Perrin, Richard J., Wang, Guoqiao, Li, Yan, Shi, Xinyu, Xiong, Chengjie, Pontecorvo, Michael J., Klein, Gregory, Su, Yi, Klunk, William E., Jack, Clifford, Koeppe, Robert, Snider, B. Joy, Berman, Sarah B., Roberson, Erik D., Brosch, Jared, Surti, Ghulam, Jiménez-Velázquez, Ivonne Z., Galasko, Douglas, Honig, Lawrence S., Brooks, William S., Clarnette, Roger, Wallon, David, Dubois, Bruno, Pariente, Jérémie, Pasquier, Florence, Sanchez-Valle, Raquel, Shcherbinin, Sergey, Higgins, Ixavier, Tunali, Ilke, Masters, Colin L., van Dyck, Christopher H., Masellis, Mario, Hsiung, Robin, Gauthier, Serge, Salloway, Steve, Clifford, David B., Mills, Susan, Supnet-Bell, Charlene, McDade, Eric, Bateman, Randall J., Benzinger, Tammie L. S.

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Combination Therapy Is Superior to Sequential Monotherapy for the Initial Treatment of Hypertension: A Double‐Blind Randomized Controlled Trial von MacDonald, Thomas M., Williams, Bryan, Webb, David J., Morant, Steve, Caulfield, Mark, Cruickshank, J. Kennedy, Ford, Ian, Sever, Peter, Mackenzie, Isla S., Padmanabhan, Sandosh, McCann, Gerald P., Salsbury, Jackie, McInnes, Gordon, Brown, Morris J.

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Incidence of and Case Fatality Following Acute Myocardial Infarction in Aboriginal and Non-Aboriginal Western Australians (2000–2004): A Linked Data Study von Katzenellenbogen, Judith M., PhD, Sanfilippo, Frank M., PhD, Hobbs, Michael S.T., PhD, Briffa, Tom G., PhD, Ridout, Steve C., BSc, Knuiman, Matthew W., PhD, Dimer, Lyn, EN, Taylor, Kate P., MIH, Thompson, Peter L., PhD, Thompson, Sandra C., PhD

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Response to Grosse et al von Kingsmore, Stephen F, Smith, Laurie D, Kunard, Chris M, Bainbridge, Matthew, Batalov, Sergey, Benson, Wendy, Blincow, Eric, Caylor, Sara, Chambers, Christina, Del Angel, Guillermo, Dimmock, David P, Ding, Yan, Ellsworth, Katarzyna, Feigenbaum, Annette, Frise, Erwin, Green, Robert C, Guidugli, Lucia, Hall, Kevin P, Hansen, Christian, Hobbs, Charlotte A, Kahn, Scott D, Kiel, Mark, Van Der Kraan, Lucita, Krilow, Chad, Kwon, Yong H, Madhavrao, Lakshminarasimha, Le, Jennie, Lefebvre, Sebastien, Mardach, Rebecca, Mowrey, William R, Oh, Danny, Owen, Mallory J, Powley, George, Scharer, Gunter, Shelnutt, Seth, Tokita, Mari, Mehtalia, Shyamal S, Oriol, Albert, Papadopoulos, Stavros, Perry, James, Rosales, Edwin, Sanford, Erica, Schwartz, Steve, Tran, Duke, Reese, Martin G, Wright, Meredith, Veeraraghavan, Narayanan, Wigby, Kristen, Willis, Mary J, Wolen, Aaron R, Defay, Thomas

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The effect of aortic morphology on peri-operative mortality of ruptured abdominal aortic aneurysm von Anjum, A., Thompson, L., Azhar, B., Hughes, C., Karthikesalingam, A., Ashleigh, R., Thompson, M.M., Cheshire, Nicholas J., Boyle, Jonathan R., Serracino-Inglott, Ferdinand, Vince Smyth, J., Thompson, Matt M., Hinchliffe, Robert J., Bell, Rachel, Wilson, Noel, Bown, Matt, Dennis, Martin, Davis, Meryl, Ashleigh, Ray, Howell, Simon, Wyatt, Michael G., Valenti, Domenico, Bachoo, Paul, Walker, Paul, MacSweeney, Shane, Davies, Jonathan N., Rittoo, Dynesh, Parvin, Simon D., Yusuf, Waquar, Nice, Colin, Chetter, Ian, Howard, Adam, Chong, Patrick, Bhat, Raj, McLain, David, Gordon, Andrew, Lane, Ian, Hobbs, Simon, Pillay, Woolagasen, Rowlands, Timothy, El-Tahir, Amin, Asquith, John, Cavanagh, Steve, Forbes, Thomas L., Awopetu, Ayoola, Baker, Sara, Bourke, Patricia, Brady, Claire, Brown, Joanne, Bryce, Jennie, Bufton, Christine, Chance, Tina, Chrisopoulou, Angela, Cockell, Marie, Croucher, Andrea, Curran, Gail, Dabee, Leela, Dewhirst, Nikki, Evans, Jo, Gibson, Andy, Gorst, Siobhan, Gough, Moira, Graves, Lynne, Griffin, Michelle, Hatfield, Josie, Hogg, Florence, Howard, Susannah, Hughes, Thomas, James, Alex, Metcalfe, David, Lapworth, Michelle, Massey, Ian, Mohalhal, Awad, Novick, Teresa, Owen, Gareth, Parr, Noala, Pintar, David, Smith, Tom, Spencer, Sarah, Thomson, Claire, Thunder, Orla, Wallace, Tom, Ward, Sue, Wealleans, Vera, Wilson, Lesley, Woods, Janet, Zachariah, Manu, Zheng, Ting, Powell, Janet T., Sweeting, Michael J., Thompson, Matthew M., Greenhalgh, Roger M., Thompson, Simon G., Ulug, Pinar

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Evaluation of variables influencing success and complication rates in canine total hip replacement: results from the British Veterinary Orthopaedic Association Canine Hip Registry... von Henderson, Elisabeth R., Wills, Andrew, Torrington, Andrew M., Moores, Andy P., Thomson, David, Arthurs, Gareth, Brown, Gordon, Denny, Hamish R., Scott, Harry W., MacQueen, Ian, Dunne, James, Onyett, Jeremy, Walker, John D., Prior, John, Owen, Martin R., Burton, Neil, Whitelock, Richard, Girling, Sarah, Morrison, Shane, Gilbert, Simon, Langley-Hobbs, Sorrel J., Gemmill, Toby J., Störk, Christoph K., Bright, Steve, Comerford, Eithne, Pettitt, Rob, Macdonald, Nick, Innes, John F.

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Testing the generality of above-ground biomass allometry across plant functional types at the continent scale von Paul, Keryn I., Roxburgh, Stephen H., Chave, Jerome, England, Jacqueline R., Zerihun, Ayalsew, Specht, Alison, Lewis, Tom, Bennett, Lauren T., Baker, Thomas G., Adams, Mark A., Huxtable, Dan, Montagu, Kelvin D., Falster, Daniel S., Feller, Mike, Sochacki, Stan, Ritson, Peter, Bastin, Gary, Bartle, John, Wildy, Dan, Hobbs, Trevor, Larmour, John, Waterworth, Rob, Stewart, Hugh T.L., Jonson, Justin, Forrester, David I., Applegate, Grahame, Mendham, Daniel, Bradford, Matt, O'Grady, Anthony, Green, Daryl, Sudmeyer, Rob, Rance, Stan J., Turner, John, Barton, Craig, Wenk, Elizabeth H., Grove, Tim, Attiwill, Peter M., Pinkard, Elizabeth, Butler, Don, Brooksbank, Kim, Spencer, Beren, Snowdon, Peter, O'Brien, Nick, Battaglia, Michael, Cameron, David M, Hamilton, Steve, McAuthur, Geoff, Sinclair, Jenny

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Endovascular strategy or open repair for ruptured abdominal aortic aneurysm: one-year outcomes from the IMPROVE randomized trial von Grieve, Richard, Sweeting, Michael J, Thompson, Simon G, Gomes, Manuel, Powell, Janet T, Ashleigh, Ray, Greenhalgh, Roger M, Hinchliffe, Robert J, Thompson, Matt M, Ulug, Pinar

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Intracranial neurenteric cyst mimicking an ependymoma: imaging features, pathologic correlation and review of literature von Nelson, Steve M, Mathis, Derek A, Hobbs, Joseph K, Timpone, Vincent M

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Variable effects of prevalence correction of population denominators on differentials in myocardial infarction incidence: a record linkage study in Aboriginal and non-Aboriginal We... von Katzenellenbogen, Judith M, Sanfilippo, Frank M, Hobbs, Michael S.T, Briffa, Tom G, Ridout, Steve C, Knuiman, Matthew W, Dimer, Lyn, Taylor, Kate P, Thompson, Peter L, Thompson, Sandra C

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CSF proteomics identifies early changes in autosomal dominant Alzheimer’s disease von Timsina, Jigyasha, Heo, Gyujin, Beric, Aleksandra, Yang, Chengran, Wang, Yueyao, Western, Daniel, Do, Anh, Liu, Haiyan, Gordon, Brian, Llibre-Guerra, Jorge J., Joseph-Mathurin, Nelly, Perrin, Richard J., Maschi, Dario, Wyss-Coray, Tony, Pastor, Pau, Surace, Ezequiel I., Johnson, Erik C.B., Levin, Johannes, Allegri, Ricardo Francisco, Seyfried, Nicholas, Day, Gregg S., Tarawneh, Rawan, Morris, John C., Bateman, Randall J., Goate, Alison, Noble, James M., Voglein, Jonathan, Allegri, Ricardo, Mendez, Patricio Chrem, Berman, Sarah B., Ikonomovic, Snezana, Nadkarni, Neelesh, Lopera, Francisco, Ramirez, Laura, Baena, Ana, Londono, Natalia, Mathias Jucker, Sonia Moreno, Laske, Christoph, Kuder-Buletta, Elke, Graber-Sultan, Susanne, Preische, Oliver, Hofmann, Anna, Ikeuchi, Takeshi, Niimi, Yoshiki, Ishii, Kenji, Senda, Michio, Sanchez-Valle, Raquel, Lee, Jae-Hong, Riddle, Meghan, Menard, William, Bodge, Courtney, Surti, Mustafa, Takada, Leonel Tadao, Chhatwal, Jasmeer P., Orozco-Barajas, Maribel, Goate, Alison, Esposito, Bianca, Karch, Celeste M., Marsh, Jacob, Cruchaga, Carlos, Fernandez, Victoria, Gordon, Brian A., Fagan, Anne M., Jerome, Gina, Llibre-Guerra, Jorge, Johnson, Erik C.B., Seyfried, Nicholas T., Bateman, Randall J., Hassenstab, Jason, Perrin, Richard J., Chen, Charles, Flores, Shaney, Friedrichsen, Nelly, Hornbeck, Russ, Jarman, Steve, Koudelis, Deborah, Massoumzadeh, Parinaz, McCullough, Austin, Nicklaus, Joyce, Pulizos, Christine, Candela, Madison, Smith, Hunter, Hobbs, Diana, Scott, Jalen, Levin, Johannes, Xiong, Chengjie, Wang, Peter, Xu, Xiong, Li, Yan, Gremminger, Emily, Ma, Yinjiao, Bui, Ryan, Martins, Ralph, Daniels, Alisha, Mori, Hiroshi, Supnet-Bell, Charlene, Xu, Jinbin, Ringman, John, Sung, Yun Ju, Cruchaga, Carlos

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