RAS isoforms and mutations in cancer at a glance von Hobbs, G Aaron, Der, Channing J, Rossman, Kent L

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Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer von Bryant, Kirsten L., Stalnecker, Clint A., Zeitouni, Daniel, Klomp, Jennifer E., Peng, Sen, Tikunov, Andrey P., Gunda, Venugopal, Pierobon, Mariaelena, Waters, Andrew M., George, Samuel D., Tomar, Garima, Papke, Björn, Hobbs, G. Aaron, Yan, Liang, Hayes, Tikvah K., Diehl, J. Nathaniel, Goode, Gennifer D., Chaika, Nina V., Wang, Yingxue, Zhang, Guo-Fang, Witkiewicz, Agnieszka K., Knudsen, Erik S., Petricoin, Emanuel F., Singh, Pankaj K., Macdonald, Jeffrey M., Tran, Nhan L., Lyssiotis, Costas A., Ying, Haoqiang, Kimmelman, Alec C., Cox, Adrienne D., Der, Channing J.

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Selective Targeting of the KRAS G12C Mutant: Kicking KRAS When It’s Down von Hobbs, G. Aaron, Wittinghofer, Alfred, Der, Channing J.

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Altered RNA Splicing by Mutant p53 Activates Oncogenic RAS Signaling in Pancreatic Cancer von Escobar-Hoyos, Luisa F., Penson, Alex, Kannan, Ram, Cho, Hana, Pan, Chun-Hao, Singh, Rohit K., Apken, Lisa H., Hobbs, G. Aaron, Luo, Renhe, Lecomte, Nicolas, Babu, Sruthi, Pan, Fong Cheng, Alonso-Curbelo, Direna, Morris, John P., Askan, Gokce, Grbovic-Huezo, Olivera, Ogrodowski, Paul, Bermeo, Jonathan, Saglimbeni, Joseph, Cruz, Cristian D., Ho, Yu-Jui, Lawrence, Sharon A., Melchor, Jerry P., Goda, Grant A., Bai, Karen, Pastore, Alessandro, Hogg, Simon J., Raghavan, Srivatsan, Bailey, Peter, Chang, David K., Biankin, Andrew, Shroyer, Kenneth R., Wolpin, Brian M., Aguirre, Andrew J., Ventura, Andrea, Taylor, Barry, Der, Channing J., Dominguez, Daniel, Kümmel, Daniel, Oeckinghaus, Andrea, Lowe, Scott W., Bradley, Robert K., Abdel-Wahab, Omar, Leach, Steven D.

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Redox regulation of Ras and Rho GTPases: mechanism and function von Mitchell, Lauren, Hobbs, G Aaron, Aghajanian, Amir, Campbell, Sharon L

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Evaluation of the selectivity and sensitivity of isoform- and mutation-specific RAS antibodies von Waters, Andrew M, Ozkan-Dagliyan, Irem, Vaseva, Angelina V, Fer, Nicole, Strathern, Leslie A, Hobbs, G Aaron, Tessier-Cloutier, Basile, Gillette, William K, Bagni, Rachel, Whiteley, Gordon R, Hartley, James L, McCormick, Frank, Cox, Adrienne D, Houghton, Peter J, Huntsman, David G, Philips, Mark R, Der, Channing J

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Identification of the nucleotide-free state as a therapeutic vulnerability for inhibition of selected oncogenic RAS mutants von Khan, Imran, Koide, Akiko, Zuberi, Mariyam, Ketavarapu, Gayatri, Denbaum, Eric, Teng, Kai Wen, Rhett, J. Matthew, Spencer-Smith, Russell, Hobbs, G. Aaron, Camp, Ernest Ramsay, Koide, Shohei, O'Bryan, John P.

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STAT3 in tumor fibroblasts promotes an immunosuppressive microenvironment in pancreatic cancer von Lefler, Julia E, MarElia-Bennett, Catherine B, Thies, Katie A, Hildreth, 3rd, Blake E, Sharma, Sudarshana M, Pitarresi, Jason R, Han, Lu, Everett, Caroline, Koivisto, Christopher, Cuitino, Maria C, Timmers, Cynthia D, O'Quinn, Elizabeth, Parrish, Melodie, Romeo, Martin J, Linke, Amanda J, Hobbs, G Aaron, Leone, Gustavo, Guttridge, Denis C, Zimmers, Teresa A, Lesinski, Gregory B, Ostrowski, Michael C

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Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition von Waters, Andrew M., Khatib, Tala O., Papke, Bjoern, Goodwin, Craig M., Hobbs, G. Aaron, Diehl, J. Nathaniel, Yang, Runying, Edwards, A. Cole, Walsh, Katherine H., Sulahian, Rita, McFarland, James M., Kapner, Kevin S., Gilbert, Thomas S.K., Stalnecker, Clint A., Javaid, Sehrish, Barkovskaya, Anna, Grover, Kajal R., Hibshman, Priya S., Blake, Devon R., Schaefer, Antje, Nowak, Katherine M., Klomp, Jennifer E., Hayes, Tikvah K., Kassner, Michelle, Tang, Nanyun, Tanaseichuk, Olga, Chen, Kaisheng, Zhou, Yingyao, Kalkat, Manpreet, Herring, Laura E., Graves, Lee M., Penn, Linda Z., Yin, Hongwei H., Aguirre, Andrew J., Hahn, William C., Cox, Adrienne D., Der, Channing J.

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Glutathiolated Ras: Characterization and implications for Ras activation von Hobbs, G. Aaron, Bonini, Marcelo G., Gunawardena, Harsha P., Chen, Xian, Campbell, Sharon L.

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Targeting sine oculis homeoprotein 1 (SIX1): A review of oncogenic roles and potential natural product therapeutics von Bian, Zhiwei, Benjamin, Menny M., Bialousow, Lucas, Tian, Yintai, Hobbs, G. Aaron, Karan, Dev, Choo, Yeun-Mun, Hamann, Mark T., Wang, Xiaojuan

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Author Correction: Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer von Bryant, Kirsten L., Stalnecker, Clint A., Zeitouni, Daniel, Klomp, Jennifer E., Peng, Sen, Tikunov, Andrey P., Gunda, Venugopal, Pierobon, Mariaelena, Waters, Andrew M., George, Samuel D., Tomar, Garima, Papke, Björn, Hobbs, G. Aaron, Yan, Liang, Hayes, Tikvah K., Diehl, J. Nathaniel, Goode, Gennifer D., Chaika, Nina V., Wang, Yingxue, Zhang, Guo-Fang, Witkiewicz, Agnieszka K., Knudsen, Erik S., Petricoin, Emanuel F., Singh, Pankaj K., Macdonald, Jeffrey M., Tran, Nhan L., Lyssiotis, Costas A., Ying, Haoqiang, Kimmelman, Alec C., Cox, Adrienne D., Der, Channing J.

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Copper is required for oncogenic BRAF signalling and tumorigenesis von Brady, Donita C., Crowe, Matthew S., Turski, Michelle L., Hobbs, G. Aaron, Yao, Xiaojie, Chaikuad, Apirat, Knapp, Stefan, Xiao, Kunhong, Campbell, Sharon L., Thiele, Dennis J., Counter, Christopher M.

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Binge Drinking: Macropinocytosis Promotes Tumorigenic Growth of RAS-Mutant Cancers von Hobbs, G. Aaron, Der, Channing J.

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RAS Mutations Are Not Created Equal von Hobbs, G Aaron, Der, Channing J

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Not all RAS mutations are equal: A detailed review of the functional diversity of RAS hot spot mutations von Burge, Rachel A, Hobbs, G Aaron

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Oncogenic KRAS G12C: Kinetic and redox characterization of covalent inhibition von Huynh, Minh V., Parsonage, Derek, Forshaw, Tom E., Chirasani, Venkat R., Hobbs, G. Aaron, Wu, Hanzhi, Lee, Jingyun, Furdui, Cristina M., Poole, Leslie B., Campbell, Sharon L.

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Concurrent Inhibition of ERK and Farnesyltransferase Suppresses the Growth of HRAS Mutant Head and Neck Squamous Cell Carcinoma von Javaid, Sehrish, Schaefer, Antje, Goodwin, Craig M, Nguyen, Victoria V, Massey, Frances L, Pierobon, Mariaelena, Gambrell-Sanders, Da'Jhnae, Waters, Andrew M, Lambert, Kathryn N, Diehl, J Nathaniel, Hobbs, G Aaron, Wood, Kris C, Petricoin, Emanuel F, Der, Channing J, Cox, Adrienne D

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HSP70-mediated mitochondrial dynamics and autophagy represent a novel vulnerability in pancreatic cancer von Ferretti, Giulia D. S., Quaas, Colleen E., Bertolini, Irene, Zuccotti, Alessandro, Saatci, Ozge, Kashatus, Jennifer A., Sharmin, Salma, Lu, David Y., Poli, Adi Narayana Reddy, Quesnelle, Abigail F., Rodriguez-Blanco, Jezabel, de Cubas, Aguirre A., Hobbs, G. Aaron, Liu, Qin, O’Bryan, John P., Salvino, Joseph M., Kashatus, David F., Sahin, Ozgur, Barnoud, Thibaut

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Functional and biological heterogeneity of KRASQ61 mutations von Huynh, Minh V, Hobbs, G Aaron, Schaefer, Antje, Pierobon, Mariaelena, Carey, Leiah M, Diehl, J Nathaniel, DeLiberty, Jonathan M, Thurman, Ryan D, Cooke, Adelaide R, Goodwin, Craig M, Cook, Joshua H, Lin, Lin, Waters, Andrew M, Rashid, Naim U, Petricoin, Emanuel F, Campbell, Sharon L, Haigis, Kevin M, Simeone, Diane M, Lyssiotis, Costas A, Cox, Adrienne D, Der, Channing J

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