Single cell transcriptomes of normal endometrial derived organoids uncover novel cell type markers and cryptic differentiation of primary tumours von Cochrane, Dawn R, Campbell, Kieran R, Greening, Kendall, Ho, Germain C, Hopkins, James, Bui, Minh, Douglas, J Maxwell, Sharlandjieva, Vassilena, Munzur, Aslı D, Lai, Daniel, DeGrood, Maya, Gibbard, Evan W, Leung, Samuel, Boyd, Niki, Cheng, Angela S, Chow, Christine, Lim, Jamie LP, Farnell, David A, Kommoss, Stefan, Kommoss, Friedrich, Roth, Andrew, Hoang, Lien, McAlpine, Jessica N, Shah, Sohrab P, Huntsman, David G

Volltext

Abstract GMM-030: MODELS AND ANALYTIC TECHNIQUES OF MULLERIAN TISSUE-DERIVED ORGANOIDS von Ho, Germain C., Cochrane, Dawn R., Gibbard, Evan W., Campbell, Kieran, Tessier-Cloutier, Basile, Greening, Kendall, Kalantari, Forouh, Trigo-Gonzalez, Genny, Wang, Yemin, McAlpine, Jessica N., Shah, Sohrab P., Huntsman, David G.

Volltext

Abstract B09: Single-cell RNA sequencing of normal endometrial organoids uncovers novel cell-type markers for prognostication of primary tumor samples von Cochrane, Dawn R., Campbell, Kieran R., Greening, Kendall, Ho, Germain C., Hopkins, James, Bui, Minh, Sharlandjieva, Vassilena, Lai, Daniel, DeGrood, Maya, Gibbard, Evan W., Leung, Samuel, Cheng, Angela S., Lim, Jamie L.P., Neilson, Samantha, Farnell, David, Kommoss, Friedrich, McAlpine, Jessica N., Shah, Sohrab P., Huntsman, David G.

Volltext

Stroke genetics informs drug discovery and risk prediction across ancestries von Jürgenson, Tuuli, Namba, Shinichi, Posner, Daniel C., Kamanu, Frederick K., Koido, Masaru, He, Yunye, Caro, Ilana, Krebs, Kristi, Liaw, Yi-Ching, Parodi, Livia, Bae, Hee-Joon, Chong, Michael R., Tomppo, Liisa, Akinyemi, Rufus, Roshchupkin, Gennady V., Habib, Naomi, Jee, Yon Ho, Thomassen, Jesper Qvist, Abedi, Vida, Cárcel-Márquez, Jara, Nygaard, Marianne, Yonova-Doing, Ekaterina, Knol, Maria J., Lewis, Adam J., Judy, Renae L., Amouyel, Philippe, Bakker, Mark K., Bennett, David A., Bis, Joshua C., Bordes, Constance, Børte, Sigrid, Cain, Anael, Ridker, Paul M., Cho, Kelly, Chen, Zhengming, Cruchaga, Carlos, Cole, John W., de Cid, Rafael, Ferreira, Leslie E., He, Jing, Jeon, Christina E., Jern, Christina, Kamouchi, Masahiro, Keene, Keith L., Konuma, Takahiro, Kumar, Amit, Launer, Lenore J., Lee, Keon-Joo, Li, Jiang, Li, Liming, Manichaikul, Ani, Markus, Hugh S., Meitinger, Thomas, Mitchell, Braxton D., Morisaki, Takayuki, O’Donnell, Martin J., Onland-Moret, N. Charlotte, Ovbiagele, Bruce, Peters, Annette, Rosand, Jonathan, Sabatine, Marc S., Sacco, Ralph L., Saleheen, Danish, Schmidt, Carsten O., Smith, Nicholas L., Sloane, Kelly L., Sutoh, Yoichi, Tiwari, Hemant K., Wennberg, Patrik, Wilson, Peter W. F., Yang, Qiong, Yoon, Kyungheon, Gieger, Christian, Ninomiya, Toshiharu, Grabe, Hans J., Jukema, J. Wouter, Kim, Young Jin, Chen, Pei-Hsin, Mayerhofer, Ernst, Ikram, Mohammad A., Worrall, Bradford B., Lathrop, G. Mark, Riaz, Moeen, Simonsick, Eleanor M., Kõrv, Janika, Zand, Ramin, Prasad, Kameshwar, Frikke-Schmidt, Ruth, Liman, Thomas, Ruigrok, Ynte M., Bastarache, Lisa, Damrauer, Scott M., Rotter, Jerome I., Niiranen, Teemu J., Walters, Robin G., Owolabi, Mayowa O., Huffman, Jennifer E., Kamatani, Yoichiro, Dichgans, Martin, Debette, Stephanie

Volltext

RNF168 regulates R-loop resolution and genomic stability in BRCA1/2-deficient tumors von Patel, Parasvi S, Abraham, Karan Joshua, Guturi, Kiran Kumar Naidu, Halaby, Marie-Jo, Khan, Zahra, Palomero, Luis, Ho, Brandon, Duan, Shili, St-Germain, Jonathan, Algouneh, Arash, Mateo, Francesca, El Ghamrasni, Samah, Barbour, Haithem, Barnes, Daniel R, Beesley, Jonathan, Sanchez, Otto, Berman, Hal K, Brown, Grant W, Affar, El Bachir, Chenevix-Trench, Georgia, Antoniou, Antonis C, Arrowsmith, Cheryl H, Raught, Brian, Pujana, Miquel Angel, Mekhail, Karim, Hakem, Anne, Hakem, Razqallah

Volltext

Difluoromethylene at the γ‑Lactam α‑Position Improves 11-Deoxy-8-aza-PGE1 Series EP4 Receptor Binding and Activity: 11-Deoxy-10,10-difluoro-8-aza-PGE1 Analog (KMN-159) as a Potent... von Barrett, Stephen D, Holt, Melissa C, Kramer, James B, Germain, Bradlee, Ho, Chi S, Ciske, Fred L, Kornilov, Andrei, Colombo, Joseph M, Uzieblo, Adam, O’Malley, James P, Owen, Thomas A, Stein, Adam J, Morano, Maria I

Volltext

Immaturity of microvessels in haemorrhagic plaques is associated with proteolytic degradation of angiogenic factors von Le Dall, Julien, Ho-Tin-Noé, Benoît, Louedec, Liliane, Meilhac, Olivier, Roncal, Carmen, Carmeliet, Peter, Germain, Stéphane, Michel, Jean-Baptiste, Houard, Xavier

Volltext

RNF8 ubiquitylation of XRN2 facilitates R-loop resolution and restrains genomic instability in BRCA1 mutant cells von Krishnan, Rehna, Lapierre, Mariah, Gautreau, Brandon, Nixon, Kevin C J, El Ghamrasni, Samah, Patel, Parasvi S, Hao, Jun, Yerlici, V Talya, Guturi, Kiran Kumar Naidu, St-Germain, Jonathan, Mateo, Francesca, Saad, Amine, Algouneh, Arash, Earnshaw, Rebecca, Shili, Duan, Seitova, Alma, Miller, Joshua, Khosraviani, Negin, Penn, Adam, Ho, Brandon, Sanchez, Otto, Hande, M Prakash, Masson, Jean-Yves, Brown, Grant W, Alaoui-Jamali, Moulay, Reynolds, John J, Arrowsmith, Cheryl, Raught, Brian, Pujana, Miguel A, Mekhail, Karim, Stewart, Grant S, Hakem, Anne, Hakem, Razqallah

Volltext

Arginine Depletion Therapy with ADI-PEG20 Limits Tumor Growth in Argininosuccinate Synthase-Deficient Ovarian Cancer, Including Small-Cell Carcinoma of the Ovary, Hypercalcemic Typ... von Ji, Jennifer X, Cochrane, Dawn R, Tessier-Cloutier, Basile, Chen, Shary Yutin, Ho, Germain, Pathak, Khyatiben V, Alcazar, Isabel N, Farnell, David, Leung, Samuel, Cheng, Angela, Chow, Christine, Colborne, Shane, Negri, Gian Luca, Kommoss, Friedrich, Karnezis, Anthony, Morin, Gregg B, McAlpine, Jessica N, Gilks, C Blake, Weissman, Bernard E, Trent, Jeffrey M, Hoang, Lynn, Pirrotte, Patrick, Wang, Yemin, Huntsman, David G

Volltext

Difluoromethylene at the γ-Lactam α-Position Improves 11-Deoxy-8-aza-PGE 1 Series EP 4 Receptor Binding and Activity: 11-Deoxy-10,10-difluoro-8-aza-PGE 1 Analog (KMN-159) as a Pote... von Barrett, Stephen D, Holt, Melissa C, Kramer, James B, Germain, Bradlee, Ho, Chi S, Ciske, Fred L, Kornilov, Andrei, Colombo, Joseph M, Uzieblo, Adam, O'Malley, James P, Owen, Thomas A, Stein, Adam J, Morano, Maria I

Volltext

The production of Titanium Powder via Hydrogen Reduction of Titanium Tetrachloride by Inductively Coupled RF plasma von Park, Sung-hun, Lee, So-yeong, Lee, Ho-seong, Son, Ho-sang

Volltext

Abstract GMM-020: CELL OF ORIGIN, MUTATION AND MICROENVIRONMENT: MODELING EARLY EVENTS OF ENDOMETRIOSIS ASSOCIATED CANCERS von Cochrane, Dawn R, Tessier-Cloutier, Basile, Ho, Germain, Campbell, Kieran, Gibbard, Evan, Lawrence, Katherine M, Nazeran, Tayyebeh, Karnezis, Anthony N., Salamanca, Clara, Cheng, Angela S, McAlpine, Jessica N, Shah, Sohrab, Hoang, Lien N, Gilks, C Blake, Huntsman, David G

Volltext

Use of 12x/month haemoglobin monitoring with a computer algorithm reduces haemoglobin variability von Ho, Warren R, Germain, Michael J, Garb, Jane, Picard, Sue, Mackie, Molly-Kate, Bartlett, Cherry, Will, Eric J

Volltext

Kinetic Study of Selective Chlorination of Iron in Ilmenite Ore von Lee, So-Yeong, Park, Sung-Hun, Sohn, Ho-Sang

Volltext

Microscopic strain localisation in WAAM Ti-6Al-4V during uniaxial tensile loading von Lunt, David, Ho, Alistair, Davis, Alec, Martina, Filomeno, Hönnige, Jan, Quinta da Fonseca, João, Prangnell, Phillip

Volltext

GW170817 : observation of gravitational waves from a binary neutron star inspiral von Abbott, R, Adya, V. B, Anderson, W. G, Austin, C, Barker, D, Bayley, J. C, Bhandare, R, Birch, J, Bloemen, S, Bork, R, Brady, P. R, Brown, D. A, Cabero, M, Cavalier, F, Cerdá-Durán, P, Chia, H, Chow, J. H, Chung, S, Clearwater, P, Cohadon, P.-F, Colla, A, Cunningham, L, DeBra, D, De Laurentis, M, Dergachev, V, Dhurandhar, S, Di Girolamo, T, Drago, M, Driggers, J. C, Eggenstein, H.-B, Farinon, S, Fehrmann, H, Fishbach, M, Fisher, R. P, Flaminio, R, Frasca, S, Frey, R, Fries, E. M, Gabbard, H, Gergely, L, Ghosh, Abhirup, Gushwa, K. E, Gustafson, E. K, Iyer, B. R, Kapadia, S. J, Katsavounidis, E, Katzman, W, Khazanov, E. A, Kim, K, Klimenko, S, Kumar, P, Kwang, S, Lackey, B. D, Leroy, N, Lynch, R, Markakis, C, Marquina, A, Martelli, F, Mason, K, Mastrogiovanni, S, McRae, T, Meadors, G. D, Melatos, A, Milovich-Goff, M. C, Ming, J, Mukherjee, D, Muñiz, E. A, Nelson, T. J. N, Oberling, J, Pai, A, Pai, S. A, Papa, M. A, Patil, M, Pichot, M, Poe, M, Popolizio, P, Prodi, G. A, Rei, L, Robie, R, Rowan, S, Sanchez, E. J, Schnabel, R, Smith, R. J. E, Stratta, G, Sutton, P. J, Szczepańczyk, M. J, Tápai, M, Thorne, K. S, Traylor, G, Tse, M, Vallisneri, M, Vander-Hyde, D. C, van Heijningen, J. V, van Veggel, A. A, Vitale, S, Wang, H, Wang, J. Z, Weßels, P, Williams, R. D, Wittel, H

Volltext

First narrow-band search for continuous gravitational waves from known pulsars in advanced detector data von Abbott, R, Adya, V. B, Allocca, A, Altin, P. A, Anderson, S. B, Angelova, S. V, Araya, M. C, Ast, M, Aston, S. M, Astone, P, Babak, S, Banagiri, S, Bazzan, M, Bejger, M, Belahcene, I, Bizouard, M. A, Boer, M, Brunett, S, Cadonati, L, Cagnoli, G, Carbognani, F, Carney, M. F, Cesarini, E, Charlton, P, Constancio, M, Coughlin, S. B, Dálya, Gergely, De, S, Del Pozzo, W, Denker, T, Di Fiore, L, Estevez, D, Favata, M, Ferrini, F, Freise, A, Frolov, V. V, Gammaitoni, L, Gayathri, V, Hall, E. D, Hamilton, E. Z, Hanks, J, Haster, C.-J, Heidmann, A, Hennig, J, Hu, Y. M, Huet, D, Huttner, S. H, Jiménez-Forteza, F, Karvinen, K. S, Katsavounidis, E, Khan, Z, Kimbrell, S. J, Knowles, T. D, Lee, H. K, Leroy, N, Lockerbie, N. A, Loriette, V, Lough, J. D, Marquina, A, Massera, E, Masso-Reid, M, McCuller, L, Michel, C, Mishra, C, Moreno, G, Munch, J, Naticchioni, L, Nevin, L, Newport, J. M, Nichols, D, Nielsen, A. B, Ogin, G. H, Oppermann, P, O’Reilly, B, Perri, L. M, Poe, M, Quintero, E. A, Rabeling, D. S, Rajan, C, Robie, R, Romel, C. L, Romie, J. H, Sanchez, L. E, Schulte, B. W, Shahriar, M. S, Singer, L. P, Smith, R. J. E, Steinke, M, Steinmeyer, D, Stone, R, Stratta, G, Sturani, R, Taracchini, A, Tsukada, L, Wallace, L, Weinstein, A. J, Weßels, P, Whelan, J. T, Williams, D, Yancey, C. C

Volltext

Stroke genetics informs drug discovery and risk prediction across ancestries von Kamanu, F.K., Koido, M., Caro, I., Lin, K., Winsvold, B.S., Parodi, L., Tomppo, L., Jee, Y.H., Abedi, V., Lewis, A.J., Ago, T., Amouyel, P., Bis, J.C., Bordes, C., Borte, S., Cain, A., Cruchaga, C., Cole, J.W., Cid, R. de, Endres, M., Gudnason, V., Havulinna, A.S., Hyacinth, H.I., Jacob, M.A., Jeon, C.E., Jern, C., Kamouchi, M., Keene, K.L., Kittner, S.J., Kumar, A., Launer, L.J., Lee, K.J., Li, L.M., Manichaikul, A., Markus, H.S., Meitinger, T., Nalls, M.A., Nordestgaard, B.G., Onland-Moret, N.C., Peters, A., Sacco, R.L., Saleheen, D., Sandset, E.C., Salomaa, V., Sasaki, M., Schmidt, C.O., Smith, N.L., Tiedt, S., Trompet, S., Vugt, M. van, Verma, S.S., Wiggins, K.L., Woo, D., Wilson, P.W.F., Xu, H.C., Yang, Q., Yoon, K., Meschia, J.F., Traylor, M., Carty, C.L., Reiner, A., Gottesman, R.F., Furie, K.L., Arnett, D.K., Benavente, O.R., Grewal, R.P., Peddareddygari, L.R., Lindstrom, S., Smith, E.N., Vlieg, A.V., Brody, J.A., Pattee, J.W., Giulianini, F., Ibrahim, M., McCauley, B.M., Kraft, P., Hansen, J.B., Morange, P.E., Kabrhel, C., Dijk, E.J. van, Luijckx, G.J., Oostenbrugge, R.J. van, Leeuw, F.E. de, Levi, C.R., Ilinca, A., Rothwell, P.M., Butterworth, A.S., Rolfs, A., Weir, D., Jood, K., Linkohr, B., Lee, T.H., Anderson, C.D., Jian, X.Q., Schminke, U., Ibanez, L., Muino, E., Roquer, J., Sarnowski, C., Kanai, M.

Volltext bestellen

Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation von Hemani, G, Hannon, E, Dekkers, KF, Castillo-Fernandez, J, Luijk, R, Carnero-Montoro, E, Burrows, K, Suderman, M, Bretherick, AD, Richardson, TG, Klughammer, J, Iotchkova, V, Sharp, G, Shatunov, A, McArdle, WL, Kumar, A, Soriano-Tarraga, C, Giralt-Steinhauer, E, Mason, D, McRae, AF, Corcoran, DL, Sugden, K, Kasela, S, Cugliari, G, Viberti, C, Guarrera, S, Bollepalli, S, Mandaviya, P, Zeng, Y, Clarke, T-K, Walker, RM, Czamara, D, Rezwan, F, Marioni, RE, Awaloff, Y, Germain, M, Aissi, D, Zwamborn, R, van Dongen, J, Hottenga, J-J, Willemsen, G, Xu, C-J, Catala-Moll, F, Wang, C, Bernard, M, Yet, I, Smarts, M, Gorrie-Stone, T, Shaw, C, Ring, SM, Pershagen, G, Melen, E, Lawlor, DA, Martin, NG, Montgomery, GW, Moffitt, TE, Esko, T, Milani, L, Perry, JRB, Sacerdote, C, Panico, S, Arseneault, L, Felix, JF, Rivadeneira, F, Tiemeier, H, van IJzendoorn, MH, Uitterlinden, AG, Jaddoe, VWV, Hale, C, McIntosh, AM, Murray, A, Raikkonen, K, Nohr, EA, Hansen, T, Morgen, CS, Binder, EB, Sunyer, J, Karmaus, W, Deary, IJ, Wray, NR, Slagboom, PE, Morange, P-E, Davies, GE, de Geus, EJC, Boomsma, D, Vonk, JM, Alarcon-Riquelme, ME, Huang, R-C, Pennell, CE, Hughes, AD, Tillin, T, Chaturvedi, N, Pausova, Z, Paus, T, Spector, TD, Kumari, M, Visscher, PM, Bock, C, Gaunt, TR, Relton, CL

Volltext bestellen

Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation von Castillo-Fernandez, J., Luijk, R., Carnero-Montoro, E., Lawson, D.J., Suderman, M., Bretherick, A.D., Richardson, T.G., Klughammer, J., Iotchkova, V., Sharp, G., McArdle, W.L., Soderhall, C., Giralt-Steinhauer, E., Kazmi, N., McRae, A.F., Corcoran, D.L., Sugden, K., Cardona, A., Day, F.R., Cugliari, G., Viberti, C., Gupta, R., Bollepalli, S., Mandaviya, P., Zeng, Y.N., Clarke, T.K., Rezwan, F.I., Marioni, R.E., Lin, T., Awaloff, Y., Germain, M., Aissi, D., Eijk, K. van, Dekker, A., Hottenga, J.J., Xu, C.J., Barturen, G., Kerick, M., Wang, C., Melton, P., Elliott, H.R., Shin, J., Bernard, M., Yet, I., Gorrie-Stone, T., Shaw, C., Chalabi, A. al, Melen, E., Jimenez-Conde, J., Lawlor, D.A., Montgomery, G.W., Moffitt, T.E., Poulton, R., Milani, L., Metspalu, A., Perry, J.R.B., Wareham, N.J., Sacerdote, C., Panico, S., Caspi, A., Arseneault, L., Gagnon, F., Kaprio, J., Rivadeneira, F., Tiemeier, H., Jaddoe, V.W.V., McIntosh, A.M., Hansen, T., Morgen, C.S., Binder, E.B., Lucae, S., Bustamante, M., Sunyer, J., Holloway, J.W., Zhang, H.M., Deary, I.J., Wray, N.R., Beekman, M., Slagboom, P.E., Morange, P.E., Tregouet, D.A., Davies, G.E., Geus, E.J.C. de, Vonk, J.M., Brunekreef, B., Koppelman, G.H., Huang, R.C., Pennell, C.E., Meurs, J. van, Tillin, T., Chaturvedi, N., Pausova, Z., Paus, T., Kumari, M., Visscher, P.M., Smith, G.D., Bock, C., Gaunt, T.R., Heijmans, B.T., Relton, C.L.

Volltext bestellen