Small genomic insertions form enhancers that misregulate oncogenes von Abraham, BJ, Hnisz, D, Weintraub, AS, Kwiatkowski, N, Li, CH, Li, Z, Weichert-Leahey, N, Rahman, S, Liu, Y, Etchin, J, Li, B, Shen, S, Lee, TI, Zhang, J, Look, AT, Mansour, MR, Young, RA

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Unblending of Transcriptional Condensates in Human Repeat Expansion Disease von Basu, Shaon, Mackowiak, Sebastian D., Niskanen, Henri, Knezevic, Dora, Asimi, Vahid, Grosswendt, Stefanie, Geertsema, Hylkje, Ali, Salaheddine, Jerković, Ivana, Ewers, Helge, Mundlos, Stefan, Meissner, Alexander, Ibrahim, Daniel M., Hnisz, Denes

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Hijacking of transcriptional condensates by endogenous retroviruses von Asimi, Vahid, Sampath Kumar, Abhishek, Niskanen, Henri, Riemenschneider, Christina, Hetzel, Sara, Naderi, Julian, Fasching, Nina, Popitsch, Niko, Du, Manyu, Kretzmer, Helene, Smith, Zachary D., Weigert, Raha, Walther, Maria, Mamde, Sainath, Meierhofer, David, Wittler, Lars, Buschow, René, Timmermann, Bernd, Cisse, Ibrahim I., Ameres, Stefan L., Meissner, Alexander, Hnisz, Denes

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T-REX17 is a transiently expressed non-coding RNA essential for human endoderm formation von Landshammer, Alexandro, Bolondi, Adriano, Kretzmer, Helene, Much, Christian, Buschow, René, Rose, Alina, Wu, Hua-Jun, Mackowiak, Sebastian D, Braendl, Bjoern, Giesselmann, Pay, Tornisiello, Rosaria, Parsi, Krishna Mohan, Huey, Jack, Mielke, Thorsten, Meierhofer, David, Maehr, René, Hnisz, Denes, Michor, Franziska, Rinn, John L, Meissner, Alexander

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A histone deacetylase adjusts transcription kinetics at coding sequences during Candida albicans morphogenesis von Hnisz, Denes, Bardet, Anaïs F, Nobile, Clarissa J, Petryshyn, Andriy, Glaser, Walter, Schöck, Ulrike, Stark, Alexander, Kuchler, Karl

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Selective Mediator dependence of cell-type-specifying transcription von Jaeger, Martin G., Schwalb, Björn, Mackowiak, Sebastian D., Velychko, Taras, Hanzl, Alexander, Imrichova, Hana, Brand, Matthias, Agerer, Benedikt, Chorn, Someth, Nabet, Behnam, Ferguson, Fleur M., Müller, André C., Bergthaler, Andreas, Gray, Nathanael S., Bradner, James E., Bock, Christoph, Hnisz, Denes, Cramer, Patrick, Winter, Georg E.

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A histone deacetylase complex mediates biofilm dispersal and drug resistance in Candida albicans von Nobile, Clarissa J, Fox, Emily P, Hartooni, Nairi, Mitchell, Kaitlin F, Hnisz, Denes, Andes, David R, Kuchler, Karl, Johnson, Alexander D

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Aberrant phase separation and nucleolar dysfunction in rare genetic diseases von Mensah, Martin A., Niskanen, Henri, Magalhaes, Alexandre P., Basu, Shaon, Kircher, Martin, Sczakiel, Henrike L., Reiter, Alisa M. V., Elsner, Jonas, Meinecke, Peter, Biskup, Saskia, Chung, Brian H. Y., Dombrowsky, Gregor, Eckmann-Scholz, Christel, Hitz, Marc Phillip, Hoischen, Alexander, Holterhus, Paul-Martin, Hülsemann, Wiebke, Kahrizi, Kimia, Kalscheuer, Vera M., Kan, Anita, Krumbiegel, Mandy, Kurth, Ingo, Leubner, Jonas, Longardt, Ann Carolin, Moritz, Jörg D., Najmabadi, Hossein, Skipalova, Karolina, Snijders Blok, Lot, Tzschach, Andreas, Wiedersberg, Eberhard, Zenker, Martin, Garcia-Cabau, Carla, Buschow, René, Salvatella, Xavier, Kraushar, Matthew L., Mundlos, Stefan, Caliebe, Almuth, Spielmann, Malte, Horn, Denise, Hnisz, Denes

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STAG2 loss rewires oncogenic and developmental programs to promote metastasis in Ewing sarcoma von Adane, Biniam, Alexe, Gabriela, Seong, Bo Kyung A., Lu, Diana, Hwang, Elizabeth E., Hnisz, Denes, Lareau, Caleb A., Ross, Linda, Lin, Shan, Dela Cruz, Filemon S., Richardson, Melissa, Weintraub, Abraham S., Wang, Sarah, Iniguez, Amanda Balboni, Dharia, Neekesh V., Conway, Amy Saur, Robichaud, Amanda L., Tanenbaum, Benjamin, Krill-Burger, John M., Vazquez, Francisca, Schenone, Monica, Berman, Jason N., Kung, Andrew L., Carr, Steven A., Aryee, Martin J., Young, Richard A., Crompton, Brian D., Stegmaier, Kimberly

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An activity-specificity trade-off encoded in human transcription factors von Naderi, Julian, Magalhaes, Alexandre P, Kibar, Gözde, Stik, Grégoire, Zhang, Yaotian, Mackowiak, Sebastian D, Wieler, Hannah M, Rossi, Francesca, Buschow, Rene, Christou-Kent, Marie, Alcoverro-Bertran, Marc, Graf, T. (Thomas), Vingron, Martin, Hnisz, Denes

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An activity-specificity trade-off encoded in human transcription factors von Naderi, Julian, Magalhaes, Alexandre P., Kibar, Gözde, Stik, Gregoire, Zhang, Yaotian, Mackowiak, Sebastian D., Wieler, Hannah M., Rossi, Francesca, Buschow, Rene, Christou-Kent, Marie, Alcoverro-Bertran, Marc, Graf, Thomas, Vingron, Martin, Hnisz, Denes

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Rational optimization of a transcription factor activation domain inhibitor von Basu, Shaon, Martínez-Cristóbal, Paula, Frigolé-Vivas, Marta, Pesarrodona, Mireia, Lewis, Michael, Szulc, Elzbieta, Bañuelos, C. Adriana, Sánchez-Zarzalejo, Carolina, Bielskutė, Stasė, Zhu, Jiaqi, Pombo-García, Karina, Garcia-Cabau, Carla, Zodi, Levente, Dockx, Hannes, Smak, Jordann, Kaur, Harpreet, Batlle, Cristina, Mateos, Borja, Biesaga, Mateusz, Escobedo, Albert, Bardia, Lídia, Verdaguer, Xavier, Ruffoni, Alessandro, Mawji, Nasrin R., Wang, Jun, Obst, Jon K., Tam, Teresa, Brun-Heath, Isabelle, Ventura, Salvador, Meierhofer, David, García, Jesús, Robustelli, Paul, Stracker, Travis H., Sadar, Marianne D., Riera, Antoni, Hnisz, Denes, Salvatella, Xavier

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Aberrant phase separation and nucleolar dysfunction in rare genetic diseases von Mensah, Martin A, Niskanen, Henri, Magalhaes, Alexandre P, Basu, Shaon, Kircher, Martin, Sczakiel, Henrike L, Reiter, Alisa M. V, Elsner, Jonas, Meinecke, Peter, Biskup, Saskia, Chung, Brian H. Y, Dombrowsky, Gregor, Eckmann-Scholz, Christel, Hitz, Marc Phillip, Hoischen, Alexander, Holterhus, Paul-Martin, Hülsemann, Wiebke, Kahrizi, Kimia, Kalscheuer, Vera M, Kan, Anita, Krumbiegel, Mandy, Kurth, Ingo, Leubner, Jonas, Longardt, Ann Carolin, Moritz, Jörg D, Najmabadi, Hossein, Skipalova, Karolina, Snijders Blok, Lot, Tzschach, Andreas, Wiedersberg, Eberhard, Zenker, Martin, Garcia Cabau, Carla, Buschow, René, Salvatella i Giralt, Xavier, Kraushar, Matthew L, Mundlos, Stefan, Caliebe, Almuth, Spielmann, Malte, Horn, Denise, Hnisz, Denes

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STAG2 Mutations Alter Cohesin Ring Function and Provide Therapeutic Vulnerabilities in Acute Myeloid Leukemia von Tothova, Zuzana, Krill-Burger, John M., Day, Daniel S., Haydu, J. Erika, Abraham, Brian J., Landers, Catherine C., Malolepsza, Edyta, Hartigan, Christina R., Holmes, Amie, Donahue, Melanie, Popova, Katerina D., Koochaki, Sebastian, Rivera, Jeanne, Seiler, Michael, Hnisz, Denes, Chen, Edwin, Buonamici, Silvia, Schenone, Monica, D'Andrea, Alan D., Carr, Steven A., Young, Richard A., Ebert, Benjamin L.

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