Constitutional epimutation as a mechanism for cancer causality and heritability? von Hitchins, Megan P.

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Dominantly Inherited Constitutional Epigenetic Silencing of MLH1 in a Cancer-Affected Family Is Linked to a Single Nucleotide Variant within the 5′UTR von Hitchins, Megan P., Rapkins, Robert W., Kwok, Chau-To, Srivastava, Sameer, Wong, Justin J.L., Khachigian, Levon M., Polly, Patsie, Goldblatt, Jack, Ward, Robyn L.

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Identification of constitutional MLH1 epimutations and promoter variants in colorectal cancer patients from the Colon Cancer Family Registry von Ward, Robyn L., Dobbins, Timothy, Lindor, Noralane M., Rapkins, Robert W., Hitchins, Megan P.

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Milestones of Lynch syndrome: 1895–2015 von Lynch, Henry T., Snyder, Carrie L., Shaw, Trudy G., Heinen, Christopher D., Hitchins, Megan P.

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Epimutations and cancer predisposition: importance and mechanisms von Hesson, Luke B, Hitchins, Megan P, Ward, Robyn L

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A systematic review of studies of DNA methylation in the context of a weight loss intervention von Aronica, Lucia, Levine, A Joan, Brennan, Kevin, Mi, Jeffrey, Gardner, Christopher, Haile, Robert W, Hitchins, Megan P

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Erasure of MLH1 methylation in spermatozoa-implications for epigenetic inheritance von Ward, Robyn L, Hitchins, Megan P

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Methylation of the 3p22 region encompassing MLH1 is representative of the CpG island methylator phenotype in colorectal cancer von Wong, Justin J-L, Hawkins, Nicholas J, Ward, Robyn L, Hitchins, Megan P

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The role of epigenetics in Lynch syndrome von Hitchins, Megan P.

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Finding the needle in a haystack: identification of cases of Lynch syndrome with MLH1 epimutation von Hitchins, Megan P.

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Expression of GBGT1 is epigenetically regulated by DNA methylation in ovarian cancer cells von Jacob, Francis, Hitchins, Megan P, Fedier, André, Brennan, Kevin, Nixdorf, Sheri, Hacker, Neville F, Ward, Robyn, Heinzelmann-Schwarz, Viola A

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Role of methylated septin 9 as an adjunct diagnostic and prognostic biomarker in hepatocellular carcinoma von Bannaga, Ayman S., Alvarez, Rocio, Zhou, Lisa, Petchey, Michael, Noufaily, Angela, Hitchins, Megan P., Arasaradnam, Ramesh P.

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Dominantly inherited constitutional epigenetic silencing of MLH1 in a cancer-affected family is linked to a single nucleotide variant within the 5'UTR von Hitchins, Megan P, Rapkins, Robert W, Kwok, Chau-To, Srivastava, Sameer, Wong, Justin J L, Khachigian, Levon M, Polly, Patsie, Goldblatt, Jack, Ward, Robyn L

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Epigenetic changes in childhood asthma von Kumar, Rakesh K, Hitchins, Megan P, Foster, Paul S

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MLH1-methylated endometrial cancer under 60 years of age as the “sentinel” cancer in female carriers of high-risk constitutional MLH1 epimutation von Hitchins, Megan P., Alvarez, Rocio, Zhou, Lisa, Aguirre, Francesca, Dámaso, Estela, Pineda, Marta, Capella, Gabriel, Wong, Justin J.-L., Yuan, Xiaopu, Ryan, Shawnia R., Sathe, Devika S., Baxter, Melanie D., Cannon, Timothy, Biswas, Rakesh, DeMarco, Tiffani, Grzelak, Doreen, Hampel, Heather, Pearlman, Rachel

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Inheritance of a Cancer-Associated MLH1 Germ-Line Epimutation von Hitchins, Megan P, Wong, Justin J.L, Suthers, Graeme, Suter, Catherine M, Martin, David I.K, Hawkins, Nicholas J, Ward, Robyn L

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Implementation of Novel Pyrosequencing Assays to Screen for Common Mutations of BRAF and KRAS in a Cohort of Sporadic Colorectal Cancers von Packham, Deborah, Ward, Robyn L, Ap Lin, Vita, Hawkins, Nicholas J, Hitchins, Megan P

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Methylated SEPTIN9 plasma test for colorectal cancer detection may be applicable to Lynch syndrome von Hitchins, Megan P, Vogelaar, Ingrid P, Brennan, Kevin, Haraldsdottir, Sigurdis, Zhou, Nianmin, Martin, Brock, Alvarez, Rocio, Yuan, Xiaopu, Kim, Sungjin, Guindi, Maha, Hendifar, Andrew E, Kalady, Matthew F, DeVecchio, Jennifer, Church, James M, de la Chapelle, Albert, Hampel, Heather, Pearlman, Rachel, Christensen, Maria, Snyder, Carrie, Lanspa, Stephen J, Haile, Robert W, Lynch, Henry T

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Immunotherapy for deficient mismatch repair (dMMR) pancreatic ductal adenocarcinoma von Ebia, Matthew I, Hitchins, Megan P, Hendifar, Andrew E

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The MGMT promoter SNP rs16906252 is a risk factor for MGMT methylation in glioblastoma and is predictive of response to temozolomide von Rapkins, Robert W, Wang, Fan, Nguyen, HuyTram N, Cloughesy, Timothy F, Lai, Albert, Ha, Wendy, Nowak, Anna K, Hitchins, Megan P, McDonald, Kerrie L

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