Efficacy and safety of a crystalline lactulose preparation (SK-1202) in Japanese patients with chronic constipation: a randomized, double-blind, placebo-controlled, dose-finding st... von Kasugai, Kunio, Iwai, Hisakazu, Kuboyama, Noboru, Yoshikawa, Aya, Fukudo, Shin

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Evaluation of Human Hepatocytes Cultured by Three-dimensional Spheroid Systems for Drug Metabolism von Ohkura, Takako, Ohta, Kunihiro, Nagao, Takuya, Kusumoto, Kumiko, Koeda, Akiko, Ueda, Tadayoshi, Jomura, Tomoko, Ikeya, Takeshi, Ozeki, Emiko, Wada, Kazuki, Naitoh, Kazushi, Inoue, Yukiko, Takahashi, Naoki, Iwai, Hisakazu, Arakawa, Hiroshi, Ogihara, Takuo

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Cross‐over study in hyperammonemia patients for efficacy, safety, and acceptability of a new lactulose preparation (SK‐1202) compared to approved drug von Yoshiji, Hitoshi, Karino, Yoshiyasu, Suzuki, Yoshiyuki, Suzuki, Fumitaka, Uejima, Masakazu, Aikata, Hiroshi, Chayama, Kazuaki, Iwai, Hisakazu, Suzuki, Eiji, Kumada, Hiromitsu

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Detection of incidental breast tumors by noncontrast spiral computed tomography of the chest von Shojaku, Hiroko, Seto, Hikaru, Iwai, Hisakazu, Kitazawa, Shinji, Fukushima, Wataru, Saito, Katsuhiko

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Utility of human hepatocyte spheroids for evaluation of hepatotoxicity von Ogihara, Takuo, Iwai, Hisakazu, Inoue, Yukiko, Katagi, Jun, Matsumoto, Norihito, Motoi-Ohtsuji, Makiko, Kakiki, Motoharu, Kaneda, Shinya, Nagao, Takuya, Kusumoto, Kumiko, Ozeki, Emiko, Jomura, Tomoko, Tanaka, Sho, Ueda, Tadayoshi, Ohta, Kunihiro, Ohkura, Takako, Arakawa, Hiroshi, Nagai, Daichi

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Evaluation of Human Hepatocytes Cultured by Three-dimensional Spheroid Systems for Drug Metabolism von Takako OHKURA, Kunihiro OHTA, Takuya NAGAO, Kumiko KUSUMOTO, Akiko KOEDA, Tadayoshi UEDA, Tomoko JOMURA, Takeshi IKEYA, Emiko OZEKI, Kazuki WADA, Kazushi NAITOH, Yukiko INOUE, Naoki TAKAHASHI, Hisakazu IWAI, Hiroshi ARAKAWA, Takuo OGIHARA

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Efficacy and safety of a crystallized lactulose preparation (SK-1202) against chronic constipation in hemodialysis patients von Imai, Hirokazu, Iwai, Hisakazu, Mizutani, Minoru, Kasugai, Kunio

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EFFECTS OF ATROPINE SULFATE ON RAT HARDERIAN GLANDS : CORRELATION BETWEEN MORPHOLOGICAL CHANGES AND PORPHYRIN LEVELS von IWAI, Hisakazu, TAGAWA, Yoshiaki, HAYASAKA, Ikuo, YANAI, Tokuma, MASEGI, Toshiaki

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2-Bromopropane-Induced Hypoplasia of Bone Marrow in Male Rats von Nakajima, Tamie, Shimodaira, Shigetaka, Ichihara, Gaku, Asaeda, Nobuyuki, Kumazawa, Toshihiko, Iwai, Hisakazu, Ichikawa, Ichihito, Kamijima, Michihiro, Yu, Xiaozhong, Xie, Zhelin, Kondo, Hidetaka, Takeuchi, Yasuhiro

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Atrophy of Rat Exorbital Lacrimal Glands Induced by Atropine von Tagawa, Yoshiaki, Iwai, Hisakazu, Kumazawa, Toshihiko, Haruyama, Kiyoshi, Ichikawa, Kazuhito, Fukushima, Shoji

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Histopathologic Findings of Bone Marrow Induced by 2-Bromopropane in Male Rats von Nakajima, Tamie, Shimodaira, Shigetaka, Ichihara, Gaku, Asaeda, Nobuyuki, Kumazawa, Toshihiko, Iwai, Hisakazu, Ichikawa, Ichihito, Kamijima, Michihiro, Yu, Xiaozhong, Xie, Zhelin, Kondo, Hidetaka, Takeuchi, Yasuhiro

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Sarcoidosis Accompanied by Pleural Effusion and Multiple Bronchial Stenoses von MIZUSHIMA, Yutaka, SASSA, Kazuhiko, FUJISHITA, Takashi, IWAI, Hisakazu, YASUMURA, Satoshi, KOBAYASHI, Masashi

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1-Bromopropane, an Alternative to Ozone Layer Depleting Solvents, Is Dose-Dependently Neurotoxic to Rats in Long-Term Inhalation Exposure von Ichihara, Gaku, Kitoh, Junzoh, Yu, Xiaozhong, Asaeda, Nobuyuki, Iwai, Hisakazu, Kumazawa, Toshihiko, Shibata, Eiji, Yamada, Tetsuya, Wang, Hailan, Xie, Zhenlin, Takeuchi, Yasuhiro

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Reproductive Toxicity of 1-Bromopropane, a Newly Introduced Alternative to Ozone Layer Depleting Solvents, in Male Rats von Ichihara, Gaku, Yu, Xiaozhong, Kitoh, Junzoh, Asaeda, Nobuyuki, Kumazawa, Toshihiko, Iwai, Hisakazu, Shibata, Eiji, Yamada, Tetsuya, Wang, Hailan, Xie, Zhenlin, Maeda, Kei-ichiro, Tsukamura, Hiroko, Takeuchi, Yasuhiro

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慢性便秘症合併血液透析患者における結晶ラクツロース製剤 (SK-1202) の便秘に対する作用 von 今井, 裕一, 岩井, 久和, 水谷, 稔, 春日井, 邦夫

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EFFECTS OF ATROPINE SULFATE ON RAT HARDERIAN GLANDS von IWAI, Hisakazu, TAGAWA, Yoshiaki, HAYASAKA, Ikuo, YANAI, Tokuma, MASEGI, Toshiaki

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Evaluation report on the cytotoxicity tests to estimate starting doses for acute oral systemic toxicity tests von Yoji Takahashi, Toshihiko Kasahara, Shinobu Wakuri, Teruaki Kodaira, Hisakazu Iwai, Shigenobu Hagino, Shigeo Kono, Yomiko Iwase

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S3-2 Better safety evaluation using human and rat hepatocytes in spheroids as an in vitro model von Hisakazu Iwai

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Effect of individual fractions released from myofibrils by CAF (Ca2+-activated factor) on Z-disk reconstitution von SUZUKI, Atsushi, SAITO, Makoto, IWAI, Hisakazu, NONAMI, Yoshinobu

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Effects of Repeated Doses of Iodoacetic Acid on Rat Retinae (Preliminary Study) von ASAEDA, Nobuyuki, IWAI, Hisakazu, TAGAWA, Yoshiaki

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