Underage desexing: reply von Hirschhorn, H L

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Biological interpretation of genome-wide association studies using predicted gene functions von Pers, Tune H., Karjalainen, Juha M., Chan, Yingleong, Westra, Harm-Jan, Wood, Andrew R., Yang, Jian, Lui, Julian C., Vedantam, Sailaja, Gustafsson, Stefan, Esko, Tonu, Frayling, Tim, Speliotes, Elizabeth K., Boehnke, Michael, Raychaudhuri, Soumya, Fehrmann, Rudolf S. N., Hirschhorn, Joel N., Franke, Lude

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Hepatic NADH reductive stress underlies common variation in metabolic traits von Goodman, Russell P., Markhard, Andrew L., Shah, Hardik, Sharma, Rohit, Skinner, Owen S., Clish, Clary B., Deik, Amy, Patgiri, Anupam, Hsu, Yu-Han H., Masia, Ricard, Noh, Hye Lim, Suk, Sujin, Goldberger, Olga, Hirschhorn, Joel N., Yellen, Gary, Kim, Jason K., Mootha, Vamsi K.

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Guidelines for investigating causality of sequence variants in human disease von MacArthur, D. G., Manolio, T. A., Dimmock, D. P., Rehm, H. L., Shendure, J., Abecasis, G. R., Adams, D. R., Altman, R. B., Antonarakis, S. E., Ashley, E. A., Barrett, J. C., Biesecker, L. G., Conrad, D. F., Cooper, G. M., Cox, N. J., Daly, M. J., Gerstein, M. B., Goldstein, D. B., Hirschhorn, J. N., Leal, S. M., Pennacchio, L. A., Stamatoyannopoulos, J. A., Sunyaev, S. R., Valle, D., Voight, B. F., Winckler, W., Gunter, C.

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Interrogation of human hematopoiesis at single-cell and single-variant resolution von Ulirsch, Jacob C., Lareau, Caleb A., Bao, Erik L., Ludwig, Leif S., Guo, Michael H., Benner, Christian, Satpathy, Ansuman T., Kartha, Vinay K., Salem, Rany M., Hirschhorn, Joel N., Finucane, Hilary K., Aryee, Martin J., Buenrostro, Jason D., Sankaran, Vijay G.

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Demonstrating stratification in a European American population von Hirschhorn, Joel N, Campbell, Catarina D, Ogburn, Elizabeth L, Lunetta, Kathryn L, Lyon, Helen N, Freedman, Matthew L, Groop, Leif C, Altshuler, David, Ardlie, Kristin G

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Targeted Application of Human Genetic Variation Can Improve Red Blood Cell Production from Stem Cells von Giani, Felix C., Fiorini, Claudia, Wakabayashi, Aoi, Ludwig, Leif S., Salem, Rany M., Jobaliya, Chintan D., Regan, Stephanie N., Ulirsch, Jacob C., Liang, Ge, Steinberg-Shemer, Orna, Guo, Michael H., Esko, Tõnu, Tong, Wei, Brugnara, Carlo, Hirschhorn, Joel N., Weiss, Mitchell J., Zon, Leonard I., Chou, Stella T., French, Deborah L., Musunuru, Kiran, Sankaran, Vijay G.

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Primary Health Care as a Foundation for Strengthening Health Systems in Low- and Middle-Income Countries von Bitton, Asaf, Ratcliffe, Hannah L., Veillard, Jeremy H., Kress, Daniel H., Barkley, Shannon, Kimball, Meredith, Secci, Federica, Wong, Ethan, Basu, Lopa, Taylor, Chelsea, Bayona, Jaime, Wang, Hong, Lagomarsino, Gina, Hirschhorn, Lisa R.

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Comprehensive analysis of schizophrenia-associated loci highlights ion channel pathways and biologically plausible candidate causal genes von Pers, Tune H, Timshel, Pascal, Ripke, Stephan, Lent, Samantha, Sullivan, Patrick F, O'Donovan, Michael C, Franke, Lude, Hirschhorn, Joel N

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Genome-wide association analyses identify variants in developmental genes associated with hypospadias von Geller, Frank, Feenstra, Bjarke, Carstensen, Lisbeth, Pers, Tune H, van Rooij, Iris A L M, Körberg, Izabella Baranowska, Choudhry, Shweta, Karjalainen, Juha M, Schnack, Tine H, Hollegaard, Mads V, Feitz, Wout F J, Roeleveld, Nel, Hougaard, David M, Hirschhorn, Joel N, Franke, Lude, Baskin, Laurence S, Nordenskjöld, Agneta, van der Zanden, Loes F M, Melbye, Mads

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Identification of IL6R and chromosome 11q13.5 as risk loci for asthma von Ferreira, Manuel AR, Dr, Matheson, Melanie C, PhD, Duffy, David L, PhD, Marks, Guy B, Prof, Hui, Jennie, PhD, Le Souëf, Peter, Prof, Danoy, Patrick, PhD, Baltic, Svetlana, PhD, Nyholt, Dale R, PhD, Jenkins, Mark, PhD, Hayden, Catherine, PhD, Willemsen, Gonneke, PhD, Ang, Wei, MSc, Kuokkanen, Mikko, PhD, Beilby, John, PhD, Cheah, Faang, BSc, de Geus, Eco JC, PhD, Ramasamy, Adaikalavan, DPhil, Vedantam, Sailaja, PhD, Salomaa, Veikko, PhD, Madden, Pamela A, PhD, Heath, Andrew C, Prof, Hopper, John L, Prof, Visscher, Peter M, PhD, Musk, Bill, Prof, Leeder, Stephen R, Prof, Jarvelin, Marjo-Riitta, Prof, Pennell, Craig, PhD, Boomsma, Dorret I, Prof, Hirschhorn, Joel N, Prof, Walters, Haydn, Prof, Martin, Nicholas G, Prof, James, Alan, FRACP, Jones, Graham, PhD, Abramson, Michael J, Prof, Robertson, Colin F, FRACP, Dharmage, Shyamali C, PhD, Brown, Matthew A, Prof, Montgomery, Grant W, PhD, Thompson, Philip J, Prof

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A CLK3-HMGA2 Alternative Splicing Axis Impacts Human Hematopoietic Stem Cell Molecular Identity throughout Development von Cesana, Marcella, Guo, Michael H., Cacchiarelli, Davide, Wahlster, Lara, Barragan, Jessica, Doulatov, Sergei, Vo, Linda T., Salvatori, Beatrice, Trapnell, Cole, Clement, Kendell, Cahan, Patrick, Tsanov, Kaloyan M., Sousa, Patricia M., Tazon-Vega, Barbara, Bolondi, Adriano, Giorgi, Federico M., Califano, Andrea, Rinn, John L., Meissner, Alexander, Hirschhorn, Joel N., Daley, George Q.

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Establishing evidence criteria for implementation strategies in the US: a Delphi study for HIV services von McKay, Virginia R, Zamantakis, Alithia, Pachicano, Ana Michaela, Merle, James L, Purrier, Morgan R, Swan, McKenzie, Li, Dennis H, Mustanski, Brian, Smith, Justin D, Hirschhorn, Lisa R, Benbow, Nanette

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The Genetic Landscape of Renal Complications in Type 1 Diabetes von Sandholm, Niina, Van Zuydam, Natalie, Ahlqvist, Emma, Juliusdottir, Thorhildur, Deshmukh, Harshal A, Rayner, N William, Di Camillo, Barbara, Forsblom, Carol, Fadista, Joao, Ziemek, Daniel, Salem, Rany M, Hiraki, Linda T, Pezzolesi, Marcus, Trégouët, David, Dahlström, Emma, Valo, Erkka, Oskolkov, Nikolay, Ladenvall, Claes, Marcovecchio, M Loredana, Cooper, Jason, Sambo, Francesco, Malovini, Alberto, Manfrini, Marco, McKnight, Amy Jayne, Lajer, Maria, Harjutsalo, Valma, Gordin, Daniel, Parkkonen, Maija, Tuomilehto, Jaakko, Lyssenko, Valeriya, McKeigue, Paul M, Rich, Stephen S, Brosnan, Mary Julia, Fauman, Eric, Bellazzi, Riccardo, Rossing, Peter, Hadjadj, Samy, Krolewski, Andrzej, Paterson, Andrew D, Florez, Jose C, Hirschhorn, Joel N, Maxwell, Alexander P, Dunger, David, Cobelli, Claudio, Colhoun, Helen M, Groop, Leif, McCarthy, Mark I, Groop, Per-Henrik

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Assessment of differentially methylated loci in individuals with end-stage kidney disease attributed to diabetic kidney disease: an exploratory study von Smyth, L J, Kilner, J, Nair, V, Liu, H, Brennan, E, Kerr, K, Sandholm, N, Cole, J, Dahlström, E, Syreeni, A, Salem, R M, Nelson, R G, Looker, H C, Wooster, C, Anderson, K, McKay, G J, Kee, F, Young, I, Andrews, D, Forsblom, C, Hirschhorn, J N, Godson, C, Groop, P H, Maxwell, A P, Susztak, K, Kretzler, M, Florez, J C, McKnight, A J

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Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits von Speliotes, Elizabeth K, Yerges-Armstrong, Laura M, Wu, Jun, Hernaez, Ruben, Kim, Lauren J, Palmer, Cameron D, Gudnason, Vilmundur, Eiriksdottir, Gudny, Garcia, Melissa E, Launer, Lenore J, Nalls, Michael A, Clark, Jeanne M, Mitchell, Braxton D, Shuldiner, Alan R, Butler, Johannah L, Tomas, Marta, Hoffmann, Udo, Hwang, Shih-Jen, Massaro, Joseph M, O'Donnell, Christopher J, Sahani, Dushyant V, Salomaa, Veikko, Schadt, Eric E, Schwartz, Stephen M, Siscovick, David S, Voight, Benjamin F, Carr, J Jeffrey, Feitosa, Mary F, Harris, Tamara B, Fox, Caroline S, Smith, Albert V, Kao, W H Linda, Hirschhorn, Joel N, Borecki, Ingrid B

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Burden of Rare Sarcomere Gene Variants in the Framingham and Jackson Heart Study Cohorts von Bick, Alexander G., Flannick, Jason, Ito, Kaoru, Cheng, Susan, Vasan, Ramachandran S., Parfenov, Michael G., Herman, Daniel S., DePalma, Steven R., Gupta, Namrata, Gabriel, Stacey B., Funke, Birgit H., Rehm, Heidi L., Benjamin, Emelia J., Aragam, Jayashri, Taylor, Herman A., Fox, Ervin R., Newton-Cheh, Christopher, Kathiresan, Sekar, O’Donnell, Christopher J., Wilson, James G., Altshuler, David M., Hirschhorn, Joel N., Seidman, J.G., Seidman, Christine

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Identification of ten loci associated with height highlights new biological pathways in human growth von Hirschhorn, Joel N, Lettre, Guillaume, Jackson, Anne U, Gieger, Christian, Schumacher, Fredrick R, Berndt, Sonja I, Sanna, Serena, Eyheramendy, Susana, Voight, Benjamin F, Butler, Johannah L, Guiducci, Candace, Illig, Thomas, Hackett, Rachel, Heid, Iris M, Jacobs, Kevin B, Lyssenko, Valeriya, Uda, Manuela, Boehnke, Michael, Chanock, Stephen J, Groop, Leif C, Hu, Frank B, Isomaa, Bo, Kraft, Peter, Peltonen, Leena, Salomaa, Veikko, Schlessinger, David, Hunter, David J, Hayes, Richard B, Abecasis, Gonçalo R, Wichmann, H-Erich, Mohlke, Karen L

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Redefining the progeroid form of ehlers-danlos syndrome: Report of the fourth patient with B4GALT7 deficiency and review of the literature von Guo, Michael H., Stoler, Joan, Lui, Julian, Nilsson, Ola, Bianchi, Diana W., Hirschhorn, Joel N., Dauber, Andrew

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New susceptibility loci associated with kidney disease in type 1 diabetes von Sandholm, Niina, Salem, Rany M, McKnight, Amy Jayne, Brennan, Eoin P, Forsblom, Carol, Isakova, Tamara, McKay, Gareth J, Williams, Winfred W, Sadlier, Denise M, Mäkinen, Ville-Petteri, Swan, Elizabeth J, Palmer, Cameron, Boright, Andrew P, Ahlqvist, Emma, Deshmukh, Harshal A, Keller, Benjamin J, Huang, Huateng, Ahola, Aila J, Fagerholm, Emma, Gordin, Daniel, Harjutsalo, Valma, He, Bing, Heikkilä, Outi, Hietala, Kustaa, Kytö, Janne, Lahermo, Päivi, Lehto, Markku, Lithovius, Raija, Osterholm, Anne-May, Parkkonen, Maija, Pitkäniemi, Janne, Rosengård-Bärlund, Milla, Saraheimo, Markku, Sarti, Cinzia, Söderlund, Jenny, Soro-Paavonen, Aino, Syreeni, Anna, Thorn, Lena M, Tikkanen, Heikki, Tolonen, Nina, Tryggvason, Karl, Tuomilehto, Jaakko, Wadén, Johan, Gill, Geoffrey V, Prior, Sarah, Guiducci, Candace, Mirel, Daniel B, Taylor, Andrew, Hosseini, S Mohsen, Parving, Hans-Henrik, Rossing, Peter, Tarnow, Lise, Ladenvall, Claes, Alhenc-Gelas, François, Lefebvre, Pierre, Rigalleau, Vincent, Roussel, Ronan, Tregouet, David-Alexandre, Maestroni, Anna, Maestroni, Silvia, Falhammar, Henrik, Gu, Tianwei, Möllsten, Anna, Cimponeriu, Danut, Ioana, Mihai, Mota, Maria, Mota, Eugen, Serafinceanu, Cristian, Stavarachi, Monica, Hanson, Robert L, Nelson, Robert G, Kretzler, Matthias, Colhoun, Helen M, Panduru, Nicolae Mircea, Gu, Harvest F, Brismar, Kerstin, Zerbini, Gianpaolo, Hadjadj, Samy, Marre, Michel, Groop, Leif, Lajer, Maria, Bull, Shelley B, Waggott, Daryl, Paterson, Andrew D, Savage, David A, Bain, Stephen C, Martin, Finian, Hirschhorn, Joel N, Godson, Catherine, Florez, Jose C, Groop, Per-Henrik, Maxwell, Alexander P

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