Evaluating Crime Prevention Scheme Success: Estimating ‘Outcomes’ or How Many Crimes Were Prevented von Johnson, Shane D., Bowers, Kate J., Jordan, Peter, Mallender, Jacqueline, Davidson, Norman, Hirschfield, Alexander F. G.

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Factors Associated With Outcomes of Patients With Primary Sclerosing Cholangitis and Development and Validation of a Risk Scoring System von Goode, Elizabeth C., Clark, Allan B., Mells, George F., Srivastava, Brijesh, Spiess, Kelly, Gelson, William T.H., Trivedi, Palak J., Lynch, Kate D., Castren, Edit, Vesterhus, Mette N., Karlsen, Tom H., Ji, Sun‐Gou, Anderson, Carl A., Thorburn, Douglas, Hudson, Mark, Heneghan, Michael A., Aldersley, Mark A., Bathgate, Andrew, Sandford, Richard N., Alexander, Graeme J., Chapman, Roger W., Walmsley, Martine, Hirschfield, Gideon M., Rushbrook, Simon M.

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Seladelpar (MBX-8025), a selective PPAR-δ agonist, in patients with primary biliary cholangitis with an inadequate response to ursodeoxycholic acid: a double-blind, randomised, pla... von Jones, David, Boudes, Pol F, Swain, Mark G, Bowlus, Christopher L, Galambos, Michael R, Bacon, Bruce R, Doerffel, Yvonne, Gitlin, Norman, Gordon, Stuart C, Odin, Joseph A, Sheridan, David, Wörns, Markus-Alexander, Clark, Virginia, Corless, Linsey, Hartmann, Heinz, Jonas, Mark E, Kremer, Andreas E, Mells, George F, Buggisch, Peter, Freilich, Bradley L, Levy, Cynthia, Vierling, John M, Bernstein, David E, Hartleb, Marek, Janczewska, Ewa, Rochling, Fedja, Shah, Hemant, Shiffman, Mitchell L, Smith, John H, Choi, Yun-Jung, Steinberg, Alexandra, Varga, Monika, Chera, Harinder, Martin, Robert, McWherter, Charles A, Hirschfield, Gideon M

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HLA-DPA102:01~B101:01 is a risk haplotype for primary sclerosing cholangitis mediating activation of NKp44+ NK cells von Zecher, Britta F, Schloer, Sebastian, Niehrs, Annika, Padoan, Benedetta, Baumdick, Martin E, Yuki, Yuko, Martin, Maureen P, Glow, Dawid, Niersch, Jennifer, Habermann, Robin, Sebode, Marcial, Ellinghaus, Eva, Körner, Christian, Hoelzemer, Angelique, Fehse, Boris, Oldhafer, Karl J, Schumacher, Udo, Sauter, Guido, Carrington, Mary, Bunders, Madeleine J, Altfeld, Marcus, Harley, Hugh, Halilbasic, Emina, Fevery, Johan, Cleynen, Isabelle, Vermeire, Severine, Ytting, Henriette, Mason, Andrew, Eksteen, Bertus, Farkkila, Martti, Chazouillères, Olivier, Poupon, Raoul, Corpechot, Christophe, Keitel, Verena, Häussinger, Dieter, Schramm, Christoph, Lohse, Ansgar, Manns, Michael E, Lankisch, Tim, Gotthardt, Daniel, Schirmacher, Peter, Zimmer, Vincent, Franke, Andre, Ellinghaus, Eva, Ellinghaus, David, Schreiber, Stefan, Plentz, Ruben, Mulcahy, Hugh E., Shibolet, Oren, Marzioni, Marco, Invernizzi, Pietro, Selmi, Carlo, Tanaka, Atsushi, Ohira, Hiromasa, Ueno, Yoshiyuki, Schrumpf, Erik, Boberg, Kirsten M, Melum, Espen, Vesterhaug, Mette, Milkiewicz, Piotr, Wunsch, Ewa, Pares, Albert, Müllhaupt, Beat, Geier, Andreas, Almer, Sven, Björkström, Niklas, deValleVillalba, Maria Benito, Marschall, Hanns-Ulrich, Jansen, Peter L., Beuers, Ulrich, Kremer, Andreas E., Zweers, Serge, Schaap, Frank G., Hirschfield, Gideon M, Liaskou, Evangelia, Sandford, Richard N, Anderson, Carl A, Liu, Jimmy Z, Pereira, Stephen, Webster, George, Burroughs, Andrew, Khan, Shahid A, Taylor-Robinson, Simon D., Jones, David, Burt, Alastair, Rushbrook, Simon M, Chapman, Roger W, Culver, Emma L., Lindor, Keith, Strazzabosco, Mario, Everson, Greg, Helmke, Steve, Levy, Cynthia, Lazaridis, Konstantinos N, Juran, Brian D, Gores, Gregory, Talwalkar, Jayant, Razumilava, Nataliya, Black, Dennis, Karpen, Saul J.

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Pre-treatment risk stratification in primary biliary cholangitis: a predictive model to guide first-line combination therapy von Carbone, M., Nardi, A., Carpino, G., Heneghan, M., Thorburn, D., Taylor-Robinson, S., Bathgate, A., Zuin, M., Battezzati, P.M., Floreani, A., Giannini, E.G., Donato, M.F., Marzioni, M., Alvaro, D., Miele, L., Marra, F., Ainsworth, H., Muratori, L., Bonato, G., Ronca, V., Cristoferi, L., Stocken, D., Cardinale, V., Hirschfield, G., Alexander, G.J.M., Sandford, R., Jones, D., Invernizzi, P., Mells, G.

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THU-218 - Pre-treatment risk stratification in primary biliary cholangitis: a predictive model to guide first-line combination therapy von Carbone, M., Nardi, A., Carpino, G., Heneghan, M., Thorburn, D., Taylor-Robinson, S., Bathgate, A., Zuin, M., Battezzati, P.M., Floreani, A., Giannini, E.G., Donato, M.F., Marzioni, M., Alvaro, D., Miele, L., Marra, F., Ainsworth, H., Muratori, L., Bonato, G., Ronca, V., Cristoferi, L., Stocken, D., Cardinale, V., Hirschfield, G., Alexander, G.J.M., Sandford, R., Jones, D., Invernizzi, P., Mells, G.

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P1147 : Validation of an alkaline phosphatase and bilirubin response criterion as biomarker for transplant-free survival in primary biliary cirrhosis in the world's two largest coh... von Carbone, M, Harms, M.H, Lindor, K, Hirschfield, G.M, Lammers, W.J, Heneghan, M, Janssen, H.L, Neuberger, J.M, Thorburn, D, Pares, A, Sharp, S, Invernizzi, P, Warheam, N, Floreani, A, Bathgate, A, Corpechot, C, Aldersley, M, Mayo, M, LaRusso, N.F, Nevens, F, Alexander, G.J, Kowdley, K.V, Sandford, R.N, Mason, A.L, Jones, D, van Buuren, H.R, Mells, G, Hansen, B.E

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Pre-treatment risk stratification in primary biliary cholangitis: A predictive model to guide first-line combination therapy von Carbone, M., Nardi, A., Carpino, G., Cardinale, V., Ainsworth, H., Heneghan, M., Thorburn, D., Bathgate, A., Jones, R., Neuberger, J.M., Battezzati, P.M., Zuin, M., Taylor-Robinson, S., Donato, M., Kirby, J., Mitchell-Thain, R., Floreani, A., Sampaziotis, F., Muratori, L., Alvaro, D., Marzioni, M., Miele, L., Marra, F., Giannini, E., Gaudio, E., Ronca, V., Bonato, G., Cristoferi, L., Malinverno, F., Gerussi, A., Cordell, H.J., Hirschfield, G.M., Stocken, D., Alexander, G.J., Sandford, R.N., Jones, D.E., Invernizzi, P., Mells, G.F.

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SAT-372 - Genotype-Phenotype Analysis across 130,422 Genetic Variants Identifies Rspo3 as the First Genome-Wide Significant Modifier Gene in Primary Sclerosing Cholangitis von Alberts, R., de Vries, E.M., Alexander, G., Alvaro, D., Bergquist, A., Beuers, U., Björnsson, E., Boberg, K.M., Bowlus, C.L., Chapman, R.W., Chazouilléres, O., Cheung, A., Dalekos, G., Eksteen, B., Eaton, J.E., Ellinghaus, D., Färkkilä, M., Festen, E.A., Floreani, A., Folseraas, T., Goode, E., Gotthardt, D.N., Hirschfield, G.M., van Hoek, B., Hohenester, S., Holm, K., Hov, J.R., Imhann, F., Invernizzi, P., Jiang, X., Juran, B.D., Lazaridis, K.N., Leppa, V., Liu, J.Z., Löfberg, J., Manns, M.P., Marschall, H.-U., Marzioni, M., Mason, A.L., Melum, E., Müller, T., Milkiewicz, P., Pares, A., Pelkonen, V., Pinzani, M., Rombouts, K., Rupp, C., Rushbrook, S.M., Rust, C., Sampaziotis, F., Sandford, R.N., Schramm, C., Schreiber, S., Schrumpf, E., Silverberg, M., Srivastava, B., Sterneck, M., Teufel, A., Tittmann, L., Vallier, L., Vila, A.V., de Vries, B.A., Weismüller, T.J., Wijmenga, C., Zachou, K., Franke, A., Anderson, C.A., Karlsen, T.H., Ponsioen, C.Y., Weersma, K.

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Genotype-Phenotype Analysis across 130,422 Genetic Variants Identifies Rspo3 as the First Genome-Wide Significant Modifier Gene in Primary Sclerosing Cholangitis von Alberts, R, de Vries, E.M, Alexander, G, Alvaro, D, Bergquist, A, Beuers, U, Björnsson, E, Boberg, K.M, Bowlus, C.L, Chapman, R.W, Chazouilléres, O, Cheung, A, Dalekos, G, Eksteen, B, Eaton, J.E, Ellinghaus, D, Färkkilä, M, Festen, E.A, Floreani, A, Folseraas, T, Goode, E, Gotthardt, D.N, Hirschfield, G.M, van Hoek, B, Hohenester, S, Holm, K, Hov, J.R, Imhann, F, Invernizzi, P, Jiang, X, Juran, B.D, Lazaridis, K.N, Leppa, V, Liu, J.Z, Löfberg, J, Manns, M.P, Marschall, H.-U, Marzioni, M, Mason, A.L, Melum, E, Müller, T, Milkiewicz, P, Pares, A, Pelkonen, V, Pinzani, M, Rombouts, K, Rupp, C, Rushbrook, S.M, Rust, C, Sampaziotis, F, Sandford, R.N, Schramm, C, Schreiber, S, Schrumpf, E, Silverberg, M, Srivastava, B, Sterneck, M, Teufel, A, Tittmann, L, Vallier, L, Vila, A.V, de Vries, B.A, Weismüller, T.J, Wijmenga, C, Zachou, K, Franke, A, Anderson, C.A, Karlsen, T.H, Ponsioen, C.Y, Weersma, K

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Pre-treatment prediction of response to ursodeoxycholic acid (UDCA) in primary biliary cholangitis: the UDCA Response Score von Carbone, M, Nardi, A, Flack, S, Carpino, G, Varvaropoulou, N, Gavrila, C, Spicer, A, Badrock, J, Bernuzzi, F, Cardinale, V, Ainsworth, HF, Heneghan, MA, Thorburn, D, Bathgate, A, Jones, R, Neuberger, JM, Battezzati, PM, Zuin, M, Taylor-Robinson, S, Donato, M, Kirby, J, Mitchell-Thain, R, Floreani, A, Sampaziotis, F, Muratori, L, Alvaro, D, Marzioni, M, Miele, L, Marra, F, Giannini, E, Gaudio, E, Ronca, V, Bonato, G, Cristoferi, L, Malinverno, F, Gerussi, A, Stocken, DD, Cordell, HJ, Hirschfield, GM, Alexander, GJ, Sandford, RN, Jones, DE, Invernizzi, P, Mells, GF

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Pretreatment prediction of response to ursodeoxycholic acid in primary biliary cholangitis: development and validation of the UDCA Response Score von Carbone, M, Nardi, A, Flack, S, Carpino, G, Varvaropoulou, N, Gavrila, C, Spicer, A, Badrock, J, Bernuzzi, F, Cardinale, V, Ainsworth, HF, Heneghan, MA, Thorburn, D, Bathgate, A, Jones, R, Neuberger, JM, Battezzati, PM, Zuin, M, Taylor-Robinson, S, Donato, MF, Kirby, J, Mitchell-Thain, R, Floreani, A, Sampaziotis, F, Muratori, L, Alvaro, D, Marzioni, M, Miele, L, Marra, F, Giannini, E, Gaudio, E, Ronca, V, Bonato, G, Cristoferi, L, Malinverno, F, Gerussi, A, Stocken, DD, Cordell, HJ, Hirschfield, GM, Alexander, GJ, Sandford, RN, Jones, DE, Invernizzi, P, Mells, GF, Italian PBC Study Group and the UK–PBC Consortium

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Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis von Alberts, R., Vries, E.M.G. de, Goode, E.C., Jiang, X.J., Sampaziotis, F., Rombouts, K., Bottcher, K., Folseraas, T., Weismuller, T.J., Mason, A.L., Wang, W.W., Alexander, G., Alvaro, D., Bergquist, A., Bjorkstrom, N.K., Beuers, U., Bjornsson, E., Boberg, K.M., Bowlus, C.L., Bragazzi, M.C., Carbone, M., Chazouilleres, O., Cheung, A., Dalekos, G., Eaton, J., Eksteen, B., Ellinghaus, D., Farkkila, M., Festen, E.A.M., Floreani, A., Franceschet, I., Gotthardt, D.N., Hirschfield, G.M., Hoek, B. van, Holm, K., Hohenester, S., Hov, J.R., Imhann, F., Invernizzi, P., Juran, B.D., Lenzen, H., Lieb, W., Liu, J.Z., Marschall, H.U., Marzioni, M., Melum, E., Milkiewicz, P., Muller, T., Pares, A., Rupp, C., Rust, C., Sandford, R.N., Schramm, C., Schreiber, S., Schrumpf, E., Silverberg, M.S., Srivastava, B., Sterneck, M., Teufel, A., Vallier, L., Verheij, J., Vila, A.V., Vries, B. de, Zachou, K., Chapman, R.W., Manns, M.P., Pinzani, M., Rushbrook, S.M., Lazaridis, K.N., Franke, A., Anderson, C.A., Karlsen, T.H., Ponsioen, C.Y., Weersma, R.K.

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Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis von Alberts, R, de Vries, EMG, Goode, EC, Jiang, X, Sampaziotis, F, Rombouts, K, Böttcher, K, Folseraas, T, Weismüller, TJ, Mason, AL, Wang, W, Alexander, G, Alvaro, D, Bergquist, A, Björkström, NK, Beuers, U, Björnsson, E, Boberg, KM, Bowlus, CL, Bragazzi, MC, Carbone, M, Chazouillères, O, Cheung, A, Dalekos, G, Eaton, J, Eksteen, B, Ellinghaus, D, Färkkilä, M, Festen, EAM, Floreani, A, Franceschet, I, Gotthardt, DN, Hirschfield, GM, Hoek, BV, Holm, K, Hohenester, S, Hov, JR, Imhann, F, Invernizzi, P, Juran, BD, Lenzen, H, Lieb, W, Liu, JZ, Marschall, H-U, Marzioni, M, Melum, E, Milkiewicz, P, Müller, T, Pares, A, Rupp, C, Rust, C, Sandford, RN, Schramm, C, Schreiber, S, Schrumpf, E, Silverberg, MS, Srivastava, B, Sterneck, M, Teufel, A, Vallier, L, Verheij, J, Vila, AV, Vries, BD, Zachou, K, International PSC Study Group, The UK PSC Consortium, Chapman, RW, Manns, MP, Pinzani, M, Rushbrook, SM, Lazaridis, KN, Franke, A, Anderson, CA, Karlsen, TH, Ponsioen, CY, Weersma, RK

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Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease von Ji, S-G, Juran, BD, Mucha, S, Folseraas, T, Jostins, L, Melum, E, Kumasaka, N, Atkinson, EJ, Schlicht, EM, Liu, JZ, Shah, T, Gutierrez-Achury, J, Boberg, KM, Bergquist, A, Vermeire, S, Eksteen, B, Durie, PR, Farkkila, M, Müller, T, Schramm, C, Sterneck, M, Weismüller, TJ, Gotthardt, DN, Ellinghaus, D, Braun, F, Teufel, A, Laudes, M, Lieb, W, Jacobs, G, Beuers, U, Weersma, RK, Wijmenga, C, Marschall, H-U, Milkiewicz, P, Pares, A, Kontula, K, Chazouillères, O, Invernizzi, P, Goode, E, Spiess, K, Moore, C, Sambrook, J, Ouwehand, WH, Roberts, DJ, Danesh, J, Floreani, A, Gulamhusein, AF, Eaton, JE, Schreiber, S, Coltescu, C, Bowlus, CL, Luketic, VA, Odin, JA, Chopra, KB, Kowdley, KV, Chalasani, N, Manns, MP, Srivastava, B, Mells, G, Sandford, RN, Alexander, G, Gaffney, DJ, Chapman, RW, Hirschfield, GM, de Andrade, M, UK-PSC Consortium, International IBD Genetics Consortium, International PSC Study Group, Rushbrook, SM, Franke, A, Karlsen, TH, Lazaridis, KN, Anderson, CA

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