Synthesis and structure–activity relationships of new carbonyl guanidine derivatives as novel dual 5-HT2B and 5-HT7 receptor antagonists von Moritomo, Ayako, Yamada, Hiroyoshi, Watanabe, Toshihiro, Itahana, Hirotsune, Akuzawa, Shinobu, Okada, Minoru, Ohta, Mitsuaki

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Synthesis and structure–activity relationships of new carbonyl guanidine derivatives as novel dual 5-HT2B and 5-HT7 receptor antagonists. Part 2 von Moritomo, Ayako, Yamada, Hiroyoshi, Watanabe, Toshihiro, Itahana, Hirotsune, Koga, Yuji, Akuzawa, Shinobu, Okada, Minoru

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Synthesis and pharmacological evaluation of optically pure, novel carbonyl guanidine derivatives as dual 5-HT2B and 5-HT7 receptor antagonists von Moritomo, Ayako, Yamada, Hiroyoshi, Matsuzawa-Nomura, Takaho, Watanabe, Toshihiro, Itahana, Hirotsune, Oku, Makoto, Akuzawa, Shinobu, Okada, Minoru

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Antinociceptive profile of a selective metabotropic glutamate receptor 1 antagonist YM-230888 in chronic pain rodent models von Kohara, Atsuyuki, Nagakura, Yukinori, Kiso, Tetsuo, Toya, Takashi, Watabiki, Tomonari, Tamura, Seiji, Shitaka, Yoshitsugu, Itahana, Hirotsune, Okada, Masamichi

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Diversity of Calcium Signaling by Metabotropic Glutamate Receptors von Kawabata, S, Kohara, A, Tsutsumi, R, Itahana, H, Hayashibe, S, Yamaguchi, T, Okada, M

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Synthesis and pharmacological evaluation of optically pure, novel carbonyl guanidine derivatives as dual 5-HT sub(2B) and 5-HT sub(7) receptor antagonists von Moritomo, Ayako, Yamada, Hiroyoshi, Matsuzawa-Nomura, Takaho, Watanabe, Toshihiro, Itahana, Hirotsune, Oku, Makoto, Akuzawa, Shinobu, Okada, Minoru

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Cycloaddition reactions of a 3-(1,3-butadienyl)cephalosporin and antibacterial activity of new cephem derivatives von HARA, R, ITAHANA, H, SAKAMOTO, K, HISAMICHI, H, NAGANO, N

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Novel 5-Hydroxytryptamine 4 (5-HT4) Receptor Agonists. Synthesis and Gastroprokinetic Activity of 4-Amino-N (2-(1-aminocycloalkan-1-yl)ethyl)-5-chloro-2 methoxybenzamides von SUZUKI, Takeshi, IMANISHI, Naoki, ITAHANA, Hirotsune, WATANUKI, Susumu, MIYATA, Keiji, OHTA, Mitsuaki, NAKAHARA, Hideaki, YAMAGIWA, Yoko, MASE, Toshiyasu

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Synthesis and Biological Activity of New Cephem Compounds with a 3-(2-Butenyl)- and a 3-(1,3-Butadienyl)groupat Their 3-Position von HARA, RYUICHIRO, ITAHANA, HIROTSUNE, HISAMICHI, HIROYUKI, FUKUOKA, SUMIE, NAGANO, NORIAKI

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P2N-33 Antinociceptive effects of YM-230888, a potent, selective and orally-active antagonist of type 1 metabotropic glutamate receptors, at chronic pain models von Atsuyuki Kohara, Yukinori Nagakura, Tetsuo Kiso, Takashi Toya, Seiji Tamura, Tomonari Watabiki, Yoshitsugu Shitaka, Hirotsune Itahana, Masamichi Okada

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Enantioselective synthesis of neoambrosin, parthenin, and dihydroisoparthenin von Asaoka, Morio, Ohkubo, Taketoshi, Itahana, Hirotsune, Kosaka, Takatoshi, Takei, Hisashi

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Cyeloaddition Reactions of a 3-(1, 3-Butadienyl)cephalosporin and Antibacterial Activity of New Cephem Derivatives von HARA, RYUICHIRO, ITAHANA, HIROTSUNE, SAKAMOTO, KENICHIRO, HISAMICHI, HIROYUKI, NAGANO, NORIAKI

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Novel 5-Hydroxytryptamine 4 (5-HT4) Receptor Agonists. Synthesis and Gastroprokinetic Activity of 4-Amino-N-[2-(1-aminocycloalkan-1-yl)ethyl]-5-chloro-2-methoxybenzamides von SUZUKI, Takeshi, IMANISHI, Naoki, ITAHANA, Hirotsune, WATANUKI, Susumu, MIYATA, Keiji, OHTA, Mitsuaki, NAKAHARA, Hideaki, YAMAGIWA, Yoko, MASE, Toshiyasu

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A facile synthesis of 3-(1,3-butadienyl)cephalosporins von Nagano, Noriaki, Itahana, Hirotsune, Hisamichi, Hiroyuki, Sakamoto, Kenichiro, Hara, Ryuichiro

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Synthesis of Novel Restricted Diamines; 2-(1 -Aminocycloalkan-1-YL)ethylamines von Suzuki, Takeshi, Imanishi, Naoki, Itahana, Hirotsune, Watanuki, Susumu, Ohta, Mitsuaki, Mase, Toshiyasu

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Synthesis and Biological Activity of New Cephem Compounds with a 3-(2-Butenyl)-and a 3-(1, 3-Butadienyl)group at Their 3-Position von HARA, RYUICHIRO, ITAHANA, HIROTSUNE, HISAMICHI, HIROYUKI, FUKUOKA, SUMIE, NAGANO, NORIAKI

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Acylguanidine derivative or salt thereof von ITAHANA HIROTSUNE, NOZAWA EISUKE, HARADA KOICHIRO, YAMADA HIROYOSHI, MORITOMO AYAKO, MATSUZAWA TAKAHO, AKUZAWA SHINOBU

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Acylguanidine derivative or salt thereof von Yamada, Hiroyoshi, Itahana, Hirotsune, Moritomo, Ayako, Matsuzawa, Takaho, Nozawa, Eisuke, Akuzawa, Shinobu, Harada, Koichiro

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ACYLGUANIDINDERIVAT ODER SALZ DAVON von HARADA, KOICHIRO, YAMADA, HIROYOSHI, NOZAWA, EISUKE, MORITOMO, AYAKO, ITAHANA, HIROTSUNE, MATSUZAWA, TAKAHO, AKUZAWA, SHINOBU

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ACYLGUANIDINE DERIVATIVE OR SALT THEREOF von HARADA, KOICHIRO, YAMADA, HIROYOSHI, NOZAWA, EISUKE, MORITOMO, AYAKO, ITAHANA, HIROTSUNE, MATSUZAWA, TAKAHO, AKUZAWA, SHINOBU

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