Whole-exome sequencing identifies recurrent SF3B1 R625 mutation and comutation of NF1 and KIT in mucosal melanoma von Hintzsche, Jennifer D, Gorden, Nicholas T, Amato, Carol M, Kim, Jihye, Wuensch, Kelsey E, Robinson, Steven E, Applegate, Allison J, Couts, Kasey L, Medina, Theresa M, Wells, Keith R, Wisell, Joshua A, McCarter, Martin D, Box, Neil F, Shellman, Yiqun G, Gonzalez, Rene C, Lewis, Karl D, Tentler, John J, Tan, Aik Choon, Robinson, William A

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Targeting CDK4/6 Represents a Therapeutic Vulnerability in Acquired BRAF/MEK Inhibitor-Resistant Melanoma von Nassar, Kelsey W., Hintzsche, Jennifer D., Bagby, Stacey M., Espinoza, Veronica, Langouet-Astrie, Christophe, Amato, Carol M., Chimed, Tugs-Saikhan, Fujita, Mayumi, Robinson, William, Tan, Aik Choon, Schweppe, Rebecca E.

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ALK Inhibitor Response in Melanomas Expressing EML4-ALK Fusions and Alternate ALK Isoforms von Couts, Kasey L, Bemis, Judson, Turner, Jacqueline A, Bagby, Stacey M, Murphy, Danielle, Christiansen, Jason, Hintzsche, Jennifer D, Le, Anh, Pitts, Todd M, Wells, Keith, Applegate, Allison, Amato, Carol, Multani, Pratik, Chow-Maneval, Edna, Tentler, John J, Shellman, Yiqun G, Rioth, Matthew J, Tan, Aik-Choon, Gonzalez, Rene, Medina, Theresa, Doebele, Robert C, Robinson, William A

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IMPACT web portal: oncology database integrating molecular profiles with actionable therapeutics von Hintzsche, Jennifer D, Yoo, Minjae, Kim, Jihye, Amato, Carol M, Robinson, William A, Tan, Aik Choon

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Pre-Treatment Mutational and Transcriptomic Landscape of Responding Metastatic Melanoma Patients to Anti-PD1 Immunotherapy von Amato, Carol M., Hintzsche, Jennifer D., Wells, Keith, Applegate, Allison, Gorden, Nicholas T., Vorwald, Victoria M., Tobin, Richard P., Nassar, Kelsey, Shellman, Yiqun G., Kim, Jihye, Medina, Theresa M., Rioth, Matthew, Lewis, Karl D., McCarter, Martin D., Gonzalez, Rene, Tan, Aik-Choon, Robinson, William A.

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A Survey of Computational Tools to Analyze and Interpret Whole Exome Sequencing Data von Hintzsche, Jennifer D., Tan, Aik Choon, Robinson, William A.

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DNA-PK inhibition enhances neoantigen diversity and increases T cell responses to immunoresistant tumors von Nielsen, Allison Joy, Albert, Gabriella Kyra, Sanchez, Amelia, Chen, Jiangli, Liu, Jing, Davalos, Andres Sebastian, Geng, Degui, Bradeen, Xander G, Hintzsche, Jennifer D, Robinson, William, McCarter, Martin, Amato, Carol M, Tobin, Richard, Couts, Kasey L, Wilky, Breelyn Ann, Davila, Eduardo

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Genomic profiling of melanomas of unknown primary von Wells, Keith Ryan, Hintzsche, Jennifer, Amato, Carol M, Robinson, William

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Identification of somatic mutations and neoantigens to predict development of autoimmune adverse events to immune therapy in melanoma von Wells, Keith Ryan, Amato, Carol M, Hintzsche, Jennifer, Robinson, William

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Identification of somatic mutations to predict development of autoimmune adverse events to immune therapy in melanoma von Wells, Keith Ryan, Amato, Carol M, Hintzsche, Jennifer, Robinson, William

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Abstract 5002: Investigating the role of NF- κB signaling and immune checkpoint blockade therapy in melanoma von Wells, Keith, Hintzsche, Jennifer, Amato, Carol M., Tobin, Richard, Vorwald, Victoria, McCarter, Martin, Shellman, Yiqun, Tan, Aik Choon, Robinson, William

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SASH1 S519N Variant Links Skin Hyperpigmentation and Premature Hair Graying to Dysfunction of Melanocyte Lineage von Lambert, Karoline A., Clements, Christopher M., Mukherjee, Nabanita, Pacheco, Theresa R., Shellman, Samantha X., Henen, Morkos A., Vögeli, Beat, Goldstein, Nathaniel B., Birlea, Stanca, Hintzsche, Jennifer, Caryotakis, Griffin, Tan, Aik-Choon, Zhao, Rui, Norris, David A., Robinson, William A., Wang, Yizhou, VanTreeck, Jillian G., Shellman, Yiqun G.

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Systematic Analysis of Whole Exome Sequencing Determines RET G691S Polymorphism as Germline Variant in Melanoma von Smith Jr, Brent J., Hintzsche, Jennifer D., Amato, Carol M., Tan, Aik-Choon, Wells, Keith R., Applegate, Allison J., Gonzalez, Rita T., Barr, Jodie R., Robinson, William A.

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Abstract B076: Uncoupling of the cell cycle pathway from the MAPK pathway in BRAF/MEK inhibitor resistant melanoma von Nassar, Kelsey W., Hintzsche, Jennifer, Bagby, Stacey, Langouet-Astrie, Christophe, Samson, Jenny, Amato, Carol, Gordon, Nicholas, Fujita, Mayumi, Schweppe, Rebecca, Robinson, William, Tan, Aik-Choon

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IMPACT: a whole-exome sequencing analysis pipeline for integrating molecular profiles with actionable therapeutics in clinical samples von Hintzsche, Jennifer, Kim, Jihye, Yadav, Vinod, Amato, Carol, Robinson, Steven E, Seelenfreund, Eric, Shellman, Yiqun, Wisell, Joshua, Applegate, Allison, McCarter, Martin, Box, Neil, Tentler, John, De, Subhajyoti, Robinson, William A, Tan, Aik Choon

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Kinase gene fusions in defined subsets of melanoma von Turner, Jacqueline, Couts, Kasey, Sheren, Jamie, Saichaemchan, Siriwimon, Ariyawutyakorn, Witthawat, Avolio, Izabela, Cabral, Ethan, Glogowska, Magdelena, Amato, Carol, Robinson, Steven, Hintzsche, Jennifer, Applegate, Allison, Seelenfreund, Eric, Gonzalez, Rita, Wells, Keith, Bagby, Stacey, Tentler, John, Tan, Aik‐Choon, Wisell, Joshua, Varella‐Garcia, Marileila, Robinson, William

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Insight into the evolution of the Solanaceae from the parental genomes of Petunia hybrida von Bombarely, Aureliano, Moser, Michel, Amrad, Avichai, Bao, Manzhu, Bapaume, Laure, Barry, Cornelius S, Bliek, Mattijs, Boersma, Maaike R, Borghi, Lorenzo, Bruggmann, Rémy, Bucher, Marcel, D'Agostino, Nunzio, Davies, Kevin, Druege, Uwe, Dudareva, Natalia, Egea-Cortines, Marcos, Delledonne, Massimo, Fernandez-Pozo, Noe, Franken, Philipp, Grandont, Laurie, Heslop-Harrison, J S, Hintzsche, Jennifer, Johns, Mitrick, Koes, Ronald, Lv, Xiaodan, Lyons, Eric, Malla, Diwa, Martinoia, Enrico, Mattson, Neil S, Morel, Patrice

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Insight into the evolution of the Solanaceae from the parental genomes of Petunia hybrida von Bombarely, Aureliano, Moser, Michel, Amrad, Avichai, Bao, Manzhu, Bapaume, Laure, Barry, Cornelius S, Bliek, Mattijs, Boersma, Maaike R, Borghi, Lorenzo, Bruggmann, Remy, Bucher, Marcel, D'Agostino, Nunzio, Davies, Kevin, Druege, Uwe, Dudareva, Natalia, Egea-Cortines, Marcos, Delledonne, Massimo, Fernandez-Pozo, Noe, Franken, Philipp, Grandont, Laurie, Heslop-Harrison, J.S, Hintzsche, Jennifer, Johns, Mitrick, Koes, Ronald, Lv, Xiaodan, Lyons, Eric, Malla, Diwa, Martinoia, Enrico, Mattson, Neil S, Morel, Patrice, Mueller, Lukas A, Muhlemann, Joelle, Nouri, Eva, Passeri, Valentina, Pezzotti, Mario, Qi, Qinzhou, Reinhardt, Didier, Rich, Melanie, Richert-Poeggeler, Katja R, Robbins, Tim P, Schatz, Michael C, Schranz, M. Eric, Schuurink, Robert C, Schwarzacher, Trude, Spelt, Kees, Tang, Haibao, Urbanus, Susan L, Vandenbussche, Michiel, Vijverberg, Kitty, Villarino, Gonzalo H, Warner, Ryan M, Weiss, Julia, Yue, Zhen, Zethof, Jan, Quattrocchio, Francesca, Sims, Thomas L, Kuhlemeier, Cris

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