Reference component analysis of single-cell transcriptomes elucidates cellular heterogeneity in human colorectal tumors von Li, Huipeng, Courtois, Elise T, Sengupta, Debarka, Tan, Yuliana, Chen, Kok Hao, Goh, Jolene Jie Lin, Kong, Say Li, Chua, Clarinda, Hon, Lim Kiat, Tan, Wah Siew, Wong, Mark, Choi, Paul Jongjoon, Wee, Lawrence J K, Hillmer, Axel M, Tan, Iain Beehuat, Robson, Paul, Prabhakar, Shyam

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Novel therapeutic targets on the horizon for lung cancer von Tan, Wan-Ling, MRCP, Jain, Amit, MMed, Takano, Angela, MD, Newell, Evan W, PhD, Iyer, N Gopalakrishna, MD, Lim, Wan-Teck, MRCP, Tan, Eng-Huat, MMed, Zhai, Weiwei, PhD, Hillmer, Axel M, PhD, Tam, Wai-Leong, PhD, Tan, Daniel S W, Dr

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Genomic landscape of lung adenocarcinoma in East Asians von Chen, Jianbin, Yang, Hechuan, Teo, Audrey Su Min, Amer, Lidyana Bte, Sherbaf, Faranak Ghazi, Tan, Chu Quan, Alvarez, Jacob Josiah Santiago, Lu, Bingxin, Lim, Jia Qi, Takano, Angela, Nahar, Rahul, Lee, Yin Yeng, Phua, Cheryl Zi Jin, Chua, Khi Pin, Suteja, Lisda, Chen, Pauline Jieqi, Chang, Mei Mei, Koh, Tina Puay Theng, Ong, Boon-Hean, Anantham, Devanand, Hsu, Anne Ann Ling, Gogna, Apoorva, Too, Chow Wei, Aung, Zaw Win, Lee, Yi Fei, Wang, Lanying, Lim, Tony Kiat Hon, Wilm, Andreas, Choi, Poh Sum, Ng, Poh Yong, Toh, Chee Keong, Lim, Wan-Teck, Ma, Siming, Lim, Bing, Liu, Jin, Tam, Wai Leong, Skanderup, Anders Jacobsen, Yeong, Joe Poh Sheng, Tan, Eng-Huat, Creasy, Caretha L., Tan, Daniel Shao Weng, Hillmer, Axel M., Zhai, Weiwei

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Methionine is a metabolic dependency of tumor-initiating cells von Wang, Zhenxun, Yip, Lian Yee, Lee, Jia Hui Jane, Wu, Zhengwei, Chew, Hui Yi, Chong, Pooi Kiat William, Teo, Chin Chye, Ang, Heather Yin-Kuan, Peh, Kai Lay Esther, Yuan, Ju, Ma, Siming, Choo, Li Shi Kimberly, Basri, Nurhidayah, Jiang, Xia, Yu, Qiang, Hillmer, Axel M., Lim, Wan Teck, Lim, Tony Kiat Hon, Takano, Angela, Tan, Eng Huat, Tan, Daniel Shao Weng, Ho, Ying Swan, Lim, Bing, Tam, Wai Leong

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Elucidating the genomic architecture of Asian EGFR-mutant lung adenocarcinoma through multi-region exome sequencing von Nahar, Rahul, Zhai, Weiwei, Zhang, Tong, Takano, Angela, Khng, Alexis J., Lee, Yin Yeng, Liu, Xingliang, Lim, Chong Hee, Koh, Tina P. T., Aung, Zaw Win, Lim, Tony Kiat Hon, Veeravalli, Lavanya, Yuan, Ju, Teo, Audrey S. M., Chan, Cheryl X., Poh, Huay Mei, Chua, Ivan M. L., Liew, Audrey Ann, Lau, Dawn Ping Xi, Kwang, Xue Lin, Toh, Chee Keong, Lim, Wan-Teck, Lim, Bing, Tam, Wai Leong, Tan, Eng-Huat, Hillmer, Axel M., Tan, Daniel S. W.

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Clonal MET Amplification as a Determinant of Tyrosine Kinase Inhibitor Resistance in Epidermal Growth Factor Receptor-Mutant Non-Small-Cell Lung Cancer von Lai, Gillianne G Y, Lim, Tse Hui, Lim, John, Liew, Perry J R, Kwang, Xue Lin, Nahar, Rahul, Aung, Zaw Win, Takano, Angela, Lee, Yin Yeng, Lau, Dawn P X, Tan, Gek San, Tan, Sze Huey, Tan, Wan Ling, Ang, Mei-Kim, Toh, Chee Keong, Tan, Bien Soo, Devanand, Anantham, Too, Chow Wei, Gogna, Apoorva, Ong, Boon Hean, Koh, Tina P T, Kanesvaran, Ravindran, Ng, Quan Sing, Jain, Amit, Rajasekaran, Tanujaa, Yuan, Ju, Lim, Tony Kiat Hon, Lim, Alvin S T, Hillmer, Axel M, Lim, Wan Teck, Iyer, N Gopalakrishna, Tam, Wai Leong, Zhai, Weiwei, Tan, Eng-Huat, Tan, Daniel S W

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Loss of the SWI/SNF-ATPase subunit members SMARCF1 (ARID1A), SMARCA2 (BRM), SMARCA4 (BRG1) and SMARCB1 (INI1) in oesophageal adenocarcinoma von Schallenberg, Simon, Bork, Julian, Essakly, Ahlem, Alakus, Hakan, Buettner, Reinhard, Hillmer, Axel M, Bruns, Christiane, Schroeder, Wolfgang, Zander, Thomas, Loeser, Heike, Gebauer, Florian, Quaas, Alexander

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Detection of gene fusions using targeted next-generation sequencing: a comparative evaluation von Heydt, Carina, Wölwer, Christina B, Velazquez Camacho, Oscar, Wagener-Ryczek, Svenja, Pappesch, Roberto, Siemanowski, Janna, Rehker, Jan, Haller, Florian, Agaimy, Abbas, Worm, Karl, Herold, Thomas, Pfarr, Nicole, Weichert, Wilko, Kirchner, Thomas, Jung, Andreas, Kumbrink, Jörg, Goering, Wolfgang, Esposito, Irene, Buettner, Reinhard, Hillmer, Axel M, Merkelbach-Bruse, Sabine

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Tumor phylogeography reveals block-shaped spatial heterogeneity and the mode of evolution in Hepatocellular Carcinoma von Liu, Xiaodong, Zhang, Ke, Kaya, Neslihan A., Jia, Zhe, Wu, Dafei, Chen, Tingting, Liu, Zhiyuan, Zhu, Sinan, Hillmer, Axel M., Wuestefeld, Torsten, Liu, Jin, Chan, Yun Shen, Hu, Zheng, Ma, Liang, Jiang, Li, Zhai, Weiwei

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An integrative model of pathway convergence in genetically heterogeneous blast crisis chronic myeloid leukemia von Ko, Tun Kiat, Javed, Asif, Lee, Kian Leong, Pathiraja, Thushangi N., Liu, Xingliang, Malik, Simeen, Soh, Sheila Xinxuan, Heng, Xiu Ting, Takahashi, Naoto, Tan, Joanna H.J., Bhatia, Ravi, Khng, Alexis J., Chng, Wee-Joo, Sia, Yee Yen, Fruman, David A., Ng, King Pan, Chan, Zhu En, Xie, Kim Jiajing, Hoi, Qiangze, Chan, Cheryl Xueli, Teo, Audrey S.M., Velazquez Camacho, Oscar, Meah, Wee Yang, Khor, Chiea Chuen, Ong, Chin Thing J., Soon, Wei Jia W., Tan, Patrick, Ng, Pauline C., Chuah, Charles, Hillmer, Axel M., Ong, S. Tiong

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Analysis of tumor mutational burden: correlation of five large gene panels with whole exome sequencing von Heydt, Carina, Rehker, Jan, Pappesch, Roberto, Buhl, Theresa, Ball, Markus, Siebolts, Udo, Haak, Anja, Lohneis, Philipp, Büttner, Reinhard, Hillmer, Axel M., Merkelbach-Bruse, Sabine

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Epigenomic profiling of primary gastric adenocarcinoma reveals super-enhancer heterogeneity von Ooi, Wen Fong, Xing, Manjie, Xu, Chang, Yao, Xiaosai, Ramlee, Muhammad Khairul, Lim, Mei Chee, Cao, Fan, Lim, Kevin, Babu, Deepak, Poon, Lai-Fong, Lin Suling, Joyce, Qamra, Aditi, Irwanto, Astrid, Qu Zhengzhong, James, Nandi, Tannistha, Lee-Lim, Ai Ping, Chan, Yang Sun, Tay, Su Ting, Lee, Ming Hui, Davies, James O. J., Wong, Wai Keong, Soo, Khee Chee, Chan, Weng Hoong, Ong, Hock Soo, Chow, Pierce, Wong, Chow Yin, Rha, Sun Young, Liu, Jianjun, Hillmer, Axel M., Hughes, Jim R., Rozen, Steve, Teh, Bin Tean, Fullwood, Melissa Jane, Li, Shang, Tan, Patrick

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G protein–coupled receptor P2Y5 and its ligand LPA are involved in maintenance of human hair growth von Pasternack, Sandra M, von Kügelgen, Ivar, Aboud, Khalid Al, Lee, Young-Ae, Rüschendorf, Franz, Voss, Katrin, Hillmer, Axel M, Molderings, Gerhard J, Franz, Thomas, Ramirez, Alfredo, Nürnberg, Peter, Nöthen, Markus M, Betz, Regina C

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Variant profiling of colorectal adenomas from three patients of two families with MSH3-related adenomatous polyposis von Perne, Claudia, Peters, Sophia, Cartolano, Maria, Horpaopan, Sukanya, Grimm, Christina, Altmüller, Janine, Sommer, Anna K, Hillmer, Axel M, Thiele, Holger, Odenthal, Margarete, Möslein, Gabriela, Adam, Ronja, Sivalingam, Sugirthan, Kirfel, Jutta, Schweiger, Michal R, Peifer, Martin, Spier, Isabel, Aretz, Stefan

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Predicting the next move: tracking the complexity of lung cancer evolution and metastasis von Lorenz, Carina, Hillmer, Axel M., Brägelmann, Johannes

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PIK3CA and KRAS Amplification in Esophageal Adenocarcinoma and their Impact on the Inflammatory Tumor Microenvironment and Prognosis von Essakly, Ahlem, Loeser, Heike, Kraemer, Max, Alakus, Hakan, Chon, Seung-Hun, Zander, Thomas, Buettner, Reinhard, Hillmer, Axel M., Bruns, Christiane J., Schroeder, Wolfgang, Gebauer, Florian, Quaas, Alexander

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AI-based multi-PRS models outperform classical single-PRS models von Klau, Jan Henric, Maj, Carlo, Klinkhammer, Hannah, Krawitz, Peter M, Mayr, Andreas, Hillmer, Axel M, Schumacher, Johannes, Heider, Dominik

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Androgenetic Alopecia: Identification of Four Genetic Risk Loci and Evidence for the Contribution of WNT Signaling to Its Etiology von Heilmann, Stefanie, Kiefer, Amy K., Fricker, Nadine, Drichel, Dmitriy, Hillmer, Axel M., Herold, Christine, Tung, Joyce Y., Eriksson, Nicholas, Redler, Silke, Betz, Regina C., Li, Rui, Kárason, Ari, Nyholt, Dale R., Song, Kijoung, Vermeulen, Sita H., Kanoni, Stavroula, Dedoussis, George, Martin, Nicholas G., Kiemeney, Lambertus A., Mooser, Vincent, Stefansson, Kari, Brent Richards, J., Becker, Tim, Brockschmidt, Felix F., Hinds, David A., Nöthen, Markus M.

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Amplification of KRAS and its heterogeneity in non-Asian gastric adenocarcinomas von Rehkaemper, Jan, Korenkov, Michael, Quaas, Alexander, Rueschoff, Josef, Pamuk, Aylin, Zander, Thomas, Hillmer, Axel M, Buettner, Reinhard, Hoelscher, Arnulf Heinrich, Bruns, Christiane Josephine, Loeser, Heike, Alakus, Hakan, Schoemig-Markiefka, Birgid

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Why loss of Y? A pan-cancer genome analysis of tumors with loss of Y chromosome von Müller, Philipp, Velazquez Camacho, Oscar, Yazbeck, Ali M., Wölwer, Christina, Zhai, Weiwei, Schumacher, Johannes, Heider, Dominik, Buettner, Reinhard, Quaas, Alexander, Hillmer, Axel M.

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