IRF4 Transcription Factor-Dependent CD11b+ Dendritic Cells in Human and Mouse Control Mucosal IL-17 Cytokine Responses von Schlitzer, Andreas, McGovern, Naomi, Teo, Pearline, Zelante, Teresa, Atarashi, Koji, Low, Donovan, Ho, Adrian W.S., See, Peter, Shin, Amanda, Wasan, Pavandip Singh, Hoeffel, Guillaume, Malleret, Benoit, Heiseke, Alexander, Chew, Samantha, Jardine, Laura, Purvis, Harriet A., Hilkens, Catharien M.U., Tam, John, Poidinger, Michael, Stanley, E. Richard, Krug, Anne B., Renia, Laurent, Sivasankar, Baalasubramanian, Ng, Lai Guan, Collin, Matthew, Ricciardi-Castagnoli, Paola, Honda, Kenya, Haniffa, Muzlifah, Ginhoux, Florent

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Adult Human Fibroblasts Are Potent Immunoregulatory Cells and Functionally Equivalent to Mesenchymal Stem Cells von Haniffa, Muzlifah A, Wang, Xiao-Nong, Holtick, Udo, Rae, Michelle, Isaacs, John D, Dickinson, Anne M, Hilkens, Catharien M. U, Collin, Matthew P

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Dendritic cell maturation and survival are differentially regulated by TNFR1 and TNFR2 von Maney, Nicola J, Reynolds, Gary, Krippner-Heidenreich, Anja, Hilkens, Catharien M U

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Macrophage proliferation distinguishes 2 subgroups of knee osteoarthritis patients von Wood, Matthew J, Leckenby, Adam, Reynolds, Gary, Spiering, Rachel, Pratt, Arthur G, Rankin, Kenneth S, Isaacs, John D, Haniffa, Muzlifah A, Milling, Simon, Hilkens, Catharien Mu

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Endogenous retroelement activation is implicated in IFN-α production and anti-CCP autoantibody generation in early Rheumatoid Arthritis von Cooles, Faye Ah, Pedrola, Gemma V, Naamane, Najib, Pratt, Arthur G, Barron-Millar, Ben, Anderson, Amy E, Hilkens, Catharien Mu, Casement, John, Bondet, Vincent, Duffy, Darragh, Zhang, Fan, Shukla, Ruchi, Isaacs, John D

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A negative feedback loop mediated by STAT3 limits human Th17 responses von Purvis, Harriet A, Anderson, Amy E, Young, David A, Isaacs, John D, Hilkens, Catharien M U

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Reduced TCR‐dependent activation through citrullination of a T‐cell epitope enhances Th17 development by disruption of the STAT3/5 balance von Tibbitt, Christopher, Falconer, Jane, Stoop, Jeroen, Eden, Willem, Robinson, John H., Hilkens, Catharien M.U.

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The choice of adjuvant determines the cytokine profile of T cells in proteoglycan‐induced arthritis but does not influence disease severity von Stoop, Jeroen N., Tibbitt, Christopher A., Eden, Willem, Robinson, John H., Hilkens, Catharien M. U.

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Emerging immunotherapies for rheumatoid arthritis von Reynolds, Gary, Cooles, Faye AH, Isaacs, John D, Hilkens, Catharien MU

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The interferon gene signature is increased in patients with early treatment-naive rheumatoid arthritis and predicts a poorer response to initial therapy von Cooles, Faye A.H., Anderson, Amy E., Lendrem, Dennis W., Norris, Julie, Pratt, Arthur G., Hilkens, Catharien M.U., Isaacs, John D.

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Inhibition of macropinocytosis blocks antigen presentation of type II collagen in vitro and in vivo in HLA-DR1 transgenic mice von von Delwig, Alexei, Hilkens, Catharien M U, Altmann, Daniel M, Holmdahl, Rikard, Isaacs, John D, Harding, Clifford V, Robertson, Helen, McKie, Norman, Robinson, John H

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Minimum information about tolerogenic antigen-presenting cells (MITAP): a first step towards reproducibility and standardisation of cellular therapies von Lord, Phillip, Spiering, Rachel, Aguillon, Juan C, Anderson, Amy E, Appel, Silke, Benitez-Ribas, Daniel, Ten Brinke, Anja, Broere, Femke, Cools, Nathalie, Cuturi, Maria Cristina, Diboll, Julie, Geissler, Edward K, Giannoukakis, Nick, Gregori, Silvia, van Ham, S Marieke, Lattimer, Staci, Marshall, Lindsay, Harry, Rachel A, Hutchinson, James A, Isaacs, John D, Joosten, Irma, van Kooten, Cees, Lopez Diaz de Cerio, Ascension, Nikolic, Tatjana, Oral, Haluk Barbaros, Sofronic-Milosavljevic, Ljiljana, Ritter, Thomas, Riquelme, Paloma, Thomson, Angus W, Trucco, Massimo, Vives-Pi, Marta, Martinez-Caceres, Eva M, Hilkens, Catharien M U

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Tolerogenic dendritic cells differentially modulate naïve and memory CD4+ T cells von Anderson, Amy E, Sayers, Bethan, Diboll, Julie, Isaacs, John D, Hilkens, Catharien MU

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OPTIMAL: An OPTimized Imaging Mass cytometry AnaLysis framework for benchmarking segmentation and data exploration von Hunter, Bethany, Nicorescu, Ioana, Foster, Emma, McDonald, David, Hulme, Gillian, Fuller, Andrew, Thomson, Amanda, Goldsborough, Thibaut, Hilkens, Catharien MU, Majo, Joaquim, Milross, Luke, Fisher, Andrew, Bankhead, Peter, Wills, John, Rees, Paul, Filby, Andrew, Merces, George

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Inhibition of macropinocytosis blocks antigen presentation of type II collagen in vitro and in vivoin HLA-DR1 transgenic mice von von Delwig, Alexei, Hilkens, Catharien MU, Altmann, Daniel M, Holmdahl, Rikard, Isaacs, John D, Harding, Clifford V, Robertson, Helen, McKie, Norman, Robinson, John H

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IRF4 transcription factor-dependent CD11b+ dendritic cells in human and mouse control mucosal IL-17 cytokine responses von Schlitzer, Andreas, McGovern, Naomi, Teo, Pearline, Zelante, Teresa, Atarashi, Koji, Low, Donovan, Ho, Adrian WS, See, Peter, Shin, Amanda, Wasan, Pavandip Singh, Hoeffel, Guillaume, Malleret, Benoit, Heiseke, Alexander, Chew, Samantha, Jardine, Laura, Purvis, Harriet A, Hilkens, Catharien MU, Tam, John, Poidinger, Michael, Stanley, E Richard, Krug, Anne B, Renia, Laurent, Sivasankar, Baalasubramanian, Ng, Lai Guan, Collin, Matthew, Ricciardi-Castagnoli, Paola, Honda, Kenya, Haniffa, Muzlifah, Ginhoux, Florent

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T-regulatory cells exhibit a biphasic response to prolonged endurance exercise in humans von Tom Clifford, Matthew J Wood, Philip Stocks, Glyn Howatson, Emma J Stevenson, Catharien MU Hilkens

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