IRF4 Transcription Factor-Dependent CD11b+ Dendritic Cells in Human and Mouse Control Mucosal IL-17 Cytokine Responses von Schlitzer, Andreas, McGovern, Naomi, Teo, Pearline, Zelante, Teresa, Atarashi, Koji, Low, Donovan, Ho, Adrian W.S., See, Peter, Shin, Amanda, Wasan, Pavandip Singh, Hoeffel, Guillaume, Malleret, Benoit, Heiseke, Alexander, Chew, Samantha, Jardine, Laura, Purvis, Harriet A., Hilkens, Catharien M.U., Tam, John, Poidinger, Michael, Stanley, E. Richard, Krug, Anne B., Renia, Laurent, Sivasankar, Baalasubramanian, Ng, Lai Guan, Collin, Matthew, Ricciardi-Castagnoli, Paola, Honda, Kenya, Haniffa, Muzlifah, Ginhoux, Florent

Volltext

Synovial Macrophages in Osteoarthritis: The Key to Understanding Pathogenesis? von Thomson, Amanda, Hilkens, Catharien M. U.

Volltext

β2 Integrins As Regulators of Dendritic Cell, Monocyte, and Macrophage Function von Schittenhelm, Leonie, Hilkens, Catharien M., Morrison, Vicky L.

Volltext

Adult Human Fibroblasts Are Potent Immunoregulatory Cells and Functionally Equivalent to Mesenchymal Stem Cells von Haniffa, Muzlifah A, Wang, Xiao-Nong, Holtick, Udo, Rae, Michelle, Isaacs, John D, Dickinson, Anne M, Hilkens, Catharien M. U, Collin, Matthew P

Volltext

Generation and characterisation of therapeutic tolerogenic dendritic cells for rheumatoid arthritis von Harry, Rachel A, Anderson, Amy E, Isaacs, John D, Hilkens, Catharien M U

Volltext

Effective Endotoxin Removal from Chitosan That Preserves Chemical Structure and Improves Compatibility with Immune Cells von Reay, Sophie L, Jackson, Emma L, Salthouse, Daniel, Ferreira, Ana Marina, Hilkens, Catharien M U, Novakovic, Katarina

Volltext

Dendritic cell maturation and survival are differentially regulated by TNFR1 and TNFR2 von Maney, Nicola J, Reynolds, Gary, Krippner-Heidenreich, Anja, Hilkens, Catharien M U

Volltext

T-regulatory cells exhibit a biphasic response to prolonged endurance exercise in humans von Clifford, Tom, Wood, Matthew J., Stocks, Philip, Howatson, Glyn, Stevenson, Emma J., Hilkens, Catharien M. U.

Volltext

Therapeutic effect of tolerogenic dendritic cells in established collagen‐induced arthritis is associated with a reduction in Th17 responses von Stoop, Jeroen N., Harry, Rachel A., von Delwig, Alexei, Isaacs, John D., Robinson, John H., Hilkens, Catharien M. U.

Volltext

Targeting of tolerogenic dendritic cells to heat-shock proteins in inflammatory arthritis von Spiering, Rachel, Jansen, Manon A A, Wood, Matthew J, Fath, Anshorulloh A, Eltherington, Oliver, Anderson, Amy E, Pratt, Arthur G, van Eden, Willem, Isaacs, John D, Broere, Femke, Hilkens, Catharien M U

Volltext

Low-strength T-cell activation promotes Th17 responses von Purvis, Harriet A., Stoop, Jeroen N., Mann, Jelena, Woods, Steven, Kozijn, Anne E., Hambleton, Sophie, Robinson, John H., Isaacs, John D., Anderson, Amy E., Hilkens, Catharien M.U.

Volltext

A negative feedback loop mediated by STAT3 limits human Th17 responses von Purvis, Harriet A, Anderson, Amy E, Young, David A, Isaacs, John D, Hilkens, Catharien M U

Volltext

Interplay between biomaterials and the immune system: Challenges and opportunities in regenerative medicine von Salthouse, Daniel, Novakovic, Katarina, Hilkens, Catharien M.U., Ferreira, Ana Marina

Volltext

A CD4 T cell gene signature for early rheumatoid arthritis implicates interleukin 6-mediated STAT3 signalling, particularly in anti-citrullinated peptide antibody-negative disease von Pratt, Arthur G, Swan, Daniel C, Richardson, Sarah, Wilson, Gillian, Hilkens, Catharien M U, Young, David A, Isaacs, John D

Volltext

OPTIMAL: An OPTimized Imaging Mass cytometry AnaLysis framework for benchmarking segmentation and data exploration von Hunter, Bethany, Nicorescu, Ioana, Foster, Emma, McDonald, David, Hulme, Gillian, Fuller, Andrew, Thomson, Amanda, Goldsborough, Thibaut, Hilkens, Catharien M. U., Majo, Joaquim, Milross, Luke, Fisher, Andrew, Bankhead, Peter, Wills, John, Rees, Paul, Filby, Andrew, Merces, George

Volltext

Developing tolerogenic dendritic cell therapy for rheumatoid arthritis: what can we learn from mouse models? von Stoop, Jeroen N, Robinson, John H, Hilkens, Catharien M U

Volltext

The interferon gene signature is increased in patients with early treatment-naive rheumatoid arthritis and predicts a poorer response to initial therapy von Cooles, Faye A.H., Anderson, Amy E., Lendrem, Dennis W., Norris, Julie, Pratt, Arthur G., Hilkens, Catharien M.U., Isaacs, John D.

Volltext

LPS activation is required for migratory activity and antigen presentation by tolerogenic dendritic cells von Anderson, Amy E., Swan, David J., Sayers, Bethan L., Harry, Rachel A., Patterson, Angela M., Delwig, Alexei, Robinson, John H., Isaacs, John D., Hilkens, Catharien M. U.

Volltext

Ways Forward for Tolerance-Inducing Cellular Therapies- an AFACTT Perspective von Ten Brinke, Anja, Martinez-Llordella, Marc, Cools, Nathalie, Hilkens, Catharien M U, van Ham, S Marieke, Sawitzki, Birgit, Geissler, Edward K, Lombardi, Giovanna, Trzonkowski, Piotr, Martinez-Caceres, Eva

Volltext

Matured Tolerogenic Dendritic Cells Effectively Inhibit Autoantigen Specific CD4 + T Cells in a Murine Arthritis Model von Jansen, Manon A A, Spiering, Rachel, Ludwig, Irene S, van Eden, Willem, Hilkens, Catharien M U, Broere, Femke

Volltext