Novel hyaluronic acid-methotrexate conjugate suppresses joint inflammation in the rat knee: efficacy and safety evaluation in two rat arthritis models von Tamura, Tatsuya, Higuchi, Yoshinobu, Kitamura, Hidetomo, Murao, Naoaki, Saitoh, Ryoichi, Morikawa, Tadashi, Sato, Haruhiko

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Engineered monoclonal antibody with novel antigen-sweeping activity in vivo von Igawa, Tomoyuki, Maeda, Atsuhiko, Haraya, Kenta, Tachibana, Tatsuhiko, Iwayanagi, Yuki, Mimoto, Futa, Higuchi, Yoshinobu, Ishii, Shinya, Tamba, Shigero, Hironiwa, Naoka, Nagano, Kozue, Wakabayashi, Tetsuya, Tsunoda, Hiroyuki, Hattori, Kunihiro

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Cynomolgus monkey model of interleukin‐31‐induced scratching depicts blockade of human interleukin‐31 receptor A by a humanized monoclonal antibody von Oyama, Sohei, Kitamura, Hidetomo, Kuramochi, Taichi, Higuchi, Yoshinobu, Matsushita, Hiroaki, Suzuki, Tsukasa, Goto, Masaaki, Adachi, Hideki, Kasutani, Keiko, Sakamoto, Akihisa, Iwayanagi, Yuki, Kaneko, Akihisa, Nanami, Masahiko, Fujii, Etsuko, Esaki, Keiko, Takashima, Yoshiaki, Shimaoka, Shin, Hattori, Kunihiro, Kawabe, Yoshiki

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Novel genetically-humanized mouse model established to evaluate efficacy of therapeutic agents to human interleukin-6 receptor von Ueda, Otoya, Tateishi, Hiromi, Higuchi, Yoshinobu, Fujii, Etsuko, Kato, Atsuhiko, Kawase, Yosuke, Wada, Naoko A., Tachibe, Takanori, Kakefuda, Mami, Goto, Chisato, Kawaharada, Makoto, Shimaoka, Shin, Hattori, Kunihiro, Jishage, Kou-ichi

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Alfacalcidol Inhibits Bone Resorption and Stimulates Formation in an Ovariectomized Rat Model of Osteoporosis: Distinct Actions from Estrogen von Shiraishi, Ayako, Takeda, Satoshi, Masaki, Toshimi, Higuchi, Yoshinobu, Uchiyama, Yasushi, Kubodera, Noboru, Sato, Katsuhiko, Ikeda, Kyoji, Nakamura, Toshitaka, Matsumoto, Toshio, Ogata, Etsuro

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Induction of Osteogenic Differentiation by Hedgehog Proteins von Nakamura, Takashi, Aikawa, Tomonao, Iwamoto-Enomoto, Motomi, Iwamoto, Masahiro, Higuchi, Yoshinobu, Maurizio, Pacifici, Kinto, Naoki, Yamaguchi, Akira, Noji, Sumihare, Kurisu, Kojiro, Matsuya, Tokuzo

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Bone Morphogenetic Protein Signaling Is Required for Maintenance of Differentiated Phenotype, Control of Proliferation, and Hypertrophy in Chondrocytes von Enomoto-Iwamoto, Motomi, Iwamoto, Masahiro, Mukudai, Yoshiki, Kawakami, Yasuhiko, Nohno, Tsutomu, Higuchi, Yoshinobu, Takemoto, Seiji, Ohuchi, Hideyo, Noji, Sumihare, Kurisu, Kojiro

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The Effects of Interleukin-6 Signal Blockade on Immune System, Reproductive and Skeletal Development in Juvenile Mice von Sakurai, Takayuki, Takai, Ryo, Bürgin, Heinrich, Shioda, Akifumi, Sakamoto, Yuichiro, Amano, Jun, Grimm, Hans Peter, Richter, Wolfgang F., Higuchi, Yoshinobu, Chiba, Shuichi, Kawamura, Akinori, Suzuki, Masami, Müller, Lutz

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IL-6 plays an essential role in neutrophilia under inflammation von Hashizume, Misato, Higuchi, Yoshinobu, Uchiyama, Yasushi, Mihara, Masahiko

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Antibody recycling by engineered pH-dependent antigen binding improves the duration of antigen neutralization von Igawa, Tomoyuki, Ishii, Shinya, Tachibana, Tatsuhiko, Maeda, Atsuhiko, Higuchi, Yoshinobu, Shimaoka, Shin, Moriyama, Chifumi, Watanabe, Tomoyuki, Takubo, Ryoko, Doi, Yoshiaki, Wakabayashi, Tetsuya, Hayasaka, Akira, Kadono, Shoujiro, Miyazaki, Takuya, Haraya, Kenta, Sekimori, Yasuo, Kojima, Tetsuo, Nabuchi, Yoshiaki, Aso, Yoshinori, Kawabe, Yoshiki, Hattori, Kunihiro

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Transcription Factor ERG Variants and Functional Diversification of Chondrocytes during Limb Long Bone Development von Iwamoto, Masahiro, Higuchi, Yoshinobu, Koyama, Eiki, Enomoto-Iwamoto, Motomi, Kurisu, Kojiro, Yeh, Helena, Abrams, William R., Rosenbloom, Joel, Pacifici, Maurizio

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Hedgehog Proteins Stimulate Chondrogenic Cell Differentiation and Cartilage Formation von Enomoto‐Iwamoto, Motomi, Nakamura, Takashi, Aikawa, Tomonao, Higuchi, Yoshinobu, Yuasa, Takahito, Yamaguchi, Akira, Nohno, Tsutomu, Noji, Sumihare, Matsuya, Tokuzo, Kurisu, Kojiro, Koyama, Eiki, Pacifici, Maurizio, Iwamoto, Masahiro

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Erratum to: Novel hyaluronic acid-methotrexate conjugate suppresses joint inflammation in the rat knee: efficacy and safety evaluation in two rat arthritis models von Tamura, Tatsuya, Higuchi, Yoshinobu, Kitamura, Hidetomo, Murao, Naoaki, Saitoh, Ryoichi, Morikawa, Tadashi, Sato, Haruhiko

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Novel hyaluronic acid–methotrexate conjugates for osteoarthritis treatment von Homma, Akie, Sato, Haruhiko, Okamachi, Akira, Emura, Takashi, Ishizawa, Takenori, Kato, Tatsuya, Matsuura, Tetsu, Sato, Shigeo, Tamura, Tatsuya, Higuchi, Yoshinobu, Watanabe, Tomoyuki, Kitamura, Hidetomo, Asanuma, Kentaro, Yamazaki, Tadao, Ikemi, Masahisa, Kitagawa, Hironoshin, Morikawa, Tadashi, Ikeya, Hitoshi, Maeda, Kazuaki, Takahashi, Koichi, Nohmi, Kenji, Izutani, Noriyuki, Kanda, Makoto, Suzuki, Ryochi

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Synthesis and optimization of hyaluronic acid–methotrexate conjugates to maximize benefit in the treatment of osteoarthritis von Homma, Akie, Sato, Haruhiko, Tamura, Tatsuya, Okamachi, Akira, Emura, Takashi, Ishizawa, Takenori, Kato, Tatsuya, Matsuura, Tetsu, Sato, Shigeo, Higuchi, Yoshinobu, Watanabe, Tomoyuki, Kitamura, Hidetomo, Asanuma, Kentaro, Yamazaki, Tadao, Ikemi, Masahisa, Kitagawa, Hironoshin, Morikawa, Tadashi, Ikeya, Hitoshi, Maeda, Kazuaki, Takahashi, Koichi, Nohmi, Kenji, Izutani, Noriyuki, Kanda, Makoto, Suzuki, Ryohchi

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6 plays an essential role in neutrophilia under inflammation von Hashizume, Misato, Higuchi, Yoshinobu, Uchiyama, Yasushi, Mihara, Masahiko

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The Effects of Interleukin-6 Signal Blockade on Fertility, Embryo-fetal Development, and Immunization In vivo von Sakurai, Takayuki, Takai, Ryo, Bürgin, Heinrich, Ishihara, Kana, Sakamoto, Yuichiro, Amano, Jun, Higuchi, Yoshinobu, Chiba, Shuichi, Singer, Thomas, Kawamura, Akinori, Suzuki, Masami, Müller, Lutz

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FRACTIONAL FUNDS TRANSFER/ACCUMULATION DEVICE, PROGRAM, AND METHOD von TANAKA, TATSUO, HIGUCHI, YOSHINOBU

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FRACTIONAL FUNDS TRANSFER/ACCUMULATION DEVICE, PROGRAM, AND METHOD von TANAKA, TATSUO, HIGUCHI, YOSHINOBU

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FRACTIONAL FUNDS TRANSFER/ACCUMULATION DEVICE, PROGRAM, AND METHOD von TANAKA, TATSUO, HIGUCHI, YOSHINOBU

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