421 A retrospective review of the phenotypes of older UK adult cystic fibrosis patients homozygous for the F508del mutation von Ewence, A.E, Milne, S, Higton, A, Orchard, C

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246 Musculoskeletal symptoms in a cystic fibrosis population von Narang, R, Higton, A, Orchard, C, Lloyd, M

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Investigation and management of lung cancer in older adults von Higton, A.M, Monach, J, Congleton, J

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302 A retrospective review of renal function and intravenous (IV) antibiotic use in an adult UK cystic fibrosis centre von Ewence, A.E, Malone, S, Nutbourne, A, Higton, A, Orchard, C

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57 Does the inclusion of MRI brain as part of the lung cancer staging pathway identify patients with asymptomatic brain metastases: avoiding inappropriate radical treatment? von Eruchie, D, Ewence, A, Higton, A, Macintyre, J, Illsley, M, Hughes, N

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Beware the pregnant woman with breathlessness von Higton, A, Whale, C, Musk, M, Gabbay, E

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Pulmonary hypertension in pregnancy: two cases and review of the literature von Higton, A. M., Whale, C., Musk, M., Gabbay, E.

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P220 Starting Symkevi for all eligible patients within 30 days of NHS England’s funding announcement: dedicated Symkevi initiation clinic von Cunningham, J., Orchard, C., Higton, A.

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P244 The impact of CFTR modulators on positive Pseudomonas aeruginosa (Pa) culture and antibiotic susceptibility in adults with cystic fibrosis von Ellis, N., Cunningham, J., O’Dowd, D., Garner, D., Orchard, C., Ewence, A., Higton, A., Lillis, A.

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P324 Changes to the dietetic landscape in a UK adult cystic fibrosis centre following the introduction of triple CFTR modulator therapy and continuous glucose monitoring to screen... von Bradshaw, C., Cunningham, J., Kettley, C., Duguid, J., Cudiamat, E., Santos, L., Orchard, C., Ewence, A., Lillis, A., Higton, A.

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EPS5.09 Optimising vitamin D status in cystic fibrosis patients: changes over a ten year period in a United Kingdom adult cystic fibrosis centre von Kettley, C., Cunningham, J., Bradshaw, C., Duguid, J., Cudiamat, E., Santos, L., Orchard, C., Ewence, A., Lillis, A., Higton, A.

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122: The Relationship between Positive HLA Antibodies, Acute Rejection Episodes and Lung Function Decline Following Lung Transplantation von Whale, C.I, Higton, A, Fernandez, N, Lawrence, S, Jary, C, Gabbay, E, Musk, M

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Factors associated with clinical progression to severe COVID-19 in people with cystic fibrosis: A global observational study von Carr, Siobhán B, McClenaghan, Elliot, Elbert, Alexander, Faro, Albert, Cosgriff, Rebecca, Abdrakhmanov, Olzhas, Brownlee, Keith, Byrnes, Catherine A, Cheng, Stephanie Y, Colombo, Carla, Goss, Christopher H, Gulmans, Vincent, Harutyunyan, Satenik, Helmick, Meagan, McKone, Edward, Melo, Joel, Middleton, Peter G, Mondejar-Lopez, Pedro, de Monestrol, Isabelle, Nährlich, Lutz, Padoan, Rita, Pastor-Vivero, M Dolores, Rizvi, Samar, Ruseckaite, Rasa, Salvatore, Marco, da Silva-Filho, Luiz Vicente R F, Marshall, Bruce C, Bell, Scott C, Reid, David, Wark, Peter, Van Braeckel, Eva, Gohy, Sophie, Knoop, Christiane, De Wachter, Elke, Dupont, Lieven, Hanssens, Laurence, Nowé, Vicky, Lequesne, Monique, Athanazio, Rodrigo A, Meneses, Daniela G, Boussaud, Véronique, Brinchault, Graziella, Coirier-Duet, Emmanuelle, Dubus, Jean-Christophe, de Miranda, Sandra, Beaumont, Laurence, Kanaan, Reem, Lauraens, Muriel, Martin, Clémence, Mittaine, Marie, Prévotat, Anne, Sermet-Gaudelus, Isabelle, Tatopoulos, Aurelie, Chiron, Raphael, Dalphin, Marie-Laure, Gerardin, Michele, Plant, Barry, Gunaratnam, Cedric, Jackson, Abaigeal, Luijk, Bart, Wesseling, Geertjan, Zhekayte, Elena, Amelina, Elena, Mukhina, Mariya, Simonova, Olga, Sole-Jover, Amparo, Cortell-Aznar, Isidoro, Girón-Moreno, Rosa, López-Neyra, Alejandro, Lázaro-Carrasco, Maite, Vivero, Dolores Pastor, Prados-Sanchez, Concepción, Costa-Colomer, Jordi, Lindberg, Ulrika, Diemer, Stefanie, Bourke, Stephen J, Charman, Susan C, Collinson, Janet, Denniston, Sarah, Duckers, Jamie, Gunn, Elaine, Higton, Alex, Ho, Timothy, Hull, Jeremy, Jones, Andrew, Ketchell, Robert Ian, Madge, Susan L., Maitra, Anirban, Mujtaba, Ghulam, Nash, Edward, O'Brien, Christopher, Onyon, Claire, Orchard, Christopher, Rodgers, Helen, Shafi, Nadia, Simmonds, Nicholas, Walshaw, Martin, Orenti, Annalisa, Elnazir, Basil, Cox, Des

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P199 Assessing the effectiveness of a six-month partially supervised outpatient exercise programme for adults with cystic fibrosis: a service evaluation von Banks, A., Bozic, H., Choudhary, A., Horobin, H., Johnson, L., Saunders, J., Orchard, C., Higton, A.

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Does endobronchial ultrasound (EBUS) fine needle aspirate provide sufficient tissue for molecular markers? von Gabriel, L., Brackenborough, K., Higton, A., Hughes, N., Macintyre, J., Powell, H.

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Do junior doctors take sick leave? von Perkin, M R, Higton, A, Witcomb, M

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P181 The effects of linagliptin in patients with a diagnosis of Cystic Fibrosis-Related Diabetes von Cunningham, J., Bradshaw, C., Damani, A., Kettley, C., Duguid, J., Cudiamat, E., Santos, L., Billings, L., Henke, C., Higton, A., Orchard, C., Samarasinghe, Y.

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Idiopathic inflammatory myositis-associated interstitial lung disease: ethnicity differences and lung function trends in a British cohort von CHUA, Felix, HIGTON, Alexandra M, COLEBATCH, Alexandra N, O'REILLY, Katherine, GRUBNIC, Sisa, VLAHOS, Ioannis, EDWARDS, Christopher J, KIELY, Patrick D. W

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B38 UPDATE IN ADULT CYSTIC FIBROSIS: Does Ivacaftor Lead To Reduced Spending On Antibiotics And Frequency Of Acute Exacerbations In Cystic Fibrosis (cf) Patients? The Experience Of... von Ewence, A E, Eruchie, C N, Higton, A M, Ho, T B L

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B103 DIE ANOTHER DAY: WHAT WE ARE LEARNING ABOUT HOW TO TREAT AND BEAT LUNG CANCER: Chronic Obstructive Pulmonary Disease (COPD) Prevalence In Patients Diagnosed With Lung Cancer:... von Ewence, A E, Higton, A M, MacIntyre, J D, Ho, T B, Seymour, J M

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