Interferon and biologic signatures in dermatomyositis skin: specificity and heterogeneity across diseases von Wong, David, Kea, Bory, Pesich, Rob, Higgs, Brandon W, Zhu, Wei, Brown, Patrick, Yao, Yihong, Fiorentino, David

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Genomic Landscape Survey Identifies SRSF1 as a Key Oncodriver in Small Cell Lung Cancer von Jiang, Liyan, Huang, Jiaqi, Higgs, Brandon W, Hu, Zhibin, Xiao, Zhan, Yao, Xin, Conley, Sarah, Zhong, Haihong, Liu, Zheng, Brohawn, Philip, Shen, Dong, Wu, Song, Ge, Xiaoxiao, Jiang, Yue, Zhao, Yizhuo, Lou, Yuqing, Morehouse, Chris, Zhu, Wei, Sebastian, Yinong, Czapiga, Meggan, Oganesyan, Vaheh, Fu, Haihua, Niu, Yanjie, Zhang, Wei, Streicher, Katie, Tice, David, Zhao, Heng, Zhu, Meng, Xu, Lin, Herbst, Ronald, Su, Xinying, Gu, Yi, Li, Shyoung, Huang, Lihua, Gu, Jianren, Han, Baohui, Jallal, Bahija, Shen, Hongbing, Yao, Yihong

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A Blood-based Assay for Assessment of Tumor Mutational Burden in First-line Metastatic NSCLC Treatment: Results from the MYSTIC Study von Si, Han, Kuziora, Michael, Quinn, Katie J, Helman, Elena, Ye, Jiabu, Liu, Feng, Scheuring, Urban, Peters, Solange, Rizvi, Naiyer A, Brohawn, Philip Z, Ranade, Koustubh, Higgs, Brandon W, Banks, Kimberly C, Chand, Vikram K, Raja, Rajiv

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A novel oncogenic role for the miRNA-506-514 cluster in initiating melanocyte transformation and promoting melanoma growth von Streicher, K L, Zhu, W, Lehmann, K P, Georgantas, R W, Morehouse, C A, Brohawn, P, Carrasco, R A, Xiao, Z, Tice, D A, Higgs, B W, Richman, L, Jallal, B, Ranade, K, Yao, Y

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Inhibition of Myogenic MicroRNAs 1, 133, and 206 by Inflammatory Cytokines Links Inflammation and Muscle Degeneration in Adult Inflammatory Myopathies von Georgantas, Robert W., Streicher, Katie, Greenberg, Steven A., Greenlees, Lydia M., Zhu, Wei, Brohawn, Philip Z., Higgs, Brandon W., Czapiga, Meggan, Morehouse, Christopher A., Amato, Anthony, Richman, Laura, Jallal, Bahija, Yao, Yihong, Ranade, Koustubh

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In Vivo Therapeutic Success of MicroRNA‐155 Antagomir in a Mouse Model of Lupus Alveolar Hemorrhage von Zhou, Shiyu, Wang, Yan, Meng, Yao, Xiao, Chunyuan, Liu, Zheng, Brohawn, Philip, Higgs, Brandon W., Jallal, Bahija, Jia, Qian, Qu, Bo, Huang, Xinfang, Tang, Yuanjia, Yao, Yihong, Harley, John B., Shen, Nan

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Patients with systemic lupus erythematosus, myositis, rheumatoid arthritis and scleroderma share activation of a common type I interferon pathway von Higgs, Brandon W, Liu, Zheng, White, Barbara, Zhu, Wei, White, Wendy I, Morehouse, Chris, Brohawn, Philip, Kiener, Peter A, Richman, Laura, Fiorentino, David, Greenberg, Steven A, Jallal, Bahija, Yao, Yihong

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High-throughput mediation analysis of human proteome and metabolome identifies mediators of post-bariatric surgical diabetes control von Dreyfuss, Jonathan M., Yuchi, Yixing, Dong, Xuehong, Efthymiou, Vissarion, Pan, Hui, Simonson, Donald C., Vernon, Ashley, Halperin, Florencia, Aryal, Pratik, Konkar, Anish, Sebastian, Yinong, Higgs, Brandon W., Grimsby, Joseph, Rondinone, Cristina M., Kasif, Simon, Kahn, Barbara B., Foster, Kathleen, Seeley, Randy, Goldfine, Allison, Djordjilović, Vera, Patti, Mary Elizabeth

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The Role of ARF6 in Biliary Atresia von Ningappa, Mylarappa, So, Juhoon, Glessner, Joseph, Ashokkumar, Chethan, Ranganathan, Sarangarajan, Min, Jun, Higgs, Brandon W, Sun, Qing, Haberman, Kimberly, Schmitt, Lori, Vilarinho, Silvia, Mistry, Pramod K, Vockley, Gerard, Dhawan, Anil, Gittes, George K, Hakonarson, Hakon, Jaffe, Ronald, Subramaniam, Shankar, Shin, Donghun, Sindhi, Rakesh

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Automated image analysis of NSCLC biopsies to predict response to anti-PD-L1 therapy von Althammer, Sonja, Tan, Tze Heng, Spitzmüller, Andreas, Rognoni, Lorenz, Wiestler, Tobias, Herz, Thomas, Widmaier, Moritz, Rebelatto, Marlon C, Kaplon, Helene, Damotte, Diane, Alifano, Marco, Hammond, Scott A, Dieu-Nosjean, Marie-Caroline, Ranade, Koustubh, Schmidt, Guenter, Higgs, Brandon W, Steele, Keith E

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Fracture toughness of bovine bone: influence of orientation and storage media von Lucksanasombool, P, Higgs, W.A.J, Higgs, R.J.E.D, Swain, M.V

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Relationship between disease activity and type 1 interferon- and other cytokine-inducible gene expression in blood in dermatomyositis and polymyositis von Greenberg, S A, Higgs, B W, Morehouse, C, Walsh, R J, Won Kong, S, Brohawn, P, Zhu, W, Amato, A, Salajegheh, M, White, B, Kiener, P A, Jallal, B, Yao, Y

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Altered expression of insulin receptor isoforms in breast cancer von Huang, Jiaqi, Morehouse, Chris, Streicher, Katie, Higgs, Brandon W, Gao, Jin, Czapiga, Meggan, Boutrin, Anmarie, Zhu, Wei, Brohawn, Philip, Chang, Yong, Viner, Jaye, LaVallee, Theresa, Richman, Laura, Jallal, Bahija, Yao, Yihong

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Use of type I interferon-inducible mRNAs as pharmacodynamic markers and potential diagnostic markers in trials with sifalimumab, an anti-IFNα antibody, in systemic lupus erythemato... von Yao, Yihong, Higgs, Brandon W, Richman, Laura, White, Barbara, Jallal, Bahija

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Early Reduction in ctDNA Predicts Survival in Patients with Lung and Bladder Cancer Treated with Durvalumab von Raja, Rajiv, Kuziora, Michael, Brohawn, Philip Z, Higgs, Brandon W, Gupta, Ashok, Dennis, Phillip A, Ranade, Koustubh

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Interferon Gamma Messenger RNA Signature in Tumor Biopsies Predicts Outcomes in Patients with Non-Small Cell Lung Carcinoma or Urothelial Cancer Treated with Durvalumab von Higgs, Brandon W, Morehouse, Christopher A, Streicher, Katie, Brohawn, Philip Z, Pilataxi, Fernanda, Gupta, Ashok, Ranade, Koustubh

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MicroRNA-206 induces G1 arrest in melanoma by inhibition of CDK4 and Cyclin D von Georgantas III, Robert W., Streicher, Katie, Luo, Xiaobing, Greenlees, Lydia, Zhu, Wei, Liu, Zheng, Brohawn, Philip, Morehouse, Christopher, Higgs, Brandon W., Richman, Laura, Jallal, Bahija, Yao, Yihong, Ranade, Koustubh

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Low-frequency coding variants at 6p21.33 and 20q11.21 are associated with lung cancer risk in Chinese populations von Jin, Guangfu, Zhu, Meng, Yin, Rong, Shen, Wei, Liu, Jia, Sun, Jie, Wang, Cheng, Dai, Juncheng, Ma, Hongxia, Wu, Chen, Yin, Zhihua, Huang, Jiaqi, Higgs, Brandon W., Xu, Lin, Yao, Yihong, Christiani, David C., Amos, Christopher I., Hu, Zhibin, Zhou, Baosen, Shi, Yongyong, Lin, Dongxin, Shen, Hongbing

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Pharmacogenomics and Translational Simulations to Bridge Indications for an Anti-Interferon-α Receptor Antibody von Wang, B, Higgs, B W, Chang, L, Vainshtein, I, Liu, Z, Streicher, K, Liang, M, White, W I, Yoo, S, Richman, L, Jallal, B, Roskos, L, Yao, Y

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The Combiome Hypothesis: Selecting Optimal Treatment for Cancer Patients von Hirsch, Fred R., Walker, Jill, Higgs, Brandon W., Cooper, Zachary A., Raja, Rajiv G., Wistuba, Ignacio I.

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