STING pathway agonism as a cancer therapeutic von Flood, Blake A., Higgs, Emily F., Li, Shuyin, Luke, Jason J., Gajewski, Thomas F.

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Tumor heterogeneity and clonal cooperation influence the immune selection of IFN-γ-signaling mutant cancer cells von Williams, Jason B., Li, Shuyin, Higgs, Emily F., Cabanov, Alexandra, Wang, Xiaozhong, Huang, Haochu, Gajewski, Thomas F.

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Immune cell and tumor cell-derived CXCL10 is indicative of immunotherapy response in metastatic melanoma von Reschke, Robin, Yu, Jovian, Flood, Blake A, Higgs, Emily F, Hatogai, Ken, Gajewski, Thomas F

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Batf3+ DCs and the 4-1BB/4-1BBL axis are required at the effector phase in the tumor microenvironment for PD-1/PD-L1 blockade efficacy von Ziblat, Andrea, Horton, Brendan L., Higgs, Emily F., Hatogai, Ken, Martinez, Anna, Shapiro, Jason W., Kim, Danny E.C., Zha, YuanYuan, Sweis, Randy F., Gajewski, Thomas F.

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Wilms tumor reveals DNA repair gene hyperexpression is linked to lack of tumor immune infiltration von Higgs, Emily F, Bao, Riyue, Hatogai, Ken, Gajewski, Thomas F

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Dendritic cell-intrinsic PTPN22 negatively regulates antitumor immunity and impacts anti-PD-L1 efficacy von Acero-Bedoya, Santiago, Higgs, Emily F, Martinez, Anna C, Tonea, Ruxandra, Gajewski, Thomas F

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Immunotherapy with a sting von Gajewski, Thomas F, Higgs, Emily F

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COVIDOSE: A Phase II Clinical Trial of Low‐Dose Tocilizumab in the Treatment of Noncritical COVID‐19 Pneumonia von Strohbehn, Garth W., Heiss, Brian L., Rouhani, Sherin J., Trujillo, Jonathan A., Yu, Jovian, Kacew, Alec J., Higgs, Emily F., Bloodworth, Jeffrey C., Cabanov, Alexandra, Wright, Rachel C., Koziol, Adriana K., Weiss, Alexandra, Danahey, Keith, Karrison, Theodore G., Edens, Cuoghi C., Bauer Ventura, Iazsmin, Pettit, Natasha N., Patel, Bhakti K., Pisano, Jennifer, Strek, Mary E., Gajewski, Thomas F., Ratain, Mark J., Reid, Pankti D.

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Insights from a Rapidly Implemented COVID-19 Biobank Using Electronic Consent and Informatics Tools von Higgs, Emily F, Flood, Blake A, Pyzer, Athalia R, Rouhani, Sherin J, Trujillo, Jonathan A, Gajewski, Thomas F

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Abstract 2100: Dendritic cell-intrinsic PTPN22 negatively regulates anti-tumor immunity von Acero-Bedoya, Santiago, Higgs, Emily F., Gajewski, Thomas F.

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Abstract PO-067: Tissue banking from patients with SARS-CoV-2 (COVID-19) infection von Higgs, Emily F., Flood, Blake A., Pyzer, Athalia R., Rouhani, Sherin J., Trujillo, Jonathan A., Cron, Kyle R., Cabanov, Alexandra, Fessler, Jessica, Bloodworth, Jeffrey, Beavis, Kathleen, Yeo, Kiang-Teck J, Sweis, Randy F., Zha, Yuanyuan, Gajewski, Thomas F.

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Abstract S04-02: Treatment with tocilizumab does not inhibit induction of anti-COVID-19 antibodies in patients with severe SARS-CoV-2 infection von Cabanov, Alexandra, Flood, Blake A., Bloodworth, Jeffrey, Higgs, Emily F., Fessler, Jessica, Leung, Michael Y.K., Cron, Kyle R., Trujillo, Jonathan, Pyzer, Athalia R., Rouhani, Sherin, Strohbehn, Garth, Heiss, Brian, Ratain, Mark, Reid, Pankti, Yeo, Kiang-Teck J., Sweis, Randy F., Zha, Yuanyuan, Gajewski, Thomas F.

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Why the Stall? Using metabolomics to define the lack of upstream movement of invasive bigheaded carp in the Illinois River von Curtis-Quick, Jocelyn A, Ulanov, Alexander V, Li, Zhong, Bieber, John F, Tucker-Retter, Emily K, Suski, Cory D

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Pembrolizumab Plus Ipilimumab Following Anti-PD-1/L1 Failure in Melanoma von Olson, Daniel J, Eroglu, Zeynep, Brockstein, Bruce, Poklepovic, Andrew S, Bajaj, Madhuri, Babu, Sunil, Hallmeyer, Sigrun, Velasco, Mario, Lutzky, Jose, Higgs, Emily, Bao, Riyue, Carll, Timothy C, Labadie, Brian, Krausz, Thomas, Zha, Yuanyuan, Karrison, Theodore, Sondak, Vernon K, Gajewski, Thomas F, Khushalani, Nikhil I, Luke, Jason J

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Remdesivir for the Treatment of Covid-19 — Final Report von Beigel, John H, Tomashek, Kay M, Dodd, Lori E, Mehta, Aneesh K, Zingman, Barry S, Kalil, Andre C, Hohmann, Elizabeth, Chu, Helen Y, Luetkemeyer, Annie, Kline, Susan, Lopez de Castilla, Diego, Finberg, Robert W, Dierberg, Kerry, Tapson, Victor, Hsieh, Lanny, Patterson, Thomas F, Paredes, Roger, Sweeney, Daniel A, Short, William R, Touloumi, Giota, Lye, David Chien, Ohmagari, Norio, Oh, Myoung-don, Ruiz-Palacios, Guillermo M, Benfield, Thomas, Fätkenheuer, Gerd, Kortepeter, Mark G, Atmar, Robert L, Creech, C. Buddy, Lundgren, Jens, Babiker, Abdel G, Pett, Sarah, Neaton, James D, Burgess, Timothy H, Bonnett, Tyler, Green, Michelle, Makowski, Mat, Osinusi, Anu, Nayak, Seema, Lane, H. Clifford

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Efficacy and safety of two neutralising monoclonal antibody therapies, sotrovimab and BRII-196 plus BRII-198, for adults hospitalised with COVID-19 (TICO): a randomised controlled... von Vock, David M., Vekstein, Andrew, Der, Tatyana, Filbin, Michael R., Rice, Todd W., Casey, Jonathan D., Sharifpour, Milad, Bakowska, Elizieta, Kowalska, Justyna, Hite, R. Duncan, Jain, Mamta K., Grandits, Greg, Polizzotto, Mark N., Jundgren, Jens D., Smolskis, Mary C., Voge, Susan E., McNay, Laura A., Cahill, Kelly, Kirchoff, Matthew, Mock, Rebecca, Zuckerman, Judith, Amos, Laura, Carter, Anita, Thompson, Greg, Marks, Mary E., Want, Samantha, Clariday, Laura, Fisher, Tammy, Palacious, Adriana, Whitacre, Heather, Bouffler, Andrew, Pappers, Brian, Preamble, Katarina, Bartolo, Elizabeth Berry, Baio, Kim T., Maton, Missy, Hutcheon, Douglass, Sher, Linda, Sharma, Aniket, Rodina, Valentina, Kadl, Alexandra, Fox, Ashley, Nossaman, Bobby, Laudun, Sylvia, Broussard, Shane, Rabin, Joseph, Saharia, Kapil, Shipman, Samantha, Parr, Doug, Bokhart, Gordon, Eichman, Sharon M., Ringwood, Nancy, Kardos, Cynthia, Talmor, Daniel, Banner-Goodspeed, Valerie, Peacock, Rebekah K., Yee, Kimberly J., Garcia, Rebekah L., Perez, Cynthia, McSparron, Jake I., Co, Ivan N., Wiedemann, Herbert P., More, Harshada, Roads, Tammy, Miller, Chadwick, Dhar, Sanjay, Johnson, Jakea, Gray, Christopher, Hays, Margaret, Vjecha, Michael, Petersen, Tianna, Gonzales, Sonia, Jibrell, Hodan, Klaphake, Jonathan, Vasudeva, Shikha, Hovmand, Nichlas, Kamstrup, Thobias, Bergsøe, Christina Marisa, Østergaard, Lars, Hertz, Mathias A., Lindnér, Cecilia Ebba Clara Ellinor, Havmøller, Signe Ravn, Exposito, Maria, Grüttner-Durmaz, Manuela, Horban, Andrzej, Virachit, Sophie, Ongko, Juwinda, Parmar, Mahesh KB, Kiweewa, Francis, Osinusi, Anu, Willis, Angela, Yan, Li, Bielica, Mona, Frye, Leanna, Galcik, Michael, Proffitt, Calvin, Smith, Kenneth, Murphy, Joseph, Flosi, Adam, Wenner, Christine

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Specifications of the ACMG/AMP Variant Classification Guidelines for Germline DICER1 Variant Curation von Hatton, Jessica N., Frone, Megan N., Cox, Hannah C., Crowley, Stephanie B., Hiraki, Susan, Yokoyama, Noriko N., Abul-Husn, Noura S., Amatruda, James F., Anderson, Michael J., Bofill-De Ros, Xavier, Carr, Ann G., Chao, Elizabeth C., Chen, Kenneth S., Gu, Shuo, Higgs, Cecilia, Machado, Jerry, Ritter, Deborah, Schultz, Kris Ann P., Soper, Emily R., Wu, Mona K., Mester, Jessica L., Kim, Jung, Foulkes, William D., Witkowski, Leora, Stewart, Douglas R.

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Bi-allelic Variants in TONSL Cause SPONASTRIME Dysplasia and a Spectrum of Skeletal Dysplasia Phenotypes von Phillips, Jennifer B., Lanza, Denise G., Jain, Mahim, Raman, Vandana, Chitayat, David, Chinn, Ivan K., Bertuch, Alison A., Bamshad, Michael, Savarirayan, Ravi, Doddapaneni, Harsha, Muzny, Donna, Gibbs, Richard A., Rosenfeld, Jill A., Postlethwait, John, Beaudet, Arthur L., Ranza, Emmanuelle, Cormier-Daire, Valérie, Orange, Jordan S., Allard, Patrick, Barseghyan, Hayk, Batzli, Gabriel F., Beggs, Alan H., Bellen, Hugo J., Bernstein, Jonathan A., Bick, David P., Briere, Lauren C., Brokamp, Elly, Brush, Matthew, Coakley, Terra R., Cope, Heidi, Davidson, Jean M., Dayal, Jyoti G., Dhar, Shweta U., Dipple, Katrina M., Dorrani, Naghmeh, Duncan, Laura, Emrick, Lisa T., Eng, Christine M., Enns, Gregory M., Fisher, Paul G., Friedman, Noah D., Gahl, William A., Glanton, Emily, Goldman, Alica M., Gourdine, Jean-Philippe F., Groden, Catherine A., Haendel, Melissa, Hamid, Rizwan, High, Frances, Huang, Yong, Karaviti, Lefkothea, Kohler, Jennefer N., Krasnewich, Donna M., Korrick, Susan, Krier, Joel B., Kyle, Jennifer E., Lau, C. Christopher, Lee, Hane, Loo, Sandra K., Loscalzo, Joseph, Martin, Martin G., Martínez-Agosto, Julian A., Marwaha, Shruti, McCormack, Colleen E., McCray, Alexa T., Metz, Thomas O., Murdock, David R., Newberry, J. Scott, Nicholas, Sarah K., Palmer, Christina G.S., Papp, Jeanette C., Phillips, John A., Posey, Jennifer E., Pusey, Barbara N., Sampson, Jacinda B., Shakachite, Lisa, Signer, Rebecca, Silverman, Edwin K., Spillmann, Rebecca C., Stoler, Joan M., Stong, Nicholas, Sweetser, David A., Tan, Queenie K.-G., Tran, Alyssa A., Vogel, Tiphanie P., Wahl, Colleen E., Wangler, Michael F., Waters, Katrina M., Westerfield, Monte, Wise, Anastasia L., Yang, John, Yang, Yaping, Yoon, Amanda J., Zastrow, Diane B., Zhao, Chunli, Offiah, Amaka C., Carey, John C., Bacino, Carlos A., Campeau, Philippe M., Lee, Brendan

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Large-scale evaluation of outcomes after a genetic diagnosis in children with severe developmental disorders von Copeland, Harriet, Low, Karen J., Wynn, Sarah L., Ahmed, Ayesha, Arthur, Victoria, Balasubramanian, Meena, Bennett, Katya, Berg, Jonathan, Bertoli, Marta, Bryson, Lisa, Bucknall, Catrin, Campbell, Jamie, Chandler, Kate, Chauhan, Jaynee, Clarkson, Amy, Coles, Rachel, Conti, Hector, Costello, Philandra, Coupar, Tessa, Craig, Amy, Dean, John, Dillon, Amy, Dixit, Abhijit, Drew, Kathryn, Eason, Jacqueline, Forzano, Francesca, Foulds, Nicola, Gardham, Alice, Ghali, Neeti, Green, Andrew, Hanna, William, Harrison, Rachel, Hegarty, Mairead, Higgs, Jenny, Holder, Muriel, Irving, Rachel, Jain, Vani, Johnson, Katie, Jolley, Rachel, Jones, Wendy D., Jones, Gabriela, Joss, Shelagh, Kalinauskiene, Ruta, Kanani, Farah, Kavanagh, Karl, Khan, Mahmudur, Khan, Naz, Kivuva, Emma, Lahiri, Nayana, Lakhani, Neeta, Lampe, Anne, Lynch, Sally Ann, Mansour, Sahar, Marsden, Alice, Massey, Hannah, McKee, Shane, Mohammed, Shehla, Naik, Swati, Nesarajah, Mithushanaa, Newbury-Ecob, Ruth, Osborne, Fiona, Parker, Michael J., Patterson, Jenny, Pottinger, Caroline, Prapa, Matina, Prescott, Katrina, Quinn, Shauna, Radley, Jessica A., Robart, Sarah, Ross, Alison, Rosti, Giulia, Sansbury, Francis H., Sarkar, Ajoy, Searle, Claire, Shannon, Nora, Shears, Debbie, Smithson, Sarah, Stewart, Helen, Suri, Mohnish, Tadros, Shereen, Theobald, Rachel, Thomas, Rhian, Tsoulaki, Olga, Vasudevan, Pradeep, Rodriguez, Maribel Verdesoto, Vittery, Emma, Whyte, Sinead, Woods, Emily, Wright, Thomas, Zocche, David, Firth, Helen V., Wright, Caroline F.

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Efficacy and safety of two neutralising monoclonal antibody therapies, sotrovimab and BRII-196 plus BRII-198, for adults hospitalised with COVID-19 (TICO): a randomised controlled... von Self, Wesley H, Sandkovsky, Uriel, Reilly, Cavan S, Vock, David M, Gottlieb, Robert L, Mack, Michael, Golden, Kevin, Dishner, Emma, Vekstein, Andrew, Ko, Emily R, Der, Tatyana, Franzone, John, Almasri, Eyad, Fayed, Mohamed, Filbin, Michael R, Hibbert, Kathryn A, Rice, Todd W, Casey, Jonathan D, Hayanga, J Awori, Badhwar, Vinay, Leshnower, Bradley G, Sharifpour, Milad, Knowlton, Kirk U, Peltan, Ithan D, Bakowska, Elizieta, Kowalska, Justyna, Bowdish, Michael E, Sturek, Jeffrey M, Rogers, Angela J, Files, D Clark, Mosier, Jarrod M, Gong, Michelle N, Douin, David J, Hite, R Duncan, Trautner, Barbara W, Jain, Mamta K, Gardner, Edward M, Khan, Akram, Jensen, Jens-Ulrik, Matthay, Michael A, Ginde, Adit A, Brown, Samuel M, Higgs, Elizabeth S, Pett, Sarah, Weintrob, Amy C, Chang, Christina C, Murrary, Daniel D, Gunthard, Huldrych F, Moquete, Ellen, Grandits, Greg, Engen, Nicole, Grund, Birgit, Sharma, Shweta, Cao, Huyen, Gupta, Rajesh, Osei, Suzette, Margolis, David, Zhu, Qing, Polizzotto, Mark N, Babiker, Abdel G, Davey, Victoria J, Kan, Virginia, Thompson, B Taylor, Gelijns, Annetine C, Neaton, James D, Lane, H Clifford, Lundgren, Jens D

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