TGF-β1 → SMAD/p53/USF2 → PAI-1 transcriptional axis in ureteral obstruction-induced renal fibrosis von Samarakoon, Rohan, Overstreet, Jessica M, Higgins, Stephen P, Higgins, Paul J

Volltext

The TGF-β1/p53/PAI-1 Signaling Axis in Vascular Senescence: Role of Caveolin-1 von Samarakoon, Rohan, Higgins, Stephen P, Higgins, Craig E, Higgins, Paul J

Volltext

Redox-induced Src kinase and caveolin-1 signaling in TGF-β1-initiated SMAD2/3 activation and PAI-1 expression von Samarakoon, Rohan, Chitnis, Subhanir S, Higgins, Stephen P, Higgins, Craig E, Krepinsky, Joan C, Higgins, Paul J

Volltext

SERPINE1: Role in Cholangiocarcinoma Progression and a Therapeutic Target in the Desmoplastic Microenvironment von Czekay, Ralf-Peter, Higgins, Craig E, Aydin, Hasan Basri, Samarakoon, Rohan, Subasi, Nusret Bekir, Higgins, Stephen P, Lee, Hwajeong, Higgins, Paul J

Volltext

PAI-1: An Integrator of Cell Signaling and Migration von Czekay, Ralf-Peter, Wilkins-Port, Cynthia E., Higgins, Stephen P., Freytag, Jennifer, Overstreet, Jessica M., Klein, R. Matthew, Higgins, Craig E., Samarakoon, Rohan, Higgins, Paul J.

Volltext

TGF-β1/p53 signaling in renal fibrogenesis von Higgins, Stephen P., Tang, Yi, Higgins, Craig E., Mian, Badar, Zhang, Wenzheng, Czekay, Ralf-Peter, Samarakoon, Rohan, Conti, David J., Higgins, Paul J.

Volltext

PAI-1 Mediates the TGF-β1+EGF-Induced “Scatter” Response in Transformed Human Keratinocytes von Freytag, Jennifer, Wilkins-Port, Cynthia E., Higgins, Craig E., Higgins, Stephen P., Samarakoon, Rohan, Higgins, Paul J.

Volltext

Differential requirement for MEK/ERK and SMAD signaling in PAI-1 and CTGF expression in response to microtubule disruption von Samarakoon, Rohan, Higgins, Craig E., Higgins, Stephen P., Higgins, Paul J.

Volltext

Yaws von Marks, Michael, Lebari, Dornubari, Solomon, Anthony W, Higgins, Stephen P

Volltext

The Genomic Response to TGF-β1 Dictates Failed Repair and Progression of Fibrotic Disease in the Obstructed Kidney von Higgins, Craig E, Tang, Jiaqi, Higgins, Stephen P, Gifford, Cody C, Mian, Badar M, Jones, David M, Zhang, Wenzheng, Costello, Angelica, Conti, David J, Samarakoon, Rohan, Higgins, Paul J

Volltext

TGF‐β1–p53 cooperativity regulates a profibrotic genomic program in the kidney: molecular mechanisms and clinical implications von Higgins, Craig E., Tang, Jiaqi, Mian, Badar M., Higgins, Stephen P., Gifford, Cody C., Conti, David J., Meldrum, Kirstan K., Samarakoon, Rohan, Higgins, Paul J.

Volltext

The dark art of syphilis serology - an analysis of testing algorithms at a UK reference laboratory von Scobie, Antonia, Brown, Colin S, French, Patrick, Donati, Matthew, Muir, Peter, Templeton, Kate, Higgins, Stephen P, Patel, Hemanti, Alexander, Sarah, Fifer, Helen

Volltext

Rash and hepatitis within days of starting a new antiretroviral regimen: nevirapine hypersensitivity, secondary syphilis or both? von Saxon, Cara J, Helbert, Matthew R, Komolafe, Adeniyi J, Higgins, Stephen P

Volltext

Complex Regulation of the Pericellular Proteolytic Microenvironment during Tumor Progression and Wound Repair: Functional Interactions between the Serine Protease and Matrix Metall... von Wilkins-Port, Cynthia E., Higgins, Stephen P., Higgins, Craig E., Kobori-Hotchkiss, Issey, Higgins, Paul J.

Volltext

A small molecule PAI-1 functional inhibitor attenuates neointimal hyperplasia and vascular smooth muscle cell survival by promoting PAI-1 cleavage von Simone, Tessa M., Higgins, Stephen P., Archambeault, Jaclyn, Higgins, Craig E., Ginnan, Roman G., Singer, Harold, Higgins, Paul J.

Volltext

SERPINE1: A Molecular Switch in the Proliferation-Migration Dichotomy in Wound-"Activated" Keratinocytes von Simone, Tessa M, Higgins, Craig E, Czekay, Ralf-Peter, Law, Brian K, Higgins, Stephen P, Archambeault, Jaclyn, Kutz, Stacie M, Higgins, Paul J

Volltext

The Basic Helix-Loop-Helix/Leucine Zipper Transcription Factor USF2 Integrates Serum-Induced PAI-1 Expression and Keratinocyte Growth von Qi, Li, Higgins, Craig E., Higgins, Stephen P., Law, Brian K., Simone, Tessa M., Higgins, Paul J.

Volltext

PAI-1 Regulates the Invasive Phenotype in Human Cutaneous Squamous Cell Carcinoma von Freytag, Jennifer, Wilkins-Port, Cynthia E., Higgins, Craig E., Carlson, J. Andrew, Noel, Agnes, Foidart, Jean-Michel, Higgins, Stephen P., Samarakoon, Rohan, Higgins, Paul J.

Volltext

PAI-1 Expression Is Required for HDACi-Induced Proliferative Arrest in ras -Transformed Renal Epithelial Cells von Higgins, Stephen P., Higgins, Craig E., Higgins, Paul J.

Volltext

SERPINE1 (PAI-1) is deposited into keratinocyte migration “trails” and required for optimal monolayer wound repair von Providence, Kirwin M., Higgins, Stephen P., Mullen, Andrew, Battista, Ashley, Samarakoon, Rohan, Higgins, Craig E., Wilkins-Port, Cynthia E., Higgins, Paul J.

Volltext