The TGF-β1/p53/PAI-1 Signaling Axis in Vascular Senescence: Role of Caveolin-1 von Samarakoon, Rohan, Higgins, Stephen P, Higgins, Craig E, Higgins, Paul J

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Redox-induced Src kinase and caveolin-1 signaling in TGF-β1-initiated SMAD2/3 activation and PAI-1 expression von Samarakoon, Rohan, Chitnis, Subhanir S, Higgins, Stephen P, Higgins, Craig E, Krepinsky, Joan C, Higgins, Paul J

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SERPINE1: Role in Cholangiocarcinoma Progression and a Therapeutic Target in the Desmoplastic Microenvironment von Czekay, Ralf-Peter, Higgins, Craig E, Aydin, Hasan Basri, Samarakoon, Rohan, Subasi, Nusret Bekir, Higgins, Stephen P, Lee, Hwajeong, Higgins, Paul J

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PAI-1: An Integrator of Cell Signaling and Migration von Czekay, Ralf-Peter, Wilkins-Port, Cynthia E., Higgins, Stephen P., Freytag, Jennifer, Overstreet, Jessica M., Klein, R. Matthew, Higgins, Craig E., Samarakoon, Rohan, Higgins, Paul J.

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TGF-β1/p53 signaling in renal fibrogenesis von Higgins, Stephen P., Tang, Yi, Higgins, Craig E., Mian, Badar, Zhang, Wenzheng, Czekay, Ralf-Peter, Samarakoon, Rohan, Conti, David J., Higgins, Paul J.

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PAI-1 Mediates the TGF-β1+EGF-Induced “Scatter” Response in Transformed Human Keratinocytes von Freytag, Jennifer, Wilkins-Port, Cynthia E., Higgins, Craig E., Higgins, Stephen P., Samarakoon, Rohan, Higgins, Paul J.

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SERPINE1 expression discriminates site-specific metastasis in human melanoma von Klein, R. Matthew, Bernstein, Daniel, Higgins, Steven P., Higgins, Craig E., Higgins, Paul J.

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Differential requirement for MEK/ERK and SMAD signaling in PAI-1 and CTGF expression in response to microtubule disruption von Samarakoon, Rohan, Higgins, Craig E., Higgins, Stephen P., Higgins, Paul J.

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The Genomic Response to TGF-β1 Dictates Failed Repair and Progression of Fibrotic Disease in the Obstructed Kidney von Higgins, Craig E, Tang, Jiaqi, Higgins, Stephen P, Gifford, Cody C, Mian, Badar M, Jones, David M, Zhang, Wenzheng, Costello, Angelica, Conti, David J, Samarakoon, Rohan, Higgins, Paul J

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TGF‐β1–p53 cooperativity regulates a profibrotic genomic program in the kidney: molecular mechanisms and clinical implications von Higgins, Craig E., Tang, Jiaqi, Mian, Badar M., Higgins, Stephen P., Gifford, Cody C., Conti, David J., Meldrum, Kirstan K., Samarakoon, Rohan, Higgins, Paul J.

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Complex Regulation of the Pericellular Proteolytic Microenvironment during Tumor Progression and Wound Repair: Functional Interactions between the Serine Protease and Matrix Metall... von Wilkins-Port, Cynthia E., Higgins, Stephen P., Higgins, Craig E., Kobori-Hotchkiss, Issey, Higgins, Paul J.

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A small molecule PAI-1 functional inhibitor attenuates neointimal hyperplasia and vascular smooth muscle cell survival by promoting PAI-1 cleavage von Simone, Tessa M., Higgins, Stephen P., Archambeault, Jaclyn, Higgins, Craig E., Ginnan, Roman G., Singer, Harold, Higgins, Paul J.

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SERPINE1: A Molecular Switch in the Proliferation-Migration Dichotomy in Wound-"Activated" Keratinocytes von Simone, Tessa M, Higgins, Craig E, Czekay, Ralf-Peter, Law, Brian K, Higgins, Stephen P, Archambeault, Jaclyn, Kutz, Stacie M, Higgins, Paul J

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PAI-1 Regulates the Invasive Phenotype in Human Cutaneous Squamous Cell Carcinoma von Freytag, Jennifer, Wilkins-Port, Cynthia E., Higgins, Craig E., Carlson, J. Andrew, Noel, Agnes, Foidart, Jean-Michel, Higgins, Stephen P., Samarakoon, Rohan, Higgins, Paul J.

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The Basic Helix-Loop-Helix/Leucine Zipper Transcription Factor USF2 Integrates Serum-Induced PAI-1 Expression and Keratinocyte Growth von Qi, Li, Higgins, Craig E., Higgins, Stephen P., Law, Brian K., Simone, Tessa M., Higgins, Paul J.

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PAI-1 Expression Is Required for HDACi-Induced Proliferative Arrest in ras -Transformed Renal Epithelial Cells von Higgins, Stephen P., Higgins, Craig E., Higgins, Paul J.

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SERPINE1 (PAI-1) is deposited into keratinocyte migration “trails” and required for optimal monolayer wound repair von Providence, Kirwin M., Higgins, Stephen P., Mullen, Andrew, Battista, Ashley, Samarakoon, Rohan, Higgins, Craig E., Wilkins-Port, Cynthia E., Higgins, Paul J.

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PAI-1 transcriptional regulation during the G0 → G1 transition in human epidermal keratinocytes von Qi, Li, Allen, Rosalie R., Lu, Qi, Higgins, Craig E., Garone, Rosemarie, Staiano-Coico, Lisa, Higgins, Paul J.

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SERPINE1 (PAI-1) Is a Prominent Member of the Early G0 → G1 Transition “Wound Repair” Transcriptome in p53 Mutant Human Keratinocytes von Qi, Li, Higgins, Stephen P., Lu, Qi, Samarakoon, Rohan, Wilkins-Port, Cynthia E., Ye, Qunhui, Higgins, Craig E., Staiano-Coico, Lisa, Higgins, Paul J.

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TGF-β1 -Induced Expression of the Anti-Apoptotic PAI-1 Protein Requires EGFR Signaling von Higgins, Stephen P, Samarakoon, Rohan, Higgins, Craig E, Freytag, Jennifer, Wilkins-Port, Cynthia E, Higgins, Paul J

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