Nitric oxide orchestrates metabolic rewiring in M1 macrophages by targeting aconitase 2 and pyruvate dehydrogenase von Palmieri, Erika M., Gonzalez-Cotto, Marieli, Baseler, Walter A., Davies, Luke C., Ghesquière, Bart, Maio, Nunziata, Rice, Christopher M., Rouault, Tracey A., Cassel, Teresa, Higashi, Richard M., Lane, Andrew N., Fan, Teresa W.-M., Wink, David A., McVicar, Daniel W.

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The Metabolic Profile of Tumors Depends on Both the Responsible Genetic Lesion and Tissue Type von Yuneva, Mariia O., Fan, Teresa W.M., Allen, Thaddeus D., Higashi, Richard M., Ferraris, Dana V., Tsukamoto, Takashi, Matés, José M., Alonso, Francisco J., Wang, Chunmei, Seo, Youngho, Chen, Xin, Bishop, J. Michael

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Targeting Lactate Dehydrogenase-A Inhibits Tumorigenesis and Tumor Progression in Mouse Models of Lung Cancer and Impacts Tumor-Initiating Cells von Xie, Han, Hanai, Jun-ichi, Ren, Jian-Guo, Kats, Lev, Burgess, Kerri, Bhargava, Parul, Signoretti, Sabina, Billiard, Julia, Duffy, Kevin J., Grant, Aaron, Wang, Xiaoen, Lorkiewicz, Pawel K., Schatzman, Sabrina, Bousamra, Michael, Lane, Andrew N., Higashi, Richard M., Fan, Teresa W.M., Pandolfi, Pier Paolo, Sukhatme, Vikas P., Seth, Pankaj

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Exploring cancer metabolism using stable isotope-resolved metabolomics (SIRM) von Bruntz, Ronald C., Lane, Andrew N., Higashi, Richard M., Fan, Teresa W.-M.

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Glucose-Independent Glutamine Metabolism via TCA Cycling for Proliferation and Survival in B Cells von Le, Anne, Lane, Andrew N., Hamaker, Max, Bose, Sminu, Gouw, Arvin, Barbi, Joseph, Tsukamoto, Takashi, Rojas, Camilio J., Slusher, Barbara S., Zhang, Haixia, Zimmerman, Lisa J., Liebler, Daniel C., Slebos, Robbert J.C., Lorkiewicz, Pawel K., Higashi, Richard M., Fan, Teresa W.M., Dang, Chi V.

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Altered regulation of metabolic pathways in human lung cancer discerned by 13C stable isotope-resolved metabolomics (SIRM) von Fan, Teresa WM, Lane, Andrew N, Higashi, Richard M, Farag, Mohamed A, Gao, Hong, Bousamra, Michael, Miller, Donald M

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De novo synthesis of serine and glycine fuels purine nucleotide biosynthesis in human lung cancer tissues von Fan, Teresa W.M., Bruntz, Ronald C., Yang, Ye, Song, Huan, Chernyavskaya, Yelena, Deng, Pan, Zhang, Yan, Shah, Parag P., Beverly, Levi J., Qi, Zhen, Mahan, Angela L., Higashi, Richard M., Dang, Chi V., Lane, Andrew N.

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Acute loss of iron–sulfur clusters results in metabolic reprogramming and generation of lipid droplets in mammalian cells von Crooks, Daniel R., Maio, Nunziata, Lane, Andrew N., Jarnik, Michal, Higashi, Richard M., Haller, Ronald G., Yang, Ye, Fan, Teresa W-M., Linehan, W. Marston, Rouault, Tracey A.

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Noninvasive liquid diet delivery of stable isotopes into mouse models for deep metabolic network tracing von Sun, Ramon C., Fan, Teresa W.-M., Deng, Pan, Higashi, Richard M., Lane, Andrew N., Le, Anh-Thu, Scott, Timothy L., Sun, Qiushi, Warmoes, Marc O., Yang, Ye

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Metabolic reprogramming in tumors: Contributions of the tumor microenvironment von Lane, Andrew N., Higashi, Richard M., Fan, Teresa W-M.

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Blockade of 6-phosphogluconate dehydrogenase generates CD8+ effector T cells with enhanced anti-tumor function von Daneshmandi, Saeed, Cassel, Teresa, Lin, Penghui, Higashi, Richard M., Wulf, Gerburg M., Boussiotis, Vassiliki A., Fan, Teresa W.-M., Seth, Pankaj

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6-Phosphogluconate dehydrogenase (6PGD), a key checkpoint in reprogramming of regulatory T cells metabolism and function von Daneshmandi, Saeed, Cassel, Teresa, Higashi, Richard M, Fan, Teresa W-M, Seth, Pankaj

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Myeloid-derived suppressor cell mitochondrial fitness governs chemotherapeutic efficacy in hematologic malignancies von Daneshmandi, Saeed, Choi, Jee Eun, Yan, Qi, MacDonald, Cameron R., Pandey, Manu, Goruganthu, Mounika, Roberts, Nathan, Singh, Prashant K., Higashi, Richard M., Lane, Andrew N., Fan, Teresa W-M., Wang, Jianmin, McCarthy, Philip L., Repasky, Elizabeth A., Mohammadpour, Hemn

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Knockdown of Malic Enzyme 2 Suppresses Lung Tumor Growth, Induces Differentiation and Impacts PI3K/AKT Signaling von Ren, Jian-Guo, Seth, Pankaj, Clish, Clary B., Lorkiewicz, Pawel K., Higashi, Richard M., Lane, Andrew N., Fan, Teresa W.-M., Sukhatme, Vikas P.

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Innate immune activation by checkpoint inhibition in human patient-derived lung cancer tissues von Fan, Teresa Wm, Higashi, Richard M, Song, Huan, Daneshmandi, Saeed, Mahan, Angela L, Purdom, Matthew S, Bocklage, Therese J, Pittman, Thomas A, He, Daheng, Wang, Chi, Lane, Andrew N

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Challenges of Spatially Resolved Metabolism in Cancer Research von Lane, Andrew N, Higashi, Richard M, Fan, Teresa W-M

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Preclinical models for interrogating drug action in human cancers using Stable Isotope Resolved Metabolomics (SIRM) von Lane, Andrew N., Higashi, Richard M., Fan, Teresa W.-M.

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A novel deconvolution method for modeling UDP-N-acetyl-D-glucosamine biosynthetic pathways based on 13C mass isotopologue profiles under non-steady-state conditions von Moseley, Hunter NB, Lane, Andrew N, Belshoff, Alex C, Higashi, Richard M, Fan, Teresa WM

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Resolving Metabolic Heterogeneity in Experimental Models of the Tumor Microenvironment from a Stable Isotope Resolved Metabolomics Perspective von Fan, Teresa W-M, Higashi, Richard M, Chernayavskaya, Yelena, Lane, Andrew N

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NMR Methods for Determining Lipid Turnover via Stable Isotope Resolved Metabolomics von Lin, Penghui, Dai, Li, Crooks, Daniel R, Neckers, Leonard M, Higashi, Richard M, Fan, Teresa W-M, Lane, Andrew N

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