OPC-67683, a nitro-dihydro-imidazooxazole derivative with promising action against tuberculosis in vitro and in mice von Matsumoto, Makoto, Hashizume, Hiroyuki, Tomishige, Tatsuo, Kawasaki, Masanori, Tsubouchi, Hidetsugu, Sasaki, Hirofumi, Shimokawa, Yoshihiko, Komatsu, Makoto

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Phase 2, randomized, double‐blind, placebo‐controlled, 4‐week study to evaluate the safety and efficacy of OPA‐ 15406 (difamilast), a new topical selective phosphodiesterase type‐4... von Saeki, Hidehisa, Baba, Naoko, Oshiden, Kazuhide, Abe, Yuji, Tsubouchi, Hidetsugu

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An Interim Report of a Phase 3, Long-Term, Open-Label Study to Evaluate Efficacy and Safety of Difamilast Ointment in Japanese Infants with Atopic Dermatitis von Saeki, Hidehisa, Ohya, Yukihiro, Baba, Naoko, Imamura, Tomomi, Yokota, Daisuke, Tsubouchi, Hidetsugu

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Predictive factors of the pharmacological action of tolvaptan in patients with liver cirrhosis: a post hoc analysis von Sakaida, Isao, Terai, Shuji, Nakajima, Koji, Shibasaki, Yoshiyuki, Tachikawa, Sayaka, Tsubouchi, Hidetsugu

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Synthesis and Antituberculosis Activity of a Novel Series of Optically Active 6-Nitro-2,3-dihydroimidazo[2,1-b]oxazoles von Sasaki, Hirofumi, Haraguchi, Yoshikazu, Itotani, Motohiro, Kuroda, Hideaki, Hashizume, Hiroyuki, Tomishige, Tatsuo, Kawasaki, Masanori, Matsumoto, Makoto, Komatsu, Makoto, Tsubouchi, Hidetsugu

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Efficacy and safety of topical OPA‐15406, a new phosphodiesterase 4 inhibitor, in Japanese patients with atopic dermatitis for 8 weeks: A phase 2, randomized, double‐blind, placebo... von Saeki, Hidehisa, Kawashima, Makoto, Sugaya, Satoko, Oshiden, Kazuhide, Tsubouchi, Hidetsugu, Onozuka, Takashi, Takahashi, Yoshimasa, Takata, Hideyasu, Yoshihara, Nobuko, Toyofuku, Kazutomo, Kitahara, Hiroto, Izumi, Tatsuya, Nogita, Toshitatsu, Yamamoto, Aisaku, Nakasu, Ichiro, Kume, Akihiro, Sasase, Akihiro, Watanabe, Masako, Houki, Ken

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Can serum albumin level affect the pharmacological action of tolvaptan in patients with liver cirrhosis? A post hoc analysis of previous clinical trials in Japan von Sakaida, Isao, Nakajima, Koji, Okita, Kiwamu, Hori, Masatsugu, Izumi, Tohru, Sakurai, Masaya, Shibasaki, Yoshiyuki, Tachikawa, Sayaka, Tsubouchi, Hidetsugu, Oka, Hiromi, Kobayashi, Hiroyuki

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Difamilast ointment in adult patients with atopic dermatitis: A phase 3 randomized, double-blind, vehicle-controlled trial von Saeki, Hidehisa, Ito, Kensuke, Yokota, Daisuke, Tsubouchi, Hidetsugu

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Long-term safety profile of tolvaptan in autosomal dominant polycystic kidney disease patients: TEMPO Extension Japan Trial von Muto, Satoru, Okada, Tadashi, Yasuda, Moriyoshi, Tsubouchi, Hidetsugu, Nakajima, Koji, Horie, Shigeo

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Difamilast Ointment in Japanese Adult and Pediatric Patients with Atopic Dermatitis: A Phase III, Long-Term, Open-Label Study von Saeki, Hidehisa, Imamura, Tomomi, Yokota, Daisuke, Tsubouchi, Hidetsugu

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Long-term safety profile of tolvaptan in autosomal dominant polycystic kidney disease patients: TEMPO Extension Japan Trial [Corrigendum] von Muto, Satoru, Okada, Tadashi, Yasuda, Moriyoshi, Tsubouchi, Hidetsugu, Nakajima, Koji, Horie, Shigeo

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Synthesis and Antibacterial Activities of Optically Active Substituted 1, 2-Dihydro-6-oxo-6H-pyrrolo[3, 2, 1-ij]quinoline-5-carboxylic Acids von TSUJI, Koichi, TSUBOUCHI, Hidetsugu, ISHIKAWA, Hiroshi

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Synthesis and Antibacterial Activities of 2-Oxaisocephems von TSUBOUCHI, Hidetsugu, TSUJI, Koichi, YASUMURA, Koichi, ISHIKAWA, Hiroshi

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Difamilast ointment in adult patients with atopic dermatitis: A phase 3 randomized double-blind vehicle-controlled trial von Saeki, Hidehisa

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Synthesis and structure-activity relationships of novel antiseptics von Tsubouchi, Hidetsugu, Ohguro, Kinue, Yasumura, Koichi, Ishikawa, Hiroshi, Kikuchi, Mikio

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Synthesis and structure-activity relationships of cephalosporins, 2-isocephems, and 2-oxaisocephems with C-3′ or C-7 catechol or related aromatics von Tsuji, Koichi, Tsubouchi, Hidetsugu, Yasumura, Koichi, Matsumoto, Makoto, Ishikawa, Hiroshi

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Synthesis and biological properties of a series of optically active 2-oxaisocephems von Tsubouchi, Hidetsugu, Ishikawa, Hiroshi

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Use of 4- Nitro-N-phthalimide as Protective Group of Primary Amines von Tsubouchi, Hidetsugu, Tsuji, Koichi, Ishikawa, Hiroshi

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Synthesis and Some Properties of 2-Azathiabenzene 1-Oxides von IKEDA, MASAZUMI, TSUBOUCHI, HIDETSUGU, TSUNEKAWA, MASAYOSHI, KONDO, HIROSHI, TAMURA, YASUMITSU

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Synthesis and biological activity of new optically active 2-oxaisocephems: 3-( N-alkylpyridinium-4′-thio)methyl derivatives von Ishikawa, Hiroshi, Tsubouchi, Hidetsugu, Yasumura, Koichi

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