PLGA-particle vaccine carrying TLR3/RIG-I ligand Riboxxim synergizes with immune checkpoint blockade for effective anti-cancer immunotherapy von Koerner, Julia, Horvath, Dennis, Herrmann, Valerie L., MacKerracher, Anna, Gander, Bruno, Yagita, Hideo, Rohayem, Jacques, Groettrup, Marcus

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PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors von Curran, Michael A, Montalvo, Welby, Yagita, Hideo, Allison, James P

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Interleukin-11-expressing fibroblasts have a unique gene signature correlated with poor prognosis of colorectal cancer von Nishina, Takashi, Deguchi, Yutaka, Ohshima, Daisuke, Takeda, Wakami, Ohtsuka, Masato, Shichino, Shigeyuki, Ueha, Satoshi, Yamazaki, Soh, Kawauchi, Mika, Nakamura, Eri, Nishiyama, Chiharu, Kojima, Yuko, Adachi-Akahane, Satomi, Hasegawa, Mizuho, Nakayama, Mizuho, Oshima, Masanobu, Yagita, Hideo, Shibuya, Kazutoshi, Mikami, Tetuo, Inohara, Naohiro, Matsushima, Kouji, Tada, Norihiro, Nakano, Hiroyasu

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Cancer-Cell-Intrinsic cGAS Expression Mediates Tumor Immunogenicity von Schadt, Linda, Sparano, Colin, Schweiger, Nicole Angelika, Silina, Karina, Cecconi, Virginia, Lucchiari, Giulia, Yagita, Hideo, Guggisberg, Emilien, Saba, Sascha, Nascakova, Zuzana, Barchet, Winfried, van den Broek, Maries

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Co-administration of RANKL and CTLA4 Antibodies Enhances Lymphocyte-Mediated Antitumor Immunity in Mice von Ahern, Elizabeth, Harjunpää, Heidi, Barkauskas, Deborah, Allen, Stacey, Takeda, Kazuyoshi, Yagita, Hideo, Wyld, David, Dougall, William C, Teng, Michele W L, Smyth, Mark J

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The allergy mediator histamine confers resistance to immunotherapy in cancer patients via activation of the macrophage histamine receptor H1 von Li, Hongzhong, Xiao, Yi, Li, Qin, Yao, Jun, Yuan, Xiangliang, Zhang, Yuan, Yin, Xuedong, Saito, Yohei, Fan, Huihui, Li, Ping, Kuo, Wen-Ling, Halpin, Angela, Gibbons, Don L., Yagita, Hideo, Zhao, Zhongming, Pang, Da, Ren, Guosheng, Yee, Cassian, Lee, J. Jack, Yu, Dihua

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Tumor-associated macrophages regulate tumorigenicity and anticancer drug responses of cancer stem/initiating cells von Jinushi, Masahisa, Chiba, Shigeki, Yoshiyama, Hironori, Masutomi, Kenkichi, Kinoshita, Ichiro, Dosaka-Akita, Hirotoshi, Yagita, Hideo, Takaoka, Akinori, Tahara, Hideaki

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CD39+PD-1+CD8+ T cells mediate metastatic dormancy in breast cancer von Tallón de Lara, Paulino, Castañón, Héctor, Vermeer, Marijne, Núñez, Nicolás, Silina, Karina, Sobottka, Bettina, Urdinez, Joaquín, Cecconi, Virginia, Yagita, Hideo, Movahedian Attar, Farkhondeh, Hiltbrunner, Stefanie, Glarner, Isabelle, Moch, Holger, Tugues, Sònia, Becher, Burkhard, van den Broek, Maries

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Tumor-infiltrating DCs suppress nucleic acid–mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1 von Chiba, Shigeki, Baghdadi, Muhammad, Akiba, Hisaya, Yoshiyama, Hironori, Kinoshita, Ichiro, Dosaka-Akita, Hirotoshi, Fujioka, Yoichiro, Ohba, Yusuke, Gorman, Jacob V, Colgan, John D, Hirashima, Mitsuomi, Uede, Toshimitsu, Takaoka, Akinori, Yagita, Hideo, Jinushi, Masahisa

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An anti-RANKL treatment reduces muscle inflammation and dysfunction and strengthens bone in dystrophic mice von Hamoudi, Dounia, Marcadet, Laetitia, Piette Boulanger, Antoine, Yagita, Hideo, Bouredji, Zineb, Argaw, Anteneh, Frenette, Jérôme

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Differential contribution of three immune checkpoint (VISTA, CTLA-4, PD-1) pathways to antitumor responses against squamous cell carcinoma von Kondo, Yuta, Ohno, Tatsukuni, Nishii, Naoto, Harada, Kiyoshi, Yagita, Hideo, Azuma, Miyuki

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Lymph Node Mesenchymal and Endothelial Stromal Cells Cooperate via the RANK-RANKL Cytokine Axis to Shape the Sinusoidal Macrophage Niche von Camara, Abdouramane, Cordeiro, Olga G., Alloush, Farouk, Sponsel, Janina, Chypre, Mélanie, Onder, Lucas, Asano, Kenichi, Tanaka, Masato, Yagita, Hideo, Ludewig, Burkhard, Flacher, Vincent, Mueller, Christopher G.

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Anti-ErbB-2 mAb therapy requires type I and II interferons and synergizes with anti-PD-1 or anti-CD137 mAb therapy von Stagg, John, Loi, Sherene, Divisekera, Upulie, Ngiow, Shin Foong, Duret, Helene, Yagita, Hideo, Teng, Michele W, Smyth, Mark J

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TGFβ-dependent expression of PD-1 and PD-L1 controls CD8(+) T cell anergy in transplant tolerance von Baas, Marije, Besançon, Alix, Goncalves, Tania, Valette, Fabrice, Yagita, Hideo, Sawitzki, Birgit, Volk, Hans-Dieter, Waeckel-Enée, Emmanuelle, Rocha, Benedita, Chatenoud, Lucienne, You, Sylvaine

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A Single Strain of Clostridium butyricum Induces Intestinal IL-10-Producing Macrophages to Suppress Acute Experimental Colitis in Mice von Hayashi, Atsushi, Sato, Toshiro, Kamada, Nobuhiko, Mikami, Yohei, Matsuoka, Katsuyoshi, Hisamatsu, Tadakazu, Hibi, Toshifumi, Roers, Axel, Yagita, Hideo, Ohteki, Toshiaki, Yoshimura, Akihiko, Kanai, Takanori

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Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation von Nakayama, Masafumi, Akiba, Hisaya, Takeda, Kazuyoshi, Kojima, Yuko, Hashiguchi, Masaaki, Azuma, Miyuki, Yagita, Hideo, Okumura, Ko

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Safety and antibody immune response of CHP-NY-ESO-1 vaccine combined with poly-ICLC in advanced or recurrent esophageal cancer patients von Ishikawa, Takeshi, Kageyama, Shinichi, Miyahara, Yoshihiro, Okayama, Tetsuya, Kokura, Satoshi, Wang, Linan, Sato, Eiichi, Yagita, Hideo, Itoh, Yoshito, Shiku, Hiroshi

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TRAIL and its receptors as targets for cancer therapy von Yagita, Hideo, Takeda, Kazuyoshi, Hayakawa, Yoshihiro, Smyth, Mark J., Okumura, Ko

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Radiotherapy Increases the Permissiveness of Established Mammary Tumors to Rejection by Immunomodulatory Antibodies von VERBRUGGE, Inge, HAGEKYRIAKOU, Jim, HAYNES, Nicole M, SHARP, Leslie L, GALLI, Mara, WEST, Alison, MCLAUGHLIN, Nicole M, DURET, Hélène, YAGITA, Hideo, JOHNSTONE, Ricky W, SMYTH, Mark J

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A FRET biosensor for necroptosis uncovers two different modes of the release of DAMPs von Murai, Shin, Yamaguchi, Yoshifumi, Shirasaki, Yoshitaka, Yamagishi, Mai, Shindo, Ryodai, Hildebrand, Joanne M., Miura, Ryosuke, Nakabayashi, Osamu, Totsuka, Mamoru, Tomida, Taichiro, Adachi-Akahane, Satomi, Uemura, Sotaro, Silke, John, Yagita, Hideo, Miura, Masayuki, Nakano, Hiroyasu

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