3,5-Dimethylisoxazoles Act As Acetyl-lysine-mimetic Bromodomain Ligands von Hewings, David S, Wang, Minghua, Philpott, Martin, Fedorov, Oleg, Uttarkar, Sagar, Filippakopoulos, Panagis, Picaud, Sarah, Vuppusetty, Chaitanya, Marsden, Brian, Knapp, Stefan, Conway, Stuart J, Heightman, Tom D

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Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes von Hewings, David S., Heideker, Johanna, Ma, Taylur P., AhYoung, Andrew P., El Oualid, Farid, Amore, Alessia, Costakes, Gregory T., Kirchhofer, Daniel, Brasher, Bradley, Pillow, Thomas, Popovych, Nataliya, Maurer, Till, Schwerdtfeger, Carsten, Forrest, William F., Yu, Kebing, Flygare, John, Bogyo, Matthew, Wertz, Ingrid E.

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Progress in the Development and Application of Small Molecule Inhibitors of Bromodomain–Acetyl-lysine Interactions von Hewings, David S, Rooney, Timothy P. C, Jennings, Laura E, Hay, Duncan A, Schofield, Christopher J, Brennan, Paul E, Knapp, Stefan, Conway, Stuart J

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Small Molecule Inhibitors of Bromodomain–Acetyl-lysine Interactions von Brand, Michael, Measures, Angelina M, Wilson, Brian G, Cortopassi, Wilian A, Alexander, Rikki, Höss, Matthias, Hewings, David S, Rooney, Timothy P. C, Paton, Robert S, Conway, Stuart J

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Activity‐based probes for the multicatalytic proteasome von Hewings, David S., Flygare, John A., Wertz, Ingrid E., Bogyo, Matthew

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Optimization of 3,5-Dimethylisoxazole Derivatives as Potent Bromodomain Ligands von Hewings, David S, Fedorov, Oleg, Filippakopoulos, Panagis, Martin, Sarah, Picaud, Sarah, Tumber, Anthony, Wells, Christopher, Olcina, Monica M, Freeman, Katherine, Gill, Andrew, Ritchie, Alison J, Sheppard, David W, Russell, Angela J, Hammond, Ester M, Knapp, Stefan, Brennan, Paul E, Conway, Stuart J

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Short-course subcutaneous treatment with PQ Grass strongly improves symptom and medication scores in grass allergy von de Kam, P J, Zielen, S, Bernstein, J A, Berger, U, Berger, M, Cuevas, M, Cypcar, D, Fuhr-Horst, A, Greisner, W A, Jandl, M, Laßmann, S, Worm, M, Matz, J, Sher, E, Smith, C, Steven, G C, Mösges, R, Shamji, M H, DuBuske, L, Borghese, F, Oluwayi, K, Zwingers, T, Seybold, M, Armfield, O, Heath, M D, Hewings, S J, Kramer, M F, Skinner, M A

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Response to Correspondence to “Short‐course subcutaneous treatment with PQ Grass strongly improves symptom and medication scores in grass allergy” von Kam, P. J., Zielen, S., Bernstein, J. A., Berger, U., Berger, M., Cuevas, M., Cypcar, D., Fuhr‐Horst, A., Greisner, W. A., Jandl, M., Laßmann, S., Worm, M., Matz, J., Sher, E., Smith, C., Steven, G. C., Mösges, R., Shamji, M. H., DuBuske, L., Borghese, F., Oluwayi, K., Zwingers, T., Seybold, M., Armfield, O., Heath, M. D., Hewings, S. J., Kramer, M. F., Skinner, M. A.

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The adsorption of allergoids and 3-O-desacyl-4′-monophosphoryl lipid A (MPL®) to microcrystalline tyrosine (MCT) in formulations for use in allergy immunotherapy von Bell, A.J., Heath, M.D., Hewings, S.J., Skinner, M.A.

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BET bromodomain ligands: Probing the WPF shelf to improve BRD4 bromodomain affinity and metabolic stability von Jennings, Laura E., Schiedel, Matthias, Hewings, David S., Picaud, Sarah, Laurin, Corentine M.C., Bruno, Paul A., Bluck, Joseph P., Scorah, Amy R., See, Larissa, Reynolds, Jessica K., Moroglu, Mustafa, Mistry, Ishna N., Hicks, Amy, Guzanov, Pavel, Clayton, James, Evans, Charles N.G., Stazi, Giulia, Biggin, Philip C., Mapp, Anna K., Hammond, Ester M., Humphreys, Philip G., Filippakopoulos, Panagis, Conway, Stuart J.

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Activity‐based probes for the ubiquitin conjugation–deconjugation machinery: new chemistries, new tools, and new insights von Hewings, David S., Flygare, John A., Bogyo, Matthew, Wertz, Ingrid E.

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Major Allergen Content In Allergen Immunotherapy Products: The Limited Value of Numbers von Becker, S, Fassio, F, Muñoz-Cano, R, Klimek, L, Vidal, C, Heath, M D, Kündig, T M, Vogelberg, C, Toran, C, Jensen-Jarolim, E, Heffler, E, Tomazic, P V, Feindor, M, Hewings, S, Carreno, T, Morales, M, Mösges, R, Skinner, M A, Graessel, A, Hernandez, D, Kramer, M F

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Preclinical Characterization of a Next-Generation Brain Permeable, Paradox Breaker BRAF Inhibitor von Wichmann, Jürgen, Rynn, Caroline, Friess, Thomas, Petrig-Schaffland, Jeannine, Kornacker, Martin, Handl, Cornelia, Emmenegger, Jasmin, Eckmann, Jan, Herting, Frank, Frances, Nicolas, Hunziker, Daniel, Krummenacher, Daniela, Rüttinger, Dominik, Ribeiro, Alison, Bacac, Marina, Brigo, Alessandro, Hewings, David S, Dummer, Reinhard, Levesque, Mitchell P, Schnetzler, Gabriel, Martoglio, Bruno, Bischoff, James R, Pettazzoni, Piergiorgio

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Discovery of Orally Available and Brain Penetrant AEP Inhibitors von Krummenacher, Daniela, He, Weiping, Kuhn, Bernd, Schnider, Christian, Beurier, Angélica, Brom, Virginie, Sivasothy, Thulase, Marty, Christine, Tosstorff, Andreas, Hewings, David S., Mesch, Stefanie, Pinard, Emmanuel, Brändlin, Mathis, Hochstrasser, Remo, Westwood, Paul, Rothe, Judith, Kronenberger, Alexandra, Morandi, Federica, Gutbier, Simon, Schuler, Angelika, Heer, Dominik, Gloria, Ludivine Esteves, Joedicke, Lisa, Rudolph, Markus G., Müller, Lutz, Grüninger, Fiona, Baumann, Karlheinz, Kaniyappan, Senthilvelrajan, Manevski, Nenad, Bartels, Björn

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Expanding the repertoire of GalNAc analogues for cell-specific bioorthogonal tagging of glycoproteins von Zafar, Abdul, Sridhar, Sandhya, Bineva-Todd, Ganka, Cioce, Anna, Abdulla, Nadia, Chang, Vincent, Malaker, Stacy A, Hewings, David S, Schumann, Benjamin

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Organocatalytic removal of formaldehyde adducts from RNA and DNA bases von Karmakar, Saswata, Harcourt, Emily M., Hewings, David S., Scherer, Florian, Lovejoy, Alexander F., Kurtz, David M., Ehrenschwender, Thomas, Barandun, Luzi J., Roost, Caroline, Alizadeh, Ash A., Kool, Eric T.

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The Colombian Economy and Its Regional Structural Challenges: A Linkages Approach von Haddad, Eduardo A, Bonet, Jaime, Hewings, Geoffrey J. D

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Isoxazole-Derived Amino Acids are Bromodomain-Binding Acetyl-Lysine Mimics: Incorporation into Histone H4 Peptides and Histone H3 von Sekirnik (née Measures), Angelina R., Hewings, David S., Theodoulou, Natalie H., Jursins, Lukass, Lewendon, Katie R., Jennings, Laura E., Rooney, Timothy P. C., Heightman, Tom D., Conway, Stuart J.

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The design and synthesis of 5- and 6-isoxazolylbenzimidazoles as selective inhibitors of the BET bromodomains von Hay, Duncan, Fedorov, Oleg, Filippakopoulos, Panagis, Martin, Sarah, Philpott, Martin, Picaud, Sarah, Hewings, David S, Uttakar, Sagar, Heightman, Tom D, Conway, Stuart J, Knapp, Stefan, Brennan, Paul E

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Fragment-Based Identification of Ligands for Bromodomain-Containing Factor 3 of Trypanosoma cruzi von Laurin, Corentine M. C, Bluck, Joseph P, Chan, Anthony K. N, Keller, Michelle, Boczek, Andrew, Scorah, Amy R, See, K. F. Larissa, Jennings, Laura E, Hewings, David S, Woodhouse, Fern, Reynolds, Jessica K, Schiedel, Matthias, Humphreys, Philip G, Biggin, Philip C, Conway, Stuart J

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