Organic Cation Transporter I and Na+/taurocholate Co‐Transporting Polypeptide are Involved in Retrorsine‐ and Senecionine‐Induced Hepatotoxicity in HepaRG cells von Enge, Anne‐Margarethe, Kaltner, Florian, Gottschalk, Christoph, Kin, Angelina, Kirstgen, Michael, Geyer, Joachim, These, Anja, Hammer, Helen, Pötz, Oliver, Braeuning, Albert, Hessel‐Pras, Stefanie

Volltext

Hepatotoxic pyrrolizidine alkaloids induce DNA damage response in rat liver in a 28-day feeding study von Ebmeyer, Johanna, Rasinger, Josef Daniel, Hengstler, Jan G., Schaudien, Dirk, Creutzenberg, Otto, Lampen, Alfonso, Braeuning, Albert, Hessel-Pras, Stefanie

Volltext

Sensitization of Human Liver Cells Toward Fas‐Mediated Apoptosis by the Metabolically Activated Pyrrolizidine Alkaloid Lasiocarpine von Ebmeyer, Johanna, Franz, Luise, Lim, Ramonique, Niemann, Birgit, Glatt, Hansruedi, Braeuning, Albert, Lampen, Alfonso, Hessel‐Pras, Stefanie

Volltext

Pyrrolizidine Alkaloids Induce Cell Death in Human HepaRG Cells in a Structure-Dependent Manner von Glück, Josephin, Waizenegger, Julia, Braeuning, Albert, Hessel-Pras, Stefanie

Volltext

Usage and health perception of cannabidiol-containing products among the population in Germany: a descriptive study conducted in 2020 and 2021 von Geppert, Johanna, Lietzow, Julika, Hessel-Pras, Stefanie, Kirsch, Fabian, Schäfer, Bernd, Sachse, Benjamin

Volltext

Structure-Dependent Toxicokinetics of Selected Pyrrolizidine Alkaloids In Vitro von Buchmueller, Julia, Kaltner, Florian, Gottschalk, Christoph, Maares, Maria, Braeuning, Albert, Hessel-Pras, Stefanie

Volltext

Active Transport of Hepatotoxic Pyrrolizidine Alkaloids in HepaRG Cells von Enge, Anne-Margarethe, Kaltner, Florian, Gottschalk, Christoph, Braeuning, Albert, Hessel-Pras, Stefanie

Volltext

Polycyclic Aromatic Hydrocarbons Activate the Aryl Hydrocarbon Receptor and the Constitutive Androstane Receptor to Regulate Xenobiotic Metabolism in Human Liver Cells von Goedtke, Lisa, Sprenger, Heike, Hofmann, Ute, Schmidt, Felix F, Hammer, Helen S, Zanger, Ulrich M, Poetz, Oliver, Seidel, Albrecht, Braeuning, Albert, Hessel-Pras, Stefanie

Volltext

The pyrrolizidine alkaloid senecionine induces CYP-dependent destruction of sinusoidal endothelial cells and cholestasis in mice von Hessel-Pras, Stefanie, Braeuning, Albert, Guenther, Georgia, Adawy, Alshaimaa, Enge, Anne-Margarethe, Ebmeyer, Johanna, Henderson, Colin J., Hengstler, Jan G., Lampen, Alfonso, Reif, Raymond

Volltext

Pyrrolizidine alkaloid-induced transcriptomic changes in rat lungs in a 28-day subacute feeding study von Buchmueller, Julia, Sprenger, Heike, Ebmeyer, Johanna, Rasinger, Josef Daniel, Creutzenberg, Otto, Schaudien, Dirk, Hengstler, Jan G., Guenther, Georgia, Braeuning, Albert, Hessel-Pras, Stefanie

Volltext

Results of the BfR MEAL Study: Acrylamide in foods from the German market with highest levels in vegetable crisps von Perestrelo, Sara, Schwerbel, Kristin, Hessel-Pras, Stefanie, Schäfer, Bernd, Kaminski, Martin, Lindtner, Oliver, Sarvan, Irmela

Volltext

The Food Contaminants Pyrrolizidine Alkaloids Disturb Bile Acid Homeostasis Structure-Dependently in the Human Hepatoma Cell Line HepaRG von Glück, Josephin, Henricsson, Marcus, Braeuning, Albert, Hessel-Pras, Stefanie

Volltext

Identification of microRNAs Implicated in Modulating Senecionine-Induced Liver Toxicity in HepaRG Cells von Enge, Anne-Margarethe, Sprenger, Heike, Braeuning, Albert, Hessel-Pras, Stefanie

Volltext

Pyrrolizidine Alkaloids Disturb Bile Acid Homeostasis in the Human Hepatoma Cell Line HepaRG von Waizenegger, Julia, Glück, Josephin, Henricsson, Marcus, Luckert, Claudia, Braeuning, Albert, Hessel-Pras, Stefanie

Volltext

Metabolism of the Marine Phycotoxin PTX-2 and Its Effects on Hepatic Xenobiotic Metabolism: Activation of Nuclear Receptors and Modulation of the Phase I Cytochrome P450 von Alarcan, Jimmy, Dubreil, Estelle, Huguet, Antoine, Hurtaud-Pessel, Dominique, Hessel-Pras, Stefanie, Lampen, Alfonso, Fessard, Valérie, Le Hegarat, Ludovic

Volltext

Human CYP3A4-mediated toxification of the pyrrolizidine alkaloid lasiocarpine von Ebmeyer, Johanna, Braeuning, Albert, Glatt, Hansruedi, These, Anja, Hessel-Pras, Stefanie, Lampen, Alfonso

Volltext

PXR: Structure-specific activation by hepatotoxic pyrrolizidine alkaloids von Luckert, Claudia, Braeuning, Albert, Lampen, Alfonso, Hessel-Pras, Stefanie

Volltext

Mixture effects of food-relevant polycyclic aromatic hydrocarbons on the activation of nuclear receptors and gene expression, benzo[a]pyrene metabolite profile and DNA damage in He... von Goedtke, Lisa, John, Andrea, Lampen, Alfonso, Seidel, Albrecht, Braeuning, Albert, Hessel-Pras, Stefanie

Volltext

Structure-dependent induction of apoptosis by hepatotoxic pyrrolizidine alkaloids in the human hepatoma cell line HepaRG: Single versus repeated exposure von Waizenegger, Julia, Braeuning, Albert, Templin, Markus, Lampen, Alfonso, Hessel-Pras, Stefanie

Volltext

Metabolism of okadaic acid by NADPH-dependent enzymes present in human or rat liver S9 fractions results in different toxic effects von Kolrep, Franziska, Rein, Kathleen, Lampen, Alfonso, Hessel-Pras, Stefanie

Volltext