Rogaratinib: A potent and selective pan‐FGFR inhibitor with broad antitumor activity in FGFR‐overexpressing preclinical cancer models von Grünewald, Sylvia, Politz, Oliver, Bender, Sebastian, Héroult, Mélanie, Lustig, Klemens, Thuss, Uwe, Kneip, Christoph, Kopitz, Charlotte, Zopf, Dieter, Collin, Marie‐Pierre, Boemer, Ulf, Ince, Stuart, Ellinghaus, Peter, Mumberg, Dominik, Hess‐Stumpp, Holger, Ziegelbauer, Karl

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BAY 87‐2243, a highly potent and selective inhibitor of hypoxia‐induced gene activation has antitumor activities by inhibition of mitochondrial complex I von Ellinghaus, Peter, Heisler, Iring, Unterschemmann, Kerstin, Haerter, Michael, Beck, Hartmut, Greschat, Susanne, Ehrmann, Alexander, Summer, Holger, Flamme, Ingo, Oehme, Felix, Thierauch, Karlheinz, Michels, Martin, Hess‐Stumpp, Holger, Ziegelbauer, Karl

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Discovery of Rogaratinib (BAY 1163877): a pan‐FGFR Inhibitor von Collin, Marie‐Pierre, Lobell, Mario, Hübsch, Walter, Brohm, Dirk, Schirok, Hartmut, Jautelat, Rolf, Lustig, Klemens, Bömer, Ulf, Vöhringer, Verena, Héroult, Mélanie, Grünewald, Sylvia, Hess‐Stumpp, Holger

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Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate von Bunse, Lukas, Pusch, Stefan, Bunse, Theresa, Sahm, Felix, Sanghvi, Khwab, Friedrich, Mirco, Alansary, Dalia, Sonner, Jana K., Green, Edward, Deumelandt, Katrin, Kilian, Michael, Neftel, Cyril, Uhlig, Stefanie, Kessler, Tobias, von Landenberg, Anna, Berghoff, Anna S., Marsh, Kelly, Steadman, Mya, Zhu, Dongwei, Nicolay, Brandon, Wiestler, Benedikt, Breckwoldt, Michael O., Al-Ali, Ruslan, Karcher-Bausch, Simone, Bozza, Matthias, Oezen, Iris, Kramer, Magdalena, Meyer, Jochen, Habel, Antje, Eisel, Jessica, Poschet, Gernot, Weller, Michael, Preusser, Matthias, Nadji-Ohl, Minou, Thon, Niklas, Burger, Michael C., Harter, Patrick N., Ratliff, Miriam, Harbottle, Richard, Benner, Axel, Schrimpf, Daniel, Okun, Jürgen, Herold-Mende, Christel, Turcan, Sevin, Kaulfuss, Stefan, Hess‐Stumpp, Holger, Bieback, Karen, Cahill, Daniel P., Plate, Karl H., Hänggi, Daniel, Dorsch, Marion, Suvà, Mario L., Niemeyer, Barbara A., von Deimling, Andreas, Wick, Wolfgang, Platten, Michael

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Pan-mutant IDH1 inhibitor BAY 1436032 for effective treatment of IDH1 mutant astrocytoma in vivo von Pusch, Stefan, Krausert, Sonja, Fischer, Viktoria, Balss, Jörg, Ott, Martina, Schrimpf, Daniel, Capper, David, Sahm, Felix, Eisel, Jessica, Beck, Ann-Christin, Jugold, Manfred, Eichwald, Viktoria, Kaulfuss, Stefan, Panknin, Olaf, Rehwinkel, Hartmut, Zimmermann, Katja, Hillig, Roman C., Guenther, Judith, Toschi, Luisella, Neuhaus, Roland, Haegebart, Andrea, Hess-Stumpp, Holger, Bauser, Markus, Wick, Wolfgang, Unterberg, Andreas, Herold-Mende, Christel, Platten, Michael, von Deimling, Andreas

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Mass cytometry analysis reveals a distinct immune environment in peritoneal fluid in endometriosis: a characterisation study von Guo, Manman, Bafligil, Cemsel, Tapmeier, Thomas, Hubbard, Carol, Manek, Sanjiv, Shang, Catherine, Martinez, Fernando O., Schmidt, Nicole, Obendorf, Maik, Hess-Stumpp, Holger, Zollner, Thomas M., Kennedy, Stephen, Becker, Christian M., Zondervan, Krina T., Cribbs, Adam P., Oppermann, Udo

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MS-275, a potent orally available inhibitor of histone deacetylases—The development of an anticancer agent von Hess-Stumpp, Holger, Bracker, Tomke Ute, Henderson, David, Politz, Oliver

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Histone deacetylase inhibitors and cancer: from cell biology to the clinic von Hess-Stumpp, Holger

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Lethal Poisoning of Cancer Cells by Respiratory Chain Inhibition plus Dimethyl α-Ketoglutarate von Sica, Valentina, Bravo-San Pedro, Jose Manuel, Izzo, Valentina, Pol, Jonathan, Pierredon, Sandra, Enot, David, Durand, Sylvère, Bossut, Noélie, Chery, Alexis, Souquere, Sylvie, Pierron, Gerard, Vartholomaiou, Evangelia, Zamzami, Naoufal, Soussi, Thierry, Sauvat, Allan, Mondragón, Laura, Kepp, Oliver, Galluzzi, Lorenzo, Martinou, Jean-Claude, Hess-Stumpp, Holger, Ziegelbauer, Karl, Kroemer, Guido, Maiuri, Maria Chiara

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Sagopilone crosses the blood-brain barrier in vivo to inhibit brain tumor growth and metastases von Hoffmann, Jens, Fichtner, Iduna, Lemm, Margit, Lienau, Philip, Hess-Stumpp, Holger, Rotgeri, Andrea, Hofmann, Birte, Klar, Ulrich

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Hypoxia-Inducible Factor Pathway Inhibition Resolves Tumor Hypoxia and Improves Local Tumor Control After Single-Dose Irradiation von Helbig, Linda, Koi, Lydia, PhD, Brüchner, Kerstin, PhD, Gurtner, Kristin, MD, Hess-Stumpp, Holger, PhD, Unterschemmann, Kerstin, PhD, Pruschy, Martin, PhD, Baumann, Michael, MD, PhD, Yaromina, Ala, PhD, Zips, Daniel, MD, PhD

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In vivo Properties of an Anti-GnRH Spiegelmer: An Example of an Oligonucleotide-Based Therapeutic Substance Class von Wlotzka, Britta, Leva, Susanne, Eschgfäller, Bernd, Burmeister, Jens, Kleinjung, Frank, Kaduk, Christine, Muhn, Peter, Hess-Stumpp, Holger, Klussmann, Sven

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PTK 787/ZK 222584, a Tyrosine Kinase Inhibitor of all Known VEGF Receptors, Represses Tumor Growth with High Efficacy von Hess-Stumpp, Holger, Haberey, Martin, Thierauch, Karl-Heinz

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Cycle-dependent endometrial expression and hormonal regulation of the fibulin-1 gene von Haendler, Bernard, Yamanouchi, Hiroshi, Lessey, Bruce A., Chwalisz, Kristof, Hess-Stumpp, Holger

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Inhibition of Hypoxia-Induced Gene Transcription by Substituted Pyrazolyl Oxadiazoles: Initial Lead Generation and Structure-Activity Relationships von Härter, Michael, Thierauch, Karl-Heinz, Boyer, Stephen, Bhargava, Ajay, Ellinghaus, Peter, Beck, Hartmut, Greschat-Schade, Susanne, Hess-Stumpp, Holger, Unterschemmann, Kerstin

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Cyr61, a deregulated gene in endometriosis von Absenger, Yvonne, Hess‐Stumpp, Holger, Kreft, Bertolt, Krätzschmar, Jörn, Haendler, Bernard, Schütze, Norbert, Regidor, Pedro‐Antonio, Winterhager, Elke

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Synthesis and Biological Activity of a Novel, Highly Potent Progesterone Receptor Antagonist von Fuhrmann, Ulrike, Hess-Stumpp, Holger, Cleve, Arwed, Neef, Günter, Schwede, Wolfgang, Hoffmann, Jens, Fritzemeier, Karl-Heinrich, Chwalisz, Kristof

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Abstract LB-244: BAY 87-2243, an inhibitor of HIF-1α - induced gene activation, showed promising anti-tumor efficacy in combination with anti-angiogenic therapy and irradiation in... von Hess-Stumpp, Holger

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Asoprisnil (J867): a selective progesterone receptor modulator for gynecological therapy von DeManno, Deborah, Elger, Walter, Garg, Ramesh, Lee, Ronald, Schneider, Birgitt, Hess-Stumpp, Holger, Schubert, Gerd, Chwalisz, Kristof

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Abstract 2182: Preclincial in vitro and in vivo combination therapies for mutant IDH1R132 tumors with BAY 1436032 von Kaulfuss, Stefan, Zaman, Julia, Chaturvedi, Anuhar, Hess-Stumpp, Holger, Höde, Jennifer, Biber, Ricarda, Borowicz, Renan, Heuser, Michael, Deimling, Andreas von, Pusch, Stefan

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