CBX8, a Polycomb Group Protein, Is Essential for MLL-AF9-Induced Leukemogenesis von Tan, Jiaying, Jones, Morgan, Koseki, Haruhiko, Nakayama, Manabu, Muntean, Andrew G., Maillard, Ivan, Hess, Jay L.

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Pharmacologic Inhibition of the Menin-MLL Interaction Blocks Progression of MLL Leukemia In Vivo von Borkin, Dmitry, He, Shihan, Miao, Hongzhi, Kempinska, Katarzyna, Pollock, Jonathan, Chase, Jennifer, Purohit, Trupta, Malik, Bhavna, Zhao, Ting, Wang, Jingya, Wen, Bo, Zong, Hongliang, Jones, Morgan, Danet-Desnoyers, Gwenn, Guzman, Monica L., Talpaz, Moshe, Bixby, Dale L., Sun, Duxin, Hess, Jay L., Muntean, Andrew G., Maillard, Ivan, Cierpicki, Tomasz, Grembecka, Jolanta

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Targeting MLL1 H3K4 Methyltransferase Activity in Mixed-Lineage Leukemia von Cao, Fang, Townsend, Elizabeth C., Karatas, Hacer, Xu, Jing, Li, Li, Lee, Shirley, Liu, Liu, Chen, Yong, Ouillette, Peter, Zhu, Jidong, Hess, Jay L., Atadja, Peter, Lei, Ming, Qin, Zhaohui S., Malek, Sami, Wang, Shaomeng, Dou, Yali

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The pathogenesis of mixed-lineage leukemia von Muntean, Andrew G, Hess, Jay L

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Deregulation of the HOXA9/MEIS1 axis in acute leukemia von Collins, Cailin T, Hess, Jay L

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HOXA9 Reprograms the Enhancer Landscape to Promote Leukemogenesis von Sun, Yuqing, Zhou, Bo, Mao, Fengbiao, Xu, Jing, Miao, Hongzhi, Zou, Zhenhua, Phuc Khoa, Le Tran, Jang, Younghoon, Cai, Sheng, Witkin, Matthew, Koche, Richard, Ge, Kai, Dressler, Gregory R., Levine, Ross L., Armstrong, Scott A., Dou, Yali, Hess, Jay L.

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MLL: a histone methyltransferase disrupted in leukemia von Hess, Jay L.

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Identification and characterization of Hoxa9 binding sites in hematopoietic cells von Huang, Yongsheng, Sitwala, Kajal, Bronstein, Joel, Sanders, Daniel, Dandekar, Monisha, Collins, Cailin, Robertson, Gordon, MacDonald, James, Cezard, Timothee, Bilenky, Misha, Thiessen, Nina, Zhao, Yongjun, Zeng, Thomas, Hirst, Martin, Hero, Alfred, Jones, Steven, Hess, Jay L.

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C/EBPα is an essential collaborator in Hoxa9/Meis1-mediated leukemogenesis von Collins, Cailin, Wang, Jingya, Miao, Hongzhi, Bronstein, Joel, Nawer, Humaira, Xu, Tao, Figueroa, Maria, Muntean, Andrew G., Hess, Jay L.

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MLL Associates with Telomeres and Regulates Telomeric Repeat-Containing RNA Transcription von Caslini, Corrado, Connelly, James A., Serna, Amparo, Broccoli, Dominique, Hess, Jay L.

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Mechanisms of transcriptional regulation by MLL and its disruption in acute leukemia von Dou, Yali, Hess, Jay L.

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The PAF Complex Synergizes with MLL Fusion Proteins at HOX Loci to Promote Leukemogenesis von Muntean, Andrew G., Tan, Jiaying, Sitwala, Kajal, Huang, Yongsheng, Bronstein, Joel, Connelly, James A., Basrur, Venkatesha, Elenitoba-Johnson, Kojo S.J., Hess, Jay L.

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MLL-ENL Inhibits Polycomb Repressive Complex 1 to Achieve Efficient Transformation of Hematopoietic Cells von Maethner, Emanuel, Garcia-Cuellar, Maria-Paz, Breitinger, Constanze, Takacova, Sylvia, Divoky, Vladimir, Hess, Jay L., Slany, Robert K.

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ECSASB2 mediates MLL degradation during hematopoietic differentiation von Wang, Jingya, Muntean, Andrew G., Hess, Jay L.

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The protective role of DOT1L in UV-induced melanomagenesis von Zhu, Bo, Chen, Shuyang, Wang, Hongshen, Yin, Chengqian, Han, Changpeng, Peng, Cong, Liu, Zhaoqian, Wan, Lixin, Zhang, Xiaoyang, Zhang, Jie, Lian, Christine G., Ma, Peilin, Xu, Zhi-xiang, Prince, Sharon, Wang, Tao, Gao, Xiumei, Shi, Yujiang, Liu, Dali, Liu, Min, Wei, Wenyi, Wei, Zhi, Pan, Jingxuan, Wang, Yongjun, Xuan, Zhenyu, Hess, Jay, Hayward, Nicholas K., Goding, Colin R., Chen, Xiang, Zhou, Jun, Cui, Rutao

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Loss-of-function Additional sex combs like 1 mutations disrupt hematopoiesis but do not cause severe myelodysplasia or leukemia von Fisher, Cynthia L., Pineault, Nicolas, Brookes, Christy, Helgason, Cheryl D., Ohta, Hideaki, Bodner, Caroline, Hess, Jay L., Humphries, R. Keith, Brock, Hugh W.

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Menin and MLL Cooperatively Regulate Expression of Cyclin-Dependent Kinase Inhibitors von Milne, Thomas A., Hughes, Christina M., Lloyd, Ricardo, Yang, Zhaohai, Rozenblatt-Rosen, Orit, Dou, Yali, Schnepp, Robert W., Krankel, Cynthia, LiVolsi, Virginia A., Gibbs, Denise, Hua, Xianxin, Roeder, Robert G., Meyerson, Matthew, Hess, Jay L.

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The same site on the integrase-binding domain of lens epithelium–derived growth factor is a therapeutic target for MLL leukemia and HIV von Murai, Marcelo J., Pollock, Jonathan, He, Shihan, Miao, Hongzhi, Purohit, Trupta, Yokom, Adam, Hess, Jay L., Muntean, Andrew G., Grembecka, Jolanta, Cierpicki, Tomasz

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Targeting recruitment of disruptor of telomeric silencing 1-like (DOT1L): characterizing the interactions between DOT1L and mixed lineage leukemia (MLL) fusion proteins von Shen, Chenxi, Jo, Stephanie Y, Liao, Chenzhong, Hess, Jay L, Nikolovska-Coleska, Zaneta

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MLL Associates Specifically with a Subset of Transcriptionally Active Target Genes von Milne, Thomas A., Dou, Yali, Mary Ellen Martin, Brock, Hugh W., Roeder, Robert G., Hess, Jay L.

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