ALDH1A3 is epigenetically regulated during melanocyte transformation and is a target for melanoma treatment von Pérez-Alea, M, McGrail, K, Sánchez-Redondo, S, Ferrer, B, Fournet, G, Cortés, J, Muñoz, E, Hernandez-Losa, J, Tenbaum, S, Martin, G, Costello, R, Ceylan, I, Garcia-Patos, V, Recio, J A

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Phenformin-induced mitochondrial dysfunction sensitizes hepatocellular carcinoma for dual inhibition of mTOR von Veiga, S., Ge, X., Mercer, C., Hernández-Álvarez, M., Thomas, H., Hernandez-Losa, J., Cajal, S.R.Y, Zorzano, A., Thomas, G., Kozma, S.

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3001 Prevalence and clinical association of gene mutations through Multiplex Mutation Testing in patients with NSCLC: Results from the ETOP Lungscape Project von Kerr, K, Dafni, U, Schulze, K, Thunnissen, E, Bubendorf, L, Hager, H, Gately, K, Biernat, W, Vliegen, L, Hernandez Losa, J, Marchetti, A, Cheney, R, Warth, A, Speel, E.J, Blackhall, F, Molina, M.A, Shames, D.S, Peters, S, Stahel, R

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Update of the recommendations for the determination of biomarkers in colorectal carcinoma: National Consensus of the Spanish Society of Medical Oncology and the Spanish Society of... von García-Alfonso, P., García-Carbonero, R., García-Foncillas, J., Pérez-Segura, P., Salazar, R., Vera, R., Ramón y Cajal, S., Hernández-Losa, J., Landolfi, S., Musulén, E., Cuatrecasas, M., Navarro, S.

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676 HER3 Expression in Human Breast Carcinomas is Associated With Tumor Size and Estrogen Receptor Status von Teixido, C, Peg, V, Moline, T, Pandiella, A, Saura, C, Somoza, R, Mares, R, y Cajal, S. Ramon, Hernandez-Losa, J

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Spiny hyperkeratosis (trichodysplasia spinulosa‐like eruption): a cutaneous adverse effect of Hedgehog pathway inhibitors involving expression of p16 von López‐Lerma, I., Ferrer, B., Zarzoso, I., Hernández‐Losa, J., García‐Patos, V.

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S-adenosylhomocysteine hydrolase downregulation contributes to tumorigenesis von Leal, J.F., Ferrer, I., Blanco-Aparicio, C., Hernández-Losa, J., Ramón y Cajal, S., Carnero, A., LLeonart, M.E.

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ErbBs inhibition by lapatinib blocks tumor growth in an orthotopic model of human testicular germ cell tumor von Juliachs, M., Castillo‐Ávila, W., Vidal, A., Piulats, J.M., Garcia del Muro, X., Condom, E., Hernández‐Losa, J., Teixidó, C., Pandiella, A., Graupera, M., Casanovas, O., Germà, J.R., Villanueva, A., Viñals, F.

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Cancer as an ecomolecular disease and a neoplastic consortium von Ramón y Cajal, Santiago, Capdevila, Claudia, Hernandez-Losa, Javier, De Mattos-Arruda, Leticia, Ghosh, Abhishek, Lorent, Julie, Larsson, Ola, Aasen, Trond, Postovit, Lynne-Marie, Topisirovic, Ivan

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The patient has the diagnosis von Jubany, LI, MD, Selva-O'Callaghan, A, Dr, Pérez-Vega, C, MD, Grau-Junyent, JM, Prof, Hernández-Losa, J, PhD, Vilardell-Tarrés, M, Prof

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Stem cell-like transcriptional reprogramming mediates metastatic resistance to mTOR inhibition von Mateo, F, Arenas, E J, Aguilar, H, Serra-Musach, J, de Garibay, G Ruiz, Boni, J, Maicas, M, Du, S, Iorio, F, Herranz-Ors, C, Islam, A, Prado, X, Llorente, A, Petit, A, Vidal, A, Català, I, Soler, T, Venturas, G, Rojo-Sebastian, A, Serra, H, Cuadras, D, Blanco, I, Lozano, J, Canals, F, Sieuwerts, A M, de Weerd, V, Look, M P, Puertas, S, García, N, Perkins, A S, Bonifaci, N, Skowron, M, Gómez-Baldó, L, Hernández, V, Martínez-Aranda, A, Martínez-Iniesta, M, Serrat, X, Cerón, J, Brunet, J, Barretina, M P, Gil, M, Falo, C, Fernández, A, Morilla, I, Pernas, S, Plà, M J, Andreu, X, Seguí, M A, Ballester, R, Castellà, E, Nellist, M, Morales, S, Valls, J, Velasco, A, Matias-Guiu, X, Figueras, A, Sánchez-Mut, J V, Sánchez-Céspedes, M, Cordero, A, Gómez-Miragaya, J, Palomero, L, Gómez, A, Gajewski, T F, Cohen, E E W, Jesiotr, M, Bodnar, L, Quintela-Fandino, M, López-Bigas, N, Valdés-Mas, R, Puente, X S, Viñals, F, Casanovas, O, Graupera, M, Hernández-Losa, J, Ramón y Cajal, S, García-Alonso, L, Saez-Rodriguez, J, Esteller, M, Sierra, A, Martín-Martín, N, Matheu, A, Carracedo, A, González-Suárez, E, Nanjundan, M, Cortés, J, Lázaro, C, Odero, M D, Martens, J W M, Moreno-Bueno, G, Barcellos-Hoff, M H, Villanueva, A, Gomis, R R, Pujana, M A

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The umbilical cord, preeclampsia and the VEGF family von Olaya-C, Mercedes, Garrido, Marta, Hernandez-Losa, Javier, Sesé, Marta, Ayala-Ramirez, Paola, Somoza, Rosa, Vargas, Magda Jimena, Ramón Y Cajal, Santiago

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Regulation of the transcriptional activity of c-Fos by ERK. A novel role for the prolyl isomerase PIN1 von Monje, Paula, Hernández-Losa, Javier, Lyons, Ruth J, Castellone, Maria D, Gutkind, J Silvio

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2223P Next-generation sequencing enables identification of RET rearrangements in papillary thyroid cancer von Clavé, S., Sese, M., Somoza, R., Arumí, M., Iglesias, C., Hernando, J., Garcia Alvarez, A., Lloveras, B., Guix Arnau, M., Capdevila Castillon, J., Bellosillo Paricio, B., Hernandez-Losa, J.

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Lack of association of polyomavirus and herpesvirus types 6 and 7 in human lymphomas von Hernández‐Losa, Javier, Fedele, Cesar Giovanni, Pozo, Francisco, Tenorio, Antonio, Fernández, Victor, Castellví, Josep, Parada, Carlos, Ramón y Cajal, Santiago

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684 Phosphorylation of EIF4E Enhances Survival and Growth Under Stress Conditions von Martinez, A, Sese, M, Hernández-Losa, J, Peg, V, Aasen, T, y Cajal, S. Ramon

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1925P DNA methylation signature for prediction of metastasis and response to multikinase inhibitors of differentiated thyroid carcinoma (DTC) von Hernando, J., Zafon, C., Diez-Villanueva, A., Iglesias, C., Rodriguez, H., Villalmazo, N., Gil, J., Klein-Hesselink, E., Roca, M., Verdaguer, H., Acosta Eyzaguirre, D.A., Diez Garcia, M., Lindo, E., Hernandez-Losa, J., Reverter, J., Puig-Domingo, M., Links, T., Capdevila, J., Jordà, M.

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P-324Phenformin-induced mitochondrial dysfunction sensitizes hepatocellular carcinoma for dual inhibition of mTOR von Veiga, S, Ge, X, Mercer, C, Hernández-Álvarez, M, Thomas, H, Hernandez-Losa, J, Cajal, SR Y, Zorzano, A, Thomas, G, Kozma, S

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RSK4 inhibition results in bypass of stress-induced and oncogene-induced senescence von LOPEZ-VICENTE, Laura, PONS, Berta, COCH, Laura, TEIXIDO, Cristina, HERNANDEZ-LOSA, Javier, ARMENGOL, Gemma, RAMON Y CAJAL, Santiago

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125PComparison of different testing methods for detection of BRAF V600 mutation in metastatic melanoma von Hernandez-Losa, J, Ruano, Y, Trigo Sanchez, I, Somoza, R, Ferrer, B, Garcia Verdes-Montenegro, F, Urech, M, Ramon, S, Cajal, Y, Rios Martin, J J, Rodriguez-Peralto, J L

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