The ACMG SF v3.0 gene list increases returnable variant detection by 22% when compared with v2.0 in the ClinSeq cohort von Johnston, Jennifer J., Brennan, Marie-Luise, Radenbaugh, Bailey, Yoo, Seeley J., Hernandez, Sophia M., Lewis, Katie L., Katz, Alexander E., Manolio, Teri A., Biesecker, Leslie G.

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Massive contractions of myotonic dystrophy type 2-associated CCTG tetranucleotide repeats occur via double-strand break repair with distinct requirements for DNA helicases von Papp, David, Hernandez, Luis A, Mai, Theresa A, Haanen, Terrance J, O’Donnell, Meghan A, Duran, Ariel T, Hernandez, Sophia M, Narvanto, Jenni E, Arguello, Berenice, Onwukwe, Marvin O, Mirkin, Sergei M, Kim, Jane C

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Draft Genome Sequences of Bacillus glennii V44-8, Bacillus saganii V47-23a, Bacillus sp. Strain V59.32b, Bacillus sp. Strain MER_TA_151, and Paenibacillus sp. Strain MER_111, Isola... von Becket, Elinne, Johnson, Keneshia O, Burke, Camille J, Clark, Jasmin J, Cohen, Marcus J S, Coil, David A, Eggleston, Courtney A, Farmer, Tyesha L, Farr, Tiffany R, Hernandez, Sophia M, Jaureguy, Jeff P, Jospin, Guillaume, Khan, Afshin, Lee, Michael D, McKee, Lauren N, O'Brien, Erin M, Read, Betsy A, Saisho, Roxane, Seuylemezian, Arman, Serrato-Arroyo, Sergio S, Steinecke, Dylan, Vaishampayan, Parag

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Multiregional single-cell dissection of tumor and immune cells reveals stable lock-and-key features in liver cancer von Ma, Lichun, Heinrich, Sophia, Wang, Limin, Keggenhoff, Friederike L., Khatib, Subreen, Forgues, Marshonna, Kelly, Michael, Hewitt, Stephen M., Saif, Areeba, Hernandez, Jonathan M., Mabry, Donna, Kloeckner, Roman, Greten, Tim F., Chaisaingmongkol, Jittiporn, Ruchirawat, Mathuros, Marquardt, Jens U., Wang, Xin Wei

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Single-cell atlas of tumor cell evolution in response to therapy in hepatocellular carcinoma and intrahepatic cholangiocarcinoma von Ma, Lichun, Wang, Limin, Khatib, Subreen A., Chang, Ching-Wen, Heinrich, Sophia, Dominguez, Dana A., Forgues, Marshonna, Candia, Julián, Hernandez, Maria O., Kelly, Michael, Zhao, Yongmei, Tran, Bao, Hernandez, Jonathan M., Davis, Jeremy L., Kleiner, David E., Wood, Bradford J., Greten, Tim F., Wang, Xin Wei

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WNT11-FZD7-DAAM1 signalling supports tumour initiating abilities and melanoma amoeboid invasion von Rodriguez-Hernandez, Irene, Maiques, Oscar, Kohlhammer, Leonie, Cantelli, Gaia, Perdrix-Rosell, Anna, Monger, Joanne, Fanshawe, Bruce, Bridgeman, Victoria L., Karagiannis, Sophia N., Penin, Rosa M., Marcolval, Joaquim, Marti, Rosa M., Matias-Guiu, Xavier, Fruhwirth, Gilbert O., Orgaz, Jose L., Malanchi, Ilaria, Sanz-Moreno, Victoria

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Identification of apilimod as a first-in-class PIKfyve kinase inhibitor for treatment of B-cell non-Hodgkin lymphoma von Gayle, Sophia, Landrette, Sean, Beeharry, Neil, Conrad, Chris, Hernandez, Marylens, Beckett, Paul, Ferguson, Shawn M., Mandelkern, Talya, Zheng, Meiling, Xu, Tian, Rothberg, Jonathan, Lichenstein, Henri

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Neurologic phenotypes associated with COL4A1/2 mutations: Expanding the spectrum of disease von Zagaglia, Sara, Selch, Christina, Nisevic, Jelena Radic, Mei, Davide, Michalak, Zuzanna, Hernandez-Hernandez, Laura, Krithika, S, Vezyroglou, Katharina, Varadkar, Sophia M, Pepler, Alexander, Biskup, Saskia, Leão, Miguel, Gärtner, Jutta, Merkenschlager, Andreas, Jaksch, Michaela, Møller, Rikke S, Gardella, Elena, Kristiansen, Britta Schlott, Hansen, Lars Kjærsgaard, Vari, Maria Stella, Helbig, Katherine L, Desai, Sonal, Smith-Hicks, Constance L, Hino-Fukuyo, Naomi, Talvik, Tiina, Laugesaar, Rael, Ilves, Pilvi, Õunap, Katrin, Körber, Ingrid, Hartlieb, Till, Kudernatsch, Manfred, Winkler, Peter, Schimmel, Mareike, Hasse, Anette, Knuf, Markus, Heinemeyer, Jan, Makowski, Christine, Ghedia, Sondhya, Subramanian, Gopinath M, Striano, Pasquale, Thomas, Rhys H, Micallef, Caroline, Thom, Maria, Werring, David J, Kluger, Gerhard Josef, Cross, J Helen, Guerrini, Renzo, Balestrini, Simona, Sisodiya, Sanjay M

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BMI trajectories from birth to young adulthood associate with distinct cardiometabolic profiles von Wang, Gang, Wei, Dang, Kebede Merid, Simon, Ekström, Sandra, Klevebro, Susanna, Hernandez-Pacheco, Natalia, Björkander, Sophia, Ljungman, Petter, Kull, Inger, Schwenk, Jochen M, Bergström, Anna, Melén, Erik

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Proton stopping measurements at low velocity in warm dense carbon von Malko, S., Cayzac, W., Ospina-Bohórquez, V., Bhutwala, K., Bailly-Grandvaux, M., McGuffey, C., Fedosejevs, R., Vaisseau, X., Tauschwitz, An, Apiñaniz, J. I., De Luis Blanco, D., Gatti, G., Huault, M., Hernandez, J. A. Perez, Hu, S. X., White, A. J., Collins, L. A., Nichols, K., Neumayer, P., Faussurier, G., Vorberger, J., Prestopino, G., Verona, C., Santos, J. J., Batani, D., Beg, F. N., Roso, L., Volpe, L.

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Exploring proteomic plasma biomarkers in eosinophilic and neutrophilic asthma von Kere, Maura, Klevebro, Susanna, Hernandez‐Pacheco, Natalia, Ödling, Maria, Ekström, Sandra, Mogensen, Ida, Janson, Christer, Palmberg, Lena, Hage, Marianne, Georgelis, Antonios, Bergström, Anna, Kull, Inger, Melén, Erik, Björkander, Sophia

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TGF-β-Induced Transcription Sustains Amoeboid Melanoma Migration and Dissemination von Cantelli, Gaia, Orgaz, Jose L., Rodriguez-Hernandez, Irene, Karagiannis, Panagiotis, Maiques, Oscar, Matias-Guiu, Xavier, Nestle, Frank O., Marti, Rosa M., Karagiannis, Sophia N., Sanz-Moreno, Victoria

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Regional Activation of Myosin II in Cancer Cells Drives Tumor Progression via a Secretory Cross-Talk with the Immune Microenvironment von Georgouli, Mirella, Herraiz, Cecilia, Crosas-Molist, Eva, Fanshawe, Bruce, Maiques, Oscar, Perdrix, Anna, Pandya, Pahini, Rodriguez-Hernandez, Irene, Ilieva, Kristina M., Cantelli, Gaia, Karagiannis, Panagiotis, Mele, Silvia, Lam, Hoyin, Josephs, Debra H., Matias-Guiu, Xavier, Marti, Rosa M., Nestle, Frank O., Orgaz, Jose L., Malanchi, Ilaria, Fruhwirth, Gilbert O., Karagiannis, Sophia N., Sanz-Moreno, Victoria

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Brain Structure and Degeneration Staging in Friedreich Ataxia: Magnetic Resonance Imaging Volumetrics from the ENIGMA‐Ataxia Working Group von Harding, Ian H., Chopra, Sidhant, Arrigoni, Filippo, Boesch, Sylvia, Brunetti, Arturo, Cocozza, Sirio, Corben, Louise A., Deistung, Andreas, Delatycki, Martin, Diciotti, Stefano, Dogan, Imis, Evangelisti, Stefania, França, Marcondes C., Göricke, Sophia L., Georgiou‐Karistianis, Nellie, Gramegna, Laura L., Henry, Pierre‐Gilles, Hernandez‐Castillo, Carlos R., Hutter, Diane, Jahanshad, Neda, Joers, James M., Lenglet, Christophe, Lodi, Raffaele, Manners, David N., Martinez, Alberto R. M., Martinuzzi, Andrea, Marzi, Chiara, Mascalchi, Mario, Nachbauer, Wolfgang, Pane, Chiara, Peruzzo, Denis, Pisharady, Pramod K., Pontillo, Giuseppe, Reetz, Kathrin, Rezende, Thiago J. R., Romanzetti, Sandro, Saccà, Francesco, Scherfler, Christoph, Schulz, Jörg B., Stefani, Ambra, Testa, Claudia, Thomopoulos, Sophia I., Timmann, Dagmar, Tirelli, Stefania, Tonon, Caterina, Vavla, Marinela, Egan, Gary F., Thompson, Paul M.

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Deep Learning Approaches for Predicting Glaucoma Progression Using Electronic Health Records and Natural Language Processing von Wang, Sophia Y., Tseng, Benjamin, Hernandez-Boussard, Tina

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The effects of metabolic syndrome, obesity, and the gut microbiome on load-induced osteoarthritis von Guss, J.D., Ziemian, S.N., Luna, M., Sandoval, T.N., Holyoak, D.T., Guisado, G.G., Roubert, S., Callahan, R.L., Brito, I.L., van der Meulen, M.C.H., Goldring, S.R., Hernandez, C.J.

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The Global Phosphorylation Landscape of SARS-CoV-2 Infection von Bouhaddou, Mehdi, Memon, Danish, Meyer, Bjoern, White, Kris M., Rezelj, Veronica V., Correa Marrero, Miguel, Polacco, Benjamin J., Melnyk, James E., Ulferts, Svenja, Kaake, Robyn M., Batra, Jyoti, Richards, Alicia L., Stevenson, Erica, Gordon, David E., Rojc, Ajda, Obernier, Kirsten, Fabius, Jacqueline M., Soucheray, Margaret, Miorin, Lisa, Moreno, Elena, Koh, Cassandra, Tran, Quang Dinh, Hardy, Alexandra, Robinot, Rémy, Vallet, Thomas, Nilsson-Payant, Benjamin E., Hernandez-Armenta, Claudia, Dunham, Alistair, Weigang, Sebastian, Knerr, Julian, Modak, Maya, Quintero, Diego, Zhou, Yuan, Dugourd, Aurelien, Valdeolivas, Alberto, Patil, Trupti, Li, Qiongyu, Hüttenhain, Ruth, Cakir, Merve, Muralidharan, Monita, Kim, Minkyu, Jang, Gwendolyn, Tutuncuoglu, Beril, Hiatt, Joseph, Guo, Jeffrey Z., Xu, Jiewei, Bouhaddou, Sophia, Mathy, Christopher J.P., Gaulton, Anna, Manners, Emma J., Félix, Eloy, Shi, Ying, Goff, Marisa, Lim, Jean K., McBride, Timothy, O’Neal, Michael C., Cai, Yiming, Chang, Jason C.J., Broadhurst, David J., Klippsten, Saker, De wit, Emmie, Leach, Andrew R., Kortemme, Tanja, Shoichet, Brian, Ott, Melanie, Saez-Rodriguez, Julio, tenOever, Benjamin R., Mullins, R. Dyche, Fischer, Elizabeth R., Kochs, Georg, Grosse, Robert, García-Sastre, Adolfo, Vignuzzi, Marco, Johnson, Jeffery R., Shokat, Kevan M., Swaney, Danielle L., Beltrao, Pedro, Krogan, Nevan J.

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High-purity preparation of HSV-2 vaccine candidate ACAM529 is immunogenic and efficacious in vivo von Mundle, Sophia T, Hernandez, Hector, Hamberger, John, Catalan, John, Zhou, Changhong, Stegalkina, Svetlana, Tiffany, Andrea, Kleanthous, Harry, Delagrave, Simon, Anderson, Stephen F

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Hormonal profiles and biomarkers leading to parturition in cattle von Monteiro, Pedo L J, Wiltbank, Milo C, Frizzarini, Waneska S, Andrade, João Paulo N, Cabrera, Elisa M, Schoenfeld, Sophia G, Domingues, Rafael R, Hernandez, Laura L

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Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B.1.1.7 von Curran, Martin D., Roy, Sunando, Shaaban, Sharif, de Cesare, Mariateresa, Stark, Richard, Palmer, Steve, Jeffries, Aaron R., da Silva Filipe, Ana, Davis, Thomas, Collins, Jennifer, Williams, Thomas, Haldenby, Sam T., Cook, Kate, Davies, Robert, Kay, Sally, Poplawski, Radoslaw, Reynolds, Nicola, Moll, Robin J., Thornton, Alicia, Gatica-Wilcox, Bree, Louka, Stavroula F., Kraemer, Moritz U.G., Freeman, Timothy M., Abudahab, Khalil, Menegazzo, Mirko, Mason, Jenifer, Holmes, Alison, Curran, Tanya, Mookerjee, Siddharth, Munn, Robert, Davies, Alisha, Smith, Nikki, Cormie, Claire, Lo, Stephanie, Auckland, Cressida, Mollett, Guy, Harper, Katherine L., Bonner, Stephen, Padgett, Debra, Burton-Fanning, Shirelle, Bedford, Luke, Coupland, Lindsay, Wright, Victoria, Ball, Jonathan, Boswell, Tim, Duckworth, Nichola, Williams, Rebecca, Cogger, Benjamin J., Farr, Ben W., Thurston, Scott A.J., Bronner, Iraad F., Aigrain, Louise, Gallagher, Michael D., Miah, Shahjahan, Ramsay, Mary, Schaefer, Ulf, Manesis, Nikos, Allara, Elias, Nichols, Jenna, Vamos, Edith E., Hughes, Margaret, Wilson, Harry D., Wilson, Rebekah E., Thompson, Thomas, O’Brien, Sarah, Rudder, Steven, McCluggage, Kathryn, Bonfield, James, Liddle, Jennifier, Rowe, Will, Bevan, Paul, Clark, Richard, Cutts, Tim, Densem, Aiden, Dodd, David, Griffiths, Coline, Kay, Keely, Lensing, Stefanie, Lewis-Wade, Amanah, Mamun, Irfan, Martin, Matt, McClintock, Jo, Nathwani, Claire, Nicholson, Jon, Patel, Gaurang, Petersen, Arabella, Reynolds, Joe, Rudd, Luke, Sadri, Ramin, Sizer, Dale, Soria, Carmen Diaz, Sousa, Catarina, Squares, Janet, Stickland, Tim, Still, Ian, Symons, Edward, Uphill, James, Van, Philip Jansen, Voak, Paul, Corti, Davide

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