Genetics in Parkinson disease: Mendelian versus non‐Mendelian inheritance von Hernandez, Dena G., Reed, Xylena, Singleton, Andrew B.

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Abundant quantitative trait loci exist for DNA methylation and gene expression in human brain von Gibbs, J Raphael, van der Brug, Marcel P, Hernandez, Dena G, Traynor, Bryan J, Nalls, Michael A, Lai, Shiao-Lin, Arepalli, Sampath, Dillman, Allissa, Rafferty, Ian P, Troncoso, Juan, Johnson, Robert, Zielke, H Ronald, Ferrucci, Luigi, Longo, Dan L, Cookson, Mark R, Singleton, Andrew B

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Parkinson's disease age at onset genome‐wide association study: Defining heritability, genetic loci, and α‐synuclein mechanisms von Blauwendraat, Cornelis, Heilbron, Karl, Vallerga, Costanza L., Bandres‐Ciga, Sara, von Coelln, Rainer, Pihlstrøm, Lasse, Simón‐Sánchez, Javier, Schulte, Claudia, Sharma, Manu, Krohn, Lynne, Siitonen, Ari, Iwaki, Hirotaka, Leonard, Hampton, Noyce, Alastair J., Tan, Manuela, Gibbs, J. Raphael, Hernandez, Dena G., Scholz, Sonja W., Jankovic, Joseph, Shulman, Lisa M., Lesage, Suzanne, Corvol, Jean‐Christophe, Brice, Alexis, van Hilten, Jacobus J., Marinus, Johan, Eerola‐Rautio, Johanna, Tienari, Pentti, Majamaa, Kari, Toft, Mathias, Grosset, Donald G., Gasser, Thomas, Heutink, Peter, Shulman, Joshua M., Wood, Nicolas, Hardy, John, Morris, Huw R., Hinds, David A., Gratten, Jacob, Visscher, Peter M., Gan‐Or, Ziv, Nalls, Mike A., Singleton, Andrew B.

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Menopause accelerates biological aging von Levine, Morgan E., Lu, Ake T., Chen, Brian H., Hernandez, Dena G., Singleton, Andrew B., Ferrucci, Luigi, Bandinelli, Stefania, Salfati, Elias, Manson, JoAnn E., Quach, Austin, Kusters, Cynthia D. J., Kuh, Diana, Wong, Andrew, Teschendorff, Andrew E., Widschwendter, Martin, Ritz, Beate R., Absher, Devin, Assimes, Themistocles L., Horvath, Steve

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Chromosome 9p21 in amyotrophic lateral sclerosis in Finland: a genome-wide association study von Laaksovirta, Hannu, MD, Peuralinna, Terhi, MSc, Schymick, Jennifer C, PhD, Scholz, Sonja W, MD, Lai, Shaoi-Lin, MD, Myllykangas, Liisa, MD, Sulkava, Raimo, MD, Jansson, Lilja, Hernandez, Dena G, MSc, Gibbs, J Raphael, BS, Nalls, Michael A, PhD, Heckerman, David, MD, Tienari, Pentti J, MD, Traynor, Bryan J, Dr

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A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD von Renton, Alan E., Majounie, Elisa, Waite, Adrian, Simón-Sánchez, Javier, Rollinson, Sara, Gibbs, J. Raphael, Schymick, Jennifer C., Laaksovirta, Hannu, van Swieten, John C., Myllykangas, Liisa, Kalimo, Hannu, Paetau, Anders, Abramzon, Yevgeniya, Remes, Anne M., Kaganovich, Alice, Scholz, Sonja W., Duckworth, Jamie, Ding, Jinhui, Harmer, Daniel W., Hernandez, Dena G., Johnson, Janel O., Mok, Kin, Ryten, Mina, Trabzuni, Danyah, Guerreiro, Rita J., Orrell, Richard W., Neal, James, Murray, Alex, Pearson, Justin, Jansen, Iris E., Sondervan, David, Seelaar, Harro, Blake, Derek, Young, Kate, Halliwell, Nicola, Callister, Janis Bennion, Toulson, Greg, Richardson, Anna, Gerhard, Alex, Snowden, Julie, Mann, David, Neary, David, Nalls, Michael A., Peuralinna, Terhi, Jansson, Lilja, Isoviita, Veli-Matti, Kaivorinne, Anna-Lotta, Hölttä-Vuori, Maarit, Ikonen, Elina, Sulkava, Raimo, Benatar, Michael, Wuu, Joanne, Chiò, Adriano, Restagno, Gabriella, Borghero, Giuseppe, Sabatelli, Mario, Heckerman, David, Rogaeva, Ekaterina, Zinman, Lorne, Rothstein, Jeffrey D., Sendtner, Michael, Drepper, Carsten, Eichler, Evan E., Alkan, Can, Abdullaev, Ziedulla, Pack, Svetlana D., Dutra, Amalia, Pak, Evgenia, Hardy, John, Singleton, Andrew, Williams, Nigel M., Heutink, Peter, Pickering-Brown, Stuart, Morris, Huw R., Tienari, Pentti J., Traynor, Bryan J.

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A whole-blood transcriptome meta-analysis identifies gene expression signatures of cigarette smoking von Huan, Tianxiao, Joehanes, Roby, Schurmann, Claudia, Schramm, Katharina, Pilling, Luke C, Peters, Marjolein J, Mägi, Reedik, DeMeo, Dawn, O'Connor, George T, Ferrucci, Luigi, Teumer, Alexander, Homuth, Georg, Biffar, Reiner, Völker, Uwe, Herder, Christian, Waldenberger, Melanie, Peters, Annette, Zeilinger, Sonja, Metspalu, Andres, Hofman, Albert, Uitterlinden, André G, Hernandez, Dena G, Singleton, Andrew B, Bandinelli, Stefania, Munson, Peter J, Lin, Honghuang, Benjamin, Emelia J, Esko, Tõnu, Grabe, Hans J, Prokisch, Holger, van Meurs, Joyce B J, Melzer, David, Levy, Daniel

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Genetic modifiers of risk and age at onset in GBA associated Parkinson's disease and Lewy body dementia von Blauwendraat, Cornelis, Reed, Xylena, Krohn, Lynne, Heilbron, Karl, Bandres-Ciga, Sara, Tan, Manuela, Gibbs, J. Raphael, Hernandez, Dena G., Kumaran, Ravindran, Langston, Rebekah, Bonet-Ponce, Luis, Alcalay, Roy N., Hassin-Baer, Sharon, Greenbaum, Lior, Iwaki, Hirotaka, Leonard, Hampton L., Grenn, Francis P., Ruskey, Jennifer A., Sabir, Marya, Ahmed, Sarah, Makarious, Mary B., Pihlstrom, Lasse, Toft, Mathias, van Hilten, Jacobus J., Marinus, Johan, Schulte, Claudia, Brockmann, Kathrin, Sharma, Manu, Siitonen, Ari, Majamaa, Kari, Eerola-Rautio, Johanna, Tienari, Pentti J., Pantelyat, Alexander, Hillis, Argye E., Dawson, Ted M., Rosenthal, Liana S., Albert, Marilyn S., Resnick, Susan M., Ferrucci, Luigi, Morris, Christopher M., Pletnikova, Olga, Troncoso, Juan, Grosset, Donald, Lesage, Suzanne, Corvol, Jean-Christophe, Brice, Alexis, Noyce, Alastair J., Masliah, Eliezer, Wood, Nick, Hardy, John, Shulman, Lisa M., Jankovic, Joseph, Shulman, Joshua M., Heutink, Peter, Gasser, Thomas, Cannon, Paul, Scholz, Sonja W., Morris, Huw, Cookson, Mark R., Nalls, Mike A., Gan-Or, Ziv, Singleton, Andrew B.

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Blood Leukocyte DNA Methylation Predicts Risk of Future Myocardial Infarction and Coronary Heart Disease von Agha, Golareh, Mendelson, Michael M, Ward-Caviness, Cavin K, Joehanes, Roby, Huan, TianXiao, Gondalia, Rahul, Salfati, Elias, Brody, Jennifer A, Fiorito, Giovanni, Bressler, Jan, Chen, Brian H, Ligthart, Symen, Guarrera, Simonetta, Colicino, Elena, Just, Allan C, Wahl, Simone, Gieger, Christian, Vandiver, Amy R, Tanaka, Toshiko, Hernandez, Dena G, Pilling, Luke C, Singleton, Andrew B, Sacerdote, Carlotta, Krogh, Vittorio, Panico, Salvatore, Tumino, Rosario, Li, Yun, Zhang, Guosheng, Stewart, James D, Floyd, James S, Wiggins, Kerri L, Rotter, Jerome I, Multhaup, Michael, Bakulski, Kelly, Horvath, Steven, Tsao, Philip S, Absher, Devin M, Vokonas, Pantel, Hirschhorn, Joel, Fallin, M Daniele, Liu, Chunyu, Bandinelli, Stefania, Boerwinkle, Eric, Dehghan, Abbas, Schwartz, Joel D, Psaty, Bruce M, Feinberg, Andrew P, Hou, Lifang, Ferrucci, Luigi, Sotoodehnia, Nona, Matullo, Giuseppe, Peters, Annette, Fornage, Myriam, Assimes, Themistocles L, Whitsel, Eric A, Levy, Daniel, Baccarelli, Andrea A

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Blood Leukocyte DNA Methylation Predicts Risk of Future Myocardial Infarction and Coronary Heart Disease: A Longitudinal Study of 11 461 Participants From Population-Based Cohorts von Agha, Golareh, Mendelson, Michael M, Ward-Caviness, Cavin K, Joehanes, Roby, Huan, TianXiao, Gondalia, Rahul, Salfati, Elias, Brody, Jennifer A, Fiorito, Giovanni, Bressler, Jan, Chen, Brian H, Ligthart, Symen, Guarrera, Simonetta, Colicino, Elena, Just, Allan C, Wahl, Simone, Gieger, Christian, Vandiver, Amy R, Tanaka, Toshiko, Hernandez, Dena G, Pilling, Luke C, Singleton, Andrew B, Sacerdote, Carlotta, Krogh, Vittorio, Panico, Salvatore, Tumino, Rosario, Li, Yun, Zhang, Guosheng, Stewart, James D, Floyd, James S, Wiggins, Kerri L, Rotter, Jerome I, Multhaup, Michael, Bakulski, Kelly, Horvath, Steven, Tsao, Philip S, Absher, Devin M, Vokonas, Pantel, Hirschhorn, Joel, Fallin, M Daniele, Liu, Chunyu, Bandinelli, Stefania, Boerwinkle, Eric, Dehghan, Abbas, Schwartz, Joel D, Psaty, Bruce M, Feinberg, Andrew P, Hou, Lifang, Ferrucci, Luigi, Sotoodehnia, Nona, Matullo, Giuseppe, Peters, Annette, Fornage, Myriam, Assimes, Themistocles L, Whitsel, Eric A, Levy, Daniel, Baccarelli, Andrea A

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Race-specific alterations in DNA methylation among middle-aged African Americans and Whites with metabolic syndrome von Chitrala, Kumaraswamy Naidu, Hernandez, Dena G., Nalls, Michael A., Mode, Nicolle A., Zonderman, Alan B., Ezike, Ngozi, Evans, Michele K.

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MAPT expression and splicing is differentially regulated by brain region: relation to genotype and implication for tauopathies von TRABZUNI, Daniah, WRAY, Selina, AREPALLI, Sampath, SINGLETON, Andrew B, COOKSON, Mark R, PITTMAN, Alan M, DE SILVA, Rohan, WEALE, Michael E, HARDY, John, RYTEN, Mina, VANDROVCOVA, Jana, RAMASAMY, Adaikalavan, WALKER, Robert, SMITH, Colin, LUK, Connie, RAPHAEL GIBBS, J, DILLMAN, Allissa, HERNANDEZ, Dena G

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APOE gene region methylation is associated with cognitive performance in middle-aged urban adults von Shen, Botong, Hernandez, Dena G., Chitrala, Kumaraswamy Naidu, Fanelli-Kuczmarski, Marie T., Noren Hooten, Nicole, Pacheco, Natasha L., Mode, Nicolle A., Zonderman, Alan B., Ezike, Ngozi, Evans, Michele K.

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Imputation of variants from the 1000 Genomes Project modestly improves known associations and can identify low-frequency variant-phenotype associations undetected by HapMap based i... von Wood, Andrew R, Perry, John R B, Tanaka, Toshiko, Hernandez, Dena G, Zheng, Hou-Feng, Melzer, David, Gibbs, J Raphael, Nalls, Michael A, Weedon, Michael N, Spector, Tim D, Richards, J Brent, Bandinelli, Stefania, Ferrucci, Luigi, Singleton, Andrew B, Frayling, Timothy M

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Distinct DNA methylation changes highly correlated with chronological age in the human brain von HERNANDEZ, Dena G, NALLS, Michael A, SINGLETON, Andrew B, RAPHAEL GIBBS, J, AREPALLI, Sampath, VAN DER BRUG, Marcel, CHONG, Sean, MOORE, Matthew, LONGO, Dan L, COOKSON, Mark R, TRAYNOR, Bryan J

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Accelerating Medicines Partnership: Parkinson's Disease. Genetic Resource von Iwaki, Hirotaka, Leonard, Hampton L., Makarious, Mary B., Bookman, Matt, Landin, Barry, Vismer, David, Casey, Bradford, Gibbs, J. Raphael, Hernandez, Dena G., Blauwendraat, Cornelis, Vitale, Daniel, Song, Yeajin, Kumar, Dinesh, Dalgard, Clifton L., Sadeghi, Mahdiar, Dong, Xianjun, Misquitta, Leonie, Scholz, Sonja W., Scherzer, Clemens R., Nalls, Mike A., Biswas, Shameek, Singleton, Andrew B.

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Heterozygous PRKN mutations are common but do not increase the risk of Parkinson's disease von Zhu, William, Huang, Xiaoping, Yoon, Esther, Bandres-Ciga, Sara, Blauwendraat, Cornelis, Billingsley, Kimberly J, Cade, Joshua H, Wu, Beverly P, Williams, Victoria H, Schindler, Alice B, Brooks, Janet, Gibbs, J Raphael, Hernandez, Dena G, Ehrlich, Debra, Singleton, Andrew B, Narendra, Derek P

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Mutations in GBA2 Cause Autosomal-Recessive Cerebellar Ataxia with Spasticity von Hammer, Monia B., Eleuch-Fayache, Ghada, Schottlaender, Lucia V., Nehdi, Houda, Gibbs, J. Raphael, Arepalli, Sampath K., Chong, Sean B., Hernandez, Dena G., Sailer, Anna, Liu, Guoxiang, Mistry, Pramod K., Cai, Huaibin, Shrader, Ginamarie, Sassi, Celeste, Bouhlal, Yosr, Houlden, Henry, Hentati, Fayçal, Amouri, Rim, Singleton, Andrew B.

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Genomic Variation in Seven Khoe-San Groups Reveals Adaptation and Complex African History von Schlebusch, Carina M., Skoglund, Pontus, Sjödin, Per, Gattepaille, Lucie M., Hernandez, Dena, Jay, Flora, Li, Sen, De Jongh, Michael, Singleton, Andrew, Blum, Michael G. B., Soodyall, Himla, Jakobsson, Mattias

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Genome-wide association study reveals genetic risk underlying Parkinson's disease von Singleton, Andrew B, Gasser, Thomas, Simón-Sánchez, Javier, Schulte, Claudia, Bras, Jose M, Sharma, Manu, Gibbs, J Raphael, Berg, Daniela, Paisan-Ruiz, Coro, Lichtner, Peter, Scholz, Sonja W, Hernandez, Dena G, Krüger, Rejko, Federoff, Monica, Klein, Christine, Goate, Alison, Perlmutter, Joel, Bonin, Michael, Nalls, Michael A, Illig, Thomas, Gieger, Christian, Houlden, Henry, Steffens, Michael, Okun, Michael S, Racette, Brad A, Cookson, Mark R, Foote, Kelly D, Fernandez, Hubert H, Traynor, Bryan J, Schreiber, Stefan, Arepalli, Sampath, Zonozi, Ryan, Gwinn, Katrina, van der Brug, Marcel, Lopez, Grisel, Chanock, Stephen J, Schatzkin, Arthur, Park, Yikyung, Hollenbeck, Albert, Gao, Jianjun, Huang, Xuemei, Wood, Nick W, Lorenz, Delia, Deuschl, Günther, Chen, Honglei, Riess, Olaf, Hardy, John A

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