Exploring Bioinformatics Solutions for Improved Leishmaniasis Diagnostic Tools: A Review von Capistrano Costa, Natáli T, de Souza Pereira, Allana M, Silva, Cibele C, Souza, Emanuelle de Oliveira, de Oliveira, Beatriz C, Ferreira, Luiz Felipe G R, Hernandes, Marcelo Z, Pereira, Valéria R A

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Discovery of Phthalimides as Immunomodulatory and Antitumor Drug Prototypes von Pessoa, Claudia, Ferreira, Paulo Michel P., Lotufo, Letícia Veras C., de Moraes, Manoel O., Cavalcanti, Suellen M. T., Coêlho, Lucas Cunha D., Hernandes, Marcelo Z., Leite, Ana Cristina L., De Simone, Carlos A., Costa, Vlaudia M. A., Souza, Valdênia M. O.

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New PPARγ partial agonist improves obesity-induced metabolic alterations and atherosclerosis in LDLr−/− mice von Silva, Jacqueline C., César, Fernanda A., de Oliveira, Edson M., Turato, Walter M., Tripodi, Gustavo L., Castilho, Gabriela, Machado-Lima, Adriana, de las Heras, Beatriz, Boscá, Lisardo, Rabello, Marcelo M., Hernandes, Marcelo Z., Pitta, Marina G.R., Pitta, Ivan R., Passarelli, Marisa, Rudnicki, Martina, Abdalla, Dulcineia S.P.

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Supramolecular interactions between β‐lapachone with cyclodextrins studied using isothermal titration calorimetry and molecular modeling von Xavier‐Junior, Francisco H., Rabello, Marcelo M., Hernandes, Marcelo Z., Dias, Marília E.S., Andrada, Otoni H.M.S., Bezerra, Beatriz P., Ayala, Alejandro P., Santos‐Magalhães, Nereide S.

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Molecular modeling and cytotoxicity of diffractaic acid: HP-β-CD inclusion complex encapsulated in microspheres von Silva, Camilla V.N.S., Barbosa, Jéssica A.P., Ferraz, Milena S., Silva, Nicácio H., Honda, Neli K., Rabello, Marcelo M., Hernandes, Marcelo Z., Bezerra, Beatriz P., Cavalcanti, Isabella M.F., Ayala, Alejandro P., Santos, Noemia P.S., Santos-Magalhães, Nereide S.

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The encapsulation of β-lapachone in 2-hydroxypropyl-β-cyclodextrin inclusion complex into liposomes: A physicochemical evaluation and molecular modeling approach von Cavalcanti, Isabella M.F., Mendonça, Elisângela A.M., Lira, Mariane C.B., Honrato, Sara B., Camara, Celso A., Amorim, Rosa V.S., Filho, Josué Mendes, Rabello, Marcelo M., Hernandes, Marcelo Z., Ayala, Alejandro P., Santos-Magalhães, Nereide S.

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The Use of Solid Dispersion Systems in Hydrophilic Carriers to Increase Benznidazole Solubility von Lima, Ádley A.N., Soares-Sobrinho, José L., Silva, Jeckson L., Corrêa-Júnior, Roberto A.C., Lyra, Magaly A.M., Santos, Fabiana L.A., Oliveira, Boaz G., Hernandes, Marcelo Z., Rolim, Larissa A., Rolim-Neto, Pedro J.

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Chemical synthesis, docking studies and biological effects of a pan peroxisome proliferator-activated receptor agonist and cyclooxygenase inhibitor von Santin, José Roberto, Uchôa, Flávia D.T., Lima, Maria do Carmo A., Rabello, Marcelo M., Machado, Isabel Daufenback, Hernandes, Marcelo Z., Amato, Angelica A., Milton, Flora Aparecida, Webb, Paul, Neves, Francisco de Assis Rocha, Galdino, Suely L., Pitta, Ivan Rocha, Farsky, Sandra H.P.

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Isolation, homology modeling and renal effects of a C-type natriuretic peptide from the venom of the Brazilian yellow scorpion (Tityus serrulatus) von Alves, Renata S., Ximenes, Rafael M., Jorge, Antonio R.C., Nascimento, Nilberto R.F., Martins, René D., Rabello, Marcelo M., Hernandes, Marcelo Z., Toyama, Daniela O., Toyama, Marcos H., Martins, Alice M.C., Havt, Alexandre, Monteiro, Helena S.A.

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Interaction of Morphine With a New α2 -Adrenoceptor Agonist in Mice von Sudo, Roberto T, Calasans-Maia, Jorge A, Galdino, Suely L, Lima, Maria C.A, Zapata-Sudo, Gisele, Hernandes, Marcelo Z, Pitta, Ivan R

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A theoretical study of red-shifting and blue-shifting hydrogen bonds occurring between imidazolidine derivatives and PEG/PVP polymers von Oliveira, Boaz G., Lima, Maria C. A., Pitta, Ivan R., Galdino, Suely L., Hernandes, Marcelo Z.

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Enhanced Antiproliferative Activity of the New Anticancer Candidate LPSF/AC04 in Cyclodextrin Inclusion Complexes Encapsulated into Liposomes von Mendonça, Elisângela A. M., Lira, Mariane C. B., Rabello, Marcelo M., Cavalcanti, Isabella M. F., Galdino, Suely L., Pitta, Ivan R., do Carmo A. Lima, Maria, Pitta, Maira G. R., Hernandes, Marcelo Z., Santos-Magalhães, Nereide S.

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Solid Dispersions of Imidazolidinedione by PEG and PVP Polymers with Potential Antischistosomal Activities von Guedes, Francimary L., de Oliveira, Boaz G., Hernandes, Marcelo Z., De Simone, Carlos A., Veiga, Francisco J. B., de Lima, Maria do Carmo A., Pitta, Ivan R., Galdino, Suely L., Neto, Pedro José Rolim

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Inhibition of Neurotoxic Secretory Phospholipases A2 Enzymatic, Edematogenic, and Myotoxic Activities by Harpalycin 2, an Isoflavone Isolated from Harpalyce brasiliana Benth von Gaeta, Henrique Hessel, Hernandes, Marcelo Z., Monteiro, Helena S. A., Toyama, Marcos H., Soares, Veronica C. G., Buzzo, Simone C., Diz-Filho, Eduardo B. S., Fagundes, Fábio H. R., Silveira, Edilberto R., Araújo, Renata M., Rabello, Marcelo M., Ximenes, Rafael Matos, Toyama, Daniela de O.

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Harpalycin 2 inhibits the enzymatic and platelet aggregation activities of PrTX-III, a D49 phospholipase A2 from Bothrops pirajai venom von Ximenes, Rafael M, Alves, Renata S, Pereira, Ticiana P, Araújo, Renata M, Silveira, Edilberto R, Rabello, Marcelo M, Hernandes, Marcelo Z, Soares, Veronica C G, Bristot, Daniel, Pires, Camila L, Toyama, Daniela O, Gaeta, Henrique H, Monteiro, Helena S A, Toyama, Marcos H

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Rotational features of carbon-nitrogen bonds in axially chiral o- tert-butyl anilides and related molecules. Potential substrates for the ‘prochiral auxiliary’ approach to asymmetr... von Curran, Dennis P., Hale, Gregory R., Geib, Steven J., Balog, Aaron, Cass, Quezia B., Degani, Ana Luiza G., Hernandes, Marcelo Z., Freitas, Luiz Carlos G.

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Comparative structural analysis of anhydrous and monohydrated polymorphs of diclofenac diethylammonium: Implications for stability, dissolution, and bioavailability von Sallum, Lóide O., Siqueira, Waléria N., Aguiar, Antônio S.N., Duarte, Vitor S., Sales, Samuel B.S., Lobo, Géssika, Hernandes, Marcelo Z., Camargo, Ademir. J., Napolitano, Hamilton B.

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AIPAR: ab initio parametrization of intermolecular potentials for computer simulations von Hernandes, Marcelo Z, Longo, Ricardo L

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Inside Cover: Discovery of Phthalimides as Immunomodulatory and Antitumor Drug Prototypes (ChemMedChem 4/2010) von Pessoa, Claudia, Ferreira, Paulo Michel P., Lotufo, Letícia Veras C., de Moraes, Manoel O., Cavalcanti, Suellen M. T., Coêlho, Lucas Cunha D., Hernandes, Marcelo Z., Leite, Ana Cristina L., De Simone, Carlos A., Costa, Vlaudia M. A., Souza, Valdênia M. O.

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Novel Nitrofurazone Derivatives Endowed with Antimicrobial Activity von Brondani, Dalci J., Caetano, Nelly, de M. Moreira, Diogo R., Soares, Rogério R., Lima, Vânia T., de Araújo, Janete M., de Abreu, Fabiane C., de Oliveira, Boaz G., Hernandes, Marcelo Z., Leite, Ana C. L.

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