TNAP upregulation is a critical factor in Tauopathies and its blockade ameliorates neurotoxicity and increases life-expectancy von Sebastián-Serrano, Álvaro, Merchán-Rubira, Jesús, Di Lauro, Caterina, Bianchi, Carolina, Soria-Tobar, Lucía, Narisawa, Sonoko, Millán, José L., Ávila, Jesús, Hernández, Félix, Díaz-Hernández, Miguel

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Altered P2X7-receptor level and function in mouse models of Huntington's disease and therapeutic efficacy of antagonist administration von Díaz-Hernández, Miguel, Díez-Zaera, María, Sánchez-Nogueiro, Jesús, Gómez-Villafuertes, Rosa, Canals, Josep M, Alberch, Jordi, Miras-Portugal, María Teresa, Lucas, José J

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Adenylate cyclase 5 coordinates the action of ADP, P2Y1, P2Y13 and ATP-gated P2X7 receptors on axonal elongation von del Puerto, Ana, Díaz-Hernández, Juan-Ignacio, Tapia, Mónica, Gomez-Villafuertes, Rosa, Benitez, María José, Zhang, Jin, Miras-Portugal, María Teresa, Wandosell, Francisco, Díaz-Hernández, Miguel, Garrido, Juan José

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Acute Polyglutamine Expression in Inducible Mouse Model Unravels Ubiquitin/Proteasome System Impairment and Permanent Recovery Attributable to Aggregate Formation von Ortega, Zaira, Diaz-Hernandez, Miguel, Maynard, Christa J, Hernandez, Felix, Dantuma, Nico P, Lucas, Jose J

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The Specificity Protein Factor Sp1 Mediates Transcriptional Regulation of P2X7 Receptors in the Nervous System von García-Huerta, Paula, Díaz-Hernandez, Miguel, Delicado, Esmerilda G., Pimentel-Santillana, María, Miras-Portugal, Mª Teresa, Gómez-Villafuertes, Rosa

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Reduced expression of the TrkB receptor in Huntington's disease mouse models and in human brain von Ginés, Silvia, Bosch, Miquel, Marco, Sonia, Gavaldà, Núria, Díaz-Hernández, Miguel, Lucas, José J., Canals, Josep M., Alberch, Jordi

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Neuronal Induction of the Immunoproteasome in Huntington's Disease von Diaz-Hernandez, Miguel, Hernandez, Felix, Martin-Aparicio, Ester, Gomez-Ramos, Pilar, Moran, Maria A, Castano, Jose G, Ferrer, Isidro, Avila, Jesus, Lucas, Jose J

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Accumulation of Ubiquitin Conjugates in a Polyglutamine Disease Model Occurs without Global Ubiquitin/Proteasome System Impairment von Maynard, Christa J., Böttcher, Claudia, Ortega, Zaira, Smith, Ruben, Florea, Bogdan I., Díaz-Hernández, Miguel, Brundin, Patrik, Overkleeft, Hermen S., Li, Jia-Yi, Lucas, Jose J., Dantuma, Nico P., Zoghbi, Huda Y.

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Inhibition of 26S proteasome activity by huntingtin filaments but not inclusion bodies isolated from mouse and human brain von Díaz‐Hernández, Miguel, Valera, Adriana G., Morán, María A., Gómez‐Ramos, Pilar, Alvarez‐Castelao, Beatriz, Castaño, José G., Hernández, Félix, Lucas, José J.

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The Neurotoxic Role of Extracellular Tau Protein von Sebastián-Serrano, Álvaro, de Diego-García, Laura, Díaz-Hernández, Miguel

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Reduced calcineurin protein levels and activity in exon-1 mouse models of Huntington's disease: Role in excitotoxicity von Xifró, Xavier, Giralt, Albert, Saavedra, Ana, García-Martínez, Juan M, Díaz-Hernández, Miguel, Lucas, José J, Alberch, Jordi, Pérez-Navarro, Esther

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Amyloid Peptide Induced Neuroinflammation Increases the P2X7 Receptor Expression in Microglial Cells, Impacting on Its Functionality von Martínez-Frailes, Carlos, Di Lauro, Caterina, Bianchi, Carolina, de Diego-García, Laura, Sebastián-Serrano, Álvaro, Boscá, Lisardo, Díaz-Hernández, Miguel

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The Role of P2X7 Receptor in Alzheimer’s Disease von Francistiová, Linda, Bianchi, Carolina, Di Lauro, Caterina, Sebastián-Serrano, Álvaro, de Diego-García, Laura, Kobolák, Julianna, Dinnyés, András, Díaz-Hernández, Miguel

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Peripheral nervous system effects in the PS19 tau transgenic mouse model of tauopathy von Merchán-Rubira, Jesús, Sebastián-Serrano, Álvaro, Díaz-Hernández, Miguel, Avila, Jesús, Hernández, Félix

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Extracellular tau is toxic to neuronal cells von Gómez-Ramos, Alberto, Díaz-Hernández, Miguel, Cuadros, Raquel, Hernández, Félix, Avila, Jesús

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Seizure suppression and neuroprotection by targeting the purinergic P2X7 receptor during status epilepticus in mice von Engel, Tobias, Gomez‐Villafuertes, Rosa, Tanaka, Katsuhiro, Mesuret, Guillaume, Sanz‐Rodriguez, Amaya, Garcia‐Huerta, Paula, Miras‐Portugal, M. Teresa, Henshall, David C., Diaz‐Hernandez, Miguel

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Increased neocortical expression of the P2X7 receptor after status epilepticus and anticonvulsant effect of P2X7 receptor antagonist A‐438079 von Jimenez‐Pacheco, Alba, Mesuret, Guillaume, Sanz‐Rodriguez, Amaya, Tanaka, Katsuhiro, Mooney, Claire, Conroy, Ronan, Miras‐Portugal, Maria Teresa, Diaz‐Hernandez, Miguel, Henshall, David C., Engel, Tobias

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Neurodevelopmental alterations and seizures developed by mouse model of infantile hypophosphatasia are associated with purinergic signalling deregulation von Sebastián-Serrano, Álvaro, Engel, Tobias, de Diego-García, Laura, Olivos-Oré, Luis A, Arribas-Blázquez, Marina, Martínez-Frailes, Carlos, Pérez-Díaz, Carmen, Millán, José Luis, Artalejo, Antonio R, Miras-Portugal, María Teresa, Henshall, David C, Díaz-Hernández, Miguel

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Editorial: Protein Degradation, Aggregation, Membrane Trafficking and Exosomes in Neuronal Health and Disease von Campbell, Douglas S., Díaz-Hernández, Miguel, Alvarez-Castelao, Beatriz

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Inhibition of the ATP-gated P2X7 receptor promotes axonal growth and branching in cultured hippocampal neurons von Díaz-Hernandez, Miguel, del Puerto, Ana, Díaz-Hernandez, Juan Ignacio, Diez-Zaera, María, Lucas, José Javier, Garrido, Juan José, Miras-Portugal, María Teresa

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