The Rac inhibitor HV-107 as a potential therapeutic for metastatic breast cancer von Crespo, Grace Velez, Ortiz, Jescelica, O'Farrill, Eliud Hernández, Vlaar, Cornelis P, Inyushin, Mikhail, Kucheryavykh, Yuriy, Kucheryavykh, Lilia

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Targeting Lipocalin-2 in Inflammatory Breast Cancer Cells with Small Interference RNA and Small Molecule Inhibitors von Santiago-Sánchez, Ginette S, Noriega-Rivera, Ricardo, Hernández-O'Farrill, Eliud, Valiyeva, Fatma, Quiñones-Diaz, Blanca, Villodre, Emilly S, Debeb, Bisrat G, Rosado-Albacarys, Andrea, Vivas-Mejía, Pablo E

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Efficacy of Rac and Cdc42 Inhibitor MBQ-167 in Triple-negative Breast Cancer von Cruz-Collazo, Ailed, Ruiz-Calderon, Jean F, Picon, Hector, Borrero-Garcia, Luis D, Lopez, Irmaris, Castillo-Pichardo, Linette, Del Mar Maldonado, Maria, Duconge, Jorge, Medina, Julia I, Bayro, Marvin J, Hernández-O'Farrill, Eliud, Vlaar, Cornelis P, Dharmawardhane, Suranganie

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Design, synthesis and biological evaluation of new carbazole derivatives as anti-cancer and anti-migratory agents von Vlaar, Cornelis P., Castillo-Pichardo, Linette, Medina, Julia I., Marrero-Serra, Cathyria M., Vélez, Ericka, Ramos, Zulma, Hernández, Eliud

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Low-frequency variants at the CYP2C9 locus among Puerto Rican patients on warfarin: in silico predictions of functionality and conservation von Claudio-Campos, Karla, Moneró-Paredes, Mariangeli, Hernández, Eliud, Renta, Jessicca, Duconge, Jorge

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Synthesis of 1,4-dihydro-benzo[ d][1,3]oxazin-2-ones from phthalides via an aminolysis-Hofmann rearrangement protocol von Hernández, Eliud, Vélez, Jessica M., Vlaar, Cornelis P.

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Characterization of EHop-016, Novel Small Molecule Inhibitor of Rac GTPase von Montalvo-Ortiz, Brenda L., Castillo-Pichardo, Linette, Hernández, Eliud, Humphries-Bickley, Tessa, De La Mota-Peynado, Alina, Cubano, Luis A., Vlaar, Cornelis P., Dharmawardhane, Suranganie

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Characterization of a Dual Rac/Cdc42 Inhibitor MBQ-167 in Metastatic Cancer von Humphries-Bickley, Tessa, Castillo-Pichardo, Linette, Hernandez-O'Farrill, Eliud, Borrero-Garcia, Luis D, Forestier-Roman, Ingrid, Gerena, Yamil, Blanco, Manuel, Rivera-Robles, Michael J, Rodriguez-Medina, José R, Cubano, Luis A, Vlaar, Cornelis P, Dharmawardhane, Suranganie

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Synthesis, Anti-Cancer and Anti-Migratory Evaluation of 3,6-Dibromocarbazole and 5-Bromoindole Derivatives von Butler-Fernández, Krystal M, Ramos, Zulma, Francis-Malavé, Adela M, Bloom, Joseph, Dharmawardhane, Suranganie, Hernández, Eliud

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Characterization of Rac/Cdc42 Inhibitors as Anti‐cancer Compounds von Medina, Julia, Hernández, Eliud, Vlaar, Cornelis, Dharmawardhane, Suranganie

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Pharmacokinetics of the Rac/Cdc42 Inhibitor MBQ-167 in Mice by Supercritical Fluid Chromatography–Tandem Mass Spectrometry von Maldonado, María del Mar, Rosado-González, Gabriela, Bloom, Joseph, Duconge, Jorge, Ruiz-Calderón, Jean F, Hernández-O’Farrill, Eliud, Vlaar, Cornelis, Rodríguez-Orengo, José F, Dharmawardhane, Suranganie

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Efficacy and delivery strategies of the dual Rac/Cdc42 inhibitor MBQ-167 in HER2 overexpressing breast cancer von Velázquez-Vega, Luis E., Rivera-Robles, Michael, Sánchez-Álvarez, Annelis O., Vivas-Mejía, Pablo E., Aponte-Reyes, Miciely, Cruz-Collazo, Ailed M., Grafals-Ruiz, Nilmary, Dorta-Estremera, Stephanie, Hernández-O'Farrill, Eliud, Vlaar, Cornelis P, Dharmawardhane, Suranganie

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Novel inhibitors of Rac1 in metastatic breast cancer von Hernández, Eliud, De La Mota-Peynado, Alina, Dharmawardhane, Surangani, Vlaar, Cornelis P

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Pharmacokinetics of Rac inhibitor EHop-016 in mice by ultra-performance liquid chromatography tandem mass spectrometry von Humphries-Bickley, Tessa, Castillo-Pichardo, Linette, Corujo-Carro, Francheska, Duconge, Jorge, Hernandez-O’Farrill, Eliud, Vlaar, Cornelis, Rodriguez-Orengo, Jose F., Cubano, Luis, Dharmawardhane, Suranganie

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Abstract 347: Comparative activity of MBQ-167 metabolites in metastatic breast cancer von Medina, Julia I., Hernández, Eliud, Vlaar, Cornelis, Dharmawardhane, Suranganie

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Simalikalactone D, a Potential Anticancer Compound from Simarouba tulae , an Endemic Plant of Puerto Rico von Mendez, Belmari, Reyes, Jeyshka, Conde, Isabel, Ramos, Zulma, Lozada, Eunice, Cruz, Ailed M, Asencio, Gabriela, Carvajal, Augusto, Dharmawardhane, Suranganie, Piñero-Cruz, Dalice M, Hernández, Eliud, Vivas, Pablo, Ospina, Claudia A

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Abstract 4185: The novel Rac inhibitor HV-107 as a potential therapeutic for metastatic breast cancer von Crespo, Grace E. Velez, Hernández, Eliud, Vlaar, Cornelis, Dharmawardhane, Suranganie, Castillo-Pichardo, Linette

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The Rac Inhibitor EHop-016 Inhibits Mammary Tumor Growth and Metastasis in a Nude Mouse Model von Castillo-Pichardo, Linette, Humphries-Bickley, Tessa, De La Parra, Columba, Forestier-Roman, Ingrid, Martinez-Ferrer, Magaly, Hernandez, Eliud, Vlaar, Cornelis, Ferrer-Acosta, Yancy, Washington, Anthony V, Cubano, Luis A, Rodriguez-Orengo, Jose, Dharmawardhane, Suranganie

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Novel Rac Inhibitors as Targeted Therapeutics for Metastatic Breast Cancer von Asencio‐Torres, Gabriela, Hernández, Eliud, Vlaar, Cornelis, Dharmawardhane, Suranganie, Castillo‐Pichardo, Linette

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Abstract 181: Discovery of novel targeted therapeutics for metastatic breast cancer von Valle, Cristina Del, Hernández, Eliud, Vlaar, Cornelis P., Cubano, Luis A., Dharmawardhane, Suranganie, Castillo-Pichardo, Linette

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