Combination of Pantothenamides with Vanin Inhibitors as a Novel Antibiotic Strategy against Gram-Positive Bacteria von JANSEN, Patrick A. M, HERMKENS, Pedro H. H, ZEEUWEN, Patrick L. J. M, BOTMAN, Peter N. M, BLAAUW, Richard H, BURGHOUT, Peter, VAN GALEN, Peter M, MOUTON, Johan W, RUTJES, Floris P. J. T, SCHALKWIJK, Joost

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Stable pantothenamide bioisosteres: novel antibiotics for Gram-positive bacteria von Jansen, Patrick A. M., van der Krieken, Danique A., Botman, Peter N. M., Blaauw, Richard H., Cavina, Lorenzo, Raaijmakers, Eline M., de Heuvel, Erik, Sandrock, Julia, Pennings, Lian J., Hermkens, Pedro H. H., Zeeuwen, Patrick L. J. M., Rutjes, Floris P. J. T., Schalkwijk, Joost

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Discovery of Small Molecule Vanin Inhibitors: New Tools To Study Metabolism and Disease von Jansen, Patrick A. M, van Diepen, Janna A, Ritzen, Bas, Zeeuwen, Patrick L. J. M, Cacciatore, Ivana, Cornacchia, Catia, van Vlijmen-Willems, Ivonne M. J. J, de Heuvel, Erik, Botman, Peter N. M, Blaauw, Richard H, Hermkens, Pedro H. H, Rutjes, Floris P. J. T, Schalkwijk, Joost

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SAR study of 2,3,4,14b-tetrahydro-1H-dibenzo[b,f]pyrido[1,2-d][1,4]oxazepines as progesterone receptor agonists von Dols, Paul P M A, Folmer, Brigitte J B, Hamersma, Hans, Kuil, Cor W, Lucas, Hans, Ollero, Lourdes, Rewinkel, Jos B M, Hermkens, Pedro H H

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Novel pantothenate derivatives for anti-malarial chemotherapy von Pett, Helmi E, Jansen, Patrick A M, Hermkens, Pedro H H, Botman, Peter N M, Beuckens-Schortinghuis, Christien A, Blaauw, Richard H, Graumans, Wouter, van de Vegte-Bolmer, Marga, Koolen, Karin M J, Rutjes, Floris P J T, Dechering, Koen J, Sauerwein, Robert W, Schalkwijk, Joost

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Catalyst Recycling via Hydrogen-Bonding-Based Affinity Tags von Gruijters, Bas W. T, Broeren, Maarten A. C, van Delft, Floris L, Sijbesma, Rint P, Hermkens, Pedro H. H, Rutjes, Floris P. J. T

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Synthesis of dihydrouracils spiro-fused to pyrrolidines: druglike molecules based on the 2-arylethyl amine scaffold von Blanco-Ania, Daniel, Valderas-Cortina, Carolina, Hermkens, Pedro H H, Sliedregt, Leo A J M, Scheeren, Hans W, Rutjes, Floris P J T

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Synthesis of cucurbitine derivatives: facile straightforward approach to methyl 3-amino-4-aryl-1-methylpyrrolydine-3-carboxylates von Blanco-Ania, Daniel, Hermkens, Pedro H.H., Sliedregt, Leo A.J.M., Scheeren, Hans W., Rutjes, Floris P.J.T.

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Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183 von de Vries, Laura E., Jansen, Patrick A. M., Barcelo, Catalina, Munro, Justin, Verhoef, Julie M. J., Pasaje, Charisse Flerida A., Rubiano, Kelly, Striepen, Josefine, Abla, Nada, Berning, Luuk, Bolscher, Judith M., Demarta-Gatsi, Claudia, Henderson, Rob W. M., Huijs, Tonnie, Koolen, Karin M. J., Tumwebaze, Patrick K., Yeo, Tomas, Aguiar, Anna C. C., Angulo-Barturen, Iñigo, Churchyard, Alisje, Baum, Jake, Fernández, Benigno Crespo, Fuchs, Aline, Gamo, Francisco-Javier, Guido, Rafael V. C., Jiménez-Diaz, María Belén, Pereira, Dhelio B., Rochford, Rosemary, Roesch, Camille, Sanz, Laura M., Trevitt, Graham, Witkowski, Benoit, Wittlin, Sergio, Cooper, Roland A., Rosenthal, Philip J., Sauerwein, Robert W., Schalkwijk, Joost, Hermkens, Pedro H. H., Bonnert, Roger V., Campo, Brice, Fidock, David A., Llinás, Manuel, Niles, Jacquin C., Kooij, Taco W. A., Dechering, Koen J.

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Stereoselective synthesis of verruculogen TR-2 featuring the mild formation of a dihydro-.beta.-carboline as an intermediate von Hermkens, Pedro H. H, Plate, Ralf, Kruse, Chris G, Scheeren, Hans W, Ottenheijm, Harry C. J

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Backbone Amide Linker Strategy for the Synthesis of 1,4-Triazole-Containing Cyclic Tetra- and Pentapeptides von Springer, Jasper, de Cuba, Kimberly R., Calvet-Vitale, Sandrine, Geenevasen, Jan A. J., Hermkens, Pedro H. H., Hiemstra, Henk, van Maarseveen, Jan H.

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Antiviral and antitumor structure-activity relationship studies on tetracyclic eudistomines von Van Maarseveen, Jan H, Hermkens, Pedro H. H, De Clercq, Erik, Balzarini, Jan, Scheeren, Hans W, Kruse, Chris G

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Solid Phase Synthesis von Brown, Angus R., Hermkens, Pedro H. H., Ottenheijm, Harry C. J., Rees, David C.

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A Novel Purification Method in Organic Synthesis Using Hydrogen Bonding von Gruijters, Bas W. T., Verkade, Jorge M. M., van Delft, Floris L., Sijbesma, Rint P., Hermkens, Pedro H. H., Rutjes, Floris P. J. T.

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Employment of nitriles in the stereoselective cycloaddition to nitrones von Plate, Ralf, Hermkens, Pedro H. H, Smits, Jan M. M, Nivard, Rutger J. F, Ottenheijm, Harry C. J

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Development and application of allyl, 2-sulfonylethyl and 2-thioethyl carbamate linkers for solid phase N-acyliminium ion chemistry von van Maarseveen, Jan H., Meester, Wim J. N., Veerman, Johan J. N., Kruse, Chris G., Hermkens, Pedro H. H., Rutjes, Floris P. J. T., Hiemstra, Henk

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SAR study of 2,3,4,14b-tetrahydro-1Η-dibenzo[b,f]pyrido-[1,2-d][1,4]oxazepines as progesterone receptor agonists von DOLS, Paul P. M. A, FOLMER, Brigitte J. B, HAMERSMA, Hans, KUIL, Cor W, LUCAS, Hans, OLLERO, Lourdes, REWINKEL, Jos B. M, HERMKENS, Pedro H. H

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Nitrone cycloaddition in the stereoselective synthesis of .beta.-carbolines from N-hydroxytryptophan von Plate, Ralf, Hermkens, Pedro H. H, Smits, Jan M. M, Ottenheijm, Harry C. J

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Application of an isoxazolidine in a stereoselective approach to the fumitremorgin series von Plate, Ralf, Hermkens, Pedro H. H, Behm, Helmut, Ottenheijm, Harry C. J

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Intramolecular Pictet-Spengler reaction of N-alkoxytryptophans and tryptamines. 2. Synthesis of Corynanthe alkaloid derivatives containing a tetrahydro-1,2-oxazine as the D ring von Hermkens, Pedro H. H, Van Maarseveen, Jan H, Berens, Harry W, Smits, Jan M. M, Kruse, Chris G, Scheeren, Hans W

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