Halichondrin B and homohalichondrin B, marine natural products binding in the vinca domain of tubulin. Discovery of tubulin-based mechanism of action by analysis of differential cy... von BAI, R, PAULL, K. D, HERALD, C. L, MALSPEIS, L, PETTIT, G. R, HAMEL, E

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Spongistatin 1, a highly cytotoxic, sponge-derived, marine natural product that inhibits mitosis, microtubule assembly, and the binding of vinblastine to tubulin von BAI, R, CICHACZ, Z. A, HERALD, C. L, PETTIT, G. R, HAMEL, E

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Modeling of the Bryostatins to the Phorbol Ester Pharmacophore on Protein Kinase C von Wender, Paul A., Cribbs, Cynthia M., Koehler, Konrad F., Sharkey, Nancy A., Herald, Cherry L., Kamano, Yoshiaki, Pettit, George R., Blumberg, Peter M.

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A broad-spectrum antifungal from the marine sponge Hyrtios erecta von PETTIT, R. K, MCALLISTER, S. C, PETTIT, G. R, HERALD, C. L, JOHNSON, J. M, CICHACZ, Z. A

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Bryostatin 1, an activator of protein kinase C, inhibits tumor promotion by phorbol esters in SENCAR mouse skin von Hennings, Henry, Blumberg, Peter M., Pettit, George R., Herald, Cherry L., Shores, Robert, Yuspa, Stuart H.

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Partial parallelism and partial blockade by bryostatin 1 of effects of phorbol ester tumor promoters on primary mouse epidermal cells von SAKO, T, YUSPA, S. H, HERALD, C. L, PETTIT, G. R, BLUMBERG, P. M

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The inhibitory effects of bryostatin 1 administration on the growth of rabbit papillomas von Bodily, Jason M, Hoopes, David J, Roeder, Beverly L, Gilbert, Sharon G, Pettit, George R, Herald, Cherry L, Rollins, Darin N, Robison, Richard A

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Bryostatin 1, an activator of protein kinase C, mimics as well as inhibits biological effects of the phorbol ester TPA in vivo and in vitro von Gschwendt, M., Fürstenberger, G., Rose-John, S., Rogers, M., Kittstein, W., Pettit, G. R., Herald, C.L., Marks, F.

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The Spongistatins, Potently Cytotoxic Inhibitors of Tubulin Polymerization, Bind in a Distinct Region of the Vinca Domain von Bai, Ruoli, Taylor, George F, Cichacz, Zbigniew A, Herald, Cherry L, Kepler, John A, Pettit, George R, Hamel, Ernest

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An Improved Source of Bryostatin 10, Bugula neritina from the Gulf of Aomori, Japan von Kamano, Yoshiaki, Zhang, Hui-Ping, Hino, Akiya, Yoshida, Motoyuki, Pettit, George R, Herald, Cherry L, Itokawa, Hideji

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Isolation and structure of the cell growth inhibitory constituents from the western Pacific marine sponge Axinella sp von Pettit, G R, Herald, C L, Boyd, M R, Leet, J E, Dufresne, C, Doubek, D L, Schmidt, J M, Cerny, R L, Hooper, J N, Rützler, K C

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Demonstration of sub-nanomolar affinity of bryostatin 1 for the phorbol ester receptor in rat brain von de Vries, David J., Herald, Cherry L., Pettit, George R., Blumberg, Peter M.

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Isolation and structure of bryostatins 14 and 15 von Pettit, G.R., Gao, F., Sengupta, D., Coll, J.C., Herald, C.L., Doubek, D.L., Schmidt, J.M., van Camp, J.R., Rudloe, J.J., Nieman, R.A.

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Action of Phorbol Esters, Bryostatins, and Retinoic Acid on Cholesterol Sulfate Synthesis: Relation to the Multistep Process of Differentiation in Human Epidermal Keratinocytes von Jetten, Anton M., George, Margaret A., Pettit, George R., Herald, Cherry L., Rearick, James I.

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Inhibition by bryostatin 1 of the phorbol ester-induced blockage of differentiation in hexamethylene bisacetamide-treated Friend erythroleukemia cells von DELL'AQUILA, M. L, NGUYEN, H. T, HERALD, C. L, PETTIT, G. R, BLUMBERG, P. M

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Differential effects of bryostatins and phorbol esters on arachidonic acid metabolite release and epidermal growth factor binding in C3H 10T1/2 cells von DELL'AQUILA, M. L, HERALD, C. L, KAMANO, Y, PETTIT, G. R, BLUMBERG, P. M

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Antineoplastic Agents. 340. Isolation and Structural Elucidation of Bryostatins 16−18 von Pettit, George R, Gao, Feng, Blumberg, Peter M, Herald, Cherry L, Coll, John C, Kamano, Yoshiaki, Lewin, Nancy E, Schmidt, Jean M, Chapuis, Jean-Charles

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Relationship of Bugula neritina (Bryozoa) antineoplastic constituents to the yellow sponge Lissodendoryx isodictyalis von Pettit, G. R., Kamano, Yoshiaki, Herald, C. L., Schmidt, J. M., Zubrod, C. G.

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Contrasting duration of inhibition of cell-cell communication in primary mouse epidermal cells by phorbol 12,13-dibutyrate and by bryostatin 1 von PASTI, G, RIVEDAL, E, YUSPA, S. H, HERALD, C. L, PETTIT, G. R, BLUMBERG, P. M

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Synthetic conversion of bryostatin 2 to bryostatin 1 and related bryopyrans von Pettit, George R, Sengupta, Dipanjan, Herald, Cherry L, Sharkey, Nancy A, Blumberg, Peter M

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