Targeting FXR and FGF19 to Treat Metabolic Diseases-Lessons Learned From Bariatric Surgery von Bozadjieva, Nadejda, Heppner, Kristy M, Seeley, Randy J

Volltext

GLP-1 based therapeutics: simultaneously combating T2DM and obesity von Heppner, Kristy M, Perez-Tilve, Diego

Volltext

MECHANISMS IN ENDOCRINOLOGY: Regulation of glucose metabolism by the ghrelin system: multiple players and multiple actions von Heppner, Kristy M, Tong, Jenny

Volltext

Expression and Distribution of Glucagon-Like Peptide-1 Receptor mRNA, Protein and Binding in the Male Nonhuman Primate (Macaca mulatta) Brain von Heppner, Kristy M, Kirigiti, Melissa, Secher, Anna, Paulsen, Sarah Juel, Buckingham, Rikley, Pyke, Charles, Knudsen, Lotte B, Vrang, Niels, Grove, Kevin L

Volltext

Direct Control of Brown Adipose Tissue Thermogenesis by Central Nervous System Glucagon-Like Peptide-1 Receptor Signaling von LOCKIE, Sarah H, HEPPNER, Kristy M, RAHMOUNI, Kamal, OLDFIELD, Brian J, TSCHÖP, Matthias H, PEREZ-TILVE, Diego, CHAUDHARY, Nilika, CHABENNE, Joseph R, MORGAN, Donald A, VEYRAT-DUREBEX, Christelle, ANANTHAKRISHNAN, Gayathri, ROHNER-JEANRENAUD, Françoise, DRUCKER, Daniel J, DIMARCHI, Richard

Volltext

Intestinal-derived FGF15 protects against deleterious effects of vertical sleeve gastrectomy in mice von Bozadjieva-Kramer, Nadejda, Shin, Jae Hoon, Shao, Yikai, Gutierrez-Aguilar, Ruth, Li, Ziru, Heppner, Kristy M., Chiang, Samuel, Vargo, Sara G., Granger, Katrina, Sandoval, Darleen A., MacDougald, Ormond A., Seeley, Randy J.

Volltext

Both acyl and des-acyl ghrelin regulate adiposity and glucose metabolism via central nervous system ghrelin receptors von Heppner, Kristy M, Piechowski, Carolin L, Müller, Anne, Ottaway, Nickki, Sisley, Stephanie, Smiley, David L, Habegger, Kirk M, Pfluger, Paul T, Dimarchi, Richard, Biebermann, Heike, Tschöp, Matthias H, Sandoval, Darleen A, Perez-Tilve, Diego

Volltext

Ablation of ghrelin O-acyltransferase does not improve glucose intolerance or body adiposity in mice on a leptin-deficient ob/ob background von Kirchner, Henriette, Heppner, Kristy M, Holland, Jenna, Kabra, Dhiraj, Tschöp, Matthias H, Pfluger, Paul T

Volltext

The GOAT-ghrelin system is not essential for hypoglycemia prevention during prolonged calorie restriction von Yi, Chun-Xia, Heppner, Kristy M, Kirchner, Henriette, Tong, Jenny, Bielohuby, Maximillian, Gaylinn, Bruce D, Müller, Timo D, Bartley, Erin, Davis, Harold W, Zhao, Yongmei, Joseph, Anupama, Kruthaupt, Traci, Ottaway, Nickki, Kabra, Dhiraj, Habegger, Kirk M, Benoit, Stephen C, Bidlingmaier, Martin, Thorner, Michael O, Perez-Tilve, Diego, Tschöp, Matthias H, Pfluger, Paul T

Volltext

Regulation of glucose metabolism by the ghrelin system: multiple players and multiple actions von HEPPNER, Kristy M, TONG, Jenny

Volltext

Reelin is modulated by diet-induced obesity and has direct actions on arcuate proopiomelanocortin neurons von Roberts, Brandon L., Bennett, Baylin J., Bennett, Camdin M., Carroll, Julie M., Dalbøge, Louise S., Hall, Colin, Hassouneh, Wafa, Heppner, Kristy M., Kirigiti, Melissa A., Lindsley, Sarah R., Tennant, Katherine G., True, Cadence A., Whittle, Andrew, Wolf, Anitra C., Roberts, Charles T., Tang-Christensen, Mads, Sleeman, Mark W., Cowley, Michael A., Grove, Kevin L., Kievit, Paul

Volltext

GLP-1R Agonism Enhances Adjustable Gastric Banding in Diet-Induced Obese Rats von HABEGGER, Kirk M, KIRCHNER, Henriette, MÜLLER, Timo D, PEREZ-TILVE, Diego, PFLUGER, Paul T, OBICI, Silvana, DIMARCHI, Richard D, D'ALESSIO, David A, SEELEY, Randy J, TSCHOP, Matthias H, YI, Chun-Xia, HEPPNER, Kristy M, SWEENEY, Dan, OTTAWAY, Nickki, HOLLAND, Jenna, AMBURGY, Sarah, RAVER, Christine, KRISHNA, Radhakrishna

Volltext

Ghrelin in the Control of Energy, Lipid, and Glucose Metabolism von Heppner, Kristy M., Müller, Timo D., Tong, Jenny, Tschöp, Matthias H.

Volltext

The ghrelin O-acyltransferase–ghrelin system: a novel regulator of glucose metabolism von Heppner, Kristy M, Tong, Jenny, Kirchner, Henriette, Nass, Ralf, Tschöp, Matthias H

Volltext

Acylation Type Determines Ghrelin's Effects on Energy Homeostasis in Rodents von Heppner, Kristy M, Chaudhary, Nilika, Müller, Timo D, Kirchner, Henriette, Habegger, Kirk M, Ottaway, Nickki, Smiley, David L, DiMarchi, Richard, Hofmann, Susanna M, Woods, Stephen C, Sivertsen, Bjørn, Holst, Birgitte, Pfluger, Paul T, Perez-Tilve, Diego, Tschöp, Matthias H

Volltext

Contribution of brown adipose tissue activity to the control of energy balance by GLP-1 receptor signalling in mice von Heppner, Kristy M., Marks, Sarah, Holland, Jenna, Ottaway, Nickki, Smiley, David, Dimarchi, Richard, Perez-Tilve, Diego

Volltext

FGF21 decreases body weight without reducing food intake or bone mineral density in high-fat fed obese rhesus macaque monkeys von Andersen, Birgitte, Straarup, Ellen M., Heppner, Kristy M., Takahashi, Diana L., Raffaele, Virginia, Dissen, Gregory A., Lewandowski, Katherine, Bödvarsdottir, Thóra B., Raun, Kirsten, Grove, Kevin L., Kievit, Paul

Volltext

Fibroblast Growth Factor 21 Mediates Specific Glucagon Actions von HABEGGER, Kirk M, STEMMER, Kerstin, KRISHNA, Radha, ARAFAT, Ayman M, KONKAR, Anish, BELLI, Sara, KAPPS, Martin, WOODS, Stephen C, HOFMANN, Susanna M, D'ALESSIO, David, PFLUGER, Paul T, PEREZ-TILVE, Diego, CHENG, Christine, SEELEY, Randy J, KONISHI, Morichika, ITOH, Nobuyujki, KHARITONENKOV, Alexei, SPRANGER, Joachim, DIMARCHI, Richard D, TSCHÖP, Matthias H, MÜLLER, Timo D, HEPPNER, Kristy M, OTTAWAY, Nickki, HOLLAND, Jenna, HEMBREE, Jazzminn L, SMILEY, David, GELFANOV, Vasily

Volltext

p62 links β-adrenergic input to mitochondrial function and thermogenesis von Müller, Timo D, Lee, Sang Jun, Jastroch, Martin, Kabra, Dhiraj, Stemmer, Kerstin, Aichler, Michaela, Abplanalp, Bill, Ananthakrishnan, Gayathri, Bhardwaj, Nakul, Collins, Sheila, Divanovic, Senad, Endele, Max, Finan, Brian, Gao, Yuanqing, Habegger, Kirk M, Hembree, Jazzmin, Heppner, Kristy M, Hofmann, Susanna, Holland, Jenna, Küchler, Daniela, Kutschke, Maria, Krishna, Radha, Lehti, Maarit, Oelkrug, Rebecca, Ottaway, Nickki, Perez-Tilve, Diego, Raver, Christine, Walch, Axel K, Schriever, Sonja C, Speakman, John, Tseng, Yu-Hua, Diaz-Meco, Maria, Pfluger, Paul T, Moscat, Jorge, Tschöp, Matthias H

Volltext

Duodenal nutrient exclusion improves metabolic syndrome and stimulates villus hyperplasia von Habegger, Kirk M, Al-Massadi, Omar, Heppner, Kristy M, Myronovych, Andriy, Holland, Jenna, Berger, Jose, Yi, Chun-Xia, Gao, Yuanging, Lehti, Maarit, Ottaway, Nickki, Amburgy, Sarah, Raver, Christine, Müller, Timo D, Pfluger, Paul T, Kohli, Rohit, Perez-Tilve, Diego, Seeley, Randy J, Tschöp, Matthias H

Volltext