Mouse models of nonalcoholic steatohepatitis in preclinical drug development von Hansen, Henrik H., Feigh, Michael, Veidal, Sanne S., Rigbolt, Kristoffer T., Vrang, Niels, Fosgerau, Keld

Volltext

Metabolic and hepatic effects of liraglutide, obeticholic acid and elafibranor in diet-induced obese mouse models of biopsy-confirmed nonalcoholic steatohepatitis von Tølbøl, Kirstine S, Kristiansen, Maria Nb, Hansen, Henrik H, Veidal, Sanne S, Rigbolt, Kristoffer Tg, Gillum, Matthew P, Jelsing, Jacob, Vrang, Niels, Feigh, Michael

Volltext

Towards a standard diet-induced and biopsy-confirmed mouse model of non-alcoholic steatohepatitis: Impact of dietary fat source von Boland, Michelle L, Oró, Denise, Tølbøl, Kirstine S, Thrane, Sebastian T, Nielsen, Jens Christian, Cohen, Taylor S, Tabor, David E, Fernandes, Fiona, Tovchigrechko, Andrey, Veidal, Sanne S, Warrener, Paul, Sellman, Bret R, Jelsing, Jacob, Feigh, Michael, Vrang, Niels, Trevaskis, James L, Hansen, Henrik H

Volltext

Identification and Metabolic Profiling of a Novel Human Gut-derived LEAP2 Fragment von Hagemann, Christoffer A, Zhang, Chen, Hansen, Henrik H, Jorsal, Tina, Rigbolt, Kristoffer T G, Madsen, Martin R, Bergmann, Natasha C, Heimbürger, Sebastian M N, Falkenhahn, Mechthilde, Theis, Stefan, Breitschopf, Kristin, Holm, Stephanie, Hedegaard, Morten A, Christensen, Mikkel B, Vilsbøll, Tina, Holst, Birgitte, Vrang, Niels, Jelsing, Jacob, Knop, Filip K

Volltext

Hepatoprotective effects of semaglutide, lanifibranor and dietary intervention in the GAN diet‐induced obese and biopsy‐confirmed mouse model of NASH von Møllerhøj, Mathias B., Veidal, Sanne S., Thrane, Kirstine Tølbøl, Oró, Denise, Overgaard, Agnete, Salinas, Casper Gravesen, Madsen, Martin Rønn, Pfisterer, Larissa, Vyberg, Mogens, Simon, Eric, Broermann, Andre, Vrang, Niels, Jelsing, Jacob, Feigh, Michael, Hansen, Henrik H.

Volltext

Characterization of combined linagliptin and Y2R agonist treatment in diet-induced obese mice von Hansen, Henrik H., Grønlund, Rikke V., Baader-Pagler, Tamara, Haebel, Peter, Tammen, Harald, Larsen, Leif Kongskov, Jelsing, Jacob, Vrang, Niels, Klein, Thomas

Volltext

Whole-brain activation signatures of weight-lowering drugs von Hansen, Henrik H., Perens, Johanna, Roostalu, Urmas, Skytte, Jacob Lercke, Salinas, Casper Gravesen, Barkholt, Pernille, Thorbek, Ditte Dencker, Rigbolt, Kristoffer T.G., Vrang, Niels, Jelsing, Jacob, Hecksher-Sørensen, Jacob

Volltext

Quantitative whole-brain 3D imaging of tyrosine hydroxylase-labeled neuron architecture in the mouse MPTP model of Parkinson's disease von Roostalu, Urmas, Salinas, Casper B G, Thorbek, Ditte D, Skytte, Jacob L, Fabricius, Katrine, Barkholt, Pernille, John, Linu M, Jurtz, Vanessa Isabell, Knudsen, Lotte Bjerre, Jelsing, Jacob, Vrang, Niels, Hansen, Henrik H, Hecksher-Sørensen, Jacob

Volltext

Effect of captopril on post-infarction remodelling visualized by light sheet microscopy and echocardiography von Roostalu, Urmas, Thisted, Louise, Skytte, Jacob Lercke, Salinas, Casper Gravesen, Pedersen, Philip Juhl, Hecksher-Sørensen, Jacob, Rolin, Bidda, Hansen, Henrik H., MacKrell, James G., Christie, Robert M., Vrang, Niels, Jelsing, Jacob, Zois, Nora Elisabeth

Volltext

Disease Progression and Pharmacological Intervention in a Nutrient-Deficient Rat Model of Nonalcoholic Steatohepatitis von Tølbøl, Kirstine S., Stierstorfer, Birgit, Rippmann, Jörg F., Veidal, Sanne S., Rigbolt, Kristoffer T. G., Schönberger, Tanja, Gillum, Matthew P., Hansen, Henrik H., Vrang, Niels, Jelsing, Jacob, Feigh, Michael, Broermann, Andre

Volltext

Application of the Physical Disector Principle for Quantification of Dopaminergic Neuronal Loss in a Rat 6-Hydroxydopamine Nigral Lesion Model of Parkinson's Disease von Fabricius, Katrine, Barkholt, Pernille, Jelsing, Jacob, Hansen, Henrik H

Volltext

3D light-sheet fluorescence microscopy in preclinical and clinical drug discovery von Roostalu, Urmas, Hansen, Henrik H., Hecksher-Sørensen, Jacob

Volltext

Changes in Binding of [123I]CLINDE, a High-Affinity Translocator Protein 18 kDa (TSPO) Selective Radioligand in a Rat Model of Traumatic Brain Injury von Donat, Cornelius K., Gaber, Khaled, Meixensberger, Jürgen, Brust, Peter, Pinborg, Lars H., Hansen, Henrik H., Mikkelsen, Jens D.

Volltext

Kv7 channels: interaction with dopaminergic and serotonergic neurotransmission in the CNS von Hansen, Henrik H., Waroux, Olivier, Seutin, Vincent, Jentsch, Thomas J., Aznar, Susana, Mikkelsen, Jens D.

Volltext

Anti‐hypertensive treatment preserves appetite suppression while preventing cardiovascular adverse effects of tesofensine in rats von Bentzen, Bo Hjorth, Grunnet, Morten, Hyveled‐Nielsen, Lars, Sundgreen, Claus, Lassen, Jørgen Buus, Hansen, Henrik H.

Volltext

Alterations in hypothalamic gene expression following Roux-en-Y gastric bypass von Barkholt, Pernille, Pedersen, Philip J, Hay-Schmidt, Anders, Jelsing, Jacob, Hansen, Henrik H, Vrang, Niels

Volltext

NMDA Antagonist Inhibits the Extracellular Signal-Regulated Kinase Pathway and Suppresses Cancer Growth von Andrzej Stepulak, Sifringer, Marco, Rzeski, Wojciech, Stefanie Endesfelder, Alexander Gratopp, Elena E. Pohl, Bittigau, Petra, Ursula Felderhoff-Mueser, Angela M. Kaindl, Christoph Bührer, Henrik H. Hansen, Marta Stryjecka-Zimmer, Turski, Lechoslaw, Ikonomidou, Chrysanthy

Volltext

Mechanisms leading to disseminated apoptosis following NMDA receptor blockade in the developing rat brain von Hansen, Henrik H, Briem, Tim, Dzietko, Mark, Sifringer, Marco, Voss, Alexander, Rzeski, Wojciech, Zdzisinska, Barbara, Thor, Friederike, Heumann, Rolf, Stepulak, Andrzej, Bittigau, Petra, Ikonomidou, Chrysanthy

Volltext

A3907, a systemic ASBT inhibitor, improves cholestasis in mice by multiorgan activity and shows translational relevance to humans von Caballero-Camino, Francisco J, Rodrigues, Pedro M, Wångsell, Fredrik, Agirre-Lizaso, Aloña, Olaizola, Paula, Izquierdo-Sanchez, Laura, Perugorria, Maria J, Bujanda, Luis, Angelin, Bo, Straniero, Sara, Wallebäck, Anna, Starke, Ingemar, Gillberg, Per-Göran, Strängberg, Ellen, Bonn, Britta, Mattsson, Jan P, Madsen, Martin R, Hansen, Henrik H, Lindström, Erik, Åkerblad, Peter, Banales, Jesus M

Volltext

1665-P: Whole-Brain Activation Signatures of Weight-Lowering Drugs von DALBOEGE, LOUISE S., TOZZI, MARCO, SALINAS, CASPER G., PORSGAARD, TRINE, THORBEK, DITTE D., SKYTTE, JACOB L., ROOSTALU, URMAS, HANSEN, HENRIK H., PERENS, JOHANNA, HECKSHER-SØRENSEN, JACOB

Volltext