Pulmonary Aspergillosis in Patients with Suspected Ventilator-associated Pneumonia in UK ICUs von Loughlin, Laura, Hellyer, Thomas P., White, P. Lewis, McAuley, Danny F., Morris, Andrew Conway, Posso, Raquel B., Richardson, Malcolm D., Denning, David W., Simpson, A. John, McMullan, Ronan

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The Intensive Care Society recommended bundle of interventions for the prevention of ventilator-associated pneumonia von Hellyer, Thomas P, Ewan, Victoria, Wilson, Peter, Simpson, A John

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Bayesian sample size determination for diagnostic accuracy studies von Wilson, Kevin J., Williamson, S. Faye, Allen, A. Joy, Williams, Cameron J., Hellyer, Thomas P., Lendrem, B. Clare

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Randomised controlled trial of GM-CSF in critically ill patients with impaired neutrophil phagocytosis von Pinder, Emma M, Rostron, Anthony J, Hellyer, Thomas P, Ruchaud-Sparagano, Marie-Helene, Scott, Jonathan, Macfarlane, James G, Wiscombe, Sarah, Widdrington, John D, Roy, Alistair I, Linnett, Vanessa C, Baudouin, Simon V, Wright, Stephen E, Chadwick, Thomas, Fouweather, Tony, Juss, Jatinder K, Chilvers, Edwin R, Bowett, Susan A, Parker, Jennie, McAuley, Daniel F, Conway Morris, Andrew, Simpson, A John

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A retrospective propensity-score-matched cohort study of the impact of procalcitonin testing on antibiotic use in hospitalized patients during the first wave of COVID-19 von Sandoe, Jonathan A T, Grozeva, Detelina, Albur, Mahableshwar, Bond, Stuart E, Brookes-Howell, Lucy, Dark, Paul, Euden, Joanne, Hamilton, Ryan, Hellyer, Thomas P, Henley, Josie, Hopkins, Susan, Howard, Philip, Howdon, Daniel, Knox-Macaulay, Chikezie, Llewelyn, Martin J, Maboshe, Wakunyambo, McCullagh, Iain J, Ogden, Margaret, Parsons, Helena K, Partridge, David G, Powell, Neil, Prestwich, Graham, Shaw, Dominick, Shinkins, Bethany, Szakmany, Tamas, Thomas-Jones, Emma, Todd, Stacy, West, Robert M, Carrol, Enitan D, Pallmann, Philip

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Nitration of chemokine CXCL8 acts as a natural mechanism to limit acute inflammation von Thompson, Sarah, Pang, Chong Yun, Sepuru, Krishna Mohan, Cambier, Seppe, Hellyer, Thomas P., Scott, Jonathan, Simpson, A. John, Proost, Paul, Kirby, John A., Rajarathnam, Krishna, Sheerin, Neil S., Ali, Simi

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Biomarker-guided antibiotic stewardship in suspected ventilator-associated pneumonia (VAPrapid2): a randomised controlled trial and process evaluation von Hellyer, Thomas P, McAuley, Daniel F, Walsh, Timothy S, Anderson, Niall, Conway Morris, Andrew, Singh, Suveer, Dark, Paul, Roy, Alistair I, Perkins, Gavin D, McMullan, Ronan, Emerson, Lydia M, Blackwood, Bronagh, Wright, Stephen E, Kefala, Kallirroi, O'Kane, Cecilia M, Baudouin, Simon V, Paterson, Ross L, Rostron, Anthony J, Agus, Ashley, Bannard-Smith, Jonathan, Robin, Nicole M, Welters, Ingeborg D, Bassford, Christopher, Yates, Bryan, Spencer, Craig, Laha, Shondipon K, Hulme, Jonathan, Bonner, Stephen, Linnett, Vanessa, Sonksen, Julian, Van Den Broeck, Tina, Boschman, Gert, Keenan, DW James, Scott, Jonathan, Allen, A Joy, Phair, Glenn, Parker, Jennie, Bowett, Susan A, Simpson, A John

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Could host response guide VAP treatment? No answer yet – Authors' reply von Hellyer, Thomas P, Simpson, A John

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Developing a model for decision-making around antibiotic prescribing for patients with COVID-19 pneumonia in acute NHS hospitals during the first wave of the COVID-19 pandemic: qua... von Henley, Josie, Brookes-Howell, Lucy, Euden, Joanne, Pallmann, Philip, Llewelyn, Martin, Howard, Philip, Powell, Neil, Dark, Paul, Szakmany, Tamas, Hellyer, Thomas P, Albur, Mahableshwar, Hamilton, Ryan, Prestwich, Graham, Ogden, Margaret, Maboshe, Wakunyambo, Sandoe, Jonathan, Thomas-Jones, Emma, Carrol, Enitan, Albur, Mahableshwar, Bond, Stuart E, Gerver, Sarah M, Hopkins, Susan, McCullagh, Iain J, Parsons, Helena, Partridge, David G, Shaw, Dominick, Shinkins, Bethany, Todd, Stacy, West, Robert M

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16S pan-bacterial PCR can accurately identify patients with ventilator-associated pneumonia von Conway Morris, Andrew, Gadsby, Naomi, McKenna, James P, Hellyer, Thomas P, Dark, Paul, Singh, Suveer, Walsh, Timothy S, McAuley, Danny F, Templeton, Kate, Simpson, A John, McMullan, Ronan

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Role of immunosuppression in an antibiotic stewardship intervention and its association with clinical outcomes and antibiotic use: protocol for an observational study (RISC-sepsis) von Scott, Jonathan, Trevi, Loredana, McNeil, Hannah, Ewen, Tom, Mawson, Phil, McDonald, David, Filby, Andrew, Lall, Ranjit, Booth, Katie, Boschman, Gert, Melkebeek, Vesna, Perkins, Gavin, McMullan, Ronan, McAuley, Daniel F, McCullagh, Iain J, Walsh, Timothy, Rostron, Anthony, Shankar-Hari, Manu, Dark, Paul, Simpson, A John, Conway Morris, Andrew, Hellyer, Thomas P

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Use of Procalcitonin during the First Wave of COVID-19 in the Acute NHS Hospitals: A Retrospective Observational Study von Powell, Neil, Howard, Philip, Llewelyn, Martin J., Szakmany, Tamas, Albur, Mahableswhar, Bond, Stuart E., Euden, Joanne, Brookes-Howell, Lucy, Dark, Paul, Hellyer, Thomas P., Hopkins, Susan, McCullagh, Iain J., Ogden, Margaret, Pallmann, Philip, Parsons, Helena, Partridge, David G., Shaw, Dominick E., Shinkins, Bethany, Todd, Stacy, Thomas-Jones, Emma, West, Robert, Carrol, Enitan D., Sandoe, Jonathan A. T.

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Exchange protein directly activated by cyclic AMP (EPAC) activation reverses neutrophil dysfunction induced by β2 -agonists, corticosteroids, and critical illness von Scott, Jonathan, MPhil, Harris, Graham J., MBBS, MRes, Pinder, Emma M., MRCP(UK), Macfarlane, James G., MRCP(UK), Hellyer, Thomas P., MRCP(UK), Rostron, Anthony J., PhD, FRCP, Conway Morris, Andrew, PhD, FRCA, Thickett, David R., DM, FRCP, Perkins, Gavin D., MD, FRCP, McAuley, Daniel F., MD, FRCP, Widdrington, John D., MBBS, MRes, Wiscombe, Sarah, MBChB, Baudouin, Simon V., MD, FRCP, Roy, Alistair I., FFICM, Linnett, Vanessa C., FRCA, Wright, Stephen E., FRCA, Ruchaud-Sparagano, Marie-Hélène, PhD, Simpson, A. John, PhD, FRCP(Edin)

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Diagnostic accuracy of pulmonary host inflammatory mediators in the exclusion of ventilator-acquired pneumonia von Hellyer, Thomas P, Morris, Andrew Conway, McAuley, Daniel F, Walsh, Timothy S, Anderson, Niall H, Singh, Suveer, Dark, Paul, Roy, Alistair I, Baudouin, Simon V, Wright, Stephen E, Perkins, Gavin D, Kefala, Kallirroi, Jeffels, Melinda, McMullan, Ronan, O'Kane, Cecilia M, Spencer, Craig, Laha, Shondipon, Robin, Nicole, Gossain, Savita, Gould, Kate, Ruchaud-Sparagano, Marie-Hélène, Scott, Jonathan, Browne, Emma M, MacFarlane, James G, Wiscombe, Sarah, Widdrington, John D, Dimmick, Ian, Laurenson, Ian F, Nauwelaers, Frans, Simpson, A John

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Procalcitonin Evaluation of Antibiotic Use in COVID-19 Hospitalised Patients (PEACH): Protocol for a Retrospective Observational Study von Euden, Joanne, Pallmann, Philip, Grozeva, Detelina, Albur, Mahableshwar, Bond, Stuart E, Brookes-Howell, Lucy, Dark, Paul, Hellyer, Thomas, Hopkins, Susan, Howard, Philip, Llewelyn, Martin J, Maboshe, Wakunyambo, McCullagh, Iain J, Ogden, Margaret, Parsons, Helena, Partridge, David, Powell, Neil, Shaw, Dominick, Shinkins, Bethany, Szakmany, Tamas, Todd, Stacy, Thomas-Jones, Emma, West, Robert M, Carrol, Enitan D, Sandoe, Jonathan A T

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Effectiveness of biomarker-based exclusion of ventilator-acquired pneumonia to reduce antibiotic use (VAPrapid-2): study protocol for a randomised controlled trial von Hellyer, Thomas P, Anderson, Niall H, Parker, Jennie, Dark, Paul, Van Den Broeck, Tina, Singh, Suveer, McMullan, Ronan, Agus, Ashley M, Emerson, Lydia M, Blackwood, Bronagh, Gossain, Savita, Walsh, Tim S, Perkins, Gavin D, Conway Morris, Andrew, McAuley, Daniel F, Simpson, A John

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Exchange protein directly activated by cyclic AMP (EPAC) activation reverses neutrophil dysfunction induced by beta 2-agonists, corticosteroids, and critical illness von Scott, Jonathan, Harris, Graham J, Pinder, Emma M, Macfarlane, James G, Hellyer, Thomas P, Rostron, Anthony J, Conway Morris, Andrew, Thickett, David R, Perkins, Gavin D, McAuley, Daniel F, Widdrington, John D, Wiscombe, Sarah, Baudouin, Simon V, Roy, Alistair I, Linnett, Vanessa C, Wright, Stephen E, Ruchaud-Sparagano, Marie-Helene, Simpson, AJohn

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Development and implementation of a customised rapid syndromic diagnostic test for severe pneumonia von Navapurkar, Vilas, Bartholdson Scott, Josefin, Maes, Mailis, Hellyer, Thomas P, Higginson, Ellen, Forrest, Sally, Pereira-Dias, Joana, Parmar, Surendra, Heasman-Hunt, Emma, Polgarova, Petra, Brown, Joanne, Titti, Lissamma, Smith, William PW, Scott, Jonathan, Rostron, Anthony, Routledge, Matthew, Sapsford, David, Török, M. Estée, McMullan, Ronan, Enoch, David A, Wong, Vanessa, Curran, Martin D, Brown, Nicholas M, Simpson, A John, Herre, Jurgen, Dougan, Gordon, Conway Morris, Andrew

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Erratum to: 'Effectiveness of biomarker-based exclusion of ventilator-acquired pneumonia to reduce antibiotic use (VAPrapid-2): study protocol for a randomised controlled trial' von Hellyer, Thomas P, Anderson, Niall H, Parker, Jennie, Dark, Paul, Van Den Broeck, Tina, Singh, Suveer, McMullan, Ronan, Agus, Ashley M, Emerson, Lydia M, Blackwood, Bronagh, Gossain, Savita, Walsh, Tim S, Perkins, Gavin D, Morris, Andrew Conway, McAuley, Daniel F, Simpson, A John

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A national survey of the diagnosis and management of suspected ventilator-associated pneumonia von Browne, Emma, Hellyer, Thomas P, Baudouin, Simon V, Conway Morris, Andrew, Linnett, Vanessa, McAuley, Danny F, Perkins, Gavin D, Simpson, A John

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