Making immunotherapy ‘cold’ tumours ‘hot’ by chemotherapy-induced mutations—a misconception von Helleday, T.

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Making immunotherapy "cold' tumours "hot' by chemotherapy-induced mutationsa misconception von Helleday, T

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PARP inhibitor receives FDA breakthrough therapy designation in castration resistant prostate cancer: beyond germline BRCA mutations von Helleday, T.

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Homologous recombination in cancer development, treatment and development of drug resistance von HELLEDAY, Thomas

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Cancer phenotypic lethality, exemplified by the non-essential MTH1 enzyme being required for cancer survival von Helleday, T.

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Chemotherapy-induced toxicity—a secondary effect caused by released DNA? von Helleday, T.

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Managing COVID-19 in the oncology clinic and avoiding the distraction effect von Cortiula, F., Pettke, A., Bartoletti, M., Puglisi, F., Helleday, T.

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CHD1: a new treatment biomarker for recombination deficiency in castration resistant prostate cancer? von Helleday, T.

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MTH1 inhibitors in cancer treatment von Helleday, T.

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6: Targeting MTH1 prevents sanitation of oxidised dNTP pools and causes cancer-selective DNA damage and cell death von Helleday, T

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Increased replication initiation and conflicts with transcription underlie Cyclin E-induced replication stress von Jones, R M, Mortusewicz, O, Afzal, I, Lorvellec, M, García, P, Helleday, T, Petermann, E

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PC4 promotes genome stability and DNA repair through binding of ssDNA at DNA damage sites von Mortusewicz, O, Evers, B, Helleday, T

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Small-molecule-mediated OGG1 inhibition attenuates pulmonary inflammation and lung fibrosis in a murine lung fibrosis model von Tanner, L., Single, A. B., Bhongir, R. K. V., Heusel, M., Mohanty, T., Karlsson, C. A. Q., Pan, L., Clausson, C-M., Bergwik, J., Wang, K., Andersson, C. K., Oommen, R. M., Erjefält, J. S., Malmström, J., Wallner, O., Boldogh, I., Helleday, T., Kalderén, C., Egesten, A.

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Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy von Huber, Kilian V. M., Salah, Eidarus, Radic, Branka, Gridling, Manuela, Elkins, Jonathan M., Stukalov, Alexey, Jemth, Ann-Sofie, Göktürk, Camilla, Sanjiv, Kumar, Strömberg, Kia, Pham, Therese, Berglund, Ulrika Warpman, Colinge, Jacques, Bennett, Keiryn L., Loizou, Joanna I., Helleday, Thomas, Knapp, Stefan, Superti-Furga, Giulio

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Rational design and validation of a Tip60 histone acetyltransferase inhibitor von Gao, Chunxia, Bourke, Emer, Scobie, Martin, Famme, Melina Arcos, Koolmeister, Tobias, Helleday, Thomas, Eriksson, Leif A., Lowndes, Noel F., Brown, James A. L.

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Validation and development of MTH1 inhibitors for treatment of cancer von Warpman Berglund, U., Sanjiv, K., Gad, H., Kalderén, C., Koolmeister, T., Pham, T., Gokturk, C., Jafari, R., Maddalo, G., Seashore-Ludlow, B., Chernobrovkin, A., Manoilov, A., Pateras, I.S., Rasti, A., Jemth, A.-S., Almlöf, I., Loseva, O., Visnes, T., Einarsdottir, B.O., Gaugaz, F.Z., Saleh, A., Platzack, B., Wallner, O.A., Vallin, K.S.A., Henriksson, M., Wakchaure, P., Borhade, S., Herr, P., Kallberg, Y., Baranczewski, P., Homan, E.J., Wiita, E., Nagpal, V., Meijer, T., Schipper, N., Rudd, S.G., Bräutigam, L., Lindqvist, A., Filppula, A., Lee, T.-C., Artursson, P., Nilsson, J.A., Gorgoulis, V.G., Lehtiö, J., Zubarev, R.A., Scobie, M., Helleday, T.

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The spliceosome U2 snRNP factors promote genome stability through distinct mechanisms; transcription of repair factors and R-loop processing von Tanikawa, M, Sanjiv, K, Helleday, T, Herr, P, Mortusewicz, O

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The First Structure of Human MTHFD2L and Its Implications for the Development of Isoform‐Selective Inhibitors von Scaletti, Emma R., Gustafsson Westergren, Robert, Andersson, Yasmin, Wiita, Elisee, Henriksson, Martin, Homan, Evert J., Jemth, Ann‐Sofie, Helleday, Thomas, Stenmark, Pål

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Transcription-associated recombination in eukaryotes: link between transcription, replication and recombination von Gottipati, Ponnari, Helleday, Thomas

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Genotoxicity of alcohol is linked to DNA replication-associated damage and homologous recombination repair von Kotova, Natalia, Vare, Daniel, Schultz, Niklas, Gradecka Meesters, Dobroslawa, Stepnik, Maciej, Grawé, Jan, Helleday, Thomas, Jenssen, Dag

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