Rapidly acquired resistance to EGFR tyrosine kinase inhibitors in NSCLC cell lines through de-repression of FGFR2 and FGFR3 expression von Ware, Kathryn E, Marshall, Marianne E, Heasley, Lydia R, Marek, Lindsay, Hinz, Trista K, Hercule, Paula, Helfrich, Barbara A, Doebele, Robert C, Heasley, Lynn E

Volltext

Barasertib (AZD1152), a Small Molecule Aurora B Inhibitor, Inhibits the Growth of SCLC Cell Lines In Vitro and In Vivo von Helfrich, Barbara A, Kim, Jihye, Gao, Dexiang, Chan, Daniel C, Zhang, Zhiyong, Tan, Aik-Choon, Bunn, Jr, Paul A

Volltext

Tankyrase and the Canonical Wnt Pathway Protect Lung Cancer Cells from EGFR Inhibition von CASAS-SELVES, Matias, KIM, Jihye, DEGREGORI, James, ZHIYONG ZHANG, HELFRICH, Barbara A, DEXIANG GAO, PORTER, Christopher C, SCARBOROUGH, Hannah A, BUNNJR, Paul A, CHAN, Daniel C, AIK CHOON TAN

Volltext

Epithelial to mesenchymal transition predicts gefitinib resistance in cell lines of head and neck squamous cell carcinoma and non–small cell lung carcinoma von Frederick, Barbara A, Helfrich, Barbara A, Coldren, Christopher D, Zheng, Di, Chan, Dan, Bunn, Jr, Paul A, Raben, David

Volltext

FGFR1 mRNA and Protein Expression, not Gene Copy Number, Predict FGFR TKI Sensitivity across All Lung Cancer Histologies von WYNES, Murry W, HINZ, Trista K, DZIADZIUSZKO, Rafal, JASSEM, Jacek, WOJTYLAK, Szymon, SEJDA, Aleksandra, GOZGIT, Joseph M, BUNN, Paul A, CAMIDGE, D. Ross, TAN, Aik-Choon, HIRSCH, Fred R, HEASLEY, Lynn E, DEXIANG GAO, MARTINI, Michael, MAREK, Lindsay A, WARE, Kathryn E, EDWARDS, Michael G, BÖHM, Diana, PERNER, Sven, HELFRICH, Barbara A

Volltext

Fibroblast Growth Factor (FGF) and FGF Receptor-Mediated Autocrine Signaling in Non-Small-Cell Lung Cancer Cells von Marek, Lindsay, Ware, Kathryn E, Fritzsche, Alexa, Hercule, Paula, Helton, Wallace R, Smith, Jennifer E, McDermott, Lee A, Coldren, Christopher D, Nemenoff, Raphael A, Merrick, Daniel T, Helfrich, Barbara A, Bunn, Jr, Paul A, Heasley, Lynn E

Volltext

AZ1366: An Inhibitor of Tankyrase and the Canonical Wnt Pathway that Limits the Persistence of Non-Small Cell Lung Cancer Cells Following EGFR Inhibition von Scarborough, Hannah A, Helfrich, Barbara A, Casás-Selves, Matias, Schuller, Alwin G, Grosskurth, Shaun E, Kim, Jihye, Tan, Aik-Choon, Chan, Daniel C, Zhang, Zhiyong, Zaberezhnyy, Vadym, Bunn, Paul A, DeGregori, James

Volltext

ZEB1-responsive genes in non-small cell lung cancer von Gemmill, Robert M, Roche, Joëlle, Potiron, Vincent A, Nasarre, Patrick, Mitas, Michael, Coldren, Chris D, Helfrich, Barbara A, Garrett-Mayer, Elizabeth, Bunn, Paul A, Drabkin, Harry A

Volltext

Eribulin inhibits the growth of small cell lung cancer cell lines alone and with radiotherapy von Helfrich, Barbara A., Gao, Dexiang, Bunn, Paul A.

Volltext

Restoring E-cadherin expression increases sensitivity to epidermal growth factor receptor inhibitors in lung cancer cell lines von Witta, Samir E, Gemmill, Robert M, Hirsch, Fred R, Coldren, Christopher D, Hedman, Karla, Ravdel, Larisa, Helfrich, Barbara, Dziadziuszko, Rafal, Chan, Daniel C, Sugita, Michio, Chan, Zeng, Baron, Anna, Franklin, Wilbur, Drabkin, Harry A, Girard, Luc, Gazdar, Adi F, Minna, John D, Bunn, Jr, Paul A

Volltext

Epidermal growth factor receptor family in lung cancer and premalignancy von Franklin, Wilbur A, Veve, Robert, Hirsch, Fred R, Helfrich, Barbara A, Bunn, Paul A

Volltext

Antitumor Activity of the Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor Gefitinib (ZD1839, Iressa) in Non–Small Cell Lung Cancer Cell Lines Correlates with Gene... von HELFRICH, Barbara A, RABEN, David, HIRSCH, Fred R, GAZDAR, Adi, MINNA, John, BUNN, Paul A, VARELLA-GARCIA, Marileila, GUSTAFSON, Dan, CHAN, Daniel C, BEMIS, Lynne, COLDREN, Chris, BARON, Anna, CHAN ZENG, FRANKLIN, Wilbur A

Volltext

Baseline Gene Expression Predicts Sensitivity to Gefitinib in Non–Small Cell Lung Cancer Cell Lines von Coldren, Christopher D, Helfrich, Barbara A, Witta, Samir E, Sugita, Michio, Lapadat, Razvan, Zeng, Chan, Barón, Anna, Franklin, Wilbur A, Hirsch, Fred R, Geraci, Mark W, Bunn, Jr, Paul A

Volltext

Expression of Her-2/neu in Human Lung Cancer Cell Lines by Immunohistochemistry and Fluorescence in Situ Hybridization and its Relationship to in Vitro Cytotoxicity by Trastuzumab... von BUNN, Paul A, HELFRICH, Barbara, SORIANO, Ariel F, FRANKLIN, Wilbur A, VARELLA-GARCIA, Marileila, HIRSCH, Fred R, BARON, Anna, ZENG, Chan, CHAN, Daniel C

Volltext

ZD1839, a selective epidermal growth factor receptor tyrosine kinase inhibitor, alone and in combination with radiation and chemotherapy as a new therapeutic strategy in non–small... von Raben, David, Helfrich, Barbara A., Chan, Dan, Johnson, Gary, Bunn, Paul A.

Volltext

Altered HOX and WNT7A Expression in Human Lung Cancer von Calvo, Roser, West, James, Franklin, Wilbur, Erickson, Paul, Bemis, Lynne, Li, Efang, Helfrich, Barbara, Bunn, Paul, Roche, Joelle, Brambilla, Elisabeth, Rosell, Rafael, Gemmill, Robert M., Drabkin, Harry A.

Volltext

Bradykinin Antagonist Dimer, CU201, Inhibits the Growth of Human Lung Cancer Cell Lines by a "Biased Agonist" Mechanism von Chan, Daniel, Gera, Lajos, Stewart, John, Helfrich, Barbara, Verella-Garcia, Marileila, Johnson, Gary, Baron, Anna, Yang, Jie, Puck, Theodore, Bunn, Paul

Volltext

Exisulind in Combination with Docetaxel Inhibits Growth and Metastasis of Human Lung Cancer and Prolongs Survival in Athymic Nude Rats with Orthotopic Lung Tumors von CHAN, Daniel C, EARLE, Keith A, ALILA, Hector, NELSON, Peter, BUNN, Paul A, ZHAO, Tom L. M, HELFRICH, Barbara, CHAN ZENG, BARON, Anna, WHITEHEAD, Clark M, PIAZZA, Gary, PAMUKCU, Rifat, THOMPSON, W. Joseph

Volltext

Bradykinin Antagonist Dimer, CU201, Inhibits the Growth of Human Lung Cancer Cell Lines in Vitro and in Vivo and Produces Synergistic Growth Inhibition in Combination with Other An... von CHAN, Daniel C, GERA, Lajos, STEWART, John M, HELFRICH, Barbara, ZHAO, Tom Limin, WAN YONG FENG, CHAN, Kenneth K, COVEY, Joseph M, BUNN, Paul A

Volltext

Reversal of Anticancer Multidrug Resistance by the Ardeemins von Chou, Ting-Chao, Depew, Kristopher M., Zheng, Yu-Huang, Safer, Michelle L., Chan, Daniel, Helfrich, Barbara, Zatorska, Danuta, Zatorski, Andrzej, Bornmann, William, Danishefsky, Samuel J.

Volltext