Efficacy of tyrosine kinase inhibitors in Ph-like acute lymphoblastic leukemia harboring ABL-class rearrangements von Tanasi, Ilaria, Ba, Ibrahima, Sirvent, Nicolas, Braun, Thorsten, Cuccuini, Wendy, Ballerini, Paola, Duployez, Nicolas, Tanguy-Schmidt, Aline, Tamburini, Jérôme, Maury, Sébastien, Doré, Eric, Himberlin, Chantal, Duclos, Cédric, Chevallier, Patrice, Rousselot, Philippe, Bonifacio, Massimiliano, Cavé, Hélène, Baruchel, André, Dombret, Hervé, Soulier, Jean, Landman-Parker, Judith, Boissel, Nicolas, Clappier, Emmanuelle

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Favorable outcome of NUTM1-rearranged infant and pediatric B cell precursor acute lymphoblastic leukemia in a collaborative international study von Boer, Judith M., Valsecchi, Maria Grazia, Hormann, Femke M., Antić, Željko, Zaliova, Marketa, Schwab, Claire, Cazzaniga, Giovanni, Arfeuille, Chloé, Cavé, Hélène, Attarbaschi, Andishe, Strehl, Sabine, Escherich, Gabriele, Imamura, Toshihiko, Ohki, Kentaro, Grüber, Tanja A., Sutton, Rosemary, Pastorczak, Agata, Lammens, Tim, Lambert, Frédéric, Li, Chi Kong, Carrillo de Santa Pau, Enrique, Hoffmann, Steve, Möricke, Anja, Harrison, Christine J., Den Boer, Monique L., De Lorenzo, Paola, Stam, Ronald W., Bergmann, Anke K., Pieters, Rob

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Clinical characteristics and outcomes of B-ALL with ZNF384 rearrangements: a retrospective analysis by the Ponte di Legno Childhood ALL Working Group von Hirabayashi, Shinsuke, Butler, Ellie R., Ohki, Kentaro, Kiyokawa, Nobutaka, Bergmann, Anke K., Möricke, Anja, Boer, Judith M., Cavé, Hélène, Cazzaniga, Giovanni, Yeoh, Allen Eng Juh, Sanada, Masashi, Imamura, Toshihiko, Inaba, Hiroto, Mullighan, Charles, Loh, Mignon L., Norén-Nyström, Ulrika, Pastorczak, Agata, Shih, Lee-Yung, Zaliova, Marketa, Pui, Ching-Hon, Haas, Oskar A., Harrison, Christine J., Moorman, Anthony V., Manabe, Atsushi

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Determinants of CD19-positive vs CD19-negative relapse after tisagenlecleucel for B-cell acute lymphoblastic leukemia von Dourthe, Marie-Emilie, Rabian, Florence, Yakouben, Karima, Chevillon, Florian, Cabannes-Hamy, Aurélie, Méchinaud, Françoise, Grain, Audrey, Chaillou, Delphine, Rahal, Ilhem, Caillat-Zucman, Sophie, Lesprit, Emmanuelle, Naudin, Jérôme, Roupret-Serzec, Julie, Parquet, Nathalie, Brignier, Anne, Guérin-El Khourouj, Valérie, Lainey, Elodie, Caye-Eude, Aurélie, Cavé, Hélène, Clappier, Emmanuelle, Mathis, Stéphanie, Azoulay, Elie, Dalle, Jean Hugues, Dhédin, Nathalie, Madelaine, Isabelle, Larghero, Jérôme, Boissel, Nicolas, Baruchel, André

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Activating Mutations of RRAS2 Are a Rare Cause of Noonan Syndrome von Capri, Yline, Flex, Elisabetta, Krumbach, Oliver H.F., Carpentieri, Giovanna, Cecchetti, Serena, Lißewski, Christina, Rezaei Adariani, Soheila, Schanze, Denny, Brinkmann, Julia, Piard, Juliette, Pantaleoni, Francesca, Lepri, Francesca R., Goh, Elaine Suk-Ying, Chong, Karen, Stieglitz, Elliot, Meyer, Julia, Kuechler, Alma, Bramswig, Nuria C., Sacharow, Stephanie, Strullu, Marion, Vial, Yoann, Vignal, Cédric, Kensah, George, Cuturilo, Goran, Kazemein Jasemi, Neda S., Dvorsky, Radovan, Monaghan, Kristin G., Vincent, Lisa M., Cavé, Hélène, Verloes, Alain, Ahmadian, Mohammad R., Tartaglia, Marco, Zenker, Martin

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Human MLL/KMT2A gene exhibits a second breakpoint cluster region for recurrent MLL–USP2 fusions von Meyer, Claus, Lopes, Bruno A., Caye-Eude, Aurélie, Cavé, Hélène, Arfeuille, Chloé, Cuccuini, Wendy, Sutton, Rosemary, Venn, Nicola C., Oh, Seung Hwan, Tsaur, Grigory, Escherich, Gabriele, Feuchtinger, Tobias, Kosasih, Hansen J., Khaw, Seong L., Ekert, Paul G., Pombo-de-Oliveira, Maria S., Bidet, Audrey, Djahanschiri, Bardya, Ebersberger, Ingo, Zaliova, Marketa, Zuna, Jan, Zermanova, Zuzana, Juvonen, Vesa, Grümayer, Renate Panzer, Fazio, Grazia, Cazzaniga, Gianni, Larghero, Patrizia, Emerenciano, Mariana, Marschalek, Rolf

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Predictive value of minimal residual disease in Philadelphia-chromosome-positive acute lymphoblastic leukemia treated with imatinib in the European intergroup study of post-inducti... von Cazzaniga, Giovanni, De Lorenzo, Paola, Alten, Julia, Röttgers, Silja, Hancock, Jeremy, Saha, Vaskar, Castor, Anders, Madsen, Hans O, Gandemer, Virginie, Cavé, Hélène, Leoni, Veronica, Köhler, Rolf, Ferrari, Giulia M, Bleckmann, Kirsten, Pieters, Rob, van der Velden, Vincent, Stary, Jan, Zuna, Jan, Escherich, Gabriele, Stadt, Udo Zur, Aricò, Maurizio, Conter, Valentino, Schrappe, Martin, Valsecchi, Maria Grazia, Biondi, Andrea

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Acute lymphoblastic leukemia in children with Down syndrome: a retrospective analysis from the Ponte di Legno study group von Buitenkamp, Trudy D., Izraeli, Shai, Zimmermann, Martin, Forestier, Erik, Heerema, Nyla A., van den Heuvel-Eibrink, Marry M., Pieters, Rob, Korbijn, Carin M., Silverman, Lewis B., Schmiegelow, Kjeld, Liang, Der-Cheng, Horibe, Keizo, Arico, Maurizio, Biondi, Andrea, Basso, Giuseppe, Rabin, Karin R., Schrappe, Martin, Cario, Gunnar, Mann, Georg, Morak, Maria, Panzer-Grümayer, Renate, Mondelaers, Veerle, Lammens, Tim, Cavé, Hélène, Stark, Batia, Ganmore, Ithamar, Moorman, Anthony V., Vora, Ajay, Hunger, Stephen P., Pui, Ching-Hon, Mullighan, Charles G., Manabe, Atsushi, Escherich, Gabriele, Kowalczyk, Jerzy R., Whitlock, James A., Zwaan, C. Michel

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LIN28B overexpression defines a novel fetal-like subgroup of juvenile myelomonocytic leukemia von Helsmoortel, Hetty H., Bresolin, Silvia, Lammens, Tim, Cavé, Hélène, Noellke, Peter, Caye, Aurélie, Ghazavi, Farzaneh, de Vries, Andrica, Hasle, Henrik, Labarque, Veerle, Masetti, Riccardo, Stary, Jan, van den Heuvel-Eibrink, Marry M., Philippé, Jan, Van Roy, Nadine, Benoit, Yves, Speleman, Frank, Niemeyer, Charlotte, Flotho, Christian, Basso, Giuseppe, te Kronnie, Geertruy, Van Vlierberghe, Pieter, De Moerloose, Barbara

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Dexamethasone (6 mg/m2/day) and prednisolone (60 mg/m2/day) were equally effective as induction therapy for childhood acute lymphoblastic leukemia in the EORTC CLG 58951 randomized... von Domenech, Carine, Suciu, Stefan, De Moerloose, Barbara, Mazingue, Françoise, Plat, Geneviève, Ferster, Alina, Uyttebroeck, Anne, Sirvent, Nicolas, Lutz, Patrick, Yakouben, Karima, Munzer, Martine, Röhrlich, Pierre, Plantaz, Dominique, Millot, Frederic, Philippet, Pierre, Dastugue, Nicole, Girard, Sandrine, Cavé, Hélène, Benoit, Yves, Bertrandfor, Yves

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Myeloid Dysregulation in a Human Induced Pluripotent Stem Cell Model of PTPN11-Associated Juvenile Myelomonocytic Leukemia von Mulero-Navarro, Sonia, Sevilla, Ana, Roman, Angel C., Lee, Dung-Fang, D’Souza, Sunita L., Pardo, Sherly, Riess, Ilan, Su, Jie, Cohen, Ninette, Schaniel, Christoph, Rodriguez, Nelson A., Baccarini, Alessia, Brown, Brian D., Cavé, Hélène, Caye, Aurélie, Strullu, Marion, Yalcin, Safak, Park, Christopher Y., Dhandapany, Perundurai S., Yongchao, Ge, Edelmann, Lisa, Bahieg, Sawsan, Raynal, Patrick, Flex, Elisabetta, Tartaglia, Marco, Moore, Kateri A., Lemischka, Ihor R., Gelb, Bruce D.

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Late Recurrence of Childhood T-Cell Acute Lymphoblastic Leukemia Frequently Represents a Second Leukemia Rather Than a Relapse: First Evidence for Genetic Predisposition von SZCZEPANSKI, Tomasz, VAN DER VELDEN, Vincent H. J, ZUR STADT, Udo, CAMPANA, Dario, SCHRAUDER, André, SUTTON, Rosemary, VAN WERING, Elisabeth, MEIJERINK, Jules P. P, VAN DONGEN, Jacques J. M, WAANDERS, Esmé, KUIPER, Roland P, VAN VLIERBERGHE, Pieter, GRUHN, Bernd, ECKERT, Cornelia, PANZER-GRÜMAYER, Renate, BASSO, Giuseppe, CAVE, Hélène

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LEOPARD syndrome-associated SHP2 mutation confers leanness and protection from diet-induced obesity von Tajan, Mylène, Batut, Aurélie, Cadoudal, Thomas, Deleruyelle, Simon, Le Gonidec, Sophie, Saint Laurent, Céline, Vomscheid, Maëlle, Wanecq, Estelle, Tréguer, Karine, De Rocca Serra-Nédélec, Audrey, Vinel, Claire, Marques, Marie-Adeline, Pozzo, Joffrey, Kunduzova, Oksana, Salles, Jean-Pierre, Tauber, Maithé, Raynal, Patrick, Cavé, Hélène, Edouard, Thomas, Valet, Philippe, Yart, Armelle

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Long-term Metabolic and Socioeducational Outcomes of Transient Neonatal Diabetes: A Longitudinal and Cross-sectional Study von Le Bourgeois, Fleur, Beltrand, Jacques, Baz, Baz, Julla, Jean-Baptiste, Riveline, Jean-Pierre, Simon, Albane, Flechtner, Isabelle, Ait Djoudi, Malek, Fauret-Amsellem, Anne-Laure, Vial, Yoann, Scharfmann, Raphael, Sommet, Julie, Boudou, Philippe, Cavé, Hélène, Polak, Michel, Gautier, Jean-François, Busiah, Kanetee

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Prolonged versus standard native E. coli asparaginase therapy in childhood acute lymphoblastic leukemia and non-Hodgkin lymphoma: final results of the EORTC-CLG randomized phase II... von Mondelaers, Veerle, Suciu, Stefan, De Moerloose, Barbara, Ferster, Alina, Mazingue, Françoise, Plat, Geneviève, Yakouben, Karima, Uyttebroeck, Anne, Lutz, Patrick, Costa, Vitor, Sirvent, Nicolas, Plouvier, Emmanuel, Munzer, Martine, Poirée, Maryline, Minckes, Odile, Millot, Frédéric, Plantaz, Dominique, Maes, Philip, Hoyoux, Claire, Cavé, Hélène, Rohrlich, Pierre, Bertrand, Yves, Benoit, Yves

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Criteria for evaluating response and outcome in clinical trials for children with juvenile myelomonocytic leukemia von Niemeyer, Charlotte M, Loh, Mignon L, Cseh, Annamaria, Cooper, Todd, Dvorak, Christopher C, Chan, Rebecca, Xicoy, Blanca, Germing, Ulrich, Kojima, Seiji, Manabe, Atsushi, Dworzak, Michael, De Moerloose, Barbara, Starý, Jan, Smith, Owen P, Masetti, Riccardo, Catala, Albert, Bergstraesser, Eva, Ussowicz, Marek, Fabri, Oskana, Baruchel, André, Cavé, Hélène, Zwaan, Michel, Locatelli, Franco, Hasle, Henrik, van den Heuvel-Eibrink, Marry M, Flotho, Christian, Yoshimi, Ayami

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Disruption of a Novel Krüppel-like Transcription Factor p300-regulated Pathway for Insulin Biosynthesis Revealed by Studies of the c.-331 INS Mutation Found in Neonatal Diabetes Me... von Bonnefond, Amélie, Lomberk, Gwen, Buttar, Navtej, Busiah, Kanetee, Vaillant, Emmanuel, Lobbens, Stéphane, Yengo, Loïc, Dechaume, Aurélie, Mignot, Brigitte, Simon, Albane, Scharfmann, Raphaël, Neve, Bernadette, Tanyolaç, Sinan, Hodoglugil, Ugur, Pattou, François, Cavé, Hélène, Iovanna, Juan, Stein, Roland, Polak, Michel, Vaxillaire, Martine, Froguel, Philippe, Urrutia, Raul

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Identification of Distinct Molecular Phenotypes in Acute Megakaryoblastic Leukemia by Gene Expression Profiling von Bourquin, Jean-Pierre, Subramanian, Aravind, Langebrake, Claudia, Reinhardt, Dirk, Bernard, Olivier, Ballerini, Paola, Baruchel, André, Cavé, Hélène, Dastugue, Nicole, Hasle, Henrik, Kaspers, Gertjan L., Lessard, Michel, Michaux, Lucienne, Vyas, Paresh, van Wering, Elisabeth, Zwaan, Christian M., Golub, Todd R., Orkin, Stuart H.

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Natural history of GATA2 deficiency in a survey of 79 French and Belgian patients von Donadieu, Jean, Lamant, Marie, Fieschi, Claire, de Fontbrune, Flore Sicre, Caye, Aurélie, Ouachee, Marie, Beaupain, Blandine, Bustamante, Jacinta, Poirel, Hélène A, Isidor, Bertrand, Van Den Neste, Eric, Neel, Antoine, Nimubona, Stanislas, Toutain, Fabienne, Barlogis, Vincent, Schleinitz, Nicolas, Leblanc, Thierry, Rohrlich, Pierre, Suarez, Felipe, Ranta, Dana, Chahla, Wadih Abou, Bruno, Bénédicte, Terriou, Louis, Francois, Sylvie, Lioure, Bruno, Ahle, Guido, Bachelerie, Françoise, Preudhomme, Claude, Delabesse, Eric, Cave, Hélène, Bellanné-Chantelot, Christine, Pasquet, Marlène

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Mitchell–Riley Syndrome: Improving Clinical Outcomes and Searching for Functional Impact of RFX-6 Mutations von Passone, Caroline de Gouveia Buff, Vermillac, Gaëlle, Staels, Willem, Besancon, Alix, Kariyawasam, Dulanjalee, Godot, Cécile, Lambe, Cécile, Talbotec, Cécile, Girard, Muriel, Chardot, Christophe, Berteloot, Laureline, Hachem, Taymme, Lapillonne, Alexandre, Poidvin, Amélie, Storey, Caroline, Neve, Mathieu, Stan, Cosmina, Dugelay, Emmanuelle, Fauret-Amsellem, Anne-Laure, Capri, Yline, Cavé, Hélène, Ybarra, Marina, Chandra, Vikash, Scharfmann, Raphaël, Bismuth, Elise, Polak, Michel, Carel, Jean Claude, Pigneur, Bénédicte, Beltrand, Jacques

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