Structural basis of ligand recognition in 5-HT3 receptors von Kesters, Divya, Thompson, Andrew J, Brams, Marijke, van Elk, René, Spurny, Radovan, Geitmann, Matthis, Villalgordo, Jose M, Guskov, Albert, Helena Danielson, U, Lummis, Sarah C R, Smit, August B, Ulens, Chris

Volltext

Molecular blueprint of allosteric binding sites in a homologue of the agonist-binding domain of the α7 nicotinic acetylcholine receptor von Spurny, Radovan, Debaveye, Sarah, Farinha, Ana, Veys, Ken, Vos, Ann M., Gossas, Thomas, Atack, John, Bertrand, Sonia, Bertrand, Daniel, Danielson, U. Helena, Tresadern, Gary, Ulens, Chris

Volltext

Monitoring drug-target interactions through target engagement-mediated amplification on arrays and in situ von Al-Amin, Rasel A, Johansson, Lars, Abdurakhmanov, Eldar, Landegren, Nils, Löf, Liza, Arngården, Linda, Blokzijl, Andries, Svensson, Richard, Hammond, Maria, Lönn, Peter, Haybaeck, Johannes, Kamali-Moghaddam, Masood, Jensen, Annika Jenmalm, Danielson, U Helena, Artursson, Per, Lundbäck, Thomas, Landegren, Ulf

Volltext

Kinetically Selective Inhibitors of Human Carbonic Anhydrase Isozymes I, II, VII, IX, XII, and XIII von Talibov, Vladimir O, Linkuvienė, Vaida, Matulis, Daumantas, Danielson, U. Helena

Volltext

Structural and Functional Analysis of Hepatitis C Virus Strain JFH1 Polymerase von SIMISTER, Philip, SCHMITT, Melanie, GEITMANN, Matthis, WICHT, Oliver, HELENA DANIELSON, U, KLEIN, Rahel, BRESSANELLI, Stéphane, LOHMANN, Volker

Volltext

Development of a novel therapeutic vaccine carrier that sustains high antibody titers against several targets simultaneously von Saupe, Falk, Reichel, Matthias, Huijbers, Elisabeth J. M., Femel, Julia, Markgren, Per-Olof, Evalena Andersson, C., Deindl, Sebastian, Helena Danielson, U., Hellman, Lars T., Olsson, Anna-Karin

Volltext

The Crystal Structure of Tyrosinase from Verrucomicrobium spinosum Reveals It to Be an Atypical Bacterial Tyrosinase von Fekry, Mostafa, Dave, Khyati K., Badgujar, Dilip, Hamnevik, Emil, Aurelius, Oskar, Dobritzsch, Doreen, Danielson, U. Helena

Volltext

Characterization of interactions between hepatitis C virus NS5B polymerase, annexin A2 and RNA - effects on NS5B catalysis and allosteric inhibition von Solbak, Sara M Ø, Abdurakhmanov, Eldar, Vedeler, Anni, Danielson, U Helena

Volltext

Biophysics in drug discovery: impact, challenges and opportunities von Renaud, Jean-Paul, Chung, Chun-wa, Danielson, U. Helena, Egner, Ursula, Hennig, Michael, Hubbard, Roderick E., Nar, Herbert

Volltext

The Allosteric Regulation of Β-Ureidopropionase Depends on Fine-Tuned Stability of Active-Site Loops and Subunit Interfaces von Cederfelt, Daniela, Badgujar, Dilip, Au Musse, Ayan, Lohkamp, Bernhard, Danielson, U Helena, Dobritzsch, Doreen

Volltext

Monitoring drug–serum protein interactions for early ADME prediction through Surface Plasmon Resonance technology von Fabini, Edoardo, Danielson, U. Helena

Volltext

Macrocyclic Peptides Uncover a Novel Binding Mode for Reversible Inhibitors of LSD1 von Yang, Jie, Talibov, Vladimir O, Peintner, Stefan, Rhee, Claire, Poongavanam, Vasanthanathan, Geitmann, Matthis, Sebastiano, Matteo Rossi, Simon, Bernd, Hennig, Janosch, Dobritzsch, Doreen, Danielson, U. Helena, Kihlberg, Jan

Volltext

Ultralarge Virtual Screening Identifies SARS-CoV‑2 Main Protease Inhibitors with Broad-Spectrum Activity against Coronaviruses von Luttens, Andreas, Gullberg, Hjalmar, Abdurakhmanov, Eldar, Vo, Duy Duc, Akaberi, Dario, Talibov, Vladimir O, Nekhotiaeva, Natalia, Vangeel, Laura, De Jonghe, Steven, Jochmans, Dirk, Krambrich, Janina, Tas, Ali, Lundgren, Bo, Gravenfors, Ylva, Craig, Alexander J, Atilaw, Yoseph, Sandström, Anja, Moodie, Lindon W. K, Lundkvist, Åke, van Hemert, Martijn J, Neyts, Johan, Lennerstrand, Johan, Kihlberg, Jan, Sandberg, Kristian, Danielson, U. Helena, Carlsson, Jens

Volltext

Structural Changes of Mercaptohexanol Self-Assembled Monolayers on Gold and Their Influence on Impedimetric Aptamer Sensors von Xu, Xingxing, Makaraviciute, Asta, Kumar, Shalen, Wen, Chenyu, Sjödin, Martin, Abdurakhmanov, Eldar, Danielson, U. Helena, Nyholm, Leif, Zhang, Zhen

Volltext

Production of stable and pure ZC3H11A – An extensively disordered RNA binding protein von Fekry, Mostafa, Stenberg, Gun, Dobritzsch, Doreen, Danielson, U. Helena

Volltext

Analysis of the leakage of gene repression by an artificial TetR-regulated promoter in cyanobacteria von Huang, Hsin-Ho, Seeger, Christian, Danielson, U Helena, Lindblad, Peter

Volltext

Efficient screening of marine extracts for protease inhibitors by combining FRET based activity assays and surface plasmon resonance spectroscopy based binding assays von Christopeit, Tony, Øverbø, Kersti, Danielson, U Helena, Nilsen, Inge W

Volltext

Unraveling the Bivalent and Rapid Interactions Between a Multivalent RNA Recognition Motif and RNA: A Kinetic Approach von Pérez-Ropero, Guillermo, Pérez-Ràfols, Anna, Martelli, Tommasso, Danielson, U. Helena, Buijs, Jos

Volltext

Inhibition of HIV-1 by non-nucleoside reverse transcriptase inhibitors via an induced fit mechanism—Importance of slow dissociation and relaxation rates for antiviral efficacy von Elinder, Malin, Selhorst, Philippe, Vanham, Guido, Öberg, Bo, Vrang, Lotta, Danielson, U. Helena

Volltext

Interaction Kinetic Characterization of HIV-1 Reverse Transcriptase Non-nucleoside Inhibitor Resistance von Geitmann, Matthis, Unge, Torsten, Danielson, U. Helena

Volltext