Human Fatty Liver Disease: Old Questions and New Insights von Cohen, Jonathan C., Horton, Jay D., Hobbs, Helen H.

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The PNPLA3 variant associated with fatty liver disease (I148M) accumulates on lipid droplets by evading ubiquitylation von BasuRay, Soumik, Smagris, Eriks, Cohen, Jonathan C., Hobbs, Helen H.

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Accumulation of PNPLA3 on lipid droplets is the basis of associated hepatic steatosis von BasuRay, Soumik, Wang, Yang, Smagris, Eriks, Cohen, Jonathan C., Hobbs, Helen H.

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PNPLA3, CGI‐58, and Inhibition of Hepatic Triglyceride Hydrolysis in Mice von Wang, Yang, Kory, Nora, BasuRay, Soumik, Cohen, Jonathan C, Hobbs, Helen H

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Adiposity amplifies the genetic risk of fatty liver disease conferred by multiple loci von Stender, Stefan, Kozlitina, Julia, Nordestgaard, Børge G, Tybjærg-Hansen, Anne, Hobbs, Helen H, Cohen, Jonathan C

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Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease von Cohen, Jonathan C, Hobbs, Helen H, Romeo, Stefano, Kozlitina, Julia, Xing, Chao, Pertsemlidis, Alexander, Cox, David, Pennacchio, Len A, Boerwinkle, Eric

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Inactivation of Tm6sf2, a Gene Defective in Fatty Liver Disease, Impairs Lipidation but Not Secretion of Very Low Density Lipoproteins von Smagris, Eriks, Gilyard, Shenise, BasuRay, Soumik, Cohen, Jonathan C., Hobbs, Helen H.

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PCSK9: a convertase that coordinates LDL catabolism von Horton, Jay D., Cohen, Jonathan C., Hobbs, Helen H.

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Inactivation of ANGPTL3 reduces hepatic VLDL-triglyceride secretion von Wang, Yan, Gusarova, Viktoria, Banfi, Serena, Gromada, Jesper, Cohen, Jonathan C, Hobbs, Helen H

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Expression and Characterization of a PNPLA3 Protein Isoform (I148M) Associated with Nonalcoholic Fatty Liver Disease von Huang, Yongcheng, Cohen, Jonathan C., Hobbs, Helen H.

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Pnpla3I148M knockin mice accumulate PNPLA3 on lipid droplets and develop hepatic steatosis von Smagris, Eriks, BasuRay, Soumik, Li, John, Huang, Yongcheng, Lai, Ka‐man V., Gromada, Jesper, Cohen, Jonathan C., Hobbs, Helen H.

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Atypical angiopoietin-like protein that regulates ANGPTL3 von Quagliarini, Fabiana, Wang, Yan, Kozlitina, Julia, Grishin, Nick V, Hyde, Rhonda, Boerwinkle, Eric, Valenzuela, David M, Murphy, Andrew J, Cohen, Jonathan C, Hobbs, Helen H

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Mice lacking ANGPTL8 (Betatrophin) manifest disrupted triglyceride metabolism without impaired glucose homeostasis von Wang, Yan, Quagliarini, Fabiana, Gusarova, Viktoria, Gromada, Jesper, Valenzuela, David M., Cohen, Jonathan C., Hobbs, Helen H.

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ANGPTL8/Betatrophin Does Not Control Pancreatic Beta Cell Expansion von Gusarova, Viktoria, Alexa, Corey A., Na, Erqian, Stevis, Panayiotis E., Xin, Yurong, Bonner-Weir, Susan, Cohen, Jonathan C., Hobbs, Helen H., Murphy, Andrew J., Yancopoulos, George D., Gromada, Jesper

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Rare loss-of-function mutations in ANGPTL family members contribute to plasma triglyceride levels in humans von Romeo, Stefano, Yin, Wu, Kozlitina, Julia, Pennacchio, Len A, Boerwinkle, Eric, Hobbs, Helen H, Cohen, Jonathan C

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Science, serendipity, and the single degree von Hobbs, Helen H

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Crystal structure of the human sterol transporter ABCG5/ABCG8 von Lee, Jyh-Yeuan, Kinch, Lisa N., Borek, Dominika M., Wang, Jin, Wang, Junmei, Urbatsch, Ina L., Xie, Xiao-Song, Grishin, Nikolai V., Cohen, Jonathan C., Otwinowski, Zbyszek, Hobbs, Helen H., Rosenbaum, Daniel M.

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Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease von Kozlitina, Julia, Smagris, Eriks, Stender, Stefan, Nordestgaard, Børge G, Zhou, Heather H, Tybjærg-Hansen, Anne, Vogt, Thomas F, Hobbs, Helen H, Cohen, Jonathan C

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Contribution of a genetic risk score to ethnic differences in fatty liver disease von Kubiliun, Maddie J., Cohen, Jonathan C., Hobbs, Helen H., Kozlitina, Julia

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Biocatalysis in Supercritical Fluids, in Fluorous Solvents, and under Solvent-Free Conditions von Hobbs, Helen R, Thomas, Neil R

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