Fast Iterative Synthetic Approach toward Identification of Novel Highly Selective p38 MAP Kinase Inhibitors von Röhm, Sandra, Berger, Benedict-Tilman, Schröder, Martin, Chaikuad, Apirat, Winkel, Rob, Hekking, Koen F. W, Benningshof, Jorg J. C, Müller, Gerhard, Tesch, Roberta, Kudolo, Mark, Forster, Michael, Laufer, Stefan, Knapp, Stefan

Volltext

Development of Potent Mcl‑1 Inhibitors: Structural Investigations on Macrocycles Originating from a DNA-Encoded Chemical Library Screen von Hekking, Koen F. W., Maroto, Sergio, van Kekem, Kees, Haasjes, Frank S., Slootweg, Jack C., Oude Alink, Patrick G. B., Dirks, Ron, Sardana, Malvika, Bolster, Marjon G., Kuijpers, Brian, Smith, Dennis, Doodeman, Robin, Scheepstra, Marcel, Zech, Birgit, Mulvihill, Mark, Renzetti, Louis M., Babiss, Lee, Centrella, Paolo A., Clark, Matthew A., Cuozzo, John W., Guié, Marie-Aude, Sigel, Eric, Habeshian, Sevan, Hupp, Christopher D., Liu, Julie, Thomson, Heather A., Zhang, Ying, Keefe, Anthony D., Müller, Gerhard, Gremmen, Stijn

Volltext

A Ring-Closing Metathesis Approach to Cyclic α,β-Dehydroamino Acids von Hekking, Koen F. W., Waalboer, Dennis C. J., Moelands, Marcel A. H., van Delft, Floris L., Rutjes, Floris P. J. T.

Volltext

Discovery of 2,4-1 H -Imidazole Carboxamides as Potent and Selective TAK1 Inhibitors von Veerman, Johan J N, Bruseker, Yorik B, Damen, Eddy, Heijne, Erik H, van Bruggen, Wendy, Hekking, Koen F W, Winkel, Rob, Hupp, Christopher D, Keefe, Anthony D, Liu, Julie, Thomson, Heather A, Zhang, Ying, Cuozzo, John W, McRiner, Andrew J, Mulvihill, Mark J, van Rijnsbergen, Peter, Zech, Birgit, Renzetti, Louis M, Babiss, Lee, Müller, Gerhard

Volltext

Bivalent Ligands for Protein Degradation in Drug Discovery von Scheepstra, Marcel, Hekking, Koen F.W., van Hijfte, Luc, Folmer, Rutger H.A.

Volltext

Synthesis of Versatile Building Blocks through Asymmetric Hydrogenation of Functionalized Itaconic Acid Mono-Esters von Hekking, Koen F. W., Lefort, Laurent, de Vries, André H. M., van Delft, Floris L., Schoemaker, Hans E., de Vries, Johannes G., Rutjes, Floris P. J. T.

Volltext

Effects of Extended Aryl-Substituted Bisoxazoline Ligands in Asymmetric Synthesis - Efficient Synthesis and Application of 4,4′-Bis(1-Naphthyl)-, 4,4′-Bis(2-Naphthyl)- and 4,4′-Bis... von van Lingen, Hester L., van Delft, Floris L., Storcken, Roy P. M., Hekking, Koen F. W., Klaassen, Anouk, Smits, Jan J. M., Ruskowska, Patrycja, Frelek, Jadwiga, Rutjes, Floris P. J. T.

Volltext

Cobalt Chloride Complexes of N 3 and N 4 Donor Ligands von Kooistra, T. Martijn, Hekking, Koen F. W., Knijnenburg, Quinten, de Bruin, Bas, Budzelaar, Peter H. M., de Gelder, René, Smits, Jan M. M., Gal, Anton W.

Volltext

Heterocyclic derivatives, pharmaceutical compositions and their use in the treatment or amelioration of cancer von EERLAND, Martijn, FOLMER, Rutger, FABRITIUS, Charles-Henry, GRUBER, Dorothea, FLÜCKIGER-MANGUAL, Stefanie, HEKKING, Koen F. W, VEERMAN, Johan J. N

Volltext bestellen

HETEROCYCLIC DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND THEIR USE IN THE TREATMENT OR AMELIORATION OF CANCER von EERLAND, Martijn, FOLMER, Rutger, FABRITIUS, Charles-Henry, GRUBER, Dorothea, FLÜCKIGER-MANGUAL, Stefanie, HEKKING, Koen F. W, VEERMAN, Johan J. N

Volltext bestellen

Heterocyclic derivatives, pharmaceutical compositions and their use in the treatment or amelioration of cancer von EERLAND, Martijn, FOLMER, Rutger, FABRITIUS, Charles-Henry, GRUBER, Dorothea, FLÜCKIGER-MANGUAL, Stefanie, HEKKING, Koen F. W, VEERMAN, Johan J. N

Volltext bestellen

HETEROCYCLIC DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND THEIR USE IN THE TREATMENT OR AMELIORATION OF CANCER von VEERMAN, JOHAN J. N, FLUCKIGER-MANGUAL, STEFANIE, GRUBER, DOROTHEA, FOLMER, RUTGER, FABRITIUS, CHARLES-HENRY, EERLAND, MARTIJN, HEKKING, KOEN F. W

Volltext bestellen

DERIVADOS HETEROCÍCLICOS, COMPOSIÇÕES FARMACÊUTICAS E SEU USO NO TRATAMENTO OU MELHORA DO CÂNCER von STEFANIE FLÜCKIGER-MANGUAL, CHARLES-HENRY FABRITIUS, DOROTHEA GRUBER, RUTGER FOLMER, KOEN F. W. HEKKING, JOHAN J. N. VEERMAN, MARTIJN EERLAND

Volltext bestellen

헤테로사이클릭 유도체, 약학 조성물 및 암의 치료 또는 개선에서 그들의 용도 von GRUBER DOROTHEA, FOLMER RUTGER, VEERMAN JOHAN J. N, HEKKING KOEN F. W, EERLAND MARTIJN, FLUCKIGER MANGUAL STEFANIE, FABRITIUS CHARLES HENRY

Volltext bestellen

HETEROCYCLIC DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND THEIR USE IN THE TREATMENT OR AMELIORATION OF CANCER von FABRITIUS Charles-henry, HEKKING Koen F. W, FLÜCKIGER-MANGUAL Stefanie, VEERMAN Johan J. N, GRUBER Dorothea, FOLMER Rutger, EERLAND Martijn

Volltext bestellen

ChemInform Abstract: Synthesis of Versatile Building Blocks Through Asymmetric Hydrogenation of Functionalized Itaconic Acid Mono-Esters von Hekking, Koen F. W., Lefort, Laurent, de Vries, Andre H. M., van Delft, Floris L., Schoemaker, Hans E., de Vries, Johannes G., Rutjes, Floris P. J. T.

Volltext

ChemInform Abstract: A Ring-Closing Metathesis Approach to Cyclic α,β-Dehydroamino Acids von Hekking, Koen F. W., Waalboer, Dennis C. J., Moelands, Marcel A. H., van Delft, Floris L., Rutjes, Floris P. J. T.

Volltext

An Efficient Synthesis of 1-Naphthylbis(oxazoline) and Exploration of the Scope in Asymmetric Catalysis von van Lingen, Hester L., van de Mortel, Jeroen K. W., Hekking, Koen F. W., van Delft, Floris L., Sonke, Theo, Rutjes, Floris P. J. T.

Volltext