Gain of 20q11.21 in human embryonic stem cells improves cell survival by increased expression of Bcl-xL von Nguyen, H T, Geens, M, Mertzanidou, A, Jacobs, K, Heirman, C, Breckpot, K, Spits, C

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A phase IB study on intravenous synthetic mRNA electroporated dendritic cell immunotherapy in pretreated advanced melanoma patients von Wilgenhof, S., Van Nuffel, A.M.T., Benteyn, D., Corthals, J., Aerts, C., Heirman, C., Van Riet, I., Bonehill, A., Thielemans, K., Neyns, B.

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Interference with PD-L1/PD-1 co-stimulation during antigen presentation enhances the multifunctionality of antigen-specific T cells von Pen, J J, Keersmaecker, B D, Heirman, C, Corthals, J, Liechtenstein, T, Escors, D, Thielemans, K, Breckpot, K

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Computational staining of CD3/CD20 positive lymphocytes in human tissues with experimental confirmation in a genetically engineered mouse model von Li, Xiang, Heirman, Casey C, Rickard, Ashlyn G, Sotolongo, Gina, Castillo, Rico, Adanlawo, Temitayo, Everitt, Jeffery I, Hodgin, Jeffery B, Watts, Tammara L, Janowczyk, Andrew, Mowery, Yvonne M, Barisoni, Laura, Lafata, Kyle J

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Downregulation of Stat3 in melanoma: reprogramming the immune microenvironment as an anticancer therapeutic strategy von Emeagi, P U, Maenhout, S, Dang, N, Heirman, C, Thielemans, K, Breckpot, K

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Development of the Nanobody display technology to target lentiviral vectors to antigen-presenting cells von Goyvaerts, C, De Groeve, K, Dingemans, J, Van Lint, S, Robays, L, Heirman, C, Reiser, J, Zhang, X-Y, Thielemans, K, De Baetselier, P, Raes, G, Breckpot, K

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Induction of effective therapeutic antitumor immunity by direct in vivo administration of lentiviral vectors von DULLAERS, M, VAN MEIRVENNE, S, HEIRMAN, C, STRAETMAN, L, BONEHILL, A, AERTS, J. L, THIELEMANS, K, BRECKPOT, K

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3328 A randomized controlled phase II clinical trial on autologous monocyte-derived mRNA electroporated dendritic cells for stage III/IV melanoma patients who are disease-free foll... von Jansen, Y, Corthals, J, Wilgenhof, S, Schreuer, M, Heirman, C, Thielemans, K, Neyns, B

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Phosphorylated STAT3 physically interacts with NPM and transcriptionally enhances its expression in cancer von Ren, Z, Aerts, J L, Pen, J J, Heirman, C, Breckpot, K, De Grève, J

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In vitro generation of mature, naive antigen-specific CD8+ T cells with a single T-cell receptor by agonist selection von Snauwaert, S, Verstichel, G, Bonte, S, Goetgeluk, G, Vanhee, S, Van Caeneghem, Y, De Mulder, K, Heirman, C, Stauss, H, Heemskerk, M H M, Taghon, T, Leclercq, G, Plum, J, Langerak, A W, Thielemans, K, Kerre, T, Vandekerckhove, B

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Electroporation of immature and mature dendritic cells: implications for dendritic cell-based vaccines von MICHIELS, A, TUYAERTS, S, VAN DER BRUGGEN, P, THIELEMANS, K, BONEHILL, A, CORTHALS, J, BRECKPOT, K, HEIRMAN, C, VAN MEIRVENNE, S, DULLAERS, M, ALLARD, S, BRASSEUR, F

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1090 Tumor-associated Antigen Validation in Uterine Tumors von Vanderstraeten, A, Tuyaerts, S, Luyten, C, Van Bree, R, Verbist, L, Heirman, C, Thielemans, K, Amant, F

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RASSF4 functions as a tumor suppressor in Multiple Myeloma von De Smedt, E, Maes, K, Verhulst, S, Heirman, C, Hose, D, Van Valckenborgh, E, Menu, E, Breckpot, K, Van Grunsven, L, Moreaux, J, De Bruyne, E

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Development of an ex vivo assay measuring T cells with indirect alloreactivity using messenger RNA electroporation von Shi, X.L, Tapirdamaz, Ö, Heirman, C, de Mare-Bredemeijer, E.L.D, Heemskerk, M.H.M, van der Laan, L.J.W, Metselaar, H.J, Thielemans, K, Kwekkeboom, J

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P4 Preclinical evaluation of an mRNA-based therapeutic HIV vaccine candidate combining rationally selected antigenic sequences and potent adjuvant signals (HTI-TriMix) von Tjok Joe, P., Guardo, A.C., Miralles, L., Bargalló, M.E., Maleno, M.J., Mothe, B., Krasniqi, A., Heirman, C., García, F., Gatell, J.M., Thielemans, K., Brander, C., Plana, M., Aerts, J.L.

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Induction of antigen-specific CD8 cytotoxic T cells by dendritic cells co-electroporated with a dsRNA analogue and tumor antigen mRNA von MICHIELS, A, BRECKPOT, K, CORTHALS, I, TUYAERTS, S, BONEHILL, A, HEIRMAN, C, THIELEMANS, K, AERTS, J. L

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Therapeutic Vaccination With an Autologous mRNA Electroporated Dendritic Cell Vaccine in Patients With Advanced Melanoma von WILGENHOF, Sofie, VAN NUFFEL, An M. T, BONEHILL, Aude, THIELEMANS, Kris, NEYNS, Bart, CORTHALS, Jurgen, HEIRMAN, Carlo, TUYAERTS, Sandra, BENTEYN, Daphné, DE CONINCK, Arlette, VAN RIET, Ivan, VERFAILLIE, Guy, VANDELOO, Judith

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P18-03. Dendritic cell-based immune therapy against HIV-1 von Gruters, RA, de Keersmaecker, B, de Goede, AL, Allard, SD, Koetsveld, J, Corthals, J, Schutten, M, Heirman, C, Ende, ME van der, Lacor, P, Osterhaus, AD, Thielemans, K, van Baalen, CA, Aerts, JL

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Messenger RNA-Electroporated Dendritic Cells Presenting MAGE-A3 Simultaneously in HLA Class I and Class II Molecules von Bonehill, Aude, Heirman, Carlo, Tuyaerts, Sandra, Michiels, Annelies, Breckpot, Karine, Brasseur, Francis, Zhang, Yi, van der Bruggen, Pierre, Thielemans, Kris

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Loading of dendritic cells for immunotherapy von Van Nuffel, A. M. T., Benteyn, D., Wilgenhof, S., Corthals, J., Heirman, C., Neyns, B., Bonehill, A., Thielemans, K.

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