Biochemical-free enrichment or depletion of RNA classes in real-time during direct RNA sequencing with RISER von Sneddon, Alexandra, Ravindran, Agin, Shanmuganandam, Somasundhari, Kanchi, Madhu, Hein, Nadine, Jiang, Simon, Shirokikh, Nikolay, Eyras, Eduardo

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Inhibition of RNA Polymerase I as a Therapeutic Strategy to Promote Cancer-Specific Activation of p53 von Bywater, Megan J., Poortinga, Gretchen, Sanij, Elaine, Hein, Nadine, Peck, Abigail, Cullinane, Carleen, Wall, Meaghan, Cluse, Leonie, Drygin, Denis, Anderes, Kenna, Huser, Nanni, Proffitt, Chris, Bliesath, Joshua, Haddach, Mustapha, Schwaebe, Michael K., Ryckman, David M., Rice, William G., Schmitt, Clemens, Lowe, Scott W., Johnstone, Ricky W., Pearson, Richard B., McArthur, Grant A., Hannan, Ross D.

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New Roles for the Nucleolus in Health and Disease von Núñez Villacís, Lorena, Wong, Mei S., Ferguson, Laura L., Hein, Nadine, George, Amee J., Hannan, Katherine M.

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Combination Therapy Targeting Ribosome Biogenesis and mRNA Translation Synergistically Extends Survival in MYC-Driven Lymphoma von Devlin, Jennifer R, Hannan, Katherine M, Hein, Nadine, Cullinane, Carleen, Kusnadi, Eric, Ng, Pui Yee, George, Amee J, Shortt, Jake, Bywater, Megan J, Poortinga, Gretchen, Sanij, Elaine, Kang, Jian, Drygin, Denis, O'Brien, Sean, Johnstone, Ricky W, McArthur, Grant A, Hannan, Ross D, Pearson, Richard B

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Inhibition of RNA polymerase I transcription initiation by CX-5461 activates non-canonical ATM/ATR signaling von Quin, Jaclyn, Chan, Keefe T, Devlin, Jennifer R, Cameron, Donald P, Diesch, Jeannine, Cullinane, Carleen, Ahern, Jessica, Khot, Amit, Hein, Nadine, George, Amee J, Hannan, Katherine M, Poortinga, Gretchen, Sheppard, Karen E, Khanna, Kum Kum, Johnstone, Ricky W, Drygin, Denis, McArthur, Grant A, Pearson, Richard B, Sanij, Elaine, Hannan, Ross D

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Phosphorylation by Cdk2 is required for Myc to repress Ras-induced senescence in cotransformation von Hydbring, Per, Bahram, Fuad, Su, Yingtao, Tronnersjö, Susanna, Högstrand, Kari, von der Lehr, Natalie, Sharifi, Hamid Reza, Lilischkis, Richard, Hein, Nadine, Wu, Siqin, Vervoorts, Jörg, Henriksson, Marie, Grandien, Alf, Lüscher, Bernhard, Larsson, Lars-Gunnar

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Identification of Burkholderia pseudomallei Genes Required for the Intracellular Life Cycle and In Vivo Virulence von Pilatz, Sabine, Breitbach, Katrin, Hein, Nadine, Fehlhaber, Beate, Schulze, Jessika, Brenneke, Birgit, Eberl, Leo, Steinmetz, Ivo

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A novel role for the Pol I transcription factor UBTF in maintaining genome stability through the regulation of highly transcribed Pol II genes von Sanij, Elaine, Diesch, Jeannine, Lesmana, Analia, Poortinga, Gretchen, Hein, Nadine, Lidgerwood, Grace, Cameron, Donald P, Ellul, Jason, Goodall, Gregory J, Wong, Lee H, Dhillon, Amardeep S, Hamdane, Nourdine, Rothblum, Lawrence I, Pearson, Richard B, Haviv, Izhak, Moss, Tom, Hannan, Ross D

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CX-5461 Preferentially Induces Top2α-Dependent DNA Breaks at Ribosomal DNA Loci von Cameron, Donald P, Sornkom, Jirawas, Alsahafi, Sameerh, Drygin, Denis, Poortinga, Gretchen, McArthur, Grant A, Hein, Nadine, Hannan, Ross, Panov, Konstantin I

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Targeting the ribosome to treat multiple myeloma von Maclachlan, Kylee H, Gitareja, Kezia, Kang, Jian, Cuddihy, Andrew, Cao, Yuxi, Hein, Nadine, Cullinane, Carleen, Ang, Ching-Seng, Brajanovski, Natalie, Pearson, Richard B, Khot, Amit, Sanij, Elaine, Hannan, Ross D, Poortinga, Gretchen, Harrison, Simon J

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rDNA Chromatin Activity Status as a Biomarker of Sensitivity to the RNA Polymerase I Transcription Inhibitor CX-5461 von Son, Jinbae, Hannan, Katherine M., Poortinga, Gretchen, Hein, Nadine, Cameron, Donald P., Ganley, Austen R. D., Sheppard, Karen E., Pearson, Richard B., Hannan, Ross D., Sanij, Elaine

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High-Content Imaging Approaches to Quantitate Stress-Induced Changes in Nucleolar Morphology von He, Jin-Shu, Soo, Priscilla, Evers, Maurits, Parsons, Kate M, Hein, Nadine, Hannan, Katherine M, Hannan, Ross D, George, Amee J

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Targeting RNA Polymerase I Transcription Activity in Osteosarcoma: Pre-Clinical Molecular and Animal Treatment Studies von Kang, Chang-Won, Blackburn, Anneke C, Loh, Amos Hong Pheng, Hong, Kuick Chick, Goh, Jian Yuan, Hein, Nadine, Drygin, Denis, Parish, Chris R, Hannan, Ross D, Hannan, Katherine M, Coupland, Lucy A

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Purification of Mouse Embryonic Fibroblasts (MEFs) von Ferreira, Rita, Hein, Nadine

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The nucleolus: an emerging target for cancer therapy von Hein, Nadine, Hannan, Katherine M, George, Amee J, Sanij, Elaine, Hannan, Ross D

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Advanced pancreatic ductal adenocarcinoma - Complexities of treatment and emerging therapeutic options von Diwakarla, Chandra, Hannan, Katherine, Hein, Nadine, Yip, Desmond

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First-in-Human RNA Polymerase I Transcription Inhibitor CX-5461 in Patients with Advanced Hematologic Cancers: Results of a Phase I Dose-Escalation Study von Khot, Amit, Brajanovski, Natalie, Cameron, Donald P, Hein, Nadine, Maclachlan, Kylee H, Sanij, Elaine, Lim, John, Soong, John, Link, Emma, Blombery, Piers, Thompson, Ella R, Fellowes, Andrew, Sheppard, Karen E, McArthur, Grant A, Pearson, Richard B, Hannan, Ross D, Poortinga, Gretchen, Harrison, Simon J

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Profiling age and body fluid DNA methylation markers using nanopore adaptive sampling von Yuen, Zaka Wing-Sze, Shanmuganandam, Somasundhari, Stanley, Maurice, Jiang, Simon, Hein, Nadine, Daniel, Runa, McNevin, Dennis, Jack, Cameron, Eyras, Eduardo

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The Ribosomal Gene Loci-The Power behind the Throne von Panov, Konstantin I., Hannan, Katherine, Hannan, Ross D., Hein, Nadine

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Novel Combination Therapy Targeting rDNA Transcription and Histone Deacetylation Provides Effective Treatment for Multiple Myeloma, and Synergises in Bortezomib-Resistant MM von Maclachlan, Kylee H, Cuddihy, Andrew, Hein, Nadine, Cullinane, Carleen, Harrison, Simon J., Hannan, Ross, Poortinga, Gretchen

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